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  • May 1, 2015
  • 03:05 PM
  • 134 views

US clinics avoiding government oversight of ‘stem cell’ treatments

by Dr. Jekyll in Lunatic Laboratories

Clinics across the United States are advertising stem cell treatments that attempt to take advantage of what they perceive as exceptions in FDA regulations.The therapies in question are adipose-derived autologous stem cell treatments, in which fat cells are removed from a patient, broken down to separate components that purportedly contain stem cells, and are then reinjected into the same patient.... Read more »

  • May 1, 2015
  • 05:00 AM
  • 167 views

Severe mental illness and victims of crime

by Paul Whiteley in Questioning Answers

"In conclusion, victimisation among people with SMI [severe mental illness] is more prevalent and associated with greater psychosocial morbidity than victimisation among the general population."That was the finding reported by Hind Khalifeh and colleagues [1] (open-access here) following their analysis of "the prevalence and impact of crime among people with SMI compared with the general population." SMI, by the way, covered various labels including: "people with psychotic disorde........ Read more »

Khalifeh H, Johnson S, Howard LM, Borschmann R, Osborn D, Dean K, Hart C, Hogg J, & Moran P. (2015) Violent and non-violent crime against adults with severe mental illness. The British journal of psychiatry : the journal of mental science. PMID: 25698767  

  • April 30, 2015
  • 07:41 PM
  • 115 views

This Month in Blastocystis Research (APR 2015)

by Christen Rune Stensvold in Blastocystis Parasite Blog

A post on trending Blastocystis research and on advances in the discoveries of plant extracts with anti-Blastocystis activity.... Read more »

  • April 30, 2015
  • 06:00 PM
  • 166 views

The Avengers: Is It Possible Someone Could Turn Into A Hulk?

by Bill Sullivan in The 'Scope

In anticipation of the return of THE AVENGERS, we take a look at the science that could possibly help someone to turn into a HULK.... Read more »

  • April 30, 2015
  • 04:26 PM
  • 138 views

Pesticides alter bees’ brains, making them unable to live and reproduce adequately

by Dr. Jekyll in Lunatic Laboratories

A new report suggests that a particular class of pesticides called “neonicotinoids” wreaks havoc on the bee populations, ultimately putting some crops that rely on pollination in jeopardy. Specifically, these pesticides kill bee brain cells, rendering them unable to learn, gather food and reproduce. The report, however, also suggests that the effects of these pesticides on bee colonies may be reversible by decreasing or eliminating the use of these pesticides on plants pollinated by bees and........ Read more »

  • April 30, 2015
  • 10:35 AM
  • 132 views

Bupropion: A Non-stimulant ADHD Drug Treatment

by William Yates, M.D. in Brain Posts

Stimulant drugs including dextroamphetamine (Adderall) and methylphenidate (Ritalin) remain among the most common and effective drug treatments for attention deficit hyperactivity disorder (ADHD).Alternative to stimulant drugs are needed to expand treatment options for clinicians and patients.One problem with the stimulants is the potential for misuse and diversion of prescription drugs to illicit drug use.One non-stimulant FDA approved drug (atomoxetine/Strattera) is available in the U.S.An add........ Read more »

  • April 30, 2015
  • 04:27 AM
  • 153 views

The prevalence of autism spectrum disorder is not increasing in childhood

by Paul Whiteley in Questioning Answers

The title of this post is an excerpt from the paper by Sebastian Lundström and colleagues [1] (open-access) who set out to "compare the annual prevalence of the autism symptom phenotype and of registered diagnoses for autism spectrum disorder during a 10 year period in children" living in Sweden. Based on two datasets - the Child and Adolescent Twin Study in Sweden and the Swedish national patient register (NPR) - researchers analysed the records of well over a million ........ Read more »

  • April 29, 2015
  • 03:12 PM
  • 194 views

Psychologists share the three secrets to healthier eating

by Dr. Jekyll in Lunatic Laboratories

You don’t need a crazy diet to lose weight. In fact, your typical fad diet won’t help you keep weight off long term and could be harming your health. If you want to know the secrets of healthier eating, think of the kitchen fruit bowl. A fruit bowl makes fruit more convenient, attractive, and normal to eat than if the same fruit were in the bottom of the refrigerator.... Read more »

  • April 29, 2015
  • 11:08 AM
  • 155 views

How Much Exercise Do You Really Need?

by Shawn Radcliffe in Shawn Radcliffe | Health and Science Writer

The benefits of exercise are clear, but how much should you be doing each week? And how hard should you work out? It turns out that most of us could stand to squeeze more exercise into our day. But we can probably get away with moderate exercise like walking. Exercising Lags Behind Screen Time If […]
The post How Much Exercise Do You Really Need? appeared first on Shawn Radcliffe.
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  • April 29, 2015
  • 08:56 AM
  • 44 views

Low Kidney Function Associated With Cognitive Impairment

by Cristy at Living Donor 101 in Living Donors Are People Too

“Chronic kidney disease (CKD) has a well-established association with impairment on neurocognitive tests, particularly measures of frontal/executive function” “MCI [Mild Cognitive Impairment] is a transitional state between normative cognitive aging and dementia. MCI is  often divided into amnestic (aMCI) form, with reduced memory performance and nonamnestic forms (naMCI), with reduced performance in cognitive domains other …
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  • April 29, 2015
  • 04:41 AM
  • 136 views

The International Classification of Functioning, Disability and Health (ICF) core sets for autism

by Paul Whiteley in Questioning Answers

"The International Classification of Functioning, Disability and Health (ICF) is a framework for describing and organising information on functioning and disability. It provides a standard language and a conceptual basis for the definition and measurement of health and disability."That is the US CDC - Centers for Disease Control and Prevention - definition of the ICF (from WHO) and how, among other things, the ICF offers a "scientific basis for understanding and studying health an........ Read more »

  • April 28, 2015
  • 02:44 PM
  • 126 views

The adolescent brain on alcohol: Changes last into adulthood

by Dr. Jekyll in Lunatic Laboratories

Repeated alcohol exposure during adolescence results in long-lasting changes in the region of the brain that controls learning and memory, according to a research team at Duke Medicine that used a rodent model as a surrogate for humans. The study provides new insights at the cellular level for how alcohol exposure during adolescence, before the brain is fully developed, can result in cellular and synaptic abnormalities that have enduring, detrimental effects on behavior.... Read more »

Risher, M., Fleming, R., Risher, W., Miller, K., Klein, R., Wills, T., Acheson, S., Moore, S., Wilson, W., Eroglu, C.... (2015) Adolescent Intermittent Alcohol Exposure: Persistence of Structural and Functional Hippocampal Abnormalities into Adulthood. Alcoholism: Clinical and Experimental Research. DOI: 10.1111/acer.12725  

  • April 28, 2015
  • 07:03 AM
  • 133 views

Mind-blowing Brain Cases: The Woman With Half A Brain

by Elisabeth Buhl Thubron in United Academics

Chinese woman without a cerebellum gives insight into neuroplasticity.... Read more »

  • April 28, 2015
  • 04:36 AM
  • 118 views

Melatonin and leaky gut continued

by Paul Whiteley in Questioning Answers

The paper from Garth Swanson and colleagues [1] reporting findings suggesting that "suppression of melatonin in AD [alcohol use disorder] may promote gut leakiness and endotoxemia" make for the discussion point today.Continuing a theme from previous times on this blog that "melatonin may serve important gastrointestinal barrier functions" [2] and specifically those related to the concept of intestinal permeability and the so-called 'leaky gut' (see here), these are potentially imp........ Read more »

Swanson GR, Gorenz A, Shaikh M, Desai V, Forsyth CB, Fogg L, Burgess HJ, & Keshavarzian A. (2015) Decreased Melatonin Secretion is Associated with Increased Intestinal Permeability and Marker of Endotoxemia in Alcoholics. American journal of physiology. Gastrointestinal and liver physiology. PMID: 25907689  

  • April 27, 2015
  • 10:50 AM
  • 111 views

ADHD and Vehicular Accident Risk

by William Yates, M.D. in Brain Posts

Attention and impulsive behaviors found in attention deficit hyperactivity disorder (ADHD) can contribute to accident risk in children and adults.A recent study of adult drivers in France provides evidence for increased accident risk in adults with ADHD.Researchers at the Bordeaux University Hospital interviewed a series of adult drivers seen in the emergency department following a road traffic crash.A total of 777 eligible subjects completed assessments of accident information, distraction expo........ Read more »

  • April 27, 2015
  • 08:41 AM
  • 34 views

Kidney Donors’ Cholesterol Linked To Kidney Disease

by Cristy at Living Donor 101 in Living Donors Are People Too

The authors examined 292 living kidney donors a median 14 months post-donation and found that renal function (GFR) was associated with Total Cholesterol and Low-Density Lipoprotein levels.   “The likelihood of CKD [chronic kidney disease, as defined by a glomerular filtration rate < 60 mL/min/1.73 m2] at last follow-up was greater in [living kidney] donors with elevated [total cholesterol] …
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The post Kidney Donors’ Cholesterol Linked To Kid........ Read more »

Yoon, Y., Choi, K., Kim, K., Yang, S., & Han, W. (2015) Clinical Assessment of Lipid Profiles in Live Kidney Donors. Transplantation Proceedings, 47(3), 584-587. DOI: 10.1016/j.transproceed.2014.12.035  

  • April 27, 2015
  • 04:36 AM
  • 134 views

When optimal outcome in autism meets ESSENCE

by Paul Whiteley in Questioning Answers

I recently came across the paper by Martina Barnevik Olsson and colleagues [1] (open-access) and their rather interesting take on the issue of optimal outcome and autism (see here for some background on this concept).Based on the idea that a diagnosis of autism or autism spectrum disorder (ASD) might not be as immutable as perhaps once thought (as in 'no longer meeting the diagnostic criteria for the condition'), Barnevik Olsson et al reported that loss of the autism/ASD label does not........ Read more »

Barnevik Olsson, M., Westerlund, J., Lundström, S., Giacobini, M., Fernell, E., & Gillberg, C. (2015) “Recovery” from the diagnosis of autism – and then?. Neuropsychiatric Disease and Treatment, 999. DOI: 10.2147/NDT.S78707  

  • April 25, 2015
  • 01:59 PM
  • 145 views

Mental disorders do not predict violence, so please stop

by Dr. Jekyll in Lunatic Laboratories

When Sandy Hook happened, it was so shocking that to this day, some don’t actually believe it happened. Shortly after, something frustrating happened, the shooter was labeled with aspergers. This helped drive the mental health and violence connection to the point that Time came out with an article dispelling that myth. Even now according to new longitudinal study of delinquent youth, most psychiatric disorders – including depression — do not predict future violent behavior. The only except........ Read more »

Elkington, K., Teplin, L., Abram, K., Jakubowski, J., Dulcan, M., & Welty, L. (2015) Psychiatric Disorders and Violence: A Study of Delinquent Youth After Detention. Journal of the American Academy of Child , 54(4), 302-31200000. DOI: 10.1016/j.jaac.2015.01.002  

  • April 25, 2015
  • 03:27 AM
  • 150 views

Kids with autism: a highly [psychotropic] medicated group?

by Paul Whiteley in Questioning Answers

"In keeping with international studies this sample of children with ASD [autism spectrum disorder] was a highly medicated group."So said the results of the study reported by Kerry-Ann Louw and colleagues [1] back in 2013 who noted that approximately one quarter of their cohort were currently in receipt of "psychotropic medications". I don't want to linger too much on this topic given that such findings tally with other peer-reviewed reports including those with much larger partici........ Read more »

  • April 24, 2015
  • 04:19 PM
  • 187 views

Diabetes drug found in freshwater potential cause of intersex fish

by Dr. Jekyll in Lunatic Laboratories

A medication commonly taken for Type II diabetes, which is being found in freshwater systems worldwide, has been shown to cause intersex in fish –or male fish that produce eggs. The study determined exposure to the diabetes medicine metformin causes physical changes in male fish exposed to doses similar to the amount in wastewater effluent.... Read more »

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