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  • June 2, 2011
  • 06:26 PM

Religious Factors & hippocampal atrophy or hypertrophy?

by Kausik Datta in In Scientio Veritas

As a testament to humankind's everlasting quest for knowledge and understanding of the self, a number of scientific studies in the recent times have examined the elusive relationship between the human brain and that fountainhead of human emotion and...... Read more »

  • June 2, 2011
  • 09:30 AM

Giving him the (fake) finger. Introducing the plastic finger illusion.

by Lorimer Moseley in BodyInMind

Does proprioceptive input, from muscle spindles and joint receptors for example, contribute to our sense of body ownership?... Read more »

[1] Botvinick M, & Cohen J. (1998) Rubber hands 'feel' touch that eyes see. Nature, 391(6669), 756. PMID: 9486643  

[2] Walsh LD, Moseley GL, Taylor JL, & Gandevia SC. (2011) Proprioceptive signals contribute to the sense of body ownership. The Journal of physiology. PMID: 21521765  

  • June 2, 2011
  • 09:03 AM

Bupropion Fails to Aid Hospitalized Smokers with Heart Disease

by William Yates, M.D. in Brain Posts

Smoking and nicotine dependence increase rates for heart disease in the general population. Among those with heart disease, continued smoking increases mortality rates. Targeting smoking cessation efforts at those with heart disease (secondary prevention)is an important clinical challenge.  Most of the research data related to drugs for smoking cessation come from subjects recruited from the general population. Both bupropion (Zyban)and varenicline (Chantix)are FDA-approved drugs for smokin........ Read more »

Planer, D., Lev, I., Elitzur, Y., Sharon, N., Ouzan, E., Pugatsch, T., Chasid, M., Rom, M., & Lotan, C. (2011) Bupropion for Smoking Cessation in Patients With Acute Coronary Syndrome. Archives of Internal Medicine. DOI: 10.1001/archinternmed.2011.72  

  • June 2, 2011
  • 04:21 AM

The Holographic Brain

by Neuroskeptic in Neuroskeptic

According to the holonomic brain theory,Cognitive function is guided by a matrix of neurological wave interference patterns situated temporally between holographic Gestalt perception and discrete, affective, quantum vectors derived from reward anticipation potentials.Well, I don't know about that, but a group of neuroscientists have just reported on using holograms as a tool for studying brain function: Three-dimensional holographic photostimulation of the dendritic arbor.A while ago, scientists........ Read more »

Yang S, Papagiakoumou E, Guillon M, de Sars V, Tang CM, & Emiliani V. (2011) Three-dimensional holographic photostimulation of the dendritic arbor. Journal of neural engineering, 8(4), 46002. PMID: 21623008  

  • June 1, 2011
  • 08:51 AM

Fiber Up! Dietary Fiber and Mortality Risk

by William Yates, M.D. in Brain Posts

We hear quite a bit in the lay press about the potential benefits of dietary fiber including eating multiple daily servings whole grains,  fruits and vegetables.  I tend to be skeptical of many of these recommendations.  But after following some of the research related to the Mediterranean Diet,  I at least have my antenna (and my Google Reader) up on this issue.  The Google Reader recently retrieved an online first article from the Archives of Internal Medicine by Dr. P........ Read more »

  • May 31, 2011
  • 04:14 PM

Vaccines Cause Autism, Until You Look At The Data

by Neuroskeptic in Neuroskeptic

According to a much-discussed new paper, vaccines may cause autism after all: A Positive Association found between Autism Prevalence and Childhood Vaccination uptake across the U.S. Population.The author is Gayle DeLong, who "teaches international finance at Baruch College, City University of New York", according to her profile as a board member of anti-vaccine group SafeMinds. She correlated rates of coverage of the government recommended full set of vaccines in the 51 US states including Washi........ Read more »

  • May 31, 2011
  • 07:49 AM

Brief Behavioral Therapy for Insomnia in Older Adults

by William Yates, M.D. in Brain Posts

Insomnia is a common complaint in the general population and among patients treated by primary care physicians.  This is particularly true for older adults who experience physiological changes in sleep with aging.  Clinicians commonly prescribe hypnotics for insomnia and the use of these types of drugs is increasing in the United States and elsewhere.  Behavioral and psychological interventions may be overlooked or bypassed in the sequencing of interventions for complaints of inso........ Read more »

Buysse, D., Germain, A., Moul, D., Franzen, P., Brar, L., Fletcher, M., Begley, A., Houck, P., Mazumdar, S., Reynolds, C.... (2011) Efficacy of Brief Behavioral Treatment for Chronic Insomnia in Older Adults. Archives of Internal Medicine, 171(10), 887-895. DOI: 10.1001/archinternmed.2010.535  

  • May 31, 2011
  • 02:30 AM

The cortical body matrix. Reloaded.

by Lorimer Moseley in BodyInMind

People with chronic pain have some pretty odd perceptual disturbances. In an attempt to integrate this smorgasboard of body-related dysfunction, we recently proposed the idea of a cortical body matrix.... Read more »

  • May 30, 2011
  • 07:09 PM

Study Demonstrates False Memories Implanted Via Advertising

by Neurobonkers in Neurobonkers

A study builds false memories of experience tasting popcorn using advertising. Methodology, questionable.... Read more »

Rajagopal, Priyali and Montgomery, Nicole Votolato,. (2011) I Imagine I Experience, I Like: The False Experience Effect . The Journal of Consumer Research. info:/

  • May 30, 2011
  • 08:00 AM

How my ethics of brain scanning paper was overtaken by events

by Zen Faulkes in NeuroDojo

I know my most recent paper is probably going take some flak as being naïve.

This is the price you pay for trying to expand your horizons. An invert neuro guy writing an ethics paper? About brain scans? In humans? With spies? The potential to look foolish is huge.

But since I’ve gone and done it anyway, let me tell you how it all came about.

This paper started about three years when I ran into my colleague Cynthia Jones at lunch at the student union. I actually hadn’t seen her for a whil........ Read more »

Faulkes Z. (2011) Can brain imaging replace interrogation and torture?. Global Virtue Ethics Review, 6(2), 55-78. info:/

  • May 27, 2011
  • 02:06 PM

Advances in Treatment of Tinnitus (Ear Ringing)

by William Yates, M.D. in Brain Posts

Tinnitus is a common neurological condition affecting up to 10% or more of elderly individuals.  Variable it severity, in it's most serious form it can be disabling and quite distressful.  Due to the chronic nature of the disorder, many patients with tinnitus develop depression.  Suicide rates have been estimated to be increased in those with tinnitus-related.  Althought the exact cause is unknown for tinnitus, abnormalities in spontaneous neural activity in the auditory brai........ Read more »

Piccirillo JF, Garcia KS, Nicklaus J, Pierce K, Burton H, Vlassenko AG, Mintun M, Duddy D, Kallogjeri D, & Spitznagel EL Jr. (2011) Low-frequency repetitive transcranial magnetic stimulation to the temporoparietal junction for tinnitus. Archives of otolaryngology--head , 137(3), 221-8. PMID: 21422304  

  • May 27, 2011
  • 11:45 AM

Autistic Brains 'Genes Differ'

by Neuroskeptic in Neuroskeptic

The BBC say:The brains of people with autism are chemically different to those without autism, according to researchers. A study, published in the journal Nature, showed the unique characters of the frontal and temporal lobes had disappeared.It's not a bad summary, although it doesn't explain quite how interesting the new results are. Here's the paper, from a joint US/British team: Transcriptomic analysis of autistic brain reveals convergent molecular pathologyThe authors took 19 brains from peo........ Read more »

Voineagu I, Wang X, Johnston P, Lowe JK, Tian Y, Horvath S, Mill J, Cantor RM, Blencowe BJ, & Geschwind DH. (2011) Transcriptomic analysis of autistic brain reveals convergent molecular pathology. Nature. PMID: 21614001  

  • May 27, 2011
  • 08:00 AM

Sexy eyes? Estrogen in the visual system

by Zen Faulkes in NeuroDojo

Neurotransmitters get all the glory as the most interesting molecules in the nervous system. They are responsible for the fast signalling between two neurons; things that are all over in a few milliseconds.

But the nervous system is awash in chemicals, which influence neurons in many ways. Hormones, for instance, influence behaviour by acting on nervous systems.

It’s a little unusual, though, to think of brains making their own hormones. Oh, sure, the pituitary gland sits right next to brai........ Read more »

  • May 27, 2011
  • 03:30 AM

Friday Weird Science: Is that a Cell Phone in your Pocket or are you just happy to see me?

by Scicurious in Neurotic Physiology

Ever since doing a couple of pieces of cell phones and things like sperm, I've become curious about what other studies have been done on the effects of cell phone use and keeping a small, highly addictive electronic object on your person (even though, sometimes, I end up very wrong). Not surprisingly, there's a large [...]... Read more »

Rothberg, M., Arora, A., Hermann, J., Kleppel, R., Marie, P., & Visintainer, P. (2010) Phantom vibration syndrome among medical staff: a cross sectional survey. BMJ, 341(dec15 2). DOI: 10.1136/bmj.c6914  

  • May 26, 2011
  • 07:25 PM

Nicotine alters glutamatergic input to VTA neurons through alpha 7 receptors

by Tantalus Prime in Tantalus Prime

When it comes to drugs of abuse it seems that all roads lead to the VTA. What local streets those drugs take when they get there is another matter. For example, the dopaminergic activating effects of psychostimulants are modulated by glutamate release in the VTA in a D1-like DA receptor manner. What about other drugs like nicotine? Turns out glutamatergic output is also D1 dependent in this case. But the VTA has a whole bunch of nicotinic receptors, mainly of two varieties. Alpha4beta6, which ar........ Read more »

  • May 26, 2011
  • 09:51 AM

Crossing the blood brain barrier with drug development

by Sally Church in Pharma Strategy Blog

The beauty of social media is that sometimes someone shares something monumental before you even pick it up yourself in a journal you’re subscribed to. I love that – it’s a great way to see how others find things with … Continue reading →
... Read more »

Atwal, J., Chen, Y., Chiu, C., Mortensen, D., Meilandt, W., Liu, Y., Heise, C., Hoyte, K., Luk, W., Lu, Y.... (2011) A Therapeutic Antibody Targeting BACE1 Inhibits Amyloid-  Production in Vivo. Science Translational Medicine, 3(84), 84-84. DOI: 10.1126/scitranslmed.3002254  

  • May 26, 2011
  • 09:00 AM

The Alice Illusion – scientists convince people that they’re dolls or giants

by Ed Yong in Not Exactly Rocket Science

In Alice’s Adventures in Wonderland, the titular heroine quaffs a potion that shrinks her down to the size of a doll, and eats a cake that makes her grow to gigantic proportions. Such magic doesn’t exist outside of Lewis Carroll’s imagination, but there are certainly ways of making people think that they have changed in size.
There’s nowhere in the world that’s better at creating such illusions than the lab of Henrik Ehrsson in Sweden’s Karolinska Institute. In a typical experiment, ........ Read more »

  • May 26, 2011
  • 02:10 AM

Don’t just rub it better, cross it over – the analgesic effect of crossing your arms.

by Lorimer Moseley in BodyInMind

There is a new paper just out in Pain that raises the possibility of a quick and easy analgesic strategy – crossing your arms. My mum reckons that her mum was onto that decades ago ... Read more »

[1]Gallace A, Torta DM, Moseley GL, & Iannetti GD. (2011) The analgesic effect of crossing the arms. Pain, 152(6), 1418-23. PMID: 21440992  

  • May 25, 2011
  • 10:35 PM

Canadian College of Neuropsychopharmacology conference 2011

by davejhayes in neurosphere

The Canadian College of Neuropsychopharmacology (CCNP) is the premier college in Canada for expert knowledge on the pharmacology of brain function. This year’s conference was held in la belle ville de Montréal.... Read more »

  • May 25, 2011
  • 10:04 AM

Attention Training in ADHD

by William Yates, M.D. in Brain Posts

The relative merits of medication versus behavioral treatment of ADHD continues to be an focus of concern for parents and researchers.  It has been nearly 12 years since the publication of the classic study titled: Multimodal Treatment Study of Children with ADHD (MTA).  This study compared children with ADHD assigned randomly to one of four treatment arms:stimulant drug treatment alone (titrated to response),intensive behavioral treatment alone, combined stimulant and behavioral ........ Read more »

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