Clinical Research posts from Today
- September 2, 2010
- 12:08 PM
- 10 views
Diabetes drug may protect against cancer
by Sally Church in Pharma Strategy Blog
Yesterday, I covered some of the key pathways and kinases associated with cell energy metabolism, LKB1 and AMPK. These, together with Insulin-like Growth Factor-I (IGF-I) and the insulin receptor (IR), appear to play important roles in the broader regulation of...... Read more »
Douglas JB, Silverman DT, Pollak MN, Tao Y, Soliman AS, & Stolzenberg-Solomon RZ. (2010) Serum IGF-I, IGF-II, IGFBP-3, and IGF-I/IGFBP-3 Molar Ratio and Risk of Pancreatic Cancer in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial. Cancer epidemiology, biomarkers . PMID: 20699371
Tao Y, Pinzi V, Bourhis J, & Deutsch E. (2007) Mechanisms of disease: signaling of the insulin-like growth factor 1 receptor pathway--therapeutic perspectives in cancer. Nature clinical practice. Oncology, 4(10), 591-602. PMID: 17898809
Chitnis MM, Yuen JS, Protheroe AS, Pollak M, & Macaulay VM. (2008) The type 1 insulin-like growth factor receptor pathway. Clinical cancer research : an official journal of the American Association for Cancer Research, 14(20), 6364-70. PMID: 18927274
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