A recent review article by Friedemann Pulvermuller looks at what is known about the neurobiology of language. He uses the question of what recent progress has been in the where, when, how and why of language processing in the brain. He does a masterful job and yet I am, personally, disappointed. In what way I [...]... Read more »
Friedemann Pulvermuller. (2010) Brain-Language Research: Where is the Progress. Biolinguistics, 4(2), 255-288. info:/
This Friday we are continuing coverage of the most recent IgNobel prizes, those awesome prizes given to celebrate the truly odd, yet wonderful findings in scientific research. Sci LOVES these prizes. In fact, someday I want to be invited, so I can LIVE BLOG these prizes. Interview the winners! Have hilarious conversations! YES! You should [...]... Read more »
I have previously posted a review of the brain imaging applications Brain Tutor and 3D Brain. My original review of the two applications for the iPhone and iPod Touch is located here and a review of the applications for the iPad are located here.The original iPad review noted that the iPad versions of both applications were essentially the iPhone version with the common 2x modification that essential doubles the size of the image to accommodate the larger screen with the iPad. There ........ Read more »
Estevez ME, Lindgren KA, & Bergethon PR. (2010) A novel three-dimensional tool for teaching human neuroanatomy. Anatomical sciences education. PMID: 20939033
Parents take note: if you want your kids to grow bigger brains, think twice about letting schools cut recess or skimp on physical education.
Animal and human studies have long shown that exercise increases neurogenesis, especially in memory- and learning-related areas of the brain. More recently, research on human adolescents has not only confirmed these findings, but highlighted the importance of physical activity for children.... Read more »
van Praag, H. (1999) Running enhances neurogenesis, learning, and long-term potentiation in mice. Proceedings of the National Academy of Sciences, 96(23), 13427-13431. DOI: 10.1073/pnas.96.23.13427
Praag, H. (2008) Neurogenesis and Exercise: Past and Future Directions. NeuroMolecular Medicine, 10(2), 128-140. DOI: 10.1007/s12017-008-8028-z
Chaddock, L., Erickson, K., Prakash, R., VanPatter, M., Voss, M., Pontifex, M., Raine, L., Hillman, C., & Kramer, A. (2010) Basal Ganglia Volume Is Associated with Aerobic Fitness in Preadolescent Children. Developmental Neuroscience, 32(3), 249-256. DOI: 10.1159/000316648
Chaddock, L., Erickson, K., Prakash, R., Kim, J., Voss, M., VanPatter, M., Pontifex, M., Raine, L., Konkel, A., & Hillman, C. (2010) A neuroimaging investigation of the association between aerobic fitness, hippocampal volume, and memory performance in preadolescent children. Brain Research, 172-183. DOI: 10.1016/j.brainres.2010.08.049
Åberg, E., Hofstetter, C., Olson, L., & Brené, S. (2005) Moderate ethanol consumption increases hippocampal cell proliferation and neurogenesis in the adult mouse. The International Journal of Neuropsychopharmacology, 8(04), 557. DOI: 10.1017/S1461145705005286
van Praag, H., Lucero, M., Yeo, G., Stecker, K., Heivand, N., Zhao, C., Yip, E., Afanador, M., Schroeter, H., Hammerstone, J.... (2007) Plant-Derived Flavanol (-)Epicatechin Enhances Angiogenesis and Retention of Spatial Memory in Mice. Journal of Neuroscience, 27(22), 5869-5878. DOI: 10.1523/JNEUROSCI.0914-07.2007
Jiang, W. (2005) Cannabinoids promote embryonic and adult hippocampus neurogenesis and produce anxiolytic- and antidepressant-like effects. Journal of Clinical Investigation, 115(11), 3104-3116. DOI: 10.1172/JCI25509
DOWNER, E., & CAMPBELL, V. (2009) Phytocannabinoids, CNS cells and development: A dead issue?. Drug and Alcohol Review, 29(1), 91-98. DOI: 10.1111/j.1465-3362.2009.00102.x
Nature Reviews Neuroscience is a scientific journal dedicated to neuroscience topics that recently celebrated it’s ten year anniversary. To commemorate the accomplishment, the most highly cited articles from each of the last 10 years was identified. This method provides a good proxy for the most important publication each year. The 2009 most cited article was Dr. A.D. Craig’s article entitled: “How do you feel—now? The anterior insula and human awareness”.Dr. Craig’........ Read more »
Craig AD. (2009) How do you feel--now? The anterior insula and human awareness. Nature reviews. Neuroscience, 10(1), 59-70. PMID: 19096369
Luo L, Rodriguez E, Jerbi K, Lachaux JP, Martinerie J, Corbetta M, Shulman GL, Piomelli D, Turrigiano GG, Nelson SB.... (2010) Ten years of Nature Reviews Neuroscience: insights from the highly cited. Nature reviews. Neuroscience, 11(10), 718-26. PMID: 20852655
i *love* good coffee. You? Do you know how you react to coffee? Do you find caffeine keeps you awake/alert? Yes? or maybe you find it doesn't affect your getting to sleep? We know that the magic in coffee is caffeine. Guess what? apparently whether or not we can fall asleep with caffeine is less of an issue than what it does to our sleep quality, in particular, our deep sleep state. That is, it ... Read more »
Gore RK, Webb TS, & Hermes ED. (2010) Fatigue and stimulant use in military fighter aircrew during combat operations. Aviation, space, and environmental medicine, 81(8), 719-27. PMID: 20681231
Ferré S. (2010) Role of the central ascending neurotransmitter systems in the psychostimulant effects of caffeine. Journal of Alzheimer's disease : JAD. PMID: 20182056
Yang, A., Palmer, A., & Wit, H. (2010) Genetics of caffeine consumption and responses to caffeine. Psychopharmacology, 211(3), 245-257. DOI: 10.1007/s00213-010-1900-1
A recently published study in PNAS explores how small babies relate order and disorder, or entropy, to the different types of things that may cause them. Amazingly, babies as small as 12 months old show some understanding of the difference between the deliberate and goal-directed "agents" that can cause order, such as a person, and those randomly acting inanimate objects that cannot, such as a bouncing ball. This means that we have some sort of general understanding that the way agents act on t........ Read more »
Newman, G., Keil, F., Kuhlmeier, V., & Wynn, K. (2010) Early understandings of the link between agents and order. Proceedings of the National Academy of Sciences, 107(40), 17140-17145. DOI: 10.1073/pnas.0914056107
Two recent papers have provided strong evidence that the brain's endocannabinoid system is dysfunctional in Huntington's Disease, paving the way to possible new treatments.Huntington's Disease is a genetic neurological disorder. Symptoms generally appear around age 40, and progress gradually from subtle movement abnormalities to dementia and complete loss of motor control. It's incurable, although medication can mask some of the symptoms. Singer Woodie Guthrie is perhaps the disease's best known........ Read more »
Van Laere K, Casteels C, Dhollander I, Goffin K, Grachev I, Bormans G, & Vandenberghe W. (2010) Widespread decrease of type 1 cannabinoid receptor availability in Huntington disease in vivo. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 51(9), 1413-7. PMID: 20720046
Blázquez C, Chiarlone A, Sagredo O, Aguado T, Pazos MR, Resel E, Palazuelos J, Julien B, Salazar M, Börner C.... (2010) Loss of striatal type 1 cannabinoid receptors is a key pathogenic factor in Huntington's disease. Brain : a journal of neurology. PMID: 20929960
So Sci was sitting in a seminar the other day. We were mentioning this paper, some problems we had with it, some of the things we LIKED about it, and various approaches, etc, in our usual sciencey fashion. As the discussion got intense (in a good way), one of the PIs there leaned over and [...]... Read more »
LaPlant Q, Vialou V, Covington HE 3rd, Dumitriu D, Feng J, Warren BL, Maze I, Dietz DM, Watts EL, Iñiguez SD.... (2010) Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens. Nature neuroscience, 13(9), 1137-43. PMID: 20729844
Ever been asked--if you had to choose, would you rather be deaf or blind? Its a futile hypothetical dilemma (as if the choice is ever available to anyone to make) that was probably first posed by some perpetually dramatic and irrevocably bored teenager OR--could it be--by a neuroscientist!
Perhaps we cherry pick vision and hearing for our speculative crises because they are particularly important to us and essential to achieve something our species is known for: high level mobility and naviga........ Read more »
Lomber SG, Meredith MA, & Kral A. (2010) Cross-modal plasticity in specific auditory cortices underlies visual compensations in the deaf. Nature neuroscience. PMID: 20935644
Poulos AM, Ponnusamy R, Dong HW, & Fanselow MS. (2010) Compensation in the neural circuitry of fear conditioning awakens learning circuits in the bed nuclei of the stria terminalis. Proceedings of the National Academy of Sciences of the United States of America, 107(33), 14881-6. PMID: 20679237
There is very limited research to guideline clinicians, patients and their family members in choosing the best treatments for anorexia nervosa and other eating disorders. So when a well-designed and informative study is published it is noteworthy and important to review. James Lock and colleagues summarized their findings from a randomized trial of family therapy versus individual therapy in a randomized controlled trial for adolescents with anorexia nervosa in the October 2010........ Read more »
Lock J, Le Grange D, Agras WS, Moye A, Bryson SW, & Jo B. (2010) Randomized clinical trial comparing family-based treatment with adolescent-focused individual therapy for adolescents with anorexia nervosa. Archives of general psychiatry, 67(10), 1025-32. PMID: 20921118
On September 30, the Marian Koshland Science Museum in Washington, DC, held an interactive lecture which posed the question: “Can you train your neural pathways to stay active and strong ... Read more »
Hertzog, C., Kramer, A., Wilson, R., & Lindenberger, U. (2008) Enrichment Effects on Adult Cognitive Development: Can the Functional Capacity of Older Adults Be Preserved and Enhanced?. Psychological Science in the Public Interest. DOI: 10.1111/j.1539-6053.2009.01034.x
Are people with autism susceptible to magical illusions? There are a number of reasons to suspect that they might not be.Firstly, magicians rely on misdirection. They'll use eye gaze and gesture to make sure the audience is looking one way, while they're secretly switching the cards or sneaking an elephant into a hat (or whatever it is they do). People with autism, it's argued, are less sensitive to these kinds of social cues, so perhaps they're not as easily misdirected.Second, as mentioned in........ Read more »
I describe a new paper that looks at spine density and cognitive function in the brains of postpartum female rats.... Read more »
Leuner B, & Gould E. (2010) Dendritic Growth in Medial Prefrontal Cortex and Cognitive Flexibility Are Enhanced during the Postpartum Period. The Journal of neuroscience : the official journal of the Society for Neuroscience, 30(40), 13499-503. PMID: 20926675
Having written a number of posts on acupuncture (see here, here, and here) I guess my particular biases are reasonably apparent. So imagine my surprise when a large RCT published in the journal “Pain” reports a significant and substantial effect of Chinese acupuncture in comparison with sham acupuncture or conventional orthopaedic therapy for chronic shoulder [...]... Read more »
Molsberger AF, Schneider T, Gotthardt H, & Drabik A. (2010) German Randomized Acupuncture Trial for chronic shoulder pain (GRASP) - a pragmatic, controlled, patient-blinded, multi-centre trial in an outpatient care environment. Pain, 151(1), 146-54. PMID: 20655660
O'Connell NE, Wand BM, & Goldacre B. (2009) Interpretive bias in acupuncture research?: A case study. Evaluation , 32(4), 393-409. PMID: 19942631
Linde K, Witt CM, Streng A, Weidenhammer W, Wagenpfeil S, Brinkhaus B, Willich SN, & Melchart D. (2007) The impact of patient expectations on outcomes in four randomized controlled trials of acupuncture in patients with chronic pain. Pain, 128(3), 264-71. PMID: 17257756
I have liked Friston’s ideas for some time, so what a shock it is to find him defending Freudian ideas. Naïve me, I thought that Freud’s model was dead in the water. Why? It is untested, does not fit with current evidence and, further, is probably untestable therefore not good science. It fails the Occam’s [...]... Read more »
Carhart-Harris, R., & Friston, K. (2010) The default-mode, ego-functions and free-energy: a neurobiological account of Freudian ideas. Brain, 133(4), 1265-1283. DOI: 10.1093/brain/awq010
Virtual cataract surgery is a customized optical modeling helping the design of intraocular lenses and improving vision of cataract patients... learn more... Read more »
Tabernero, J. et al. (2006) Predicting the Optical Performance of Eyes Implanted with IOLs to Correct Spherical Aberration. Investigative Ophthalmology , 47(10), 4651-4658. DOI: 10.1167/iovs.06-0444
This paper in the current issue of the journal Neuron claims to add some MRI findings to the evidence that human empathy and kindness stop at the border between "our group" and "others." Tania Singer, Grit Hein and their colleagues found that Swiss soccer fans feel more, and do more, about the suffering of fellow fans than they do for supporters of a rival team.
The researchers recruited 16 Zurich men from a local fan club, telling them they would be involved in a comparison of brain ........ Read more »
Hein, G., Silani, G., Preuschoff, K., Batson, C., & Singer, T. (2010) Neural Responses to Ingroup and Outgroup Members' Suffering Predict Individual Differences in Costly Helping. Neuron, 68(1), 149-160. DOI: 10.1016/j.neuron.2010.09.003
Xu, X., Zuo, X., Wang, X., & Han, S. (2009) Do You Feel My Pain? Racial Group Membership Modulates Empathic Neural Responses. Journal of Neuroscience, 29(26), 8525-8529. DOI: 10.1523/JNEUROSCI.2418-09.2009
Gutsell, J., & Inzlicht, M. (2010) Empathy constrained: Prejudice predicts reduced mental simulation of actions during observation of outgroups. Journal of Experimental Social Psychology. DOI: 10.1016/j.jesp.2010.03.011
Singer, T., Seymour, B., O'Doherty, J., Stephan, K., Dolan, R., & Frith, C. (2006) Empathic neural responses are modulated by the perceived fairness of others. Nature, 439(7075), 466-469. DOI: 10.1038/nature04271
To evolutionary psychologists, the noise made by gorillas, chimps and bonobos when you tickle their feet is no laughing matter. These distinctive vocalisations suggest that rather than evolving separately, laughter evolved in a shared common ancestor before becoming tailored in each primate species, including humans.
To find support for this idea, Diana Szameitat and her colleagues scanned the brains of 18 men and women whilst they listened to the sound of human tickle-induced laughter as well ........ Read more »
Szameitat, D., Kreifelts, B., Alter, K., Szameitat, A., Sterr, A., Grodd, W., & Wildgruber, D. (2010) It is not always tickling: Distinct cerebral responses during perception of different laughter types. NeuroImage, 53(4), 1264-1271. DOI: 10.1016/j.neuroimage.2010.06.028
As a general rule, the cells of your body ought only grow, survive and proliferate when so directed by upstream messages, hormonal or otherwise. In light of the supreme importance of proper and well-timed growth, it is these messaging systems that have recently become the stars of the show. One area of particular importance is [...]... Read more »
Cordeira, J., Frank, L., Sena-Esteves, M., Pothos, E., & Rios, M. (2010) Brain-Derived Neurotrophic Factor Regulates Hedonic Feeding by Acting on the Mesolimbic Dopamine System. Journal of Neuroscience, 30(7), 2533-2541. DOI: 10.1523/JNEUROSCI.5768-09.2010
Do you write about peer-reviewed research in your blog? Use ResearchBlogging.org to make it easy for your readers — and others from around the world — to find your serious posts about academic research.
If you don't have a blog, you can still use our site to learn about fascinating developments in cutting-edge research from around the world.
Research Blogging is powered by SMG Technology.
To learn more, visit seedmediagroup.com.