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  • April 23, 2013
  • 06:15 AM

fMRI lie detection and the Semrau case

by Know Your Images in Know Your Images

Semrau is a psychologist accused of committing fraud to Medicare and Medicaid. The case became mostly famous, because he asked that fMRI lie detection would be a evidence in court. The judge had to decide if fMRI was admissible and after hearing scientists advocating for both sides, he has decided not to admit such evidence. However, the question is: Will it be possible to use fMRI lie detection one day?, because the reason for not admitting it has been based on the error rates and acceptance by........ Read more »

Kozel, F., Johnson, K., Mu, Q., Grenesko, E., Laken, S., & George, M. (2005) Detecting Deception Using Functional Magnetic Resonance Imaging. Biological Psychiatry, 58(8), 605-613. DOI: 10.1016/j.biopsych.2005.07.040  

  • April 22, 2013
  • 08:20 PM

Connecting Form and Function: Serial Block-face EM

by TheCellularScale in The Cellular Scale

The retina is a beautiful and wondrous structure, and it has some really weird cells. Retina by Cajal (source)Retinal Ganglion Cells (RGC) have all sorts of differentiating characteristics. Some are directly sensitive to brightness (like rods and cones), while some are sensitive to the specific direction that a bar is traveling. I am discussing really amazing new techniques to see inside cells this month, and have already posted about the magic that is Array Tomography. Today we'll look at anoth........ Read more »

  • April 20, 2013
  • 04:00 AM

Will the droids take academic jobs?

by Artem Kaznatcheev in Evolutionary Games Group

As a researcher, one of the biggest challenges I face is keeping up with the scientific literature. This is further exasperated by working in several disciplines, and without a more senior advisor or formal training in most of them. The Evolutionary Game Theory Reading Group, and later this blog, started as an attempt to help [...]... Read more »

  • April 19, 2013
  • 03:53 AM

Decoding the structure of bone

by Perikis Livas in Chilon

[...] a team of researchers at MIT has finally unraveled the structure of bone with almost atom-by-atom precision, after many years of analysis by some of the world’s most powerful computers and comparison with laboratory experiments to confirm the computed results [...]... Read more »

David L. Chandler. (2013) Decoding the structure of bone. MIT News Office. info:/

  • April 16, 2013
  • 06:25 AM

Nanosponges Soak Up Toxins Released by Bacterial Infections and Venom

by Perikis Livas in Chilon

Engineers at the University of California, San Diego have invented a “nanosponge” capable of safely removing a broad class of dangerous toxins from the bloodstream – including toxins produced by MRSA, E. coli, poisonous snakes and bees.... Read more »

Catherine Hockmuth, & Daniel Kane. (2013) Nanosponges Soak Up Toxins Released by Bacterial Infections and Venom. UC San Diego News Center. info:/

  • April 15, 2013
  • 04:46 PM

Greece's ups and downs

by Perikis Livas in Chilon

A new data processor is creating maps of land deformation from satellite radar data over larger areas and with higher precision than ever before. These maps can be used to detect and monitor geological hazards.... Read more »

ESA Observing the Earth. (2013) Greece's ups and downs. ESA Observing the Earth. info:/

  • April 15, 2013
  • 03:27 PM

Brain-to-Brain Interface - Share Information via Internet

by Vivek Misra in Uberbrain Research Frontier

Normal 0 false false false EN-US X-NONE X-NONE ... Read more »

  • April 15, 2013
  • 05:30 AM

Mathematical Turing test: Readable proofs from your computer

by Artem Kaznatcheev in Evolutionary Games Group

We have previously discussed the finicky task of defining intelligence, but surely being able to do math qualifies? Even if the importance of mathematics in science is questioned by people as notable as E.O. Wilson, surely nobody questions it as an intelligent activity? Mathematical reasoning is not necessary for intelligence, but surely it is sufficient? [...]... Read more »

  • April 11, 2013
  • 10:50 AM

Human organ-on-chips: An alternative approach to drug and toxin testing?

by Professor Donald Ingber in NC3Rs Blog

In this first post, our 2012 NC3Rs 3Rs Prize winner, Professor Donald Ingber at the Wyss Institute for Biologically Inspired Engineering, Harvard University, USA, describes how his prize-winning lung-on-a-chip microdevice could change the face of how we test drugs and model human disease in the future.... Read more »

Huh, D., Leslie, D., Matthews, B., Fraser, J., Jurek, S., Hamilton, G., Thorneloe, K., McAlexander, M., & Ingber, D. (2012) A Human Disease Model of Drug Toxicity-Induced Pulmonary Edema in a Lung-on-a-Chip Microdevice. Science Translational Medicine, 4(159), 159-159. DOI: 10.1126/scitranslmed.3004249  

  • April 10, 2013
  • 12:06 PM

The Effects of Social Media Monopolies

by Mark Fonseca Rendeiro in United Academics

Though some new statistical reports show signs of slowing down, we are still very much in the era of social media euphoria, where more and more people join up, sign in, and check their feeds as often as possible. ”Like” it or not- grievances are aired, ideas are sometimes exchanged, and a never ending stream of baby photos are shared at every minute of the day. On the surface, both regular users and professional researchers have observed and chronicled the list of achievements and p........ Read more »

  • April 10, 2013
  • 09:12 AM

The Effects of Social Media Monopolies

by Mark Fonseca Rendeiro in United Academics

Though some new statistical reports show signs of slowing down, we are still very much in the era of social media euphoria, where more and more people join up, sign in, and check their feeds as often as possible. ”Like” it or not- grievances are aired, ideas are sometimes exchanged, and a never ending stream of baby photos are shared at every minute of the day. On the surface, both regular users and professional researchers have observed and chronicled the list of achievements and p........ Read more »

  • April 8, 2013
  • 02:02 PM

A mighty wind

by Perikis Livas in Chilon

Thrusters powered by ionic wind may be an efficient alternative to conventional atmospheric propulsion technologies.... Read more »

Jennifer Chu. (2013) A mighty wind. MIT News Office. info:/

  • April 8, 2013
  • 12:00 PM

Programming playground: Cells as (quantum) computers?

by Artem Kaznatcheev in Evolutionary Games Group

Nearly a year ago, the previous post in this series introduced a way for programmers to play around with biology: a model that simulated the dynamics of a whole cell at unprecedented levels of details. But what if you want to play with the real thing? Can you program a living cell? Can you compute [...]... Read more »

Bonnet J, Yin P, Ortiz ME, Subsoontorn P, & Endy D. (2013) Amplifying Genetic Logic Gates. Science. PMID: 23539178  

  • April 2, 2013
  • 12:12 PM

The Misguided Search for Validation via Social Media

by Jason Carr in Wired Cosmos

We human beings are social creatures. It’s natural for us to orient ourselves in terms of the world outside and what the people around us are thinking and doing. This socialization instinct is strongest in us when we’re young and still developing our own sense of identity. Historically speaking, this dynamic has typically played itself … Read More →... Read more »

  • April 2, 2013
  • 11:28 AM

Film preparations for oral drug delivery

by Maren Preis in Pharmaceutical Solid State Research Cluster (PSSRC)

Oral films have gained interest in the last couple of years. Films for oral application offer an interesting new approach for drug administration. Active pharmaceutical ingredients (API) can be implemented in thin-sheeted polymer film matrices. These dosage forms are intended to be placed in mouth to dissolve in the saliva without the need of additional liquid and without swallowing of a solid dosage form.... Read more »

Hoffmann EM, Breitenbach A, & Breitkreutz J. (2011) Advances in orodispersible films for drug delivery. Expert opinion on drug delivery, 8(3), 299-316. PMID: 21284577  

Janßen E.M., Schliephacke R,, Breitenbach A,, & Breitkreutz J. (2013) Drug-printing by flexographic printing technology—A new manufacturing process for orodispersible films. International Journal of Pharmaceutics, 441(1-2), 818-825. info:/10.1016/j.ijpharm.2012.12.023

Garsuch V, & Breitkreutz J. (2009) Novel analytical methods for the characterization of oral wafers. European Journal of Pharmaceutics and Biopharmaceutics, 73(1), 195-201. PMID: 19482082  

Woertz K, Tissen C, Kleinebudde P, & Breitkreutz J. (2011) Taste sensing systems (electronic tongues) for pharmaceutical applications. International journal of pharmaceutics, 417(1-2), 256-71. PMID: 21094230  

  • March 29, 2013
  • 09:11 AM

Scientists Detect Magnetic Fingerprints of Defects in Solar Cells

by dailyfusion in The Daily Fusion

A new highly sensitive method of measurement allowed physicists form Helmholtz-Zentrum Berlin for Materials and Energy to directly detect defects in solar cells with atomic resolution. This findings can be used to optimize solar cells’ efficiency and decrease production costs.

HZB physicists have managed to localize defects in amorphous/crystalline silicon heterojunction solar cells. Now, for the first time ever, using computer simulations at Paderborn University, the scientists were ........ Read more »

George, B., Behrends, J., Schnegg, A., Schulze, T., Fehr, M., Korte, L., Rech, B., Lips, K., Rohrmüller, M., Rauls, E.... (2013) Atomic Structure of Interface States in Silicon Heterojunction Solar Cells. Physical Review Letters, 110(13). DOI: 10.1103/PhysRevLett.110.136803  

  • March 28, 2013
  • 10:01 AM

Texas Unleashes Stampede for Science

by Perikis Livas in Chilon

Stampede, the newest supercomputer at the Texas Advanced Computing Center (TACC) and one of the most advanced scientific research instruments in the world, fills aisle after aisle of a new 11,000-square-foot data center on the J.J. Pickle Research Campus. Through the glass machine room doors, you can see 182 racks holding more than 500,000 interconnected computer processors. Inside, wind whips from in-row coolers, wires snake over the racks and chilled water courses below the floor as Stampede p........ Read more »

Aaron Dubrow. (2013) Texas Unleashes Stampede for Science. UT - Texas Advanced Computing Center. info:/

  • March 27, 2013
  • 09:45 AM

Video Tip of the Week: Enzyme Portal and User-Centered Design

by Mary in OpenHelix

This week’s video tip of the week introduces you to Enzyme Portal, an interface to explore data about these important proteins, from the EBI. In the video, Jenny Cham–one of the authors of the paper below–takes you through the main features of their newly designed resource. I learned about the new effort from this blog [...]... Read more »

de Matos, P., Cham, J., Cao, H., Alcántara, R., Rowland, F., Lopez, R., & Steinbeck, C. (2013) The Enzyme Portal: A case study in applying user-centred design methods in bioinformatics. BMC Bioinformatics, 14(1), 103. DOI: 10.1186/1471-2105-14-103  

  • March 27, 2013
  • 08:27 AM

Modern Privacy: More Access to Cells than Toilets

by Katja Keuchenius in United Academics

Most people in the world now live in a city, feeling pretty anonymous. An even bigger number of people don’t have to defocate out in the open anymore, but have access to a toilet. And then there’s this growing amount of people that can talk in private on their cells. But beware, these are false senses of privacy.... Read more »

de Montjoye YA, Hidalgo CA, Verleysen M, & Blondel VD. (2013) Unique in the Crowd: The privacy bounds of human mobility. Scientific reports, 1376. PMID: 23524645  

  • March 26, 2013
  • 08:48 AM

Breakthrough Research Shows Chemical Reaction in Real Time

by Perikis Livas in Chilon

The ultrafast, ultrabright X-ray pulses of the Linac Coherent Light Source (LCLS) have enabled unprecedented views of a catalyst in action, an important step in the effort to develop cleaner and more efficient energy sources.

Scientists at the U.S. Department of Energy’s (DOE) SLAC National Accelerator Laboratory used LCLS, together with computerized simulations, to reveal surprising details of a short-lived early state in a chemical reaction occurring at the surface of a catalyst sampl........ Read more »

Andy Freeberg. (2013) Breakthrough Research Shows Chemical Reaction in Real Time. SLAC National Accelerator Laboratory News. info:/

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