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  • December 23, 2016
  • 05:03 AM
  • 403 views

ADHD symptoms and chronic fatigue syndrome?

by Paul Whiteley in Questioning Answers

With the pinnacle of the season of 'jolly' almost upon us, I'd like to make some brief discussion on the findings reported by Denise Rogers and colleagues [1] and specifically the observation that: "ADHD [attention-deficit hyperactivity disorder] symptoms were significantly greater in the CFS [chronic fatigue syndrome] group than in HC [healthy controls]."With the aim of examining both the prevalence of fatigue in cases of ADHD and the prevalence of ADHD symptoms in adults wi........ Read more »

  • December 22, 2016
  • 03:31 AM
  • 398 views

Psychosis (sometimes) as an immune disorder?

by Paul Whiteley in Questioning Answers

"Some psychosis cases an 'immune disorder'" went the BBC headline with reference to the paper by Belinda Lennox and colleagues [1] talking about the detection of antibodies against the N-methyl-D-aspartate receptor (NMDAR) in cases of first-episode psychosis (FEP).Although by no means a universal phenomenon, researchers reported that 3% of their 228 participants diagnosed with FEP who provided a blood sample showed the presence of NMDAR antibodies compared with none of the healthy controls ........ Read more »

  • December 21, 2016
  • 06:02 AM
  • 433 views

"New form of autism found"

by Paul Whiteley in Questioning Answers

"New form of autism found" went one of the headlines reporting on the paper by Dora C. Tărlungeanu and colleagues [1] and findings that "elucidate a neurological syndrome defined by SLC7A5 mutations and support an essential role for the BCAA [branched-chain amino acids] in human brain function." This work continues a rather important research story talking about how one 'type' of autism might have some important roots in relation to the branched-chain amino acids and their m........ Read more »

Tărlungeanu, D., Deliu, E., Dotter, C., Kara, M., Janiesch, P., Scalise, M., Galluccio, M., Tesulov, M., Morelli, E., Sonmez, F.... (2016) Impaired Amino Acid Transport at the Blood Brain Barrier Is a Cause of Autism Spectrum Disorder. Cell, 167(6), 1481-2147483647. DOI: 10.1016/j.cell.2016.11.013  

  • December 20, 2016
  • 11:15 AM
  • 462 views

10 scientifically proven ways to influence or know the people silently

by Usman Paracha in SayPeople

Want to know if someone is interested? Watch their pupils

The pupils are among those parts of body languages that are not in our conscious control. White and Maltzman (1977) found that the pupil starts dilating when a person shows interest in some other person he or she talking to.

Via: Psyblog

Feet

Want to know the person is into you? Watch the feet

Most people know how to keep a check on their expressions, but they are unaware about their feet. So, if a person is interested in........ Read more »

  • December 20, 2016
  • 04:33 AM
  • 422 views

Generation R does gestational vitamin D levels and autistic traits

by Paul Whiteley in Questioning Answers

"Gestational vitamin D deficiency was associated with autism-related traits in a large population-based sample. Because gestational vitamin D deficiency is readily preventable with safe, cheap and accessible supplements, this candidate risk factor warrants closer scrutiny."So said the findings reported by Vinkhuyzen and colleagues [1] (open-access) reporting on data derived from "the Generation R Study, a population-based prospective cohort from fetal life onward, based in Rotterdam, The Netherl........ Read more »

Vinkhuyzen AA, Eyles DW, Burne TH, Blanken LM, Kruithof CJ, Verhulst F, Jaddoe VW, Tiemeier H, & McGrath JJ. (2016) Gestational vitamin D deficiency and autism-related traits: the Generation R Study. Molecular psychiatry. PMID: 27895322  

  • December 19, 2016
  • 08:43 AM
  • 386 views

I am morally superior to others and also less biased than  everyone….

by Doug Keene in The Jury Room

While you may think you have heard this line recently, this is really (based on new research) what most of us think about ourselves. It is called the “better than average effect” and it is very persistent. We might smirk at politicians who actually say things like this aloud, but that’s only because we tend […]... Read more »

  • December 19, 2016
  • 04:52 AM
  • 495 views

Neuroscience Spots Potential Criminals In Pre-School?

by Neuroskeptic in Neuroskeptic_Discover

A new post at Quartz discusses
The disturbingly accurate brain science that identifies potential criminals while they’re still toddlers... scientists are able to use brain tests on three-year-olds to determine which children are more likely to grow up to become criminals.


Hmmm. Not really.

The research in question is from from North Carolina researchers Avshalom Caspi et al.: Childhood forecasting of a small segment of the population with large economic burden. It's based on a long-term... Read more »

Caspi, A., Houts, R., Belsky, D., Harrington, H., Hogan, S., Ramrakha, S., Poulton, R., & Moffitt, T. (2016) Childhood forecasting of a small segment of the population with large economic burden. Nature Human Behaviour, 5. DOI: 10.1038/s41562-016-0005  

  • December 19, 2016
  • 03:19 AM
  • 418 views

Gut barrier integrity meets blood-brain barrier integrity with autism in mind

by Paul Whiteley in Questioning Answers

"In the ASD [autism spectrum disorder] brain, there is an altered expression of genes associated with BBB [blood-brain barrier] integrity coupled with increased neuroinflammation and possibly impaired gut barrier integrity."Although pretty enthused to see research linking names like Anna Sapone, Tim Buie and Alessio Fasano in the recent paper published by Maria Fiorentino and colleagues [1] (open-access), I was slightly less impressed with the use of the term 'the ASD brain' ........ Read more »

Fiorentino, M., Sapone, A., Senger, S., Camhi, S., Kadzielski, S., Buie, T., Kelly, D., Cascella, N., & Fasano, A. (2016) Blood–brain barrier and intestinal epithelial barrier alterations in autism spectrum disorders. Molecular Autism, 7(1). DOI: 10.1186/s13229-016-0110-z  

  • December 17, 2016
  • 11:55 PM
  • 414 views

Some of the most beautiful emotions with no direct English words

by Usman Paracha in SayPeople

So, here is a vocabulary of some of the loveliest and beautiful emotions having no direct English translations:

Að jenna (Icelandic): Willingness or ability to continue the hard or boring tasks
Ah-un ((阿吽, Japanese): Unspoken communication between close friends
Cafune (Portuguese): Tenderly moving fingers through the hairs of a lover one
Fargin (Yiddish): To show or express pride and happiness at the success of others
Early morning

Gökotta (Swedish): Waking up early to hea........ Read more »

  • December 17, 2016
  • 05:51 AM
  • 359 views

Pregnancy influenza infection not linked to offspring autism

by Paul Whiteley in Questioning Answers

"There was no association between maternal influenza [flu] infection anytime during pregnancy and increased ASD [autism spectrum disorder] risk."So said the findings reported by Ousseny Zerbo and colleagues [1] continuing a research theme from this author (see here for example) looking at how various infections 'encountered' during critical periods of pregnancy may / may not impact on offspring autism risk. This time around the focus was on viral infections and in partic........ Read more »

  • December 16, 2016
  • 07:02 AM
  • 387 views

Power poses: It was such a nice idea but it  cannot be replicated (so far)

by Doug Keene in The Jury Room

Last week the Shark Tank television show was apparently shown during a time my DVR was trying to record another show for me. As I watched it, I was amused to see a couple of entrepreneurs whispering to each other to do “power poses” before they pitched to the shark-investors. I was amused, because I’d […]... Read more »

Bartlett, T. (2016) Power Poser: When big ideas go bad. Chronicle of Higher Education. info:/

  • December 16, 2016
  • 03:16 AM
  • 355 views

Non-febrile seizures in children with autism vs unaffected siblings

by Paul Whiteley in Questioning Answers

"Children with idiopathic ASD [autism spectrum disorder] are significantly more likely to have non-febrile seizures than their unaffected siblings, suggesting that non-febrile seizures may be ASD-specific."So said the findings from Lena McCue and colleagues [1] (open-access) continuing a research theme looking at one of the important 'comorbidities' that seems to be over-represented when it comes to a diagnosis of autism (see here). Idiopathic autism or ASD refers to autism as the........ Read more »

  • December 15, 2016
  • 02:59 AM
  • 414 views

ADHD, not autism, might count when it comes to 'comorbid psychiatric symptomatology'

by Paul Whiteley in Questioning Answers

A quote to begin this fairly brief post: "Our study concluded that higher levels of ADHD [attention-deficit hyperactivity disorder] severity-not ASD [autism spectrum disorder] severity-were associated with a higher prevalence of comorbid psychiatric symptomatology in school-age children with ASD. These findings may encourage clinicians to thoroughly assess ADHD symptomatology in ASD children to better inform treatment planning."That was the research bottom line reported by Ro........ Read more »

  • December 14, 2016
  • 03:07 AM
  • 384 views

Urinary metabolomics in autism turns up tryptophan (again)

by Paul Whiteley in Questioning Answers

"The tryptophan metabolic pathway collectively displays the largest perturbations in ASD [autism spectrum disorder]."So said the findings reported by Federica Gevi and colleagues [1] (open-access) who provide yet more 'metabolomic' data when it comes to autism to add to the already quite voluminous peer-reviewed matter on this topic (see here for example).Just in case you aren't analytical chemistry-saavy, metabolomics is basically the study of the various chemical fingerprints that th........ Read more »

  • December 13, 2016
  • 04:25 AM
  • 378 views

'My child is not talking'. Online concerns and internet-based screening for autism?

by Paul Whiteley in Questioning Answers

"Online communities are used as platforms by parents to verify developmental and health concerns related to their child."That was the starting point for the study results reported by Ben-Sasson & Yom-Tov [1] (open-access available here) who approached an increasingly important issue related to how the Internet and social media in particular, is fast becoming one of the 'go-to' options when it comes to parental concerns about their child's development and the question: could it be autism........ Read more »

  • December 12, 2016
  • 10:43 AM
  • 377 views

Simple Jury Persuasion: Why you don’t want your  trial videos to elicit awe from jurors 

by Doug Keene in The Jury Room

While you don’t want jurors to think your visual evidence was made by poorly trained technicians—here’s a study that tells us something counter-intuitive that you may find useful (we have). It may not make obvious sense, but you also don’t want jurors to be blown away (i.e., awed, in wonder, overwhelmed by the majesty of […]

Related posts:
Simple Jury Persuasion: Educating jurors about science may have no effect
Simple Jury Persuasion: Telling jurors where to look
Simple Jury Pe........ Read more »

Farias M, Newheiser AK, Kahane G, & de Toledo Z. (2013) Scientific faith: Belief in science increases in the face of stress and existential anxiety. Journal of Experimental Social Psychology, 49(6), 1210-1213. PMID: 24187384  

  • December 12, 2016
  • 04:37 AM
  • 360 views

Maternal immune activation (MIA) and Old World monkeys

by Paul Whiteley in Questioning Answers

Old World monkeys detailed in the title of this post, specifically refers to a type of animal called a rhesus macaque who were the 'participants' of choice as detailed in a recent study by Destanie Rose and colleagues [1] looking at a concept called maternal immune activation (MIA).Those who followed this blog down the years will no doubt have seen me discuss MIA before in the context of autism and/or schizophrenia (see here for example). The basic theory is that whilst in-utero a........ Read more »

  • December 10, 2016
  • 04:28 AM
  • 431 views

"Are we expecting too much from the extreme male brain theory of autism?"

by Paul Whiteley in Questioning Answers

The title of this post reflects the commentary published by Andrew Whitehouse [1] (open-access) discussing the meaning of the findings reported by Kung and colleagues [2] who quite categorically stated that there was: "No relationship between prenatal androgen exposure and autistic traits" in their study.OK, androgen exposure and psychology basically refers to the extreme male brain theory and autism which suggests that the so-called over-representation of autism in males is potentiall........ Read more »

  • December 9, 2016
  • 04:53 AM
  • 395 views

'Big data' Taiwan and schizophrenia risk

by Paul Whiteley in Questioning Answers

Today I bring the findings reported by Chou and colleagues [1] (open-access available here) to the blogging table and how the research might of the Taiwan National Health Insurance Database (NHIRD) brought it's 'big data' ("n = 23 422 955") to bear on the question: what is the risk of developing schizophrenia where one or more first-degree or other relatives are affected?The answer: "Having an affected co-twin, first-degree relative, second-degree relative, or spouse was associate........ Read more »

  • December 8, 2016
  • 05:12 PM
  • 570 views

Do We All Have Split Brains?

by Neuroskeptic in Neuroskeptic_Discover

When you're doing two things at once - like listening to the radio while driving - your brain organizes itself into two, functionally independent networks, almost as if you temporarily have two brains. That's according to a fascinating new study from University of Wisconsin-Madison neuroscientists Shuntaro Sasai and colleagues. It's called Functional split brain in a driving/listening paradigm



In referring to 'split brains' in their title, Sasai et al. are linking their work to the litera... Read more »

Sasai, S., Boly, M., Mensen, A., & Tononi, G. (2016) Functional split brain in a driving/listening paradigm. Proceedings of the National Academy of Sciences, 201613200. DOI: 10.1073/pnas.1613200113  

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