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  • February 11, 2015
  • 05:22 AM
  • 106 views

Like buses. Vitamin D and autism again.

by Paul Whiteley in Questioning Answers

I don't know if everyone will have heard the term 'like buses' to infer that you seem to spend ages waiting for something (like a bus) and then two or more turn up at once. So it is with research, and the continuing interest that autism research seems to have with the sunshine vitamin/hormone that is vitamin D.Following on from my recent discussions on the paper by Fernell and colleagues [1] (see here) talking about early low vitamin D potentially being 'connected' to cases of autism or autism s........ Read more »

  • February 10, 2015
  • 04:09 PM
  • 110 views

New name: Systemic Exertion Intolerance Disease?

by Paul Whiteley in Questioning Answers

The name is: Systematic Exertion Intolerance Disease (SEID).A very quick post to direct you to the public release of the findings from the US Institute of Medicine (IoM) looking at the name and current criteria used to diagnose Chronic Fatigue Syndrome / Myalgic Encephalomyelitis (CFS/ME) (see here). The proposed diagnostic criteria for CFS/ME, sorry SEID can be viewed here.Some of the background to these findings can be seen here and some of the media about the new IoM recommendations can ........ Read more »

  • February 10, 2015
  • 02:43 PM
  • 85 views

Measles Mumps Rubella Vaccine in Adults: CDC Reports Excellent Safety Record

by Marie Benz in MedicalResearch.com

MedicalResearch.com Medical Research Interviews and News
MedicalResearch.com Interview with: Rachel Pryzby, MPH, CHES Health Communications Specialist Chenega Government Consulting Immunization Safety Office, Division of Healthcare Quality Promotion Centers for Disease Control and Prevention Medical Research: What is the background for this study? What are the main … Continue reading →
The post Measles Mumps Rubella Vaccine in Adults: CDC Reports Excellent Safety Record appeared fir........ Read more »

MedicalResearch.com Interview with:, & Rachel Pryzby, MPH, CHES. (2015) Measles Mumps Rubella Vaccine in Adults: CDC Reports Excellent Safety Record. MedicalResearch.com. info:/

  • February 10, 2015
  • 01:16 PM
  • 75 views

Primary Care Intervention Program Increased Physical Activity in Women

by Marie Benz in MedicalResearch.com

MedicalResearch.com Medical Research Interviews and News
MedicalResearch.com Interview with: Molly B. Conroy MD, MPH Assistant Professor of Medicine, Epidemiology, and Clinical and Translational Science University of Pittsburgh, Pittsburgh, PA, Medical Research: What is the background for this study? What are the main findings? Response: The background … Continue reading →
The post Primary Care Intervention Program Increased Physical Activity in Women appeared first on MedicalResear........ Read more »

MedicalResearch.com Interview with:, & Molly B. Conroy MD, MPH. (2015) Primary Care Intervention Program Increased Physical Activity in Women. MedicalResearch.com. info:/

  • February 10, 2015
  • 01:06 PM
  • 89 views

Seafood associated with autoimmune disease

by Dr. Jekyll in Lunatic Laboratories

Autoimmunity is one of those great mysteries of the human body. We still aren’t sure what causes it and treating it can be painfully ineffective. Unfortunately my sister knows that one first hand, so here at the labs autoimmunity is a problem close to our heart. While we may not know what causes autoimmunity, a new study suggests one of the greatest risk factors for autoimmunity among women of childbearing age may be associated with exposure to mercury such as through seafood.... Read more »

  • February 10, 2015
  • 12:25 PM
  • 90 views

Lowering Blood Pressure Reduces Complications in Diabetes

by Marie Benz in MedicalResearch.com

MedicalResearch.com Medical Research Interviews and News
MedicalResearch.com Interview with: Prof. Kazem Rahimi  DM MSc FESC Associate Professor of Cardiovascular Medicine, University of Oxford ;Deputy Director, The George Institute for Global Health; James Martin Fellow in Healthcare Innovation, Oxford Martin School; Honorary Consultant Cardiologist, Oxford University Hospitals NHS Trust … Continue reading →
The post Lowering Blood Pressure Reduces Complications in Diabetes appe........ Read more »

Prof. KAZEM RAHIMI | DM MSc FESC Associate Professor of Cardiovascular Medicine, University of Oxford Deputy Director, The George Institute for Global Health James Martin Fellow in Healthcare Innovation, Oxford Martin School Honorary Consultant Cardiologi, & Prof. Kazem Rahimi DM MSc FESC. (2015) Lowering Blood Pressure Reduces Complications in Diabetes. MedicalResearch.com. info:/

  • February 10, 2015
  • 04:53 AM
  • 90 views

Increased risk of chronic kidney disease in schizophrenia

by Paul Whiteley in Questioning Answers

"After adjusting for demographic characteristics, select comorbid medical disorders and NSAIDs [non-steroid anti-inflammatory drugs] usage, the current results reveal that patients with schizophrenia have an increased risk of nearly 40% (HR=1.36; 95% CI 1.13 to 1.63; p<0.001) of developing CKD [chronic kidney disease] within a 3-year follow-up period after their schizophrenia diagnosis."That was the rather surprising finding reported by Nian-Sheng Tzeng and colleagues........ Read more »

  • February 9, 2015
  • 04:34 PM
  • 112 views

Help on the horizon for treatment resistant depression

by Dr. Jekyll in Lunatic Laboratories

Depression is like a kick while you’re already down. Sometimes there is no real reason for it, sometimes it is triggered by some serious life issues, but clinical depression always has very real neurological roots. Unfortunately, while we know that certain areas of the brain are smaller in a depressed person, we don’t know why or what effect it has on a person. Worse, SSRI’s the “gold standard” for depression can have no — or worse ill — effects on the person taking the drugs.... Read more »

Benjamin D. Sachs, Jason R. Ni, & Marc G. Caron. (2015) Brain 5-HT deficiency increases stress vulnerability and impairs antidepressant responses following psychosocial stress. Proceedings of the National Academy of Sciences of the United States of America. info:/10.1073/pnas.1416866112

  • February 9, 2015
  • 11:21 AM
  • 117 views

The Beginnings of Jurassic Park: Dinosaur Blood Discovered? (A Guest Post)

by Miss Behavior in The Scorpion and the Frog

By Samantha VoldThe classic tale of Jurassic Park, where dinosaurs once again walked the earth has tickled the fancy of many a reader. Dinosaur DNA preserved in a fossilized mosquito was used to bring these giants back to life. But in real life, it was previously thought that there was no possible way for organic materials to be preserved, that they often degraded within 1 million years if not rapidly attacked by bacteria and other organisms specialized in decomposition. Skin and other soft tiss........ Read more »

Schweitzer, M. (2010) Blood from Stone. Scientific American, 303(6), 62-69. DOI: 10.1038/scientificamerican1210-62  

  • February 9, 2015
  • 10:56 AM
  • 72 views

Not All Living Kidney Donor Kidneys Are Created Equal

by Cristy at Living Donor 101 in Living Donors Are People Too

Our authors looked at the effect of single kidney glomerular filtration rate and/or donor/recipient body surface area ration affected graft function post-transplant. Give the whole study a read here: http://informahealthcare.com/doi/abs/10.3109/0886022X.2015.1007805 But in short, they found that SKGFR <40 is a problem, as is D/R BSA <0.8. The larger the donor/recipient body surface area ratio the better in …
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The post Not All Living Kidney Donor Kidneys Ar........ Read more »

  • February 9, 2015
  • 08:00 AM
  • 11 views

Feeding Mental Health Through Nutritional Interventions

by amikulak in Daily Observations

Major depression affects many millions of people worldwide and is one of the leading causes of disability, according to data from the World Health Organization. Diagnosing and treating depression is, […]... Read more »

  • February 9, 2015
  • 04:47 AM
  • 109 views

What have we learned about autism?

by Paul Whiteley in Questioning Answers

Today's post is a bit of mash-up based on the review paper by Jason Chen and colleagues [1] and a news entry from Autism Speaks titled: '10 Years of Progress: What We've Learned About Autism' (see here). Cumulatively, these two commentaries try to paint a picture of where we are, knowledge-wise, when it comes to the label of autism or autism spectrum disorder (ASD) and highlight the many gaps that remain in what we 'think' we know about autism.The Chen paper approaches the 'emerging picture of a........ Read more »

Chen JA, Peñagarikano O, Belgard TG, Swarup V, & Geschwind DH. (2015) The Emerging Picture of Autism Spectrum Disorder: Genetics and Pathology. Annual review of pathology, 111-144. PMID: 25621659  

  • February 8, 2015
  • 03:11 PM
  • 112 views

‘Virtual virus’ unfolds the flu on a CPU

by Dr. Jekyll in Lunatic Laboratories

The flu virus can be pretty nasty — it’s quick to evolve — which means yearly flu shots are needed and then it’s only a guess to which strain will be the most prevalent. Well new research aims to change all that, by combining experimental data from X-ray crystallography, NMR spectroscopy, cryoelectron microscopy and lipidomics (the study of cellular lipid networks), researchers have built a complete model of the outer envelope of an influenza A virion for the first time. So would that ma........ Read more »

Reddy, T., Shorthouse, D., Parton, D., Jefferys, E., Fowler, P., Chavent, M., Baaden, M., & Sansom, M. (2015) Nothing to Sneeze at: A Full-Scale Computational Model of the Human Influenza Virion. Biophysical Journal, 108(2), 31. DOI: 10.1016/j.bpj.2014.11.195  

  • February 7, 2015
  • 09:21 PM
  • 143 views

Misinformation and selective coverage change perception of outbreaks, but can be corrected by presenting the facts

by Austin Bouck in Fur, Farm, & Fork

While it’s not an animal product, the Listeriosis outbreak recently traced to apples is just as relevant to the food industry as a whole as any other food-borne illness outbreak. While I was looking for more information on the outbreak, I came across this gem* of an article posted on cnn.com.... Read more »

  • February 7, 2015
  • 03:37 PM
  • 126 views

Anorexia, it’s in your genes

by Dr. Jekyll in Lunatic Laboratories

No one likes to talk about eating disorders — specifically anorexia nervosa — despite the increased prevalence in both men and women. Like depression people tend to think that you can “just get over it” or some other nonsense. However new research is shedding light on the truth behind anorexia, much like with depression, there is a biological component involved. Simply put, it gets written into your genes.... Read more »

Howard Steiger Et al. (2015) DNA methylation in individuals with Anorexia Nervosa and in matched normal-eater controls: A genome-wide study. International Journal of Eating Disorders. info:/10.1002/eat.19378

  • February 7, 2015
  • 12:50 PM
  • 62 views

Distressing End of Life Symptoms Common and Often Untreated

by Marie Benz in MedicalResearch.com

MedicalResearch.com Medical Research Interviews and News
MedicalResearch.com Interview with: Adam E. Singer, MPhil Pardee RAND Graduate School, RAND Corporation Santa Monica, CA MedicalResearch: What is the background for this study? What are the main findings? Response: In 1997, the Institute of Medicine (IOM) released a seminal … Continue reading →
The post Distressing End of Life Symptoms Common and Often Untreated appeared first on MedicalResearch.com Medical Research Interviews........ Read more »

MedicalResearch.com Interview with:, Adam E. Singer, MPhil, Pardee, RAND Graduate School, RAND Corporation, & Santa Monica, CA. (2015) Distressing End of Life Symptoms Common and Often Untreated. MedicalResearch.com. info:/

  • February 7, 2015
  • 12:23 PM
  • 63 views

MOVE! VA Lifestyle Program Linked To Lower Diabetes Incidence

by Marie Benz in MedicalResearch.com

MedicalResearch.com Medical Research Interviews and News
MedicalResearch.com Interview with: Dr Sandra L Jackson PhD  Atlanta VA Medical Center, Decatur, GA, Nutrition and Health Sciences, Graduate Division of Biological and Biomedical Sciences Emory University, Atlanta, GA, USA Medical Research: What is the background for this study? What are the … Continue reading →
The post MOVE! VA Lifestyle Program Linked To Lower Diabetes Incidence appeared first on MedicalResearch.com Med........ Read more »

MedicalResearch.com Interview with:, Dr Sandra L Jackson PhD, & Atlanta VA Medical Center, Decatur, GA, Nutrition and Health Sciences, Graduate Division of Biological and Biomedical Sciences. (2015) MOVE! VA Lifestyle Program Linked To Lower Diabetes Incidence. MedicalResearch.com. info:/

  • February 7, 2015
  • 04:00 AM
  • 118 views

Over a third of US children will have a behavioural / emotional disorder by 16 years of age

by Paul Whiteley in Questioning Answers

I had to do a second-take when it came to the clinical report from Carol Weitzman and colleagues [1] (open-access here) talking about promoting 'optimal development'  and "the need to increase behavioral screening" when it comes to the children and youth of the United States.The title of this post kinda said it all derived from the sentence: "Between 37% and 39% of children will have a behavioral or emotional disorder diagnosed by 16 years of age, regardless of geographic location in t........ Read more »

Carol Weitzman, Lynn Wegner, & et al. (2015) Promoting Optimal Development: Screening for Behavioral and Emotional Problems. Pediatrics. info:/10.1542/peds.2014-3716

  • February 6, 2015
  • 04:51 PM
  • 135 views

Scientists find a way to treat hormone deficiency from an unlikely source

by Dr. Jekyll in Lunatic Laboratories

Science has helped us to live longer and in some cases much fuller lives. Unfortunately for some with serious medical conditions, they may lead a long life, but a life of what? To that end a group of researchers set out to help people with hormone deficiencies and the team has developed a potential new therapy based on an unlikely model: immune molecules from cows.... Read more »

Liu Tao, Yan Liu, Ying Wang, Haiqun Jia, Mingchao Kang, Xiaozhou Luo, Dawna Caballero, Jose Gonzalez, Lance Sherwood, & Vanessa Nunez. (2015) Functional human antibody CDR fusions as long-acting therapeutic endocrine agonists. Proceedings of the National Academy of Sciences, 112(5), 1356-1361. DOI: http://dx.doi.org/10.1073/pnas.1423668112  

  • February 6, 2015
  • 12:56 PM
  • 45 views

Related Kidney Donors Need Aftercare and Support

by Cristy at Living Donor 101 in Living Donors Are People Too

This study from 2004, entitled “Psychological effects of living related kidney transplantation – risks and chances“, looked at 31 donor-recipient pairs. It concludes:   A. Living kidney donor transplantation is stressful for recipients, donors *and* their families, B. The recipient’s post-transplant health affects the donor’s psychological well-being. [Note: Yet another reason to focus on the quality …
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