Neuroscience posts
- May 19, 2013
- 11:52 PM
- 61 views
Blood magic: old blood ages the young
by Shelly Fan in Neurorexia
“Our ancient countess was refused her desires will To bathe in pure fresh blood She’d peasant virgins killed Elizabeth, in the chasm where was my soul Forever young, Elizabeth Bathorii in the castle of your death You’re still alive, Elizabeth” -“Elizabeth”, Ghost As folklore has it, Elizabeth Bathorii, Countess of Hungary, often bath........ Read more »
Villeda SA, Luo J, Mosher KI, Zou B, Britschgi M, Bieri G, Stan TM, Fainberg N, Ding Z, Eggel A.... (2011) The ageing systemic milieu negatively regulates neurogenesis and cognitive function. Nature, 477(7362), 90-4. PMID: 21886162
Loffredo FS, Steinhauser ML, Jay SM, Gannon J, Pancoast JR, Yalamanchi P, Sinha M, Dall'osso C, Khong D, Shadrach JL.... (2013) Growth Differentiation Factor 11 Is a Circulating Factor that Reverses Age-Related Cardiac Hypertrophy. Cell, 153(4), 828-39. PMID: 23663781
Zhang G, Li J, Purkayastha S, Tang Y, Zhang H, Yin Y, Li B, Liu G, & Cai D. (2013) Hypothalamic programming of systemic ageing involving IKK-β, NF-κB and GnRH. Nature, 497(7448), 211-6. PMID: 23636330
- May 19, 2013
- 09:29 AM
- 26 views
Fantastic Distortions of Perception
by Neuroskeptic in Neuroskeptic_Discover
A new paper in the journal European Neurology reports on a remarkable case of perceptual distortion that’ll please any connoisseur of neurogothic: A 48-year-old woman woke up one morning without knowing where she was. She recognized her husband and finally realized that she was at home, but reported that she felt that all surroundings appeared [...]... Read more »
Delgado MG, & Bogousslavsky J. (2013) 'Distorteidolias' - Fantastic Perceptive Distortion. A New, Pure Dorsomedial Thalamic Syndrome. European neurology, 70(1), 6-9. PMID: 23652461
- May 18, 2013
- 09:21 AM
- 60 views
Homeostatic platsicity in a thorny situation
by TheCellularScale in The Cellular Scale
Synapses, the connections between neurons can strengthen and weaken depending on the specific activity at that synapse. This is called synaptic plasticity, and we've talked about it a lot on this blog (here, here, here and here).the strengthening and weakening of synaptic connections corresponds to the spine growing or shrinking (Matsuzaki 2007)However, there is another kind of plasticity that can occur at synapses. This is called homeostatic plasticity. And instead of the synapse strengthening ........ Read more »
Lee KJ, Queenan BN, Rozeboom AM, Bellmore R, Lim ST, Vicini S, & Pak DT. (2013) Mossy fiber-CA3 synapses mediate homeostatic plasticity in mature hippocampal neurons. Neuron, 77(1), 99-114. PMID: 23312519
- May 16, 2013
- 12:07 PM
- 96 views
Good News or Bad News - Skin cancer and Alzheimer’s disease
by Usman Paracha in SayPeople
Main Point:
Researchers have found that the people, who develop skin cancer, may have less chances of developing Alzheimer’s disease in the older ages.
Published in:
Neurology
Study Further:
Alzheimer’s disease is a degenerative disorder that affects the brain and causes dementia, especially late in life.
In this new study, researchers worked on 1,102 volunteers with an average age of 79. They were studied for about 3.7 years. In the beginning of the study, 109 peop........ Read more »
White, R., Lipton, R., Hall, C., & Steinerman, J. (2013) Nonmelanoma skin cancer is associated with reduced Alzheimer disease risk. Neurology, 80(21), 1966-1972. DOI: 10.1212/WNL.0b013e3182941990
- May 16, 2013
- 11:16 AM
- 70 views
'Vocal mimicry hypothesis' falsified? [Part 2]
by Henkjan Honing in Music Matters
A few entries ago I uploaded a fragment from a study that discusses an intriguing experiment with three chimpanzees (Pan troglodytes) which were trained to tap regularly on a piano keyboard...... Read more »
Hattori, Y., Tomonaga, M., & Matsuzawa, T. (2013) Spontaneous synchronized tapping to an auditory rhythm in a chimpanzee. Scientific Reports. DOI: 10.1038/srep01566
Hasegawa, A., Okanoya, K., Hasegawa, T., & Seki, Y. (2011) Rhythmic synchronization tapping to an audio–visual metronome in budgerigars. Scientific Reports. DOI: 10.1038/srep00120
Honing, H., Merchant, H., Háden, G., Prado, L., & Bartolo, R. (2012) Rhesus Monkeys (Macaca mulatta) Detect Rhythmic Groups in Music, but Not the Beat. PLoS ONE, 7(12). DOI: 10.1371/journal.pone.0051369
- May 16, 2013
- 09:00 AM
- 13 views
The Psychological Science of Storytelling
Why is storytelling such an important thing in our everyday lives? Probably because everyone does it, but no one realizes it.
This article is about the power of storytelling, from your social life to the way stories affect your brain.... Read more »
Lacey S, Stilla R, & Sathian K. (2012) Metaphorically feeling: comprehending textural metaphors activates somatosensory cortex. Brain and language, 120(3), 416-21. PMID: 22305051
- May 16, 2013
- 08:38 AM
- 85 views
‘Brainbow,’ version 2.0
by Perikis Livas in Tracing Knowledge
The breakthrough technique that allowed scientists to obtain one-of-a-kind, colorful images of the myriad connections in the brain and nervous system is about to get a significant upgrade.... Read more »
Peter Reuell. (2013) ‘Brainbow,’ version 2.0. Harvard Gazette. info:/
- May 16, 2013
- 07:41 AM
- 77 views
The effectiveness of placebo treatment for pain is related to personality traits
by Scott McGreal in Eye on Psych
A recent study found that people high in agreeableness, ego-resiliency, and low in neuroticism have a stronger response to placebo pain relief. The placebo effect may be related to a person's capacity for self-control. ... Read more »
Peciña M, Azhar H, Love TM, Lu T, Fredrickson BL, Stohler CS, & Zubieta JK. (2013) Personality trait predictors of placebo analgesia and neurobiological correlates. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 38(4), 639-46. PMID: 23187726
- May 15, 2013
- 10:01 PM
- 67 views
Ladies: why Ritalin may not always be helpful. (Hint: sex, genes and dem hormones)
by Shelly Fan in Neurorexia
Little note: Since this post, I’ve been mulling over why Ritalin/Adderall don’t affect cognitive performance of healthy volunteers. Several reasons come to mind. I wasn’t reading the “right” literature (ie studies with positive results – any suggestions?). Stimulants may only influence brain activation patterns, but not performance. In this case, we can only detect differences […]... Read more »
Jacobs E, & D'Esposito M. (2011) Estrogen shapes dopamine-dependent cognitive processes: implications for women's health. The Journal of neuroscience : the official journal of the Society for Neuroscience, 31(14), 5286-93. PMID: 21471363
- May 15, 2013
- 04:50 PM
- 55 views
What RDoC Research Might Look Like
by The Neurocritic in The Neurocritic
The month of May is a violent thingIn the city their hearts start to singWell, some people sing, it sounds like they're screamingI used to doubt it, but now I believe itMonth Of May ------The Arcade FireToday is Mental Health Month Blog Day, sponsored by the American Psychological Association (APA). It's designed to:...educate the public about mental health, decrease stigma about mental illness, and discuss strategies for making lasting lifestyle and behavior changes that pro........ Read more »
Vaidyanathan, U., Nelson, L., & Patrick, C. (2011) Clarifying domains of internalizing psychopathology using neurophysiology. Psychological Medicine, 42(03), 447-459. DOI: 10.1017/S0033291711001528
Dichter, G., Damiano, C., & Allen, J. (2012) Reward circuitry dysfunction in psychiatric and neurodevelopmental disorders and genetic syndromes: animal models and clinical findings. Journal of Neurodevelopmental Disorders, 4(1), 19. DOI: 10.1186/1866-1955-4-19
- May 15, 2013
- 01:12 PM
- 66 views
You are what you eat – wait, no, you eat what you are. Wait, that’s not it…
by neuroecology in Neuroecology
The public will never tire of the nature versus nurture debate but here’s a hint: the answer in biology is always both. But if you’ve ever known any twins, you know they can have quite different personalities which, you would think, are attributable to differences in nurture of one sort or another. To understand this better, some scientists […]... Read more »
Freund, J., Brandmaier, A., Lewejohann, L., Kirste, I., Kritzler, M., Kruger, A., Sachser, N., Lindenberger, U., & Kempermann, G. (2013) Emergence of Individuality in Genetically Identical Mice. Science, 340(6133), 756-759. DOI: 10.1126/science.1235294
- May 13, 2013
- 09:43 AM
- 77 views
Bingeing and Purging: Keeping the “Positives” and Eliminating The Negatives?
by Liz in Science of Eating Disorders
I have been fascinated and perplexed by reports of the seemingly invigorating and anxiety reducing effects of bingeing and purging (purging by self-induced vomiting). Personally, I cringe at the idea of self-induced vomiting and have always wanted to avoid vomiting at all costs, including during food poisoning. The insight from recent blog entries and the subsequent comments has made an impact on me. I see that the motivation to engage in bingeing/purging (b/p-ing) behavior ........ Read more »
Avena, N., Rada, P., Moise, N., & Hoebel, B. (2006) Sucrose sham feeding on a binge schedule releases accumbens dopamine repeatedly and eliminates the acetylcholine satiety response. Neuroscience, 139(3), 813-820. DOI: 10.1016/j.neuroscience.2005.12.037
- May 13, 2013
- 05:47 AM
- 80 views
Experience leads to the growth of new brain cells
by Perikis Livas in Tracing Knowledge
How do organisms evolve into individuals that are distinguished from others by their own personal brain structure and behaviour? Scientists in Dresden, Berlin, Münster, and Saarbrücken have now taken a decisive step towards clarifying this question. Using mice as an animal model, they were able to show that individual experiences influence the development of new neurons, leading to measurable changes in the brain. The results of this study are published in Science on May 10th. The DFG-........ Read more »
Britta Grigull. (2013) Experience leads to the growth of new brain cells. Max Planck Institute for Human Development. info:/
- May 12, 2013
- 08:00 PM
- 74 views
The Inadvertent Psychological Experiment
by TheCellularScale in The Cellular Scale
Escape from Camp 14 is deeply disturbing, and I highly recommend it. Escape from Camp 14 by Blaine HardenEscape from Camp 14 is a chilling tale of Shin Dong-hyuk's escape from a North Korean prison camp. What is so interesting about Shin Dong-hyuk's story as written by Blaine Harden is that he was born inside this North Korean prison camp. Apparently they allow breeding between prisoners as a reward for 'good behavior.'Escape from Camp 14 reveals the obscene violations of human rights that occur........ Read more »
Lee YM, Shin OJ, & Lim MH. (2012) The psychological problems of north korean adolescent refugees living in South Korea. Psychiatry investigation, 9(3), 217-22. PMID: 22993519
- May 12, 2013
- 08:52 AM
- 95 views
A bright idea: Tiny injectable LEDs help neuroscientists study the brain
by Perikis Livas in Tracing Knowledge
A new class of tiny, injectable LEDs is illuminating the deep mysteries of the brain.
Researchers at the University of Illinois at Urbana-Champaign and Washington University in St. Louis developed ultrathin, flexible optoelectronic devices – including LEDs the size of individual neurons – that are lighting the way for neuroscientists in the field of optogenetics and beyond.... Read more »
Liz Ahlberg. (2013) A bright idea: Tiny injectable LEDs help neuroscientists study the brain. University of Illinois News Bureau. info:/
Kim, T., McCall, J., Jung, Y., Huang, X., Siuda, E., Li, Y., Song, J., Song, Y., Pao, H., Kim, R.... (2013) Injectable, Cellular-Scale Optoelectronics with Applications for Wireless Optogenetics. Science, 340(6129), 211-216. DOI: 10.1126/science.1232437
- May 12, 2013
- 05:49 AM
- 66 views
Visualizing the Connectome
by Neuroskeptic in Neuroskeptic_Discover
Last year, I blogged about a new and very pretty way of displaying the data about the human ‘connectome’ – the wiring between different parts of the brain. But there are many beautiful ways of visualizing the brain’s connections, as neuroscientists Daniel Margulies and colleagues of Leipzig discuss in a colourful paper showcasing these techniques. Here, [...]... Read more »
Margulies DS, Böttger J, Watanabe A, & Gorgolewski KJ. (2013) Visualizing the Human Connectome. NeuroImage. PMID: 23660027
- May 10, 2013
- 07:05 PM
- 87 views
What makes me, me? The cellular correlates of individuality
by Shelly Fan in Neurorexia
Somewhere in Germany, a group of 40 genetically identical females are being constantly watched. Implanted with radio-frequency identification transponders (RFID) since 4 weeks old, they are allowed to roam free in a rich, 5-storey mansion, with 20 antennas monitoring and recording their whereabouts. 3 months later their brains will be examined for traces of emerging […]... Read more »
Freund, J., Brandmaier, A., Lewejohann, L., Kirste, I., Kritzler, M., Kruger, A., Sachser, N., Lindenberger, U., & Kempermann, G. (2013) Emergence of Individuality in Genetically Identical Mice. Science, 340(6133), 756-759. DOI: 10.1126/science.1235294
- May 10, 2013
- 10:33 AM
- 102 views
Insula Activation as a Biomarker for Depression Risk
by William Yates, M.D. in Brain Posts
Right and Left Insula Cortex Highlighted in TealBiomarker research in brain disorders including schizophrenia and mood disorders is an important pathway to early identification and prevention.In a previous post, I reviewed a summary of current biomarker research in schizophrenia. This summary suggested that accelerated brain gray matter volume decline during childhood and adolescence is a candidate biomarker in schizophrenia.In this post, I will look at a similar imaging biomarker study in........ Read more »
Whalley HC, Sussmann JE, Romaniuk L, Stewart T, Papmeyer M, Sprooten E, Hackett S, Hall J, Lawrie SM, & McIntosh AM. (2013) Prediction of depression in individuals at high familial risk of mood disorders using functional magnetic resonance imaging. PloS one, 8(3). PMID: 23483904
- May 10, 2013
- 07:18 AM
- 66 views
Looking Into The Personality of Adventurers
by Katja Keuchenius in United Academics
Some feel the need to explore more than others. This apparently random characteristic really makes a difference to personalities, a mice experiment shows. Those that like to be adventurous and have the capacity to do so, develop different brains than those who stay mostly in the same place.... Read more »
Freund, J., Brandmaier, A., Lewejohann, L., Kirste, I., Kritzler, M., Kruger, A., Sachser, N., Lindenberger, U., & Kempermann, G. (2013) Emergence of Individuality in Genetically Identical Mice. Science, 340(6133), 756-759. DOI: 10.1126/science.1235294
- May 10, 2013
- 02:41 AM
- 70 views
Mitochondrial Disease – A Neurological Perspective
by Vivek Misra in Beautiful Mind
Defects of mitochondrial function have been identified in several neurodegenerative diseases. These include abnormalities induced by mutations of mitochondrial DNA (mtDNA) those caused by mutation of nuclear genes encoding mitochondrial proteins, and in some cases, exposure to mitochondrial toxins.MtDNA mutation are associated with a variety of progressive encephalomyopathies inn which there is evidence of neurodegeneration. These include Kearns-Sayre syndrome myopathy, encephalopathy, lac........ Read more »
McFarland R, Taylor RW, & Turnbull DM. (2010) A neurological perspective on mitochondrial disease. Lancet neurology, 9(8), 829-40. PMID: 20650404
Venna N. (2004) Mitochondrial neurological diseases: a clinician's perspective. Neurology India, 52(3), 305-6. PMID: 15472416
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