- June 11, 2009
- 02:54 PM
- 465 views
Unfolding the role of the hypoxic response in aging
by ouroboros in Ouroboros: Research in the biology of aging
The TOR (”target of rapamycin”) protein is a master regulator of cell growth, governing connect nutrient sensing, protein synthesis, and proliferation. It has become increasingly clear that the TOR pathway plays an essential role in longevity determination — specifically, higher TOR activity is associated with more rapid aging and shorter lifespan.
In mammals, TOR interferes [...]... Read more »
Chen, D., Thomas, E., & Kapahi, P. (2009) HIF-1 Modulates Dietary Restriction-Mediated Lifespan Extension via IRE-1 in Caenorhabditis elegans. PLoS Genetics, 5(5). DOI: 10.1371/journal.pgen.1000486
- May 22, 2009
- 02:40 PM
- 337 views
Cómo el comer poco hace que vivas más
by César Tomé López in Experientia docet
Los estudios que se están llevando a cabo con Caenorhabditis elegans [en la imagen] están permitiendo comprender los mecanismos por los cuales una dieta restrictiva hace que vivamos más tiempo y con menor incidencia de enfermedades como el cáncer.... Read more »
Chen, D., Thomas, E., & Kapahi, P. (2009) HIF-1 Modulates Dietary Restriction-Mediated Lifespan Extension via IRE-1 in Caenorhabditis elegans. PLoS Genetics, 5(5). DOI: 10.1371/journal.pgen.1000486
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