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  • March 14, 2014
  • 01:05 PM
  • 17 views

Could Sir Elton John be immune to HIV?

by Stuart Farrimond in Dr Stu's Science Blog

It is a little known fact that some people are born with an immunity to HIV/AIDS. Such a person could be exposed to infection again and again and yet not contract the illness. They are the lucky ones. But more than that, they could also be the ones who hold the cure for the world. … Continue reading →... Read more »

  • March 13, 2014
  • 01:35 PM
  • 100 views

I gained two stone in weight since stopping smoking 10 months ago – why?

by Stuart Farrimond in Guru: Science Blog

Gaining weight is one of the most feared consequences to stopping smoking. So firstly, good on you for kicking the cigarettes. The majority of people will gain some weight after stopping smoking. On average, ex-smokers put on a couple of […]The post I gained two stone in weight since stopping smoking 10 months ago – why? appeared first on Guru Magazine.... Read more »

  • March 13, 2014
  • 12:11 PM
  • 97 views

Outcome in REM Sleep Behavior Disorder

by William Yates, M.D. in Brain Posts

This is the second in series of posts examining recent research in sleep and the brain.Rapid eye movement (REM) sleep behavior disorder is a complex sleep problem seen primarily in older adults.REM, or dream sleep, typically occurs with atonia.  Atonia is the temporary state of muscle paralysis.  This prohibits muscular activity or acting out during dream states.With REM sleep behavior disorder, atonia is not present with REM sleep resulting in motor restlessness, agitation and occasio........ Read more »

Iranzo A, Fernández-Arcos A, Tolosa E, Serradell M, Molinuevo JL, Valldeoriola F, Gelpi E, Vilaseca I, Sánchez-Valle R, Lladó A.... (2014) Neurodegenerative Disorder Risk in Idiopathic REM Sleep Behavior Disorder: Study in 174 Patients. PloS one, 9(2). PMID: 24587002  

  • March 12, 2014
  • 07:41 PM
  • 140 views

Canines and Castles: 4th Canine Science Forum Abstract & Early Bird Registration Deadline Friday

by Cobb & Hecht in Do You Believe In Dog?

“Two canine scientists, Julie Hecht and Mia Cobb, met briefly at a conference in Barcelona in late July 2012. They share a passion for canine science, good communication, social media and fun.” So reads the 'About' page at Do You Believe in Dog?. After a brief hello at the 3rd Canine Science Forum in Barcelona, we decided to embark on an adventure as digital pen pals, taking turns blogging on topics related to our own research, that of other research groups and general dog science themes.&n........ Read more »

Cobb Mia, Branson Nick, & McGreevy Paul. (2013) Advancing the welfare of Australia’s iconic working dogs. Journal of Veterinary Behavior: Clinical Applications and Research, 8(4). DOI: 10.1016/j.jveb.2013.04.054  

Hecht J., & Horowitz A. (2013) Physical prompts to anthropomorphism of the domestic dog (Canis familiaris). Journal of Veterinary Behavior: Clinical Applications and Research, 8(4). DOI: 10.1016/j.jveb.2013.04.013  

Racca A., Range F., Virányi Z., & Huber L. (2013) Discrimination of familiar human faces in domestic dogs. Journal of Veterinary Behavior: Clinical Applications and Research, 8(4). DOI: 10.1016/j.jveb.2013.04.071  

Howell Tiffani J., Toukhsati Samia, Conduit Russell, & Bennett Pauleen. (2013) Do dogs use a mirror to find hidden food?. Journal of Veterinary Behavior: Clinical Applications and Research, 8(6), 425-430. DOI: 10.1016/j.jveb.2013.07.002  

  • March 12, 2014
  • 03:00 PM
  • 54 views

MMR’s successor – MMRV

by Tarnjit Khera in Scitkk

MMRV is the quadruple vaccination against measles, mumps and rubella (MMR; more here) and chicken pox (also known as varicella). Varicella vaccination (developed in Japan) has been used in Japan for twenty years and in the USA since 1995. In 2006, the varicella vaccination was combined with MMR to make MMRV. MMRV was licensed in 2005 and is a routine vaccination in many countries including the USA, Germany and Australia. The advantages of this are to reduce the number of injections and therefore........ Read more »

Tarnjit Khera. (2014) MMR’s successor – MMRV. Scitkk.WordPress.com. info:other/

  • March 12, 2014
  • 10:16 AM
  • 94 views

New Evidence on the Benefits of Sprinting for Long-Term Health and Fitness

by AB Kirk in Stiff Competition

Benefits Sprinting and Jumping: New Evidence I began distance running at the age of 12 and have kept with it for decades now. Running at a mellow pace has helped me unwind, de-stress and keep my sanity through turbulent times. Until I started CrossFit about five years ago. While I miss the runners high there […]The post New Evidence on the Benefits of Sprinting for Long-Term Health and Fitness appeared first on WODMasters.... Read more »

Gast U, Belavý DL, Armbrecht G, Kusy K, Lexy H, Rawer R, Rittweger J, Winwood K, Zieliński J, & Felsenberg D. (2013) Bone density and neuromuscular function in older competitive athletes depend on running distance. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 24(7), 2033-42. PMID: 23242430  

  • March 12, 2014
  • 05:46 AM
  • 107 views

Pain predicting sleep problems in autism

by Paul Whiteley in Questioning Answers

Not so long ago I talked about the paper from Smith and colleagues [1] on autism and obstacles to medical [comorbidity] diagnosis and treatment (see here). Aside from the need for professionals to overcome the issue of "a lack of expressive speech" as an impediment to undertaking a thorough medical work-up when presented with a person with autism, an important theme of that paper was the requirement to see beyond autism as being the 'reason' for every single behaviour or issue that aff........ Read more »

Tudor ME, Walsh CE, Mulder EC, & Lerner MD. (2014) Pain as a predictor of sleep problems in youth with autism spectrum disorders. Autism : the international journal of research and practice. PMID: 24497628  

  • March 11, 2014
  • 11:55 PM
  • 91 views

Who Needs a 12 Lead ECG?

by Rogue Medic in Rogue Medic

Do we do too many 12 lead ECGs on patients who do not have chest pain?

This is something that some people worry about.

Save the electrodes!

Those poor little electrodes are being abused!

Are electrodes being abused?... Read more »

  • March 11, 2014
  • 11:33 AM
  • 91 views

Variant Prioritization in Rare Mendelian Disorders

by Daniel Koboldt in Massgenomics

Few areas of biomedical research have benefited more from next-gen sequencing than studies of rare inherited diseases. Rapid, inexpensive exome sequencing in individuals with rare, presumably-monogenic diseases has been hugely successful over the past few years. There’s been a lot of discussion in the NGS community about the analysis burden of the large-scale whole-genome sequencing […]... Read more »

Koboldt DC, Larson DE, Sullivan LS, Bowne SJ, Steinberg KM, Churchill JD, Buhr AC, Nutter N, Pierce EA, Blanton SH.... (2014) Exome-Based Mapping and Variant Prioritization for Inherited Mendelian Disorders. American journal of human genetics. PMID: 24560519  

  • March 11, 2014
  • 11:09 AM
  • 94 views

Depression-related Sleep Abnormalities Vary By Age

by William Yates, M.D. in Brain Posts

This month I will be focusing on sleep and the brain. The importance of sleep to normal and abnormal brain functioning is receiving increased research attention.A variety of sleep abnormalities have been described in major depression and bipolar affective disorder. Depression has been linked to delayed sleep onset, reduced time to first rapid eye movement (REM) period, reduced sleep efficiency and disruption of the circadian rhythm of sleep.Sleep physiology also varies throughout the lifesp........ Read more »

Robillard, R., Naismith, S., Smith, K., Rogers, N., White, D., Terpening, Z., Ip, T., Hermens, D., Whitwell, B., Scott, E.... (2014) Sleep-Wake Cycle in Young and Older Persons with a Lifetime History of Mood Disorders. PLoS ONE, 9(2). DOI: 10.1371/journal.pone.0087763  

  • March 10, 2014
  • 05:39 AM
  • 99 views

Acute psychosis and urinary tract infection

by Paul Whiteley in Questioning Answers

Today I'm highlighting the paper by Krystle Graham and colleagues [1] which talked about a possible association between the presence of urinary tract infections (UTIs) in various types of psychosis. With my interest in all things biology-behaviour, remembering such posts as impulsivity and uric acid (see here), once again we have an example of how the two areas just might fit together.The bullfighter (deceased) @Manet @Wikipedia So, take several groups of adult........ Read more »

Graham KL, Carson CM, Ezeoke A, Buckley PF, & Miller BJ. (2014) Urinary tract infections in acute psychosis. The Journal of clinical psychiatry. PMID: 24499998  

  • March 9, 2014
  • 01:00 PM
  • 92 views

Prehistoric Giant Virus Found

by Chiara Civardi in United Academics

Prehistoric giant virus buried in the Siberian ice recovered from a scientific expedition. No, it is not the plot of “The Thing”, but the utter truth: a thirty- thousand- year old virus, whose dimensions are 50 times bigger than the ones of average virus from today, was found by Abergel and Claverie’s team in the Russian permafrost.... Read more »

Legendre M, Bartoli J, Shmakova L, Jeudy S, Labadie K, Adrait A, Lescot M, Poirot O, Bertaux L, Bruley C.... (2014) Thirty-thousand-year-old distant relative of giant icosahedral DNA viruses with a pandoravirus morphology. Proceedings of the National Academy of Sciences of the United States of America. PMID: 24591590  

Philippe N, Legendre M, Doutre G, Couté Y, Poirot O, Lescot M, Arslan D, Seltzer V, Bertaux L, Bruley C.... (2013) Pandoraviruses: amoeba viruses with genomes up to 2.5 Mb reaching that of parasitic eukaryotes. Science (New York, N.Y.), 341(6143), 281-6. PMID: 23869018  

  • March 9, 2014
  • 11:42 AM
  • 104 views

Pregnancy and breast cancer risk: why age counts

by EE Giorgi in CHIMERAS

That an early pregnancy is protective against breast cancer is something I've known for ten years now. I remember one of my professors, back when I started studying genetics, saying: "Having a baby at 16 may ruin your life but it sure protects you from breast cancer." Today we know a lot more about the cellular and genetic mechanisms that a first pregnancy triggers in the body. And yet how these mechanisms turn out to be protective against breast cancer is still a mystery. "The ovarian hormones,........ Read more »

Medina D. (2005) Mammary developmental fate and breast cancer risk. Endocrine-related cancer, 12(3), 483-95. PMID: 16172188  

Meier-Abt F, & Bentires-Alj M. (2014) How pregnancy at early age protects against breast cancer. Trends in molecular medicine, 20(3), 143-153. PMID: 24355762  

  • March 7, 2014
  • 04:40 AM
  • 132 views

Autoimmune diseases and schizophrenia

by Paul Whiteley in Questioning Answers

The paper by Michael Benrós and colleagues [1] talking about an "increased risk of subsequent autoimmune diseases in individuals with schizophrenia" caught my eye recently. Based on a trawl of the records of several thousands of people with "schizophrenia-like psychosis" or "individuals with autoimmune disease" derived from Danish nationwide registers (see here for some background), the authors were able to conclude that "Autoimmune diseases developed subsequently in 3.6% of people wi........ Read more »

  • March 7, 2014
  • 02:15 AM
  • 139 views

How intensive care is linked to cognitive defecits

by Rebekah Morrow in United Academics

Patients in the Intensive Care Unit (ICU) often develop cognitive deficits. The symptoms are very similar to Alzheimer’s and other forms of dementia. New research focuses on this link. ... Read more »

Pandharipande PP1, Girard TD, Jackson JC, Morandi A, Thompson JL, Pun BT, Brummel NE, Hughes CG, Vasilevskis EE, Shintani AK, Moons KG, Geevarghese SK, Canonico A, Hopkins RO, Bernard GR, Dittus RS, Ely EW; BRAIN-ICU Study Investigators. (2014) Long-Term Cognitive Impairment after Critical Illness. New England Journal of Medicine, 370(2), 184-186. DOI: 10.1056/NEJMc1313886  

  • March 5, 2014
  • 11:20 PM
  • 131 views

Attachment: measuring our (varying) relationships with dogs.

by Cobb & Hecht in Do You Believe In Dog?

Hi Julie,Right off the bat I need to say YES YES YES! Your last post about aggression and what we can learn from and about it WITHOUT the need to experience it was spot on. Are you THIS attached to your dog? (source)You’re also right that my head is filled with glorious meta-analysis results right now, as well as perceptions and other measures (#allthemeasures!) as I start preparing my abstracts for submission to be part of the Canine Science Forum. One of the small but quirky things........ Read more »

Dwyer Fleur, Bennett Pauleen C., & Coleman Grahame J. (2006) Development of the Monash Dog Owner Relationship Scale (MDORS). Anthrozoos: A Multidisciplinary Journal of The Interactions of People , 19(3), 243-256. DOI: 10.2752/089279306785415592  

Handlin Linda, Nilsson Anne, Ejdebäck Mikael, Hydbring-Sandberg Eva, & Uvnäs-Moberg Kerstin. (2012) Associations between the Psychological Characteristics of the Human–Dog Relationship and Oxytocin and Cortisol Levels. Anthrozoos: A Multidisciplinary Journal of The Interactions of People , 25(2), 215-228. DOI: 10.2752/175303712X13316289505468  

  • March 5, 2014
  • 04:23 PM
  • 107 views

High protein diet is protective for older people, but may be unhealthy for others

by AB Kirk in Stiff Competition

We’ve written several articles on the apparent benefits of a higher protein diet for the older athlete.  Loss of muscle mass starts fairly early and loss of strength is often apparent by middle age.  We do not know how much protein intake is ideal for humans.  High protein diets for older people have been geared […]The post High protein diet is protective for older people, but may be unhealthy for others appeared first on WODMasters.... Read more »

Gregorio L, Brindisi J, Kleppinger A, Sullivan R, Mangano KM, Bihuniak JD, Kenny AM, Kerstetter JE, & Insogna KL. (2014) Adequate Dietary Protein is Associated with Better Physical Performance among Post-Menopausal Women 60-90 Years. The journal of nutrition, health , 18(2), 155-60. PMID: 24522467  

Beasley JM, Wertheim BC, LaCroix AZ, Prentice RL, Neuhouser ML, Tinker LF, Kritchevsky S, Shikany JM, Eaton C, Chen Z.... (2013) Biomarker-calibrated protein intake and physical function in the Women's Health Initiative. Journal of the American Geriatrics Society, 61(11), 1863-71. PMID: 24219187  

  • March 5, 2014
  • 03:28 PM
  • 106 views

Direct Access and the six month dental recall: Taking decisions in uncertainty.

by Kevin OBrien in Kevin OBrien's Orthodontic Blog

Direct Access and the Six Month Dental recall: Taking decisions in uncertainty? This blog today is not about orthodontics, but it is about the interpretation of situations where there is a “lack of evidence” underpinning decisions. As a result, this is very relevant to all the clinical decisions that we may make in the face […]The post Direct Access and the six month dental recall: Taking decisions in uncertainty. appeared first on Kevin O'Brien's Orthodontic Blog.... Read more »

  • March 5, 2014
  • 03:15 PM
  • 113 views

Drug resistance evolves in inbred parasites

by sedeer in Inspiring Science

It all starts with a mosquito bite. When a hungry mosquito pierces someone’s skin to gorge herself, she also pumps …Continue reading →... Read more »

Miotto O, Almagro-Garcia J, Manske M, Macinnis B, Campino S, Rockett KA, Amaratunga C, Lim P, Suon S, Sreng S.... (2013) Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia. Nature genetics, 45(6), 648-55. PMID: 23624527  

  • March 5, 2014
  • 03:00 PM
  • 126 views

The Failure of LUCAS to Improve Outcomes in the LINC Trial

by Rogue Medic in Rogue Medic

We love gadgets in EMS.

Dr. Bryan Bledsoe tells us that if we paint it orange and put a star of life on it, we can sell any product for a lot more money.

How much would you pay to not improve outcomes?

$10,000.00?

$20,000.00?

$30,000.00?

$40,000.00?

$50,000.00?... Read more »

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