As a testament to humankind's everlasting quest for knowledge and understanding of the self, a number of scientific studies in the recent times have examined the elusive relationship between the human brain and that fountainhead of human emotion and...... Read more »
Owen AD, Hayward RD, Koenig HG, Steffens DC, & Payne ME. (2011) Religious Factors and Hippocampal Atrophy in Late Life. PLoS One. DOI: 10.1371/journal.pone.0017006
Does proprioceptive input, from muscle spindles and joint receptors for example, contribute to our sense of body ownership?... Read more »
 Walsh LD, Moseley GL, Taylor JL, & Gandevia SC. (2011) Proprioceptive signals contribute to the sense of body ownership. The Journal of physiology. PMID: 21521765
Smoking and nicotine dependence increase rates for heart disease in the general population. Among those with heart disease, continued smoking increases mortality rates. Targeting smoking cessation efforts at those with heart disease (secondary prevention)is an important clinical challenge. Most of the research data related to drugs for smoking cessation come from subjects recruited from the general population. Both bupropion (Zyban)and varenicline (Chantix)are FDA-approved drugs for smokin........ Read more »
Planer, D., Lev, I., Elitzur, Y., Sharon, N., Ouzan, E., Pugatsch, T., Chasid, M., Rom, M., & Lotan, C. (2011) Bupropion for Smoking Cessation in Patients With Acute Coronary Syndrome. Archives of Internal Medicine. DOI: 10.1001/archinternmed.2011.72
According to the holonomic brain theory,Cognitive function is guided by a matrix of neurological wave interference patterns situated temporally between holographic Gestalt perception and discrete, affective, quantum vectors derived from reward anticipation potentials.Well, I don't know about that, but a group of neuroscientists have just reported on using holograms as a tool for studying brain function: Three-dimensional holographic photostimulation of the dendritic arbor.A while ago, scientists........ Read more »
Yang S, Papagiakoumou E, Guillon M, de Sars V, Tang CM, & Emiliani V. (2011) Three-dimensional holographic photostimulation of the dendritic arbor. Journal of neural engineering, 8(4), 46002. PMID: 21623008
We hear quite a bit in the lay press about the potential benefits of dietary fiber including eating multiple daily servings whole grains, fruits and vegetables. I tend to be skeptical of many of these recommendations. But after following some of the research related to the Mediterranean Diet, I at least have my antenna (and my Google Reader) up on this issue. The Google Reader recently retrieved an online first article from the Archives of Internal Medicine by Dr. P........ Read more »
Park, Y., Subar, A., Hollenbeck, A., & Schatzkin, A. (2011) Dietary Fiber Intake and Mortality in the NIH-AARP Diet and Health Study. Archives of Internal Medicine. DOI: 10.1001/archinternmed.2011.18
According to a much-discussed new paper, vaccines may cause autism after all: A Positive Association found between Autism Prevalence and Childhood Vaccination uptake across the U.S. Population.The author is Gayle DeLong, who "teaches international finance at Baruch College, City University of New York", according to her profile as a board member of anti-vaccine group SafeMinds. She correlated rates of coverage of the government recommended full set of vaccines in the 51 US states including Washi........ Read more »
Delong G. (2011) A Positive Association found between Autism Prevalence and Childhood Vaccination uptake across the U.S. Population. Journal of toxicology and environmental health. Part A, 74(14), 903-16. PMID: 21623535
Insomnia is a common complaint in the general population and among patients treated by primary care physicians. This is particularly true for older adults who experience physiological changes in sleep with aging. Clinicians commonly prescribe hypnotics for insomnia and the use of these types of drugs is increasing in the United States and elsewhere. Behavioral and psychological interventions may be overlooked or bypassed in the sequencing of interventions for complaints of inso........ Read more »
Buysse, D., Germain, A., Moul, D., Franzen, P., Brar, L., Fletcher, M., Begley, A., Houck, P., Mazumdar, S., Reynolds, C.... (2011) Efficacy of Brief Behavioral Treatment for Chronic Insomnia in Older Adults. Archives of Internal Medicine, 171(10), 887-895. DOI: 10.1001/archinternmed.2010.535
People with chronic pain have some pretty odd perceptual disturbances. In an attempt to integrate this smorgasboard of body-related dysfunction, we recently proposed the idea of a cortical body matrix.... Read more »
 Moseley, G. (2005) Distorted body image in complex regional pain syndrome. Neurology, 65(5), 773-773. DOI: 10.1212/01.wnl.0000174515.07205.11
 Moseley GL. (2008) I can't find it! Distorted body image and tactile dysfunction in patients with chronic back pain. Pain, 140(1), 239-43. PMID: 18786763
 Moseley GL, Gallace A, & Spence C. (2011) Bodily illusions in health and disease: Physiological and clinical perspectives and the concept of a cortical 'body matrix'. Neuroscience and biobehavioral reviews. PMID: 21477616
 Moseley, G., Parsons, T., & Spence, C. (2008) Visual distortion of a limb modulates the pain and swelling evoked by movement. Current Biology, 18(22). DOI: 10.1016/j.cub.2008.09.031
A study builds false memories of experience tasting popcorn using advertising. Methodology, questionable.... Read more »
Rajagopal, Priyali and Montgomery, Nicole Votolato,. (2011) I Imagine I Experience, I Like: The False Experience Effect . The Journal of Consumer Research. info:/
I know my most recent paper is probably going take some flak as being naïve.
This is the price you pay for trying to expand your horizons. An invert neuro guy writing an ethics paper? About brain scans? In humans? With spies? The potential to look foolish is huge.
But since I’ve gone and done it anyway, let me tell you how it all came about.
This paper started about three years when I ran into my colleague Cynthia Jones at lunch at the student union. I actually hadn’t seen her for a whil........ Read more »
Faulkes Z. (2011) Can brain imaging replace interrogation and torture?. Global Virtue Ethics Review, 6(2), 55-78. info:/
Ganis G, Rosenfeld J, Meixner J, Kievit R, & Schendan H. (2011) Lying in the scanner: Covert countermeasures disrupt deception detection by functional magnetic resonance imaging. NeuroImage, 55(1), 312-319. DOI: 10.1016/j.neuroimage.2010.11.025
Rissman J, Greely H, & Wagner A. (2010) Detecting individual memories through the neural decoding of memory states and past experience. Proceedings of the National Academy of Sciences, 107(21), 9849-9854. DOI: 10.1073/pnas.1001028107
Shirer, W., Ryali, S., Rykhlevskaia, E., Menon, V., & Greicius, M. (2011) Decoding Subject-Driven Cognitive States with Whole-Brain Connectivity Patterns. Cerebral Cortex. DOI: 10.1093/cercor/bhr099
Slotnick S, & Schacter D. (2004) A sensory signature that distinguishes true from false memories. Nature Neuroscience, 7(6), 664-672. DOI: 10.1038/nn1252
Tinnitus is a common neurological condition affecting up to 10% or more of elderly individuals. Variable it severity, in it's most serious form it can be disabling and quite distressful. Due to the chronic nature of the disorder, many patients with tinnitus develop depression. Suicide rates have been estimated to be increased in those with tinnitus-related. Althought the exact cause is unknown for tinnitus, abnormalities in spontaneous neural activity in the auditory brai........ Read more »
Piccirillo JF, Garcia KS, Nicklaus J, Pierce K, Burton H, Vlassenko AG, Mintun M, Duddy D, Kallogjeri D, & Spitznagel EL Jr. (2011) Low-frequency repetitive transcranial magnetic stimulation to the temporoparietal junction for tinnitus. Archives of otolaryngology--head , 137(3), 221-8. PMID: 21422304
Parazzini M, Del Bo L, Jastreboff M, Tognola G, & Ravazzani P. (2011) Open ear hearing aids in tinnitus therapy: An efficacy comparison with sound generators. International journal of audiology. PMID: 21595527
The BBC say:The brains of people with autism are chemically different to those without autism, according to researchers. A study, published in the journal Nature, showed the unique characters of the frontal and temporal lobes had disappeared.It's not a bad summary, although it doesn't explain quite how interesting the new results are. Here's the paper, from a joint US/British team: Transcriptomic analysis of autistic brain reveals convergent molecular pathologyThe authors took 19 brains from peo........ Read more »
Voineagu I, Wang X, Johnston P, Lowe JK, Tian Y, Horvath S, Mill J, Cantor RM, Blencowe BJ, & Geschwind DH. (2011) Transcriptomic analysis of autistic brain reveals convergent molecular pathology. Nature. PMID: 21614001
Neurotransmitters get all the glory as the most interesting molecules in the nervous system. They are responsible for the fast signalling between two neurons; things that are all over in a few milliseconds.
But the nervous system is awash in chemicals, which influence neurons in many ways. Hormones, for instance, influence behaviour by acting on nervous systems.
It’s a little unusual, though, to think of brains making their own hormones. Oh, sure, the pituitary gland sits right next to brai........ Read more »
Jeong J, Tremere L, Burrows K, Majewska A, & Pinaud R. (2011) The mouse primary visual cortex is a site of production and sensitivity to estrogens. PLoS ONE, 6(5). DOI: 10.1371/journal.pone.0020400
Ever since doing a couple of pieces of cell phones and things like sperm, I've become curious about what other studies have been done on the effects of cell phone use and keeping a small, highly addictive electronic object on your person (even though, sometimes, I end up very wrong). Not surprisingly, there's a large [...]... Read more »
Rothberg, M., Arora, A., Hermann, J., Kleppel, R., Marie, P., & Visintainer, P. (2010) Phantom vibration syndrome among medical staff: a cross sectional survey. BMJ, 341(dec15 2). DOI: 10.1136/bmj.c6914
When it comes to drugs of abuse it seems that all roads lead to the VTA. What local streets those drugs take when they get there is another matter. For example, the dopaminergic activating effects of psychostimulants are modulated by glutamate release in the VTA in a D1-like DA receptor manner. What about other drugs like nicotine? Turns out glutamatergic output is also D1 dependent in this case. But the VTA has a whole bunch of nicotinic receptors, mainly of two varieties. Alpha4beta6, which ar........ Read more »
Jin Y, Yang K, Wang H, & Wu J. (2011) Exposure of nicotine to ventral tegmental area slices induces glutamatergic synaptic plasticity on dopamine neurons. Synapse (New York, N.Y.), 65(4), 332-8. PMID: 20730803
The beauty of social media is that sometimes someone shares something monumental before you even pick it up yourself in a journal you’re subscribed to. I love that – it’s a great way to see how others find things with … Continue reading →
... Read more »
Atwal, J., Chen, Y., Chiu, C., Mortensen, D., Meilandt, W., Liu, Y., Heise, C., Hoyte, K., Luk, W., Lu, Y.... (2011) A Therapeutic Antibody Targeting BACE1 Inhibits Amyloid- Production in Vivo. Science Translational Medicine, 3(84), 84-84. DOI: 10.1126/scitranslmed.3002254
In Alice’s Adventures in Wonderland, the titular heroine quaffs a potion that shrinks her down to the size of a doll, and eats a cake that makes her grow to gigantic proportions. Such magic doesn’t exist outside of Lewis Carroll’s imagination, but there are certainly ways of making people think that they have changed in size.
There’s nowhere in the world that’s better at creating such illusions than the lab of Henrik Ehrsson in Sweden’s Karolinska Institute. In a typical experiment, ........ Read more »
van der Hoort, B., Guterstam, A., & Ehrsson, H. (2011) Being Barbie: The Size of One’s Own Body Determines the Perceived Size of the World. PLoS ONE, 6(5). DOI: 10.1371/journal.pone.0020195
There is a new paper just out in Pain that raises the possibility of a quick and easy analgesic strategy – crossing your arms. My mum reckons that her mum was onto that decades ago ... Read more »
The Canadian College of Neuropsychopharmacology (CCNP) is the premier college in Canada for expert knowledge on the pharmacology of brain function. This year’s conference was held in la belle ville de Montréal.... Read more »
aan het Rot M, Moskowitz DS, Pinard G, & Young SN. (2006) Social behaviour and mood in everyday life: the effects of tryptophan in quarrelsome individuals. Journal of psychiatry , 31(4), 253-62. PMID: 16862243
Dalley JW, Fryer TD, Brichard L, Robinson ES, Theobald DE, Lääne K, Peña Y, Murphy ER, Shah Y, Probst K.... (2007) Nucleus accumbens D2/3 receptors predict trait impulsivity and cocaine reinforcement. Science (New York, N.Y.), 315(5816), 1267-70. PMID: 17332411
Murphy SE. (2010) Using functional neuroimaging to investigate the mechanisms of action of selective serotonin reuptake inhibitors (SSRIs). Current pharmaceutical design, 16(18), 1990-7. PMID: 20370666
Sesack SR, Carr DB, Omelchenko N, & Pinto A. (2003) Anatomical substrates for glutamate-dopamine interactions: evidence for specificity of connections and extrasynaptic actions. Annals of the New York Academy of Sciences, 36-52. PMID: 14684434
The relative merits of medication versus behavioral treatment of ADHD continues to be an focus of concern for parents and researchers. It has been nearly 12 years since the publication of the classic study titled: Multimodal Treatment Study of Children with ADHD (MTA). This study compared children with ADHD assigned randomly to one of four treatment arms:stimulant drug treatment alone (titrated to response),intensive behavioral treatment alone, combined stimulant and behavioral ........ Read more »
[No authors listed]. (1999) A 14-month randomized clinical trial of treatment strategies for attention-deficit/hyperactivity disorder. The MTA Cooperative Group. Multimodal Treatment Study of Children with ADHD. Archives of general psychiatry, 56(12), 1073-86. PMID: 10591283
Tucha O, Tucha L, Kaumann G, König S, Lange KM, Stasik D, Streather Z, Engelschalk T, & Lange KW. (2011) Training of attention functions in children with attention deficit hyperactivity disorder. Attention deficit and hyperactivity disorders. PMID: 21597880
Do you write about peer-reviewed research in your blog? Use ResearchBlogging.org to make it easy for your readers — and others from around the world — to find your serious posts about academic research.
If you don't have a blog, you can still use our site to learn about fascinating developments in cutting-edge research from around the world.
Research Blogging is powered by SMG Technology.
To learn more, visit seedmediagroup.com.