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  • July 9, 2014
  • 05:52 AM
  • 68 views

Familial Recurrence of Autism Spectrum Disorder (again)

by Paul Whiteley in Questioning Answers

The paper by Neil Risch and colleagues [1] adds to the growing literature looking at the question of familial recurrence of autism i.e. if one child has a diagnosis of autism, how likely are subsequent children to be similarly diagnosed. The answer according to this latest data: "The overall sibling recurrence risk was 10.1%" compared with 0.5% in siblings of asymptomatic controls. This figure is pretty much the same as that reported by Sandin and colleagues [2] covered not so long ago (see here........ Read more »

  • July 8, 2014
  • 02:17 PM
  • 83 views

Skin Cells and Skin… smells?!

by Gabriel in Lunatic Laboratories

Yeah we all know that your nose smells. Yawn! Boring I know, this isn’t kindergarten this is Loony Labs! Thankfully that isn’t what I have for you [as much as […]... Read more »

Busse, D., Kudella, P., Grüning, N., Gisselmann, G., Ständer, S., Luger, T., Jacobsen, F., Steinsträßer, L., Paus, R., Gkogkolou, P.... (2014) A Synthetic Sandalwood Odorant Induces Wound Healing Processes in Human Keratinocytes via the Olfactory Receptor OR2AT4. Journal of Investigative Dermatology. DOI: 10.1038/jid.2014.273  

  • July 8, 2014
  • 11:15 AM
  • 67 views

Millions Lack Level I Trauma Care Access in the U.S.

by William Yates, M.D. in Brain Posts

Trauma results in 180,000 deaths per year in the U.S. and disproportionately affects children and young adults. The Centers for Disease Control (CDC) recently published a review highlighting unintentional injury and violence as the leading cause of death in the U.S. for those in the one to 30 year old age group. Additionally, trauma produces significant disability through residual effects such as like that often seen following traumatic brain injury.Trauma centers are hospital-affiliat........ Read more »

Haegerich, T., Dahlberg, L., Simon, T., Baldwin, G., Sleet, D., Greenspan, A., & Degutis, L. (2014) Prevention of injury and violence in the USA. The Lancet, 384(9937), 64-74. DOI: 10.1016/S0140-6736(14)60074-X  

Garwe T, Cowan LD, Neas B, Cathey T, Danford BC, & Greenawalt P. (2010) Survival benefit of transfer to tertiary trauma centers for major trauma patients initially presenting to nontertiary trauma centers. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 17(11), 1223-32. PMID: 21175521  

Bukur M, Felder SI, Singer MB, Ley EJ, Malinoski DJ, Margulies DR, & Salim A. (2013) Trauma center level impacts survival for cirrhotic trauma patients. The journal of trauma and acute care surgery, 74(4), 1133-7. PMID: 23511156  

MacKenzie, E., Weir, S., Rivara, F., Jurkovich, G., Nathens, A., Wang, W., Scharfstein, D., & Salkever, D. (2010) The Value of Trauma Center Care. The Journal of Trauma: Injury, Infection, and Critical Care, 69(1), 1-10. DOI: 10.1097/TA.0b013e3181e03a21  

  • July 8, 2014
  • 05:25 AM
  • 78 views

Coenzyme Q10 and autism

by Paul Whiteley in Questioning Answers

The paper by Frederick Crane and colleagues [1] (open-access here) caught my eye recently and their suggestion that when it comes to autism there may be more research to do on coenzyme Q10. Indeed, the old grey-pinkish matter started grinding into action as to whether there may be a wider research literature on CoQ10 with a focus on autism...A helping hand? @ Wikipedia Coenzyme Q10 otherwise known as ubiquinone, has appeared before on this blog for various reasons (see here and se........ Read more »

Crane FL, Löw H, Sun I, Navas P, & Gvozdjáková A. (2014) Plasma membrane coenzyme Q: evidence for a role in autism. Biologics : targets , 199-205. PMID: 24920882  

  • July 7, 2014
  • 11:27 PM
  • 71 views

The Refs are Biased, Neurologically

by Allison in Dormivigilia

During the last World Cup, a study was published that outlined why the human eye and human perception is fatly at certain angles. ... Read more »

Kranjec A, Lehet M, Bromberger B, Chatterjee A. (2010) A Sinister Bias for Calling Fouls in Soccer. PLoS One, 5(7). info:/10.1371/journal.pone.0011667

  • July 7, 2014
  • 04:09 PM
  • 101 views

Is there such a thing as an anti-depression diet?

by AB Kirk in Stiff Competition

Summary: People who suffer from depression seem to experience more oxidative stress and inflammation than others.  A diet high in anti-oxidants, fermentable fiber and low in saturated and transfats may protect against inflammatory stress in the brain and elsewhere.  More research needed.  The topic is under investigation. Introduction: We recently posted an article about the […]
The post Is there such a thing as an anti-depression diet? appeared first on WODMasters: Stiff Co........ Read more »

Moylan S, Berk M, Dean OM, Samuni Y, Williams LJ, O'Neil A, Hayley AC, Pasco JA, Anderson G, Jacka FN.... (2014) Oxidative . Neuroscience and biobehavioral reviews, 46-62. PMID: 24858007  

Maslowski KM, Vieira AT, Ng A, Kranich J, Sierro F, Yu D, Schilter HC, Rolph MS, Mackay F, Artis D.... (2009) Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43. Nature, 461(7268), 1282-6. PMID: 19865172  

Pistell PJ, Morrison CD, Gupta S, Knight AG, Keller JN, Ingram DK, & Bruce-Keller AJ. (2010) Cognitive impairment following high fat diet consumption is associated with brain inflammation. Journal of neuroimmunology, 219(1-2), 25-32. PMID: 20004026  

  • July 7, 2014
  • 01:27 PM
  • 110 views

Staying up late? You’re going Crazy

by Gabriel in Lunatic Laboratories

All night cram sessions, anyone in college has probably had more than just a few of these [okay maybe only if you are a procrastinator like me]. If you have […]... Read more »

  • July 7, 2014
  • 10:50 AM
  • 75 views

The Geography of Traumatic Brain Injury Death in U.S.

by William Yates, M.D. in Brain Posts

In the last post, I examined some recent research in the epidemiology of traumatic brain injury (TBI).Two studies showed the top two causes of TBI to be motor vehicle crashes and falls.In this post, I will review some recent data on the geographic variability of TBI in the United States.The Centers for Disease Control provides an online tool called WISQARS that allows users to search for a variety of statistics related to unintentional injury by state in the U.S.They have recently added a iPad a........ Read more »

Centers for Disease Control and Prevention (CDC). (2013) CDC grand rounds: reducing severe traumatic brain injury in the United States. MMWR. Morbidity and mortality weekly report, 62(27), 549-52. PMID: 23842444  

  • July 7, 2014
  • 07:09 AM
  • 22 views

Revealed: The Secret Of An Intellectual Brain

by Shyamali Sharma in Workout Trends

“Do you love to write? I do… Do you prefer typing rather than writing? I do…” Well, I might sound like a bride standing on the altar in front of my groom. The priest asks me the most obvious questions and I nonchalantly reply, “Yes, I do.” Students and tech savvy people are also most likely […]
The post Revealed: The Secret Of An Intellectual Brain appeared first on .
... Read more »

  • July 7, 2014
  • 03:18 AM
  • 112 views

Reproductive stoppage related to autism

by Paul Whiteley in Questioning Answers

The paper by Thomas Hoffmann and colleagues [1] on reproductive stoppage - the decision to not have more children - in couples with a child already diagnosed with an autism spectrum disorder (ASD) is the source for today's post. This is both an important and delicate area to talk about so I tread very carefully in my discussions.The Holy Infants @ Wikipedia A few details first:Based on records held at the California Department of Developmental Services, children born between 1990 ........ Read more »

  • July 6, 2014
  • 01:10 PM
  • 115 views

New tool helps Doctors treat Menopause

by Gabriel in Lunatic Laboratories

With the SCOTUS ruling for the Hobby Lobby case [if you have no idea what I am talking about you can read about that anywhere on the net, like here] […]... Read more »

  • July 6, 2014
  • 09:30 AM
  • 30 views

Day 5: BLUE and PURPLE Foods

by Namrata Diengdoh in Workout Trends

Whenever I close my eyes and imagine the color purple the first thought that comes to my mind is royalty. So does blue does it not? However, when I think blue it brings more serenity to my thoughts. Did you know that this color food group helps people who are looking forward to losing weight? […]
The post Day 5: BLUE and PURPLE Foods appeared first on .
... Read more »

García-Zepeda SP, García-Villa E, Díaz-Chávez J, Hernández-Pando R, & Gariglio P. (2013) Resveratrol induces cell death in cervical cancer cells through apoptosis and autophagy. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 22(6), 577-84. PMID: 23603746  

Krikorian, R., Shidler, M., Nash, T., Kalt, W., Vinqvist-Tymchuk, M., Shukitt-Hale, B., & Joseph, J. (2010) Blueberry Supplementation Improves Memory in Older Adults . Journal of Agricultural and Food Chemistry, 58(7), 3996-4000. DOI: 10.1021/jf9029332  

  • July 5, 2014
  • 01:00 PM
  • 100 views

Breast Cancer… and Cholesterol?!

by Gabriel in Lunatic Laboratories

Cholesterol, it’s bad for the heart. We know LDL bad, HDL good, eat healthier or ruin your arteries. I’m sure most of us have seen the public service announcements [at […]... Read more »

Potluri, R., Lavu, D., Uppal, H., & Chandran, S. (2014) P740 Hyperlipidaemia as a risk factor for breast cancer?. Cardiovascular Research, 103(suppl 1). DOI: 10.1093/cvr/cvu098.160  

  • July 5, 2014
  • 08:31 AM
  • 23 views

Day 4: Cleansing With WHITE Foods

by Namrata Diengdoh in Workout Trends

  “If I have been indulging in rich foods, a cleanse is a wonderful way to hit the reset button.” - Salma Hayek Now are not those beautiful words and don’t those words hold so much weight in them. If we think carefully and analyze our life pattern in the present time then it is […]
The post Day 4: Cleansing With WHITE Foods appeared first on .
... Read more »

Padayatty, S., Katz, A., Wang, Y., Eck, P., Kwon, O., Lee, J., Chen, S., Corpe, C., Dutta, A., Dutta, S.... (2003) Vitamin C as an Antioxidant: Evaluation of Its Role in Disease Prevention. Journal of the American College of Nutrition, 22(1), 18-35. DOI: 10.1080/07315724.2003.10719272  

Handley, S., Dunn, T., Waldron, G., & Baker, J. (1980) Tryptophan, cortisol and puerperal mood. The British Journal of Psychiatry, 136(5), 498-508. DOI: 10.1192/bjp.136.5.498  

Shukla, Y., & Singh, M. (2007) Cancer preventive properties of ginger: A brief review. Food and Chemical Toxicology, 45(5), 683-690. DOI: 10.1016/j.fct.2006.11.002  

McCarron, D., Morris, C., Henry, H., & Stanton, J. (1984) Blood pressure and nutrient intake in the United States. Science, 224(4656), 1392-1398. DOI: 10.1126/science.6729459  

  • July 4, 2014
  • 02:00 PM
  • 44 views

OhMyDog! Discover The Ins And Outs Of Your Pet, And Yourself

by Elisabeth Buhl Thubron in United Academics

A new health collar or chip may be the next big accessory for dogs, and humans.... Read more »

Xu S, Zhang Y, Jia L, Mathewson KE, Jang KI, Kim J, Fu H, Huang X, Chava P, Wang R.... (2014) Soft microfluidic assemblies of sensors, circuits, and radios for the skin. Science (New York, N.Y.), 344(6179), 70-4. PMID: 24700852  

  • July 4, 2014
  • 01:00 PM
  • 155 views

Finally! A Definite Cause of Autism: Hint it isn’t Vaccines

by Gabriel in Lunatic Laboratories

Autism, not caused by vaccines. In fact I’ve written several posts on the genetic clues to autism, now a new study offers more proof that it is purely genetic [at […]... Read more »

Bernier, R., Golzio, C., Xiong, B., Stessman, H., Coe, B., Penn, O., Witherspoon, K., Gerdts, J., Baker, C., Vulto-van Silfhout, A.... (2014) Disruptive CHD8 Mutations Define a Subtype of Autism Early in Development. Cell. DOI: 10.1016/j.cell.2014.06.017  

  • July 4, 2014
  • 04:53 AM
  • 100 views

DNA methylation patterns and autism: buccal up

by Paul Whiteley in Questioning Answers

"The results indicate the presence of a mosaic subpopulation of epigenetically-dysregulated, ectodermally-derived cells in subjects with ASD [autism spectrum disorder]". That was the very clinical primary conclusion reached in the study by Esther Berko and colleagues [1] (open-access here). They looked at DNA methylation patterns in cheek cell samples for a small sample of children diagnosed with an ASD (n=47) "born to mothers aged 35 and over" compared with samples from an asymptomatic control ........ Read more »

Berko ER, Suzuki M, Beren F, Lemetre C, Alaimo CM, Calder RB, Ballaban-Gil K, Gounder B, Kampf K, Kirschen J.... (2014) Mosaic epigenetic dysregulation of ectodermal cells in autism spectrum disorder. PLoS genetics, 10(5). PMID: 24875834  

  • July 3, 2014
  • 07:44 PM
  • 96 views

This Month in Blastocystis Research (JUN 2014) - IMECs Edition

by Christen Rune Stensvold in Blastocystis Parasite Blog

A rare and extremely timely study using NGS tools to sequence DNA from intestinal microbial eukaryotic communities has been published in June 2014 in Frontiers in Microbiology; here's a small review.... Read more »

Parfrey, L., Walters, W., Lauber, C., Clemente, J., Berg-Lyons, D., Teiling, C., Kodira, C., Mohiuddin, M., Brunelle, J., Driscoll, M.... (2014) Communities of microbial eukaryotes in the mammalian gut within the context of environmental eukaryotic diversity. Frontiers in Microbiology. DOI: 10.3389/fmicb.2014.00298  

  • July 3, 2014
  • 01:00 PM
  • 134 views

Why you Should Not Fear Testosterone Therapy

by Gabriel in Lunatic Laboratories

Testosterone, to some it’s a bad word, bringing crazy images like “roid rage” and the like. To others with more than just a pop culture understanding it is a lifesaver. […]... Read more »

  • July 3, 2014
  • 11:50 AM
  • 115 views

Epidemiology of Traumatic Brain Injury (TBI)

by William Yates, M.D. in Brain Posts

Traumatic brain injury (TBI) contributes significantly to mortality and long-term disability.In the U.S. there are an estimated 52,000 deaths yearly due to TBI with over 1,000,000 emergency room (ER) visits.Understanding the epidemiology of TBI can provides clues to designing prevention programs.Four relevant recent research studies provide insight about the epidemiology of TBI.TBI in hospitalized patients in Scotland Tara Shivaji and colleagues in Scotland examined the prevalence and patte........ Read more »

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