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  • February 3, 2016
  • 03:06 PM
  • 724 views

Investigating potential fetal exposure to antidepressants

by Dr. Jekyll in Lunatic Laboratories

Depression is a serious issue for expecting mothers. Left untreated, depression could have implications for a fetus’s health. But treating the disease during pregnancy may carry health risks for the developing fetus, which makes an expecting mother’s decision whether to take medication a very difficult one. To better understand how antidepressants affect fetuses during pregnancy, scientists studied exposure in mice.

... Read more »

  • February 2, 2016
  • 03:03 PM
  • 729 views

Depressed or inflamed? Inflammation attacks brain’s reward center

by Dr. Jekyll in Lunatic Laboratories

Inflammation is a good thing, it helps the body fight disease, and without it we wouldn't survive. Unfortunately, when inflammation isn't kept under control it can wreak havoc on the body. From potentially causing alzheimer's to arthritis it seems that unchecked inflammation can cause all sorts of issues. In fact, a new study adds to the list of issues out of control inflammation causes in the body.

... Read more »

  • February 2, 2016
  • 11:18 AM
  • 582 views

Postmodern Stress Disorder – New psychological problem

by Usman Paracha in SayPeople

Main Point:

“Postmodern Stress Disorder” is considered as a relatively new psychological disorder caused by repetitive exposure to violent images and other such things.

Published in:

The American Journal of Medicine

Study Further:

In a study by a researcher from Drexel University College of Medicine, Philadelphia, Postmodern Stress Disorder has been described as a new disorder that is almost similar to posttraumatic stress disorder, in which a person start feeling stre........ Read more »

  • February 1, 2016
  • 04:14 PM
  • 673 views

Schizophrenia, Hubris and Science

by Neuroskeptic in Neuroskeptic_Discover





A press-release from the Harvard-MIT Broad Institute reaches astonishing heights of hyperbole in announcing a new schizophrenia study (Sekar et al. 2016). Here's the release:
Genetic study provides first-ever insight into biological origin of schizophrenia

Landmark analysis reveals excessive "pruning" of connections between neurons in brain predisposes to schizophrenia

A landmark study, based on genetic analysis of nearly 65,000 people, has revealed that a person’s risk of schizo... Read more »

Sekar A, Bialas AR, de Rivera H, Davis A, Hammond TR, Kamitaki N, Tooley K, Presumey J, Baum M, Van Doren V.... (2016) Schizophrenia risk from complex variation of complement component 4. Nature. PMID: 26814963  

  • February 1, 2016
  • 03:41 PM
  • 600 views

Blood pressure medicine may improve conversational skills of individuals with autism

by Dr. Jekyll in Lunatic Laboratories

An estimated 1 in 68 children in the United States has autism. The neurodevelopmental disorder, which impairs communication and social interaction skills, can be treated with medications and behavioral therapies, though there is no cure. Now, University of Missouri researchers have found that a medication commonly used to treat high blood pressure and irregular heartbeats may have the potential to improve some social functions of individuals with autism.

... Read more »

  • January 31, 2016
  • 02:57 PM
  • 902 views

The brains of patients with schizophrenia vary depending on the type of schizophrenia

by Dr. Jekyll in Lunatic Laboratories

I have a friend who lost an eye to his brother. Yes, you read that correctly, his brother tried to kill him and in the process he lost his eye. I’ve told this story before, but whenever new schizophrenia research comes out I feel the need to tell it again. While he has forgiven his brother (partly because not long after, he was diagnosed as schizophrenic), he will not be able to see him again until he is released from prison. A tragedy that could’ve been avoided had he been diagnosed sooner......... Read more »

  • January 31, 2016
  • 07:09 AM
  • 953 views

Coal tar, dyes, and the unlikely origins of psychotherapeutic drugs

by neurosci in Neuroscientifically Challenged










While it may be difficult to imagine in a day and age when psychiatric medicines are advertised as a way to treat nearly every mental disorder, only 65 years ago targeted and effective psychiatric medicines were still just an unrealized aspiration. In fact, until the middle of the 20th century, the efficacy and safety of many common approaches to treating mental illness were highly questionable. For example, one method of treating schizophrenia that was common in the 1940s........ Read more »

López-Muñoz, F., Alamo, C., cuenca, E., Shen, W., Clervoy, P., & Rubio, G. (2005) History of the Discovery and Clinical Introduction of Chlorpromazine. Annals of Clinical Psychiatry, 17(3), 113-135. DOI: 10.1080/10401230591002002  

  • January 30, 2016
  • 03:21 PM
  • 600 views

Neurological adaptations to the presence of toxic HIV protein

by Dr. Jekyll in Lunatic Laboratories

Nearly half of HIV infected patients suffer from impaired neurocognitive function. The HIV protein transactivator of transcription (Tat) is an important contributor to HIV neuropathogenesis because it is a potent neurotoxin that continues to be produced despite treatment with antiretroviral therapy.

... Read more »

  • January 30, 2016
  • 07:01 AM
  • 654 views

The Automatic Neuroscientist

by Neuroskeptic in Neuroskeptic_Discover

We've learned this week that computers can play Go. But at least there's one human activity they will never master: neuroscience. A computer will never be a neuroscientist. Except... hang on. A new paper just out in Neuroimage describes something called The Automatic Neuroscientist. Oh.



So what is this new neuro-robot? According to its inventors, Romy Lorenz and colleagues of Imperial College London, it's a framework for using "real-time fMRI in combination with modern machine-learning te... Read more »

  • January 29, 2016
  • 08:36 AM
  • 698 views

Depression can easily pass down from a mother to her daughter

by Usman Paracha in SayPeople

Main Point:

Emotions can easily move down from mother to her daughter, i.e. daughters have more chances of getting from their mother a brain structure that is involved in emotion, especially depression.

Published in:

Journal of Neuroscience

Study Further:

Researchers from University of California – San Francisco (UCSF) studied the brains of 35 families by using magnetic resonance imaging (MRI). They found that the corticolimbic system, a structure of the brain circuitry, can........ Read more »

Yamagata, B., Murayama, K., Black, J., Hancock, R., Mimura, M., Yang, T., Reiss, A., & Hoeft, F. (2016) Female-Specific Intergenerational Transmission Patterns of the Human Corticolimbic Circuitry. Journal of Neuroscience, 36(4), 1254-1260. DOI: 10.1523/JNEUROSCI.4974-14.2016  

  • January 28, 2016
  • 02:36 PM
  • 607 views

It’s complicated: Benefits and toxicity of anti-prion antibodies in the brain

by Dr. Jekyll in Lunatic Laboratories

Immunotherapy to ameliorate neurodegeneration by targeting brain protein aggregates with antibodies is an area of intense investigation. A new study examines seemingly contradictory earlier results of targeting the prion protein and proposes a cautionary way forward to further test related therapeutic approaches.

... Read more »

Reimann, R., Sonati, T., Hornemann, S., Herrmann, U., Arand, M., Hawke, S., & Aguzzi, A. (2016) Differential Toxicity of Antibodies to the Prion Protein. PLOS Pathogens, 12(1). DOI: 10.1371/journal.ppat.1005401  

  • January 27, 2016
  • 02:36 PM
  • 758 views

The music of the mind: throwing light on human consciousness

by Dr. Jekyll in Lunatic Laboratories

UNSW Australia scientists have shown that complex human brain activity is governed by the same simple universal rule of nature that can explain other phenomena such as the beautiful sound of a finely crafted violin or the spots on a leopard. The UNSW team has identified a link between the distinctive patterns of brain function that occur at rest and the physical structure of people's brains.

... Read more »

  • January 27, 2016
  • 04:17 AM
  • 776 views

People with good brain have overall good health

by Usman Paracha in SayPeople

Main Point:

Intelligent people have a genetic ability to fight with most of the health-related problems.

Published in:

Molecular Psychiatry

Study Further:

Researchers from the University of Edinburgh have found that genes that are linked to thinking skills and intelligence are also linked to health. This shows that the intelligent people have less chances of becoming sick, getting disease, or die early.

In a new study, researchers worked on the participants of UK Biobank (havin........ Read more »

Hagenaars, S., Harris, S., Davies, G., Hill, W., Liewald, D., Ritchie, S., Marioni, R., Fawns-Ritchie, C., Cullen, B., Malik, R.... (2016) Shared genetic aetiology between cognitive functions and physical and mental health in UK Biobank (N. Molecular Psychiatry. DOI: 10.1038/mp.2015.225  

  • January 26, 2016
  • 03:20 PM
  • 613 views

Why you should never use the term ‘the mentally ill’

by Dr. Jekyll in Lunatic Laboratories

Even subtle differences in how you refer to people with mental illness can affect levels of tolerance, a new study has found. In a first-of-its-kind study, researchers found that participants showed less tolerance toward people who were referred to as "the mentally ill" when compared to those referred to as "people with mental illness."

... Read more »

  • January 24, 2016
  • 01:52 PM
  • 593 views

60 genetic disorders affect skin and nervous system

by Dr. Jekyll in Lunatic Laboratories

One of the most common genetic disorders is a condition called neurofibromatosis, which causes brown spots on the skin and benign tumors on the brain, spinal cord and other parts of the nervous system. Neurofibromatosis is one of at least 60 genetic diseases called neurocutaneous disorders that involve the skin, central nervous system, and/or peripheral nervous system.

... Read more »

Figueiredo, A., Mata-Machado, N., McCoyd, M., & Biller, J. (2016) Neurocutaneous Disorders for the Practicing Neurologist: a Focused Review. Current Neurology and Neuroscience Reports, 16(2). DOI: 10.1007/s11910-015-0612-7  

  • January 23, 2016
  • 02:26 PM
  • 645 views

When the music stops: Intensive instrument playing can lead to movement disorders

by Dr. Jekyll in Lunatic Laboratories

A musician takes up his/her violin and starts to play, but rather than gripping the strings, the fingers seize up--and this happens every time he/she takes up the instrument. Such a movement disorder--the so-called focal dystonia-- is a dramatic disease for those affected, which has thus far barely been studied.

... Read more »

Rozanski VE, Rehfuess E, Bötzel K, Nowak D. (2015) Task-specific dystonia in professional musicians—a systematic review of the importance of intensive playing as a risk factor. Dtsch Arztebl Int. info:/10.3238/arztebl.2015.0871

  • January 22, 2016
  • 02:50 PM
  • 612 views

Neurons in your gut help the immune system keep inflammation in check

by Dr. Jekyll in Lunatic Laboratories

The immune system exercises constant vigilance to protect the body from external threats–including what we eat and drink. A careful balancing act plays out as digested food travels through the intestine. Immune cells must remain alert to protect against harmful pathogens like Salmonella, but their activity also needs to be tempered since an overreaction can lead to too much inflammation and permanent tissue damage.

... Read more »

  • January 22, 2016
  • 08:30 AM
  • 845 views

This Neuroimaging Method Has 100% Diagnostic Accuracy (or your money back)

by The Neurocritic in The Neurocritic

doi:10.1371/journal.pone.0129659.g003Did you know that SPECT imaging can diagnose PTSD with 100% accuracy (Amen et al., 2015)? Not only that, out of a sample of 397 patients from the Amen Clinic in Newport Beach, SPECT was able to distinguish between four different groups with 100% accuracy! That's right, the scans of (1) healthy participants, and patients with (2) classic post-traumatic stress disorder (PTSD), (3) classic traumatic brain injury (TBI), and (4) both disorders..... were all classi........ Read more »

  • January 22, 2016
  • 12:13 AM
  • 646 views

Our brain can store information of the entire web (or more)

by Usman Paracha in SayPeople

Main Point:

Memory capacity of brain is about 10 times more than previous estimations, which is in the petabyte range, i.e. almost equivalent to the entire Web.

Published in:

eLife

Study Further:

Memories and thoughts in our brain are caused by a distinct pattern of chemical and electrical activity. Our brain has branches of neurons, which are connected to each other through synapses. Signals and information travel through these synapses with the help of neurotransmitters. Each ne........ Read more »

Bartol, T., Bromer, C., Kinney, J., Chirillo, M., Bourne, J., Harris, K., & Sejnowski, T. (2015) Nanoconnectomic upper bound on the variability of synaptic plasticity. eLife. DOI: 10.7554/eLife.10778  

  • January 21, 2016
  • 06:39 PM
  • 812 views

"Cat-gras Delusion" - The Man Who Saw His Cat As An Impostor

by Neuroskeptic in Neuroskeptic_Discover

Capgras syndrome is a strange disorder in which the sufferer becomes convinced that someone close to them has been replaced by an impostor.



Yet now, a new and even stranger variant of the syndrome has been reported - "Cat-gras". This is the name coined by Harvard neurologists R. Ryan Darby and David Caplan in a new paper in the journal Neurocase. The authors describe the case of a man who believed that his cat was in fact a different cat.



According to Darby and Caplan, the patient ... Read more »

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