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  • November 30, 1999
  • 12:00 AM
  • 1,950 views

Interactive software tool for optimal sequence alignments with dynamic programming.

by suji george in Research Software and Book

ResearchBlogging.org

Dynamic programming (DP) is an optimizing strategy commonly used in various discipline in science. It is widely used in biology to calculate optimal alignment between pairs of protein or DNA sequences. DP is so important, that it is core of many software applications available today for sequence analysis. DP algorithm is essential topic in many undergraduate and graduate bioinformatics course. Although simple in formulation, DP is not that easy for students to learn.

S........ Read more »

  • November 30, 1999
  • 12:00 AM
  • 2,555 views

Cannabis law has no effect on cannabis use

by Neurobonkers in Neurobonkers

European Monitoring Centre for Drugs and Drug Addiction confirms that prohibition does not appear to effect levels of cannabis use in any way... Read more »

The european monitoring centre for drugs and drug addiction. (2011) The state of the drugs problem in Europe . Annual Report. info:/

  • November 30, 1999
  • 12:00 AM
  • 2,025 views

“Beware of Exercise” is a Sexy Headline

by nooffensebut in The Unsilenced Science

A new study that raised concerns about exercise should instead raise concerns about obesity.... Read more »

Claude Bouchard, Steven Blair, Timothy Church, Conrad Earnest, James Hagberg, Keijo Häkkinen, Nathan Jenkins, Laura Karavirta, William Kraus, Arthur Leon.... (2012) Adverse Metabolic Response to Regular Exercise: Is It a Rare or Common Occurrence?. PLOS One, 7(5). info:/10.1371/journal.pone.0037887

  • November 30, 1999
  • 12:00 AM
  • 2,306 views

Understanding PREDIMED and the Mediterranean diet: heart-healthy or hype?

by Kismet in Biogerontology and Health

I am going to discuss the failings of the PREDIMED study, real and imagined. I will do this in a Question & Answer style. Several questions are inspired by theheart.org and NEJM comments and even statements by the low fat "gurus", Essselstyn, Ornish, McDougall or Pritikin. It is no surprise they are up in arms after the study has been published. It threatens their livelihood.... Read more »

Estruch, R., Ros, E., Salas-Salvadó, J., Covas, M., Corella, D., Arós, F., Gómez-Gracia, E., Ruiz-Gutiérrez, V., Fiol, M., Lapetra, J.... (2013) Primary Prevention of Cardiovascular Disease with a Mediterranean Diet. New England Journal of Medicine, 368(14), 1279-1290. DOI: 10.1056/NEJMoa1200303  

  • November 30, 1999
  • 12:00 AM
  • 1,188 views

Interlukin 32 biomarker which predict relapse of mycobacterium tuberculosis

by B V Waghmare in HIV virus and antiretroviral drugs and antiAIDS vaccine research and developmets

Interlukin 32 a protien which is found in people which do test positie for mycobacterium tuberculosis infection but do not develop pulmonary disease, it is found that interlukin is important in killing micobacterium, thereby protect them from TB disease, this interleukin 32 can be used therapeutically in patients suffering with TB along with chemotherapy, which will enhance efficacy of anti tuberculosis chemo therapy... Read more »

B V Waghmare. (2014) Interlukin 32 biomarker that will predict relapse of tuberculosis infection and will be used in treatment of TB. http://www.medicalwebsite.org/2014/09/protein-that-protect-from-tb-infection.html. info:/

  • November 30, 1999
  • 12:00 AM
  • 1,389 views

...How to Fix Science

by Viputheshwar Sitaraman in Draw Science

(Part 2/2) However, we can fix science. [Infographic]... Read more »

Alberts, B., Kirschner, M., Tilghman, S., & Varmus, H. (2014) Rescuing US biomedical research from its systemic flaws. Proceedings of the National Academy of Sciences, 111(16), 5773-5777. DOI: 10.1073/pnas.1404402111  

  • November 30, 1999
  • 12:00 AM
  • 1,193 views

2014: The Year in Science

by Viputheshwar Sitaraman in Draw Science

The year in review: innovative discoveries and progress in all different fields of science. [Infographic]... Read more »

Qiu, X., Wong, G., Audet, J., Bello, A., Fernando, L., Alimonti, J., Fausther-Bovendo, H., Wei, H., Aviles, J., Hiatt, E.... (2014) Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp. Nature, 514(7520), 47-53. DOI: 10.1038/nature13777  

Obokata, H., Wakayama, T., Sasai, Y., Kojima, K., Vacanti, M., Niwa, H., Yamato, M., & Vacanti, C. (2014) Stimulus-triggered fate conversion of somatic cells into pluripotency. Nature, 505(7485), 641-647. DOI: 10.1038/nature12968  

Quintana, E., Barclay, T., Raymond, S., Rowe, J., Bolmont, E., Caldwell, D., Howell, S., Kane, S., Huber, D., Crepp, J.... (2014) An Earth-Sized Planet in the Habitable Zone of a Cool Star. Science, 344(6181), 277-280. DOI: 10.1126/science.1249403  

A.K. Geim, & K. S. Novoselov. (2010) The rise and rise of graphene. Nature Nanotechnology, 5(11), 755-755. DOI: 10.1038/nnano.2010.224  

  • November 30, 1999
  • 12:00 AM
  • 699 views

The Fatal Flaw in Trial of Continuous or Interrupted Chest Compressions during CPR

by Rogue Medic in Rogue Medic

This is not a study that has a valid control group to determine if there is any benefit from ventilation. There is no group that does not receive ventilations, so it is like a study of one type of blood-letting vs. another type of blood-letting with the researchers taking for granted that blood-letting does improve outcomes. That is not a problem if blood-letting actually improves outcomes.

Should we take it for granted that blood-letting improves outcomes and that the only hypothesis worth s........ Read more »

Nichol, G., Leroux, B., Wang, H., Callaway, C., Sopko, G., Weisfeldt, M., Stiell, I., Morrison, L., Aufderheide, T., Cheskes, S.... (2015) Trial of Continuous or Interrupted Chest Compressions during CPR. New England Journal of Medicine, 2147483647. DOI: 10.1056/NEJMoa1509139  

Alldredge BK,, Gelb AM,, Isaacs SM,, Corry MD,, Allen F,, Ulrich S,, Gottwald MD,, O’Neil N,, Neuhaus JM,, Segal MR,.... (2001) A Comparison of Lorazepam, Diazepam, and Placebo for the Treatment of Out-of-Hospital Status Epilepticus. New England Journal of Medicine, 345(25), 1860-1860. DOI: 10.1056/NEJM200112203452521  

  • November 30, 1999
  • 12:00 AM
  • 816 views

The geometry of consciousness is a multi-dimensional math trip

by amanda alvarez in It Ain't Magic

Amanda Alvarez writes about how neuroscientists are studying consciousness with mathematics.... Read more »

Oizumi M, Tsuchiya N, & Amari SI. (2016) Unified framework for information integration based on information geometry. Proceedings of the National Academy of Sciences of the United States of America, 113(51), 14817-14822. PMID: 27930289  

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