Other posts
- September 16, 2016
- 09:45 PM
- 181 views
Contiguity Effective for Deductive Inference
by Joshua Fisher in Text Savvy
Even if the benefits of retrieval practice were limited to improvements in recall (as prior research has demonstrated), such improvements do not stand in the way of improvements to higher-order reasoning, such as inference-making. (And shaping the path for students, such as improving informational contiguity can have a positive effect too.)... Read more »
Eglington, L., & Kang, S. (2016) Retrieval Practice Benefits Deductive Inference. Educational Psychology Review. DOI: 10.1007/s10648-016-9386-y
- September 12, 2016
- 06:19 AM
- 140 views
Strength In Numbers
by AG McCluskey in Zongo's Cancer Diaries
This post describes the concept behind combination therapies for cancer. Why are they needed? Why can they fail...?... Read more »
Komarova, N., & Boland, C. (2013) Cancer: Calculated treatment. Nature, 499(7458), 291-292. DOI: 10.1038/499291a
AG McCluskey. (2016) Strength in Numbers. Zongo's Cancer Diaries. info:/
- August 23, 2016
- 11:30 AM
- 232 views
Otulipenia – A New Inflammatory Disease
by Rita dos Santos Silva in United Academics
Researchers from the U.S. National Institutes of Health, working in collaboration with Turkish and British teams, discovered a new inflammatory disease.... Read more »
Zhou, Q., Wang, H., Schwartz, D., Stoffels, M., Park, Y., Zhang, Y., Yang, D., Demirkaya, E., Takeuchi, M., Tsai, W.... (2015) Loss-of-function mutations in TNFAIP3 leading to A20 haploinsufficiency cause an early-onset autoinflammatory disease. Nature Genetics, 48(1), 67-73. DOI: 10.1038/ng.3459
Elliott, P., Nielsen, S., Marco-Casanova, P., Fiil, B., Keusekotten, K., Mailand, N., Freund, S., Gyrd-Hansen, M., & Komander, D. (2014) Molecular Basis and Regulation of OTULIN-LUBAC Interaction. Molecular Cell, 54(3), 335-348. DOI: 10.1016/j.molcel.2014.03.018
- August 23, 2016
- 11:29 AM
- 210 views
Otulipenia – A New Inflammatory Disease
by Rita dos Santos Silva in United Academics
Researchers from the U.S. National Institutes of Health, working in collaboration with Turkish and British teams, discovered a new inflammatory disease.... Read more »
Zhou, Q., Wang, H., Schwartz, D., Stoffels, M., Park, Y., Zhang, Y., Yang, D., Demirkaya, E., Takeuchi, M., Tsai, W.... (2015) Loss-of-function mutations in TNFAIP3 leading to A20 haploinsufficiency cause an early-onset autoinflammatory disease. Nature Genetics, 48(1), 67-73. DOI: 10.1038/ng.3459
Elliott, P., Nielsen, S., Marco-Casanova, P., Fiil, B., Keusekotten, K., Mailand, N., Freund, S., Gyrd-Hansen, M., & Komander, D. (2014) Molecular Basis and Regulation of OTULIN-LUBAC Interaction. Molecular Cell, 54(3), 335-348. DOI: 10.1016/j.molcel.2014.03.018
- August 16, 2016
- 10:43 AM
- 183 views
The Angry Silence
by AG McCluskey in Zongo's Cancer Diaries
The experience of cancer patients has changed in many ways over the last 30 years. One massive improvement is that patients can talk about their diseases more freely.
And this may not just make them feel better, it might help to make them better too.......... Read more »
Lutgendorf, S., & Andersen, B. (2015) Biobehavioral approaches to cancer progression and survival: Mechanisms and interventions. American Psychologist, 70(2), 186-197. DOI: 10.1037/a0035730
MacMillan Cancer Support. (2016) Cancer: Then and Now. Diagnosis, treatment and aftercare from 1970–2016. MacMillan Cancer Support. info:/
- August 1, 2016
- 07:22 AM
- 232 views
Live Long & Prosper!
by AG McCluskey in Zongo's Cancer Diaries
Good news for cancer patients in the UK, as 10-year survival rates show big improvements.... Read more »
MacMillan Cancer Support. (2016) Cancer: Then and Now. Diagnosis, treatment and aftercare from 1970–2016. MacMillan Cancer Support. info:/
- July 30, 2016
- 07:30 PM
- 315 views
Problem Solving, Instruction: Chicken, Egg
by Joshua Fisher in Text Savvy
When research has more fairly compared PS-I with I-PS, it has concluded that, in general, the sequence doesn't matter all that much, though there are some positive trends on conceptual and transfer assessments for PS-I.... Read more »
Loibl, K., Roll, I., & Rummel, N. (2016) Towards a Theory of When and How Problem Solving Followed by Instruction Supports Learning. Educational Psychology Review. DOI: 10.1007/s10648-016-9379-x
- July 18, 2016
- 08:30 PM
- 393 views
Interleaving Study Is Not Interleaving Learning
by Joshua Fisher in Text Savvy
In the latest research, the authors found that a blocked schedule (presenting examples from one category at a time) outperformed an interleaved schedule (interspersing examples from all the categories) for category learning when the examples to be classified were more highly discriminable. This result was consistent across the two experiments in the study (p = 0.055 and p = 0.04). Importantly, however, although interleaving was a better strategy for learning categories of lower discriminability,........ Read more »
Noh, S., Yan, V., Bjork, R., & Maddox, W. (2016) Optimal sequencing during category learning: Testing a dual-learning systems perspective. Cognition, 23-29. DOI: 10.1016/j.cognition.2016.06.007
- June 17, 2016
- 07:11 AM
- 286 views
Computer Says No: Anti-cancer therapy and Autoimmune disease: Part II
by AG McCluskey in Zongo's Cancer Diaries
Scientists have been investigating the use of cancer therapies to treat Autoimmune disease. And the reasoning behind this? Treat the immune system like a computer program...... Read more »
Dr Harold L Atkins, MDcorrespondenceemail, Marjorie Bowman, MScN, David Allan, MD, Grizel Anstee, MD, Prof Douglas L Arnold, MD, Prof Amit Bar-Or, MD, Isabelle Bence-Bruckler, MD, Paul Birch, MLT, Prof Christopher Bredeson, MD, Jacqueline Chen, PhD, Prof . (2016) Immunoablation and autologous haemopoietic stem-cell transplantation for aggressive multiple sclerosis: a multicentre single-group phase 2 trial. The Lancet. info:/http://dx.doi.org/10.1016/S0140-6736(16)30169-6
Craciunescu, O., Steffey, B., Kelsey, C., Larrier, N., Paarz-Largay, C., Prosnitz, R., Chao, N., Chute, J., Gasparetto, C., Horwitz, M.... (2011) Renal Shielding and Dosimetry for Patients With Severe Systemic Sclerosis Receiving Immunoablation With Total Body Irradiation in the Scleroderma: Cyclophosphamide or Transplantation Trial. International Journal of Radiation Oncology*Biology*Physics, 79(4), 1248-1255. DOI: 10.1016/j.ijrobp.2010.05.036
AG McCluskey. (2016) Computer Says No. Zongo's Cancer Diaries. info:/
- May 27, 2016
- 12:10 PM
- 399 views
Enhance the Salience of Relevant Variables
by Joshua Fisher in Text Savvy
Performing the discrete mode of presentation test strongly enhances the salience of the relevant variable, perimeter, and somewhat decreases that of area. This enhancement supports appropriate solution strategies that lead to improved performance. This effect is robust and transfers to continuous mode of presentation for at least 10 days. In line with this conclusion, a student who performed the continuous test after the discrete one commented that, “It [continuous] was harder this time bu........ Read more »
Babai, R., Nattiv, L., & Stavy, R. (2016) Comparison of perimeters: improving students’ performance by increasing the salience of the relevant variable. ZDM, 48(3), 367-378. DOI: 10.1007/s11858-016-0766-z
- May 26, 2016
- 11:22 AM
- 364 views
Patent-ly Obvious...?
by AG McCluskey in Zongo's Cancer Diaries
Did you know that there may be bits of your own body that you don't own? That may be owned by someone else? No?? Then you need to know more about Gene Patenting...... Read more »
Rosenfeld, J., & Mason, C. (2013) Pervasive sequence patents cover the entire human genome. Genome Medicine, 5(3), 27. DOI: 10.1186/gm431
Liddicoat J, Whitton T, & Nicol D. (2015) Are the gene-patent storm clouds dissipating? A global snapshot. Nature biotechnology, 33(4), 347-52. PMID: 25850055
AG McCluskey. (2016) Patent-ly Obvious..?. Zongo's Cancer Diaries. info:/
- May 25, 2016
- 04:00 PM
- 498 views
Humiliation from stares are worse than tiny seats for obese air travelers
by Dr. Jekyll in Lunatic Laboratories
Feelings of shame and humiliation bother obese air passengers more than tight seat belts and tiny seats, according to a study published by Ben-Gurion University of the Negev (BGU) researchers. Participants interviewed for the study recounted the typical challenges they encounter while boarding, in-flight and deplaning.
... Read more »
Yaniv Poria, & Jeremy Beal. (2016) An Exploratory Study about Obese People’s Flight Experience . Journal of travel research. info:/10.1177/0047287516643416
- May 24, 2016
- 01:14 PM
- 442 views
Raising The Standards Of Open Access Journals
by Nesru Koroso in United Academics
The Directory of Open Access Journals bans dubious journals from its index.... Read more »
Baker, M. (2016) Open-access index delists thousands of journals. Nature. DOI: 10.1038/nature.2016.19871
Van Noorden, R. (2014) Open-access website gets tough. Nature, 512(7512), 17-17. DOI: 10.1038/512017a
- May 13, 2016
- 08:32 AM
- 386 views
The One And Only
by AG McCluskey in Zongo's Cancer Diaries
In future, the way that a patient's cancer is diagnosed and treated will be different. Every person is unique. And therefore every person's cancer is unique too...
Welcome to Personalised Medicine.... Read more »
Nik-Zainal, S., Davies, H., Staaf, J., Ramakrishna, M., Glodzik, D., Zou, X., Martincorena, I., Alexandrov, L., Martin, S., Wedge, D.... (2016) Landscape of somatic mutations in 560 breast cancer whole-genome sequences. Nature. DOI: 10.1038/nature17676
Morganella, S., Alexandrov, L., Glodzik, D., Zou, X., Davies, H., Staaf, J., Sieuwerts, A., Brinkman, A., Martin, S., Ramakrishna, M.... (2016) The topography of mutational processes in breast cancer genomes. Nature Communications, 11383. DOI: 10.1038/ncomms11383
AG McCluskey. (2016) The One And Only. Zongo's Cancer Diaries. info:/
- May 12, 2016
- 12:30 PM
- 432 views
The Pantanal Diaries III: Ready to Mix
by Chiara Civardi in United Academics
Emerge into Brazil’s swamp, with Chiara and the Wildlife Conservation Society.... Read more »
Rodrigo Luiz Simas de Aguiar, & Keny Marques Lima. (2012) A arte rupestre em cavernas da região noroeste de Mato Grosso do Sul discussões preliminares. Espeleo-Tema, 23(2). info:/
- May 10, 2016
- 06:36 AM
- 435 views
Psychosis: Understanding The Symptoms
by Pieter Carrière in United Academics
Dealing with psychotic patients takes more than looking at their diagnostic labels.... Read more »
Heering, H., van Haren, N., & Derks, E. (2013) A two-factor structure of first rank symptoms in patients with a psychotic disorder. Schizophrenia Research, 147(2-3), 269-274. DOI: 10.1016/j.schres.2013.04.032
Heering, H., Koevoets, G., Koenders, L., Machielsen, M., Meijer, C., Kubota, M., de Nijs, J., Cahn, W., Hulshoff Pol, H., de Haan, L.... (2015) Structural MRI Differences between Patients with and without First Rank Symptoms: A Delusion?. Frontiers in Psychiatry. DOI: 10.3389/fpsyt.2015.00107
Nelson B, Whitford TJ, Lavoie S, & Sass LA. (2014) What are the neurocognitive correlates of basic self-disturbance in schizophrenia? Integrating phenomenology and neurocognition: Part 2 (aberrant salience). Schizophrenia research, 152(1), 20-7. PMID: 23863772
Perälä, J., Suvisaari, J., Saarni, S., Kuoppasalmi, K., Isometsä, E., Pirkola, S., Partonen, T., Tuulio-Henriksson, A., Hintikka, J., Kieseppä, T.... (2007) Lifetime Prevalence of Psychotic and Bipolar I Disorders in a General Population. Archives of General Psychiatry, 64(1), 19. DOI: 10.1001/archpsyc.64.1.19
- May 6, 2016
- 08:47 AM
- 401 views
Fight The Good Fight?
by AG McCluskey in Zongo's Cancer Diaries
A lot of cancer research funding in the UK comes from charities. But how do they raise the funds? And does the end justify the means?... Read more »
O'Toole, L., Nurse, P., & Radda, G. (2003) An analysis of cancer research funding in the UK. Nature Reviews Cancer, 3(2), 139-143. DOI: 10.1038/nrc994
AG McCluskey. (2016) Fight The Good Fight?. Zongo's Cancer Diaries. info:/
- April 29, 2016
- 11:02 AM
- 589 views
Bringing ‘Dirty’ Mice Into Labs Opens A World Of Possibilities
by Rita dos Santos Silva in United Academics
Treating immune disorders might have gotten easier with a new mouse model.... Read more »
Beura, L., Hamilton, S., Bi, K., Schenkel, J., Odumade, O., Casey, K., Thompson, E., Fraser, K., Rosato, P., Filali-Mouhim, A.... (2016) Normalizing the environment recapitulates adult human immune traits in laboratory mice. Nature, 532(7600), 512-516. DOI: 10.1038/nature17655
Mestas, J., & Hughes, C. (2004) Of Mice and Not Men: Differences between Mouse and Human Immunology. The Journal of Immunology, 172(5), 2731-2738. DOI: 10.4049/jimmunol.172.5.2731
Shultz, D. (2016) Can ‘dirty mice’ save animal research?. Science. DOI: 10.1126/science.aaf4153
Reardon, S. (2016) Dirty room-mates make lab mice more useful. Nature, 532(7599), 294-295. DOI: 10.1038/532294a
- April 29, 2016
- 05:41 AM
- 354 views
Review, Refine, Redesign
by AG McCluskey in Zongo's Cancer Diaries
Drug Discovery, Part III
How is a an Initial Hit optimised and turned into a Lead Compound?... Read more »
Hughes, J., Rees, S., Kalindjian, S., & Philpott, K. (2011) Principles of early drug discovery. British Journal of Pharmacology, 162(6), 1239-1249. DOI: 10.1111/j.1476-5381.2010.01127.x
AG McCluskey. (2016) Review, Refine, Redesign. Zongo's Cancer Diaries. info:/
- April 26, 2016
- 10:42 AM
- 371 views
You Scratch My Back
by AG McCluskey in Zongo's Cancer Diaries
Where does the idea of a scientist as a crazed loner come from. Let's work together!... Read more »
Brown, R., Deletic, A., & Wong, T. (2015) Interdisciplinarity: How to catalyse collaboration. Nature, 525(7569), 315-317. DOI: 10.1038/525315a
AG McCluskey. (2016) You Scratch My Back.. Zongo's Cancer Diaries. info:/
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