Three fast track articles were recently published on CyberPsychology and Behavior about the treatment of PTSD with virtual reality exposure therapy. Exposure therapy is the most evidence based treatment for Post Traumatic Stress Disorder (PTSD). More than 18 studies have been published on the use of virtual reality exposure treatment for PTSD.
One of [...]
Related posts:Virtual Reality Becomes Real The latest multi-core processors and some smart software allow...
Augmented reality made eas........ Read more »
McLay, R., McBrien, C., Wiederhold, M., & Wiederhold, B. (2009) Exposure Therapy with and without Virtual Reality to Treat PTSD while in the Combat Theater: A Parallel Case Series. CyberPsychology , 2147483647. DOI: 10.1089/cpb.2009.0346
Gamito, P., Oliveira, J., Rosa, P., Morais, D., Duarte, N., Oliveira, S., & Saraiva, T. (2009) PTSD Elderly War Veterans: A Clinical Controlled Pilot Study. CyberPsychology , 2147483647. DOI: 10.1089/cpb.2009.0237
Botella, C., García-Palacios, A., Guillen, V., Baños, R., Quero, S., & Alcaniz, M. (2009) An Adaptive Display for the Treatment of Diverse Trauma PTSD Victims. CyberPsychology , 2147483647. DOI: 10.1089/cpb.2009.0353
Some of you may know that I’ve just had surgery, and I’m gently recovering from the comfort of my own home over the next few weeks. Posts on here will be intermittent but I find myself considering aspects of pain management from a ‘patient’s’ perspective today as it’s about 5 days since surgery and my [...]... Read more »
Leegaard, M., Nåden, D., & Fagermoen, M. (2008) Postoperative pain and self-management: women’s experiences after cardiac surgery. Journal of Advanced Nursing, 63(5), 476-485. DOI: 10.1111/j.1365-2648.2008.04727.x
Two papers and an editorial in the latest issue of Archives of Internal Medicine examine the cancer risks associated with the use of computed tomography (CT) examinations.... Read more »
Smith-Bindman, R., Lipson, J., Marcus, R., Kim, K., Mahesh, M., Gould, R., Berrington de Gonzalez, A., & Miglioretti, D. (2009) Radiation Dose Associated With Common Computed Tomography Examinations and the Associated Lifetime Attributable Risk of Cancer. Archives of Internal Medicine, 169(22), 2078-2086. DOI: 10.1001/archinternmed.2009.427
Berrington de Gonzalez, A., Mahesh, M., Kim, K., Bhargavan, M., Lewis, R., Mettler, F., & Land, C. (2009) Projected Cancer Risks From Computed Tomographic Scans Performed in the United States in 2007. Archives of Internal Medicine, 169(22), 2071-2077. DOI: 10.1001/archinternmed.2009.440
Redberg, R. (2009) Cancer Risks and Radiation Exposure From Computed Tomographic Scans: How Can We Be Sure That the Benefits Outweigh the Risks?. Archives of Internal Medicine, 169(22), 2049-2050. DOI: 10.1001/archinternmed.2009.453
This week’s Lancet features an article entitled, “Variant CJD in an individual heterozygous for PRNP codon 129” by Kaski and colleagues. The authors report the first case of probable variant Creutzfeldt-Jakob disease (vCJD) in an individual who is heterozygous at codon 129 of the prion protein gene (PRNP). To date, all symptomatic cases have occurred in individuals who are homozygous for methionine at codon 129. As we know from other studies (Brown P, 1994), the incubatio........ Read more »
Kaski, D., Mead, S., Hyare, H., Cooper, S., Jampana, R., Overell, J., Knight, R., Collinge, J., & Rudge, P. (2010) Variant CJD in an individual heterozygous for PRNP codon 129. The Lancet, 374(9707), 2128-2128. DOI: 10.1016/S0140-6736(09)61568-3
According to a study just out in the American Journal of Psychiatry, starting depressed people on two antidepressants leads to much better results than starting them on just one - Combination of Antidepressant Medications From Treatment Initiation for Major Depressive Disorder. But how reliable is it?Currently accepted practice is to prescribe one antidepressant to begin with, and if the patient doesn't feel better after about 6 weeks, to either change to a different antidepressant (switching) o........ Read more »
Blier, P., Ward, H., Tremblay, P., Laberge, L., Hebert, C., & Bergeron, R. (2009) Combination of Antidepressant Medications From Treatment Initiation for Major Depressive Disorder: A Double-Blind Randomized Study. American Journal of Psychiatry. DOI: 10.1176/appi.ajp.2009.09020186
Physicians are under mounting pressure to increase efficiency in the provision of medical care. That is, see more patients in less time for less money. But, since speed and accuracy do not always go hand-in-hand, does this increased physician efficiency lead to quality medical care? A recent study published in the Archives of Internal Medicine [...]... Read more »
Olfson, M., Cherry, D., & Lewis-Fernandez, R. (2009) Racial Differences in Visit Duration of Outpatient Psychiatric Visits. Archives of General Psychiatry, 66(2), 214-221. DOI: 10.1001/archgenpsychiatry.2008.523
Chen, L., Farwell, W., & Jha, A. (2009) Primary Care Visit Duration and Quality: Does Good Care Take Longer?. Archives of Internal Medicine, 169(20), 1866-1872. DOI: 10.1001/archinternmed.2009.341
Linder, J. (2003) Association between antibiotic prescribing and visit duration in adults with upper respiratory tract infections. Clinical Therapeutics, 25(9), 2419-2430. DOI: 10.1016/S0149-2918(03)80284-9
Lo, A., Ryder, K., & Shorr, R. (2005) Relationship Between Patient Age and Duration of Physician Visit in Ambulatory Setting: Does One Size Fit All?. Journal of the American Geriatrics Society, 53(7), 1162-1167. DOI: 10.1111/j.1532-5415.2005.53367.x
Despite their heavyweight name, SUMO proteins are a family of small proteins found in our cells, which, by sticking to other proteins, can regulate all sorts of cellular goings-on.
For example, sticking a SUMO protein onto another protein can shuttle it to a different location in the cell, or alter how it works.
And there’s tantalising evidence [...]... Read more »
Morris, J., Boutell, C., Keppler, M., Densham, R., Weekes, D., Alamshah, A., Butler, L., Galanty, Y., Pangon, L., Kiuchi, T.... (2009) The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress. Nature, 462(7275), 886-890. DOI: 10.1038/nature08593
Galanty, Y., Belotserkovskaya, R., Coates, J., Polo, S., Miller, K., & Jackson, S. (2009) Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks. Nature, 462(7275), 935-939. DOI: 10.1038/nature08657
It’s been a bumper week for cancer research. As we report elsewhere, scientists have been delving deep into our cells’ DNA repair mechanisms, and finding out how they tick.
At the opposite end of the spectrum, two more papers published in Nature today look at what happens when DNA repair goes wrong, by mapping DNA damage [...]... Read more »
Pleasance, E., Cheetham, R., Stephens, P., McBride, D., Humphray, S., Greenman, C., Varela, I., Lin, M., Ordóñez, G., Bignell, G.... (2009) A comprehensive catalogue of somatic mutations from a human cancer genome. Nature. DOI: 10.1038/nature08658
Pleasance, E., Stephens, P., O’Meara, S., McBride, D., Meynert, A., Jones, D., Lin, M., Beare, D., Lau, K., Greenman, C.... (2009) A small-cell lung cancer genome with complex signatures of tobacco exposure. Nature. DOI: 10.1038/nature08629
Shah, S., Morin, R., Khattra, J., Prentice, L., Pugh, T., Burleigh, A., Delaney, A., Gelmon, K., Guliany, R., Senz, J.... (2009) Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution. Nature, 461(7265), 809-813. DOI: 10.1038/nature08489
One of my personal interests is the relationship between sedentary time (e.g. the amount of time that we spend sitting) and chronic disease risk. Several interesting papers have come out in the past few years suggesting that spending too much time sitting down is a risk factor for obesity, chronic disease, and even death, independent of physical activity levels. In other words, no matter how physically active you are, the more time you spend sitting, the greater your risk of death and disease......... Read more »
Dunton, G., Berrigan, D., Ballard-Barbash, R., Graubard, B., & Atienza, A. (2009) Joint associations of physical activity and sedentary behaviors with body mass index: results from a time use survey of US adults. International Journal of Obesity, 33(12), 1427-1436. DOI: 10.1038/ijo.2009.174
The relationship between personality and political preferences is not the simple relation between conservatism and negative personality traits on the one hand and liberalism and positive personality traits on the other hand. Personality is understood as the combination of innate dispositions and personal experiences that guides behavior in a stable and predictive manner. Behavior is [...]
Related posts:Maturation of Personality in Adolescence Haven’t written about adolescence for some ........ Read more »
Verhulst, B., Hatemi, P., & Martin, N. (2009) The nature of the relationship between personality traits and political attitudes. Personality and Individual Differences. DOI: 10.1016/j.paid.2009.11.013
Is the research community doing as much as it might to extract value from the diversity in life span amongst mammals? Certainly there are those scientist who would like to be engaged in a great deal more sequencing and biochemical deciphering of long-lived animals. But on the whole, I think that less is taking place in this area of study than might be. See this paper from a noted gerontologist, for example: As impressive as the accomplishments of modern molecular biologists have been in finding ........ Read more »
Austad SN. (2009) Methusaleh's Zoo: How Nature provides us with Clues for Extending Human Health Span. Journal of comparative pathology. PMID: 19962715_id
Previously we discussed the neurobiology of falling in love. But this is only the beginning, the process of attraction followed by the attachment process. This process can develop and last for a while or in some cases for ever. Biologically is falling in love the first step in pair formation.
Falling in love is more accompanied [...]
Related posts:The Neurobiology of Falling in Love Falling in love is the most overwhelming of all...Love is Great for Creativity, Sex for Analytical Thinking M........ Read more »
Sci saw this post recently at Dr. Pal's place, and it rang some major bells in her head. So, I figure, I've got to cover it myself, now don't I.
Lim et al. "Zican-induced damage to mouse and human nasal tissue" PLoS ONE, 2009.
So let's start with a couple of things:
1) What is Zicam?
2) Why was it recalled?
3) What are the possible effects of zinc on the common cold? Read the rest of this post... | Read the comments on this post...... Read more »
Lim JH, Davis GE, Wang Z, Li V, Wu Y, Rue TC, & Storm DR. (2009) Zicam-induced damage to mouse and human nasal tissue. PloS one, 4(10). PMID: 19876403
by David Gorski in Science-Based Medicine
It’s been about a year and a half since I’ve written about this topic; so I thought I’d better update the disclaimer that I wrote at the beginning:
Before I start into the meat of this post, I feel the need to emphasize, as strongly as I can, four things:
I do not receive any funding from [...]... Read more »
Myung, S., Ju, W., McDonnell, D., Lee, Y., Kazinets, G., Cheng, C., & Moskowitz, J. (2009) Mobile Phone Use and Risk of Tumors: A Meta-Analysis. Journal of Clinical Oncology, 27(33), 5565-5572. DOI: 10.1200/JCO.2008.21.6366
Deltour, I., Johansen, C., Auvinen, A., Feychting, M., Klaeboe, L., & Schuz, J. (2009) Time Trends in Brain Tumor Incidence Rates in Denmark, Finland, Norway, and Sweden, 1974-2003. JNCI Journal of the National Cancer Institute. DOI: 10.1093/jnci/djp415
The statistics are everywhere: most of the adults in the United States are overweight or obese. These conditions are, of course, responsible for increased health care costs owing to chronic diseases such as diabetes, high blood pressure, high cholesterol, and heart disease. The patient may pick up some of these excess expenses, but society incurs [...]... Read more »
Anderson, L., Quinn, T., Glanz, K., Ramirez, G., Kahwati, L., Johnson, D., Buchanan, L., Archer, W., Chattopadhyay, S., & Kalra, G. (2009) The Effectiveness of Worksite Nutrition and Physical Activity Interventions for Controlling Employee Overweight and ObesityA Systematic Review. American Journal of Preventive Medicine, 37(4), 340-357. DOI: 10.1016/j.amepre.2009.07.003
Lightwood, J., Bibbins-Domingo, K., Coxson, P., Wang, Y., Williams, L., & Goldman, L. (2009) Forecasting the Future Economic Burden of Current Adolescent Overweight: An Estimate of the Coronary Heart Disease Policy Model. American Journal of Public Health, 99(12), 2230-2237. DOI: 10.2105/AJPH.2008.152595
Clarke, P., O'Malley, P., Johnston, L., & Schulenberg, J. (2008) Social disparities in BMI trajectories across adulthood by gender, race/ethnicity and lifetime socio-economic position: 1986-2004. International Journal of Epidemiology, 38(2), 499-509. DOI: 10.1093/ije/dyn214
Heraclides, A., & Brunner, E. (2009) Social mobility and social accumulation across the life-course in relation to adult overweight and obesity: The Whitehall II study. Journal of Epidemiology . DOI: 10.1136/jech.2009.087692
I’ve had two children – now 19 and 16, and wonderful. At the time of their delivery I can remember both times thinking ‘as long as they’re healthy’ and being not at all worried about having medical intervention if it was needed. My eldest was born with epidural anaesthesia, and my youngest was [...]... Read more »
Lavand’homme, P. (2009) Chronic pain after vaginal and cesarean delivery: a reality questioning our daily practice of obstetric anesthesia. International Journal of Obstetric Anesthesia. DOI: 10.1016/j.ijoa.2009.09.003
Some nagging uncertainties remain on progress in stem cell medicine - and especially progress in reprogramming easily obtained somatic cells into patient-specific pluripotent stem cells. These uncertainties will be answered and addressed in the years ahead, but this one springs to mind today: it is possible that cells from older people may be altered or damaged in ways that prevent their effective use as-is in the sort of autologous stem cell therapies presently envisaged. That would be a setbac........ Read more »
Suhr, S., Chang, E., Rodriguez, R., Wang, K., Ross, P., Beyhan, Z., Murthy, S., & Cibelli, J. (2009) Telomere Dynamics in Human Cells Reprogrammed to Pluripotency. PLoS ONE, 4(12). DOI: 10.1371/journal.pone.0008124
Very recently, an interesting study was published looking at the risk of early mortality among metabolically-healthy obese individuals – a topic we’ve covered on a number of occasions on Obesity Panacea. The authors of this landmark study published in the journal Diabetes Care are actually close friends of ours (Dr. Jennifer Kuk and Dr. Christopher Ardern), and both are alumni of Queen’s university. Now that the media frenzy surrounding their recent study has subsided, Dr. Kuk ........ Read more »
Kuk, J., & Ardern, C. (2009) Are Metabolically Normal but Obese Individuals at Lower Risk for All-Cause Mortality?. Diabetes Care, 32(12), 2297-2299. DOI: 10.2337/dc09-0574
For Sci, the weird science tends to come in spurts (heh heh...heh). There will be times when I am literally digging through Pubmed trying to find ANYTHING ODD AT ALL, and then there are times, like now, when people are tweeting and emailing and g-chatting and all but screaming in my ear with the weird. Got enough crazy sexual crap around here to last for WEEKS.
And a good thing, too, cause it's all about premature ejaculation, and don't we all wish we could last for weeks...
So we........ Read more »
Waldinger, M., Quinn, P., Dilleen, M., Mundayat, R., Schweitzer, D., & Boolell, M. (2005) A Multinational Population Survey of Intravaginal Ejaculation Latency Time. The Journal of Sexual Medicine, 2(4), 492-497. DOI: 10.1111/j.1743-6109.2005.00070.x
Arguably, the genesis of the most recent iteration of the anti-vaccine movement dates back to 1998, when a remarkably incompetent researcher named Andrew Wakefield published a trial lawyer-funded "study" in the Lancet that purported to find a link between "autistic enterocolitis" and measles vaccination with the measles-mumps-rubella (MMR) trivalent vaccine. In the wake of that publication was born a scare over the MMR that persists to this day, 11 years later. Although peer reviewers forced the........ Read more »
Mrożek-Budzyn D, Kiełtyka A, & Majewska R. (2009) Lack of Association Between Measles-Mumps-Rubella Vaccination and Autism in Children: A Case-Control Study. The Pediatric infectious disease journal. PMID: 19952979
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