It's always nice when a local boy makes good in the big wide world. Many British neuroscientists and psychiatrists have been feeling rather proud this week following the enormous amount of attention given to Professor David Nutt, formerly the British government's chief adviser on illegal drugs.Formerly being the key word. Nutt was sacked (...write your own "nutsack" pun if you must) last Friday, prompting a remarkable amount of condemnation. Critics included the rest of his former organisation, ........ Read more »
by Nestor Lopez-Duran PhD in Child-Psych
Recently I finished writing an article with child depression researcher Dr. Maria Kovacs about the concept of prodromal processes in child and adolescent depression. The article should be appearing early next year on a special issue of the Journal of Child Psychology and Psychiatry. In that article, we reviewed the extensive literature on the predictors [...]... Read more »
Gallerani, C., Garber, J., & Martin, N. (2009) The temporal relation between depression and comorbid psychopathology in adolescents at varied risk for depression. Journal of Child Psychology and Psychiatry. DOI: 10.1111/j.1469-7610.2009.02155.x
The Journal of Experimental Biology has published an interesting paper about some unique features in sprinters: longer toes and shorter ankle joints. The only one flaw is that their sample size is limited, they only compared 12 collegiate sprinters with 12 non-athletes of the same height. Regardless, from a physical anthropological point of view, this [...]... Read more »
Lee, S., & Piazza, S. (2009) Built for speed: musculoskeletal structure and sprinting ability. Journal of Experimental Biology, 212(22), 3700-3707. DOI: 10.1242/jeb.031096
patients with depression often complain of difficulty getting to sleep, frequent awakenings during the night, early morning awakening, or nonrestorative sleep
patients with mood disorders exhibit higher rates of sleep disturbance than the general population, and sleep disturbance can continue even during periods of remission
patients with insomnia are up to 10 times more likely to have [...]
Related posts:Winter Depression Or Seasonal Affective Disorder It’s the time of year again, th........ Read more »
As I continue to catch up on my articles, this post is about an article by Rambold and colleagues that was published in the Journal of Neurochemistry. The researchers’ study was designed to identify compounds that would interfere with the propagation of the pathologic prion protein. The two compounds investigated in the present article were the main components of green tea, epigallocatechin gallate (EGCG) and gallocatechin gallate (GCG). This was an in vitro study that us........ Read more »
Rambold, A., Miesbauer, M., Olschewski, D., Seidel, R., Riemer, C., Smale, L., Brumm, L., Levy, M., Gazit, E., Oesterhelt, D.... (2008) Green tea extracts interfere with the stress-protective activity of PrP and the formation of PrP . Journal of Neurochemistry, 107(1), 218-229. DOI: 10.1111/j.1471-4159.2008.05611.x
This is another geeky post. If you are currently having treatment for cancer the research described in this post will not alter your treatment as this work is being carried out in cells in a laboratory (and not in people) but it is very interesting and will hopefully be used to design new treatments in [...]... Read more »
Valastyan S, Reinhardt F, Benaich N, Calogrias D, Szász AM, Wang ZC, Brock JE, Richardson AL, & Weinberg RA. (2009) A pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis. Cell, 137(6), 1032-46. PMID: 19524507
Aging is associated with well described changing in sleep patterns.
Total sleep time decreases, elderly sleep less
It takes longer before falling a sleep
Elderly go to bed earlier and they awake earlier
There sleep architecture has changed, the slow wave sleep on EEG is reduced, REM sleep is reduced
They’re easier aroused from sleep
They sleep fragmented with many arousals
No related posts.
Related posts brought to you by Yet Another Related Posts Plugin.... Read more »
Wolkove, N., Elkholy, O., Baltzan, M., & Palayew, M. (2007) Sleep and aging: 1. Sleep disorders commonly found in older people. Canadian Medical Association Journal, 176(9), 1299-1304. DOI: 10.1503/cmaj.060792
Wolkove, N., Elkholy, O., Baltzan, M., & Palayew, M. (2007) Sleep and aging: 2. Management of sleep disorders in older people. Canadian Medical Association Journal, 176(10), 1449-1454. DOI: 10.1503/cmaj.070335
*Hot* News via Twitter and various news media a few days ago. Big headlines tell the following in respectively The Sun, Herald, Ireland, BBC News / NHS Health and Reuters:
Curry is a ‘cure for cancer‘
Spices in curry may help cure cancer
Curry spice ‘kills cancer cells‘
Scientists say curry compound kills cancer cells
The message of these headlines [...]... Read more »
O'Sullivan-Coyne, G., O'Sullivan, G., O'Donovan, T., Piwocka, K., & McKenna, S. (2009) Curcumin induces apoptosis-independent death in oesophageal cancer cells. British Journal of Cancer, 101(9), 1585-1595. DOI: 10.1038/sj.bjc.6605308
López-Lázaro, M. (2008) Anticancer and carcinogenic properties of curcumin: Considerations for its clinical development as a cancer chemopreventive and chemotherapeutic agent. Molecular Nutrition . DOI: 10.1002/mnfr.200700238
Castedo, M., Perfettini, J., Roumier, T., Andreau, K., Medema, R., & Kroemer, G. (2004) Cell death by mitotic catastrophe: a molecular definition. Oncogene, 23(16), 2825-2837. DOI: 10.1038/sj.onc.1207528
Valery Fortie is the National Awareness Coordinator of
Mediterraneanbook.com, a directory of news source focused on healthy
eating habits. The author suggests that the Mediterranean Diet can help ward off many diseases and illnesses.
One of those serious and potentially life threatening diseases is breast
cancer. With a risk of one in seven people developing breast cancer in
their lifetime, [...]... Read more »
Cottet, V., Touvier, M., Fournier, A., Touillaud, M., Lafay, L., Clavel-Chapelon, F., & Boutron-Ruault, M. (2009) Postmenopausal Breast Cancer Risk and Dietary Patterns in the E3N-EPIC Prospective Cohort Study. American Journal of Epidemiology, 170(10), 1257-1267. DOI: 10.1093/aje/kwp257
I came across a very cool study last week which was published in the latest issue of the American Journal of Preventive Medicine. In this new paper, Dr Gabrielle Turner-McGrievy and colleagues at the University of North Carolina at Chapel Hill examined the impact of listening to a weight-loss podcast on body weight, physical activity, and fruit and vegetable consumption in overweight men and women. Subjects were randomly allocated to one of two groups; the control group which received a popular ........ Read more »
Turner-McGrievy, G., Campbell, M., Tate, D., Truesdale, K., Bowling, J., & Crosby, L. (2009) Pounds Off Digitally StudyA Randomized Podcasting Weight-Loss Intervention. American Journal of Preventive Medicine, 37(4), 263-269. DOI: 10.1016/j.amepre.2009.06.010
A recent review about the relationship between exercise and mental health in the elderly discussed the results of clinical research and biological explanations for the effects of exercise on mental health. Exercise is studied in the elderly in depression, Alzheimer’s disease and Parkinson’s disease.
We’ve discussed the topic of exercise and depression before on this blog. [...]
Related posts:Exercise and Depression According to a recent review of reviews it is...Neuroscienc........ Read more »
I spent about 45 minutes yesterday in the local HMO clinic. They had turned the main waiting room into a Pandemic Novel A/H1N1 Swine (nee Mexican) Influenza quarantine area, and I could feel the flu viruses poking at my skin looking for a way in the whole time I was there.
Read the rest of this post... | Read the comments on this post...... Read more »
Reed, C, Angulo, F., Swerdow, D, Lipsitch, M, Meltzer, M, Jeernigan, F., & Harvard School of Public Health. (2009) Estimates of the Prevalence of Pandemic (H1N1) 2009, United States, April–July 2009 . Emerging Infectiou Diseases, 15(11). info:/
When researchers at the Washington University School of Medicine published the first longitudinal study of Major Depressive Disorder (MDD) in preschool children, it came as a surprise to many that...... Read more »
Luby JL, Si X, Belden AC, Tandon M, & Spitznagel E. (2009) Preschool depression: homotypic continuity and course over 24 months. Archives of general psychiatry, 66(8), 897-905. PMID: 19652129
When researchers at the Washington University School of Medicine published the first longitudinal study of Major Depressive Disorder (MDD) in preschool children, it came as a surprise to many that...
... Read more »
Luby, J., Si, X., Belden, A., Tandon, M., & Spitznagel, E. (2009) Preschool Depression: Homotypic Continuity and Course Over 24 Months. Archives of General Psychiatry, 66(8), 897-905. DOI: 10.1001/archgenpsychiatry.2009.97
Low Back Disorders: Evidence-Based Prevention and Rehabilitation. 2nd Edition. Stuart McGill, PhD. Human Kinetics, 2007. 312 pages.
Dr. Stuart McGill and his immense research based out of the University of Waterloo, Ontario can be summarized in this 2nd edition of Low Back Disorders. Although, the back is often seen as complex by many health professions alike, Dr. McGill’s book helps to put things into a perspective which is easy to understand. The book is divided into three par........ Read more »
Boyd, K. (2003) Low Back Disorders: Evidence-Based Prevention and Rehabilitation. Physiotherapy Canada, 55(02), 124. DOI: 10.2310/6640.2003.37832
Back in June, I discussed the results of a large epidemiological study in women that showed that women with larger breasts have an increased risk of developing type-2 diabetes.
As soon as Travis and I read this study, we knew we had to do a follow-up study of our own to see if this finding was simply spurious or if there was actually something to large breasts that indicated health risk – beyond that explained by obesity per se.
The project that Travis and I began over a year ago has........ Read more »
Janiszewski, P., Saunders, T., & Ross, R. (2009) Breast Volume is an Independent Predictor of Visceral and Ectopic Fat in Premenopausal Women. Obesity. DOI: 10.1038/oby.2009.336
Apparently, the FDA will approve just about anything as an antidepressant. Despite patients indicating that they don't perceive Abilify to work as an antidepressant, the FDA approved it, likely leading to tens of thousands of Americans being able to enjoy a taste of akathisia while getting all the psychological benefits of a placebo. Good work, FDA. The shift of antipsychotics into antidepressants has been documented in many places and is, ironically, very depressing (1, 2, 3, 4).The FDA's "a........ Read more »
O’Reardon, J., Solvason, H., Janicak, P., Sampson, S., Isenberg, K., Nahas, Z., McDonald, W., Avery, D., Fitzgerald, P., & Loo, C. (2007) Efficacy and Safety of Transcranial Magnetic Stimulation in the Acute Treatment of Major Depression: A Multisite Randomized Controlled Trial. Biological Psychiatry, 62(11), 1208-1216. DOI: 10.1016/j.biopsych.2007.01.018
Yu, E., & Lurie, P. (2009) Transcranial Magnetic Stimulation Not Proven Effective. Biological Psychiatry. DOI: 10.1016/j.biopsych.2009.03.026
Understand why neck pain is such a reoccurring problem in the health care field. Are you treating the pain or the cause?... Read more »
O’Leary, S. (2009) Muscle Dysfunction in Cervical Spine Pain: Implications for Assessment and Management. Journal of Orthopaedic and Sports Physical Therapy. DOI: 10.2519/jospt.2009.2872
By: Rosemary Stephen, Elements: Environmental Health Intelligence
Every year millions of people go on pilgrimages. Pilgrims are classified into three groups: ‘religious pilgrims’ who visit religious shrines, ‘cultural pilgrims’ who visit places of cultural significance and ‘notable pilgrims’ high ranking individuals and leaders who travel for personal and political reasons . Religious pilgrims, in particular, are [...]... Read more »
Rosemary Stephen. (2009) Pilgrims and H1N1. Elements: Environmental Health Intelligence. info:/
According to a study in the Journal of Health Psychology, I have just increased the likelihood that you will...... Read more »
Godin, G., Sheeran, P., Conner, M., & Germain, M. (2008) Asking questions changes behavior: Mere measurement effects on frequency of blood donation. Health Psychology, 27(2), 179-184. DOI: 10.1037/0278-6126.96.36.199
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