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  • April 18, 2015
  • 05:22 AM
  • 12 views

Autistic traits in adult-onset psychiatric disorders?

by Paul Whiteley in Questioning Answers

"To conclude, the presentation of ALTs [autistic-like traits/symptoms] at the sub-threshold or threshold level may be closely associated with BPD [bipolar disorder] and SZ [schizophrenia]."That was the conclusion reached in the paper by Junko Matsuo and colleagues [1] (open-access here) based on their analysis of nearly 300 adults aged between 25-59 years including those diagnosed with "MDD [major depressive disorder], n=125; bipolar disorder, n=56; schizophrenia,&n........ Read more »

Matsuo J, Kamio Y, Takahashi H, Ota M, Teraishi T, Hori H, Nagashima A, Takei R, Higuchi T, Motohashi N.... (2015) Autistic-Like Traits in Adult Patients with Mood Disorders and Schizophrenia. PloS one, 10(4). PMID: 25838109  

  • April 17, 2015
  • 07:47 PM
  • 21 views

Study links brain anatomy, academic achievement, and family income

by Dr. Jekyll in Lunatic Laboratories

Many years of research have shown that for students from lower-income families, standardized test scores and other measures of academic success tend to lag behind those of wealthier students. Well now a new study offers another dimension to this so-called “achievement gap”After imaging the brains of high- and low-income students, they found that the higher-income students had thicker brain cortex in areas associated with visual perception and knowledge accumulation.... Read more »

Allyson Mackey et al. (2015) Students’ Family Income Linked With Brain Anatomy, Academic Achievement. Psychological Science. info:/

  • April 17, 2015
  • 03:56 PM
  • 15 views

Artificial blood vessel lets researchers assess clot removal devices

by Dr. Jekyll in Lunatic Laboratories

For the first time, researchers have created an in vitro, live-cell artificial vessel that can be used to study both the application and effects of devices used to extract life-threatening blood clots in the brain. The artificial vessel could have significant implications for future development of endovascular technologies, including reducing the need for animal models to test new devices or approaches.... Read more »

  • April 17, 2015
  • 03:52 AM
  • 28 views

Higher cancer mortality rates associated with mental illness

by Paul Whiteley in Questioning Answers

The findings reported by Steve Kisely and colleagues [1] were of some interest recently and their assertion that despite cancer incidence being "the same as the general population for most psychiatric disorders" or even slightly reduced when a diagnosis of schizophrenia was for example received, mortality due to cancer was "increased in psychiatric patients."Such findings were based on their examination of: "Mental health records [that] were linked with cancer registrations and death r........ Read more »

  • April 16, 2015
  • 02:39 PM
  • 38 views

Could maple syrup help cut use of antibiotics?

by Dr. Jekyll in Lunatic Laboratories

Another reason to have those waffles… well maybe. Researchers have found that a concentrated extract of maple syrup makes disease-causing bacteria more susceptible to antibiotics. In an ever increasing antibiotic resistant world, this news is almost as sweet as the syrup (okay no more bad puns). The findings suggest that combining maple syrup extract with common antibiotics could increase the microbes’ susceptibility, leading to lower antibiotic usage.... Read more »

  • April 16, 2015
  • 10:32 AM
  • 37 views

What is Neurofeedback Training for ADHD?

by William Yates, M.D. in Brain Posts

There are a variety of behavioral strategies for treating the attention and activity components of attention deficit hyperactivity disorder (ADHD).One of these strategies is known as neurofeedback. A recent study in the journal Pediatrics found evidence for effectiveness of in-school neurofeedback for ADHD in a randomized controlled trial.In this trial, 104 children between the ages of 7 and 11 years of age were randomized to one of three research arms: in-school neurofeedback, cognitive th........ Read more »

  • April 16, 2015
  • 08:40 AM
  • 35 views

Outbreak! Time To Review The Origins Of Vaccination

by Bill Sullivan in The 'Scope

Imagine a world without vaccines. The recent measles outbreak in Disneyland is providing us with a very small taste of what such a world would be like. Today on THE 'SCOPE, we go back in time to the age of smallpox and review the fascinating discoveries that led Edward Jenner to invent vaccination, a process that has saved countless lives.... Read more »

Babkin, I., & Babkina, I. (2015) The Origin of the Variola Virus. Viruses, 7(3), 1100-1112. DOI: 10.3390/v7031100  

  • April 16, 2015
  • 05:21 AM
  • 40 views

Paternal sperm epigenetic differences and offspring autism risk

by Paul Whiteley in Questioning Answers

"These data suggest that epigenetic differences in paternal sperm may contribute to autism risk in offspring."So said the preliminary study results published by Jason Feinberg and colleagues [1]  (open-access) looking at "paternal semen biosamples obtained from an autism spectrum disorder (ASD) enriched-risk pregnancy cohort, the Early Autism Risk Longitudinal Investigation (EARLI) cohort." Researchers analysed 44 semen samples to ascertain whether DNA methylation differences - one typ........ Read more »

Jason I Feinberg, Kelly M Bakulski, Andrew E Jaffe, Rakel Tryggvadottir, Shannon C Brown, Lynn R Goldman, Lisa A Croen, Irva Hertz-Picciotto, Craig J Newschaffer, M Daniele Fallin.... (2015) Paternal sperm DNA methylation associated with early signs of autism risk in an autism-enriched cohort. International Journal of Epidemiology. info:/10.1093/ije/dyv028

  • April 15, 2015
  • 03:45 PM
  • 53 views

Brain development suffers from lack of fish oil fatty acids

by Dr. Jekyll in Lunatic Laboratories

While being inundated with advertisements directed at moms to be, skeptical parents should question the supposed health benefits of anything being sold. However, while recent reports question whether fish oil supplements support heart health, scientists have found that the fatty acids they contain are vitally important to the developing brain. Meaning there might actually be truth in advertising -- this time at least.... Read more »

  • April 15, 2015
  • 03:31 AM
  • 33 views

Maternal diabetes and offspring autism risk... again

by Paul Whiteley in Questioning Answers

"In this large, multiethnic clinical cohort of singleton children born at 28 to 44 weeks’ gestation, exposure to maternal GDM [gestational diabetes mellitus] diagnosed by 26 weeks’ gestation was associated with risk of ASD [autism spectrum disorder] in offspring."That was the conclusion reached by Anny Xiang and colleagues [1] (open-access) following their analysis of some 3300 children diagnosed with ASD as part of a wider cohort of over 300,000 children "born in 19........ Read more »

Xiang, A., Wang, X., Martinez, M., Walthall, J., Curry, E., Page, K., Buchanan, T., Coleman, K., & Getahun, D. (2015) Association of Maternal Diabetes With Autism in Offspring. JAMA, 313(14), 1425. DOI: 10.1001/jama.2015.2707  

  • April 14, 2015
  • 03:18 PM
  • 47 views

Watch out Atkins: Over eating fatty foods can alter your muscle metabolism

by Dr. Jekyll in Lunatic Laboratories

More bad news on the obesity front and strangely enough, on the popular diet front too — at least for diets like atkins. New research shows that even short term high-fat diets can change your metabolism. So while you might think that you can get away with eating fatty foods for a few days without it making any significant changes to your body, think again.... Read more »

Anderson, A., Haynie, K., McMillan, R., Osterberg, K., Boutagy, N., Frisard, M., Davy, B., Davy, K., & Hulver, M. (2015) Early skeletal muscle adaptations to short-term high-fat diet in humans before changes in insulin sensitivity. Obesity, 23(4), 720-724. DOI: 10.1002/oby.21031  

  • April 14, 2015
  • 12:48 PM
  • 42 views

Global Temperature Rise and Human Health - How is the World Coping?

by Sarah Stephen in An ecological oratorio

Global temperatures have been on the rise since the Industrial Age due to human activity such as the emissions of greenhouse gases from fossil fuel burning, large-scale deforestation, expansion of urban areas where vegetation cover is replaced by artificial heat retaining materials such as asphalt and concrete, some agricultural practices, and waste management activities. Data from the National Climatic Data Centre that  maintains the world's largest climate data archive indicate that the a........ Read more »

  • April 14, 2015
  • 08:45 AM
  • 23 views

Malaria diagnosis with RDT MAbs

by SS in Scientific scrutiny

Examining the business of patenting MAbs against epitopes described before and the need for caution in using MAbs against epitopes reported to be deleted in different parts of the world... Read more »

  • April 14, 2015
  • 04:08 AM
  • 42 views

Immune signature in ME/CFS detected in cerebrospinal fluid

by Paul Whiteley in Questioning Answers

The research tag-team that is Mady Hornig and Ian Lipkin are fairly frequently mentioned on this blog. If it's not to do with their studies in autism research (see here for a recent mention) it is with their ground-breaking work looking at chronic fatigue syndrome / myalgic encephalomyelitis (CFS/ME) in mind (see here for example).Indeed their latest paper [1] extends some recent findings (see here) on immune involvement in relation to CFS/ME [2] with a focus on examinations in cerebrospinal flu........ Read more »

  • April 13, 2015
  • 09:29 PM
  • 30 views

High Cost-Sharing Policies For Physician Care May Not Benefit Chronically Ill Patients

by Marie Benz in MedicalResearch.com

MedicalResearch.com Medical Research Interviews and News
MedicalResearch.com Interview with: Haichang Xin, PhD Department of Health Care Organization and policy School of Public Health University of Alabama at Birmingham MedicalResearch: What is the background for this study? Dr. Xin: Since high cost-sharing policies can reduce both needed … Continue reading →
The post High Cost-Sharing Policies For Physician Care May Not Benefit Chronically Ill Patients appeared first on MedicalRese........ Read more »

MedicalResearch.com Interview with: Haichang Xin, PhD. (2015) High Cost-Sharing Policies For Physician Care May Not Benefit Chronically Ill Patients. MedicalResearch.com. info:/

  • April 13, 2015
  • 03:37 PM
  • 63 views

The placebome: Where genetics and the placebo effect meet

by Dr. Jekyll in Lunatic Laboratories

Placebos have helped to ease symptoms of illness for centuries and have been a fundamental component of clinical research to test new drug therapies for more than 70 years. But why some people respond to placebos and others do not remains under debate.... Read more »

Kathryn T. Hall et al. (2015) Genetics and the placebo effect: the placebome. Trends in Molecular Medicine. info:/10.1016/j.molmed.2015.02.009

  • April 13, 2015
  • 10:34 AM
  • 50 views

An unusual form of diabetes may be caused by drinking arsenic-contaminated water

by Megan Cartwright in Science-Based Writing

Like a careless criminal, even small amounts of toxic arsenic leave telltale fingerprints on victims’ bodies—although these fingerprints are different if the victim as Type 2 Diabetes, scientists report. And arsenic has many potential victims: more than 200 million people worldwide … Continue reading →... Read more »

Martin, E., Gonzalez-Horta, C., Rager, J., Bailey, K., Sanchez-Ramirez, B., Ballinas-Casarrubias, L., Ishida, M., Gutierrez-Torres, D., Hernandez Ceron, R., Viniegra Morales, D.... (2015) Metabolomic Characteristics of Arsenic-Associated Diabetes in a Prospective Cohort in Chihuahua, Mexico. Toxicological Sciences, 144(2), 338-346. DOI: 10.1093/toxsci/kfu318  

  • April 13, 2015
  • 10:22 AM
  • 55 views

Treating Insomnia in Children with ADHD

by William Yates, M.D. in Brain Posts

Insomnia commonly complicates the clinical presentation and treatment in children with ADHD.Stimulant therapy may provide significant relief for daytime attention and hyperactivity symptoms. However, stimulants do not appear to help with comorbid insomnia. In fact, stimulant therapy may cause more problems with insomnia in ADHD.Behavioral treatments are known to be effective in children without ADHD. Now we have a recently published study showing the effectiveness of behavioral treatment of inso........ Read more »

  • April 13, 2015
  • 01:38 AM
  • 49 views

Interoception and body awareness in autism

by Paul Whiteley in Questioning Answers

"Interoception: the sense of the physiological condition of the body" [1].This was an important concept detailed in the paper by Lisa Fiene and Charlotte Brownlow [2] with autism in mind. Looking at how adults diagnosed with an ASD (autism spectrum disorder) "interpret elements of the interoceptive sense, which includes thirst, hunger, temperature, satiety" researchers questioned those on the spectrum (n=74) and asymptomatic controls (n=228) with "self-reported perceptions of body awareness........ Read more »

  • April 12, 2015
  • 01:36 PM
  • 58 views

Neuronal disorders and energy metabolism

by Dr. Jekyll in Lunatic Laboratories

Scientists in Japan have have discovered how nerve cells adjust to low energy environments during the brain's growth process. Their study may one day help find treatments for nerve cell damage and neurodegenerative disorders such as Alzheimer's and Parkinson's diseases.... Read more »

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