Health posts
- May 6, 2013
- 09:08 AM
- 67 views
The Benefits Of Being ill
by Katja Keuchenius in United Academics
A lot has changed in the human body since our ancestors walked around on bare feet. We have less hair, we got bigger and we live longer, for example. But we’re still being haunted by some very stubborn diseases that survived the evolution. How is that possible?... Read more »
van Mens, T., Levi, M., & Middeldorp, S. (2013) Evolution of Factor V Leiden. Thrombosis and Haemostasis, 110(1). DOI: 10.1160/TH13-02-0115
- May 6, 2013
- 07:38 AM
- 92 views
It’s Not the Sugar That Rots Teeth
by Andrew Porterfield in United Academics
You’ve been hearing it for years; don’t eat too much sugar, because sugar rots your teeth. It turns out that sugar isn’t the real culprit behind tooth decay. Researchers, looking at the bacteria responsible for dental cavities, had found a molecule that can stop these common dental problems.
Jose Cordova, a Yale University researcher, and Erich Astudillo, from the University of Chile, identified the new molecule, called Keep32, that kills the Streptococcus Mutans bacteria an........ Read more »
Pacey, L. (2012) Chile creates cavity killer. BDJ, 213(5), 202-202. DOI: 10.1038/sj.bdj.2012.793
- May 6, 2013
- 05:01 AM
- 92 views
Is it impossible to drown yourself?
by Anouk Vleugels in United Academics
Kind of a morbid question, but apparently one that is on many people’s minds. Suicide by drowning is definitely not impossible, although it is not the easiest method. Due to the body’s natural tendency to come up for air, drowning attempts are most likely to succeed in deep waters.... Read more »
Byard, R., Houldsworth, G., James, R., & Gilbert, J. (2001) Characteristic Features of Suicidal Drownings. The American Journal of Forensic Medicine and Pathology, 22(2), 134-138. DOI: 10.1097/00000433-200106000-00005
- May 6, 2013
- 04:36 AM
- 78 views
The ESSENCE of autism comorbidity?
by Paul Whiteley in Questioning Answers
Like Charlie Bucket looking through the sweet shop window at the delicious chocolates produced by the workforce of a certain Mr Willy Wonka (the candyman no less), I am always quite interested in the goings-on at the IMFAR autism research conference. The candyman can... @ Wikipedia This year (2013) proved to be a bit of a vintage, as once again the great and the good presented their Wonka bars of autism research; thus hinting at the direction of future autism research and what y........ Read more »
Höglund Carlsson, L., Norrelgen, F., Kjellmer, L., Westerlund, J., Gillberg, C., & Fernell, E. (2013) Coexisting Disorders and Problems in Preschool Children with Autism Spectrum Disorders. The Scientific World Journal, 1-6. DOI: 10.1155/2013/213979
- May 5, 2013
- 11:30 AM
- 73 views
Chromosomes, Sex, and Sleep
by Allison in Dormivigilia
We have differentiated between chromosomal versus hormonal influences on normal sleep and sleep rebounds in hermaphroditic mice. The neural mechanisms are TBD, however. ... Read more »
Ehlen, J., Hesse, S., Pinckney, L., & Paul, K. (2013) Sex Chromosomes Regulate Nighttime Sleep Propensity during Recovery from Sleep Loss in Mice. PLoS ONE, 8(5). DOI: 10.1371/journal.pone.0062205
- May 5, 2013
- 05:57 AM
- 97 views
More on 'Bugs as Drugs'
by Christen Rune Stensvold in Blastocystis Parasite Blog
A follow-up on Carl Zimmer's post in "Phenomena" (National Geographic) on 'Bugs as Drugs'.... Read more »
Hyman P, Atterbury R, & Barrow P. (2013) Fleas and smaller fleas: virotherapy for parasite infections. Trends in microbiology. PMID: 23540830
van Nood E, Vrieze A, Nieuwdorp M, Fuentes S, Zoetendal EG, de Vos WM, Visser CE, Kuijper EJ, Bartelsman JF, Tijssen JG.... (2013) Duodenal infusion of donor feces for recurrent Clostridium difficile. The New England journal of medicine, 368(5), 407-15. PMID: 23323867
Weinstock JV. (2012) Autoimmunity: The worm returns. Nature, 491(7423), 183-5. PMID: 23135449
- May 5, 2013
- 01:21 AM
- 104 views
Reversal of Gray hair and Vitiligo at the root level
by Usman Paracha in SayPeople
Main Points:
Gray hair comes as a result of hydrogen peroxide accumulation in the hair follicles and the newly reported topical UVB-activated, pseudocatalase (PC-KUS) can help against the accumulation of hydrogen peroxide at the root level.
Published in:
The FASEB Journal
Study Further:
"To date, it is beyond any doubt that the sudden loss of the inherited skin and localized hair color can affect those individuals in many fundamental ways," Karin U. Schallreuter, M.D., s........ Read more »
Schallreuter, K., Salem, M., Holtz, S., & Panske, A. (2013) Basic evidence for epidermal H2O2/ONOO--mediated oxidation/nitration in segmental vitiligo is supported by repigmentation of skin and eyelashes after reduction of epidermal H2O2 with topical NB-UVB-activated pseudocatalase PC-KUS. The FASEB Journal. DOI: 10.1096/fj.12-226779
- May 4, 2013
- 03:30 AM
- 76 views
Surgery following self-injurious behaviour
by Paul Whiteley in Questioning Answers
Discussions on self-injurious behaviour (SIB) or auto-aggression are not normally for the faint-hearted.Indeed, as I intimated on a previous post on SIB and autism, when such behaviours are witnessed in children and young adults - even older adults, one does wonder what the effects might be not only on the person themselves but also on a parent or a sibling as they watch their own flesh and blood banging their head on a wall or pulling their hair out or trying to gouge their eyes out. I can't pu........ Read more »
Sisk RA, Motley WW 3rd, Yang MB, & West CE. (2013) Surgical outcomes following repair of traumatic retinal detachments in cognitively impaired adolescents with self-injurious behavior. Journal of pediatric ophthalmology and strabismus, 50(1), 20-6. PMID: 23061560
- May 3, 2013
- 11:32 AM
- 83 views
Taking Two Antibiotics for Quick Recovery?
by Geetanjali Yadav in United Academics
Did you ever take two or more antibiotics in order to get rid of a disease? New research in PLOS Biology suggests that this is not a wise thing to do. Drug resistant bacteria grow faster than their weaker counter parts when resources are limiting and many antibiotics are consumed.... Read more »
Pena-Miller R, Laehnemann D, Jansen G, Fuentes-Hernandez A, Rosenstiel P, Schulenburg H, & Beardmore R. (2013) When the most potent combination of antibiotics selects for the greatest bacterial load: the smile-frown transition. PLoS biology, 11(4). PMID: 23630452
- May 3, 2013
- 05:23 AM
- 96 views
New Insight into Meat vs Fish Debate
by Mark Fonseca Rendeiro in United Academics
The benefits of taking fish oil and the harm caused by eating red meat, these two nutritional nuggets of wisdom have been passed around so much over the past few decades, we rarely stop to ask if they really do what people claim they do.
This month, two new papers on the subject of fish and meat have come forward from the University of Western Australia. The first examines the real impact of taking fish oil supplements on the diets of obese people.... Read more »
Wong, A., Chan, D., Ooi, E., Ng, T., Watts, G., & Barrett, P. (2013) Omega-3 fatty acid ethyl ester supplementation decreases very-low-density lipoprotein triacylglycerol secretion in obese men. Clinical Science, 125(1), 45-51. DOI: 10.1042/CS20120587
Koeth, R., Wang, Z., Levison, B., Buffa, J., Org, E., Sheehy, B., Britt, E., Fu, X., Wu, Y., Li, L.... (2013) Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis. Nature Medicine. DOI: 10.1038/nm.3145
- May 2, 2013
- 04:30 PM
- 78 views
Will IV Oxygen Save Lives?
by Rogue Medic in Rogue Medic
Intravenous oxygen delivery that works?
Maybe temporary oxygenation, but not yet.
Will this change the approach to CICV (Can’t Intubate, Can’t Ventilate) patients?
No, but it may change the approach to CICO (Can’t Intubate, Can’t Oxygenate) patients.
The distinction is important. ... Read more »
Kheir, J., Scharp, L., Borden, M., Swanson, E., Loxley, A., Reese, J., Black, K., Velazquez, L., Thomson, L., Walsh, B.... (2012) Oxygen Gas-Filled Microparticles Provide Intravenous Oxygen Delivery. Science Translational Medicine, 4(140), 140-140. DOI: 10.1126/scitranslmed.3003679
- May 2, 2013
- 02:48 PM
- 116 views
Sex, hormones, and the microbiome
by sedeer in Inspiring Science
The microbiome — the kilogram of microbes that each of us carries around — has been shown to be involved …Continue reading »... Read more »
Markle JG, Frank DN, Mortin-Toth S, Robertson CE, Feazel LM, Rolle-Kampczyk U, von Bergen M, McCoy KD, Macpherson AJ, & Danska JS. (2013) Sex differences in the gut microbiome drive hormone-dependent regulation of autoimmunity. Science (New York, N.Y.), 339(6123), 1084-8. PMID: 23328391
- May 2, 2013
- 10:53 AM
- 82 views
UF researchers develop ‘nanotrain’ for targeted cancer drug transport
by Perikis Livas in Tracing Knowledge
University of Florida researchers have developed a “DNA nanotrain” that fast-tracks its payload of cancer-fighting drugs and bioimaging agents to tumor cells deep within the body. The nanotrain’s ability to cost-effectively deliver high doses of drugs to precisely targeted cancers and other medical maladies without leaving behind toxic nano-clutter has been the elusive Holy Grail for scientists studying the teeny-tiny world of DNA nanotechnology.... Read more »
Lindy McCollum-Brounley. (2013) UF researchers develop ‘nanotrain’ for targeted cancer drug transport. University of Florida News. info:/
- May 2, 2013
- 10:38 AM
- 144 views
Redefining Mental Disorders as Brain Disorders: TED Talk of Thomas Insel
by William Yates, M.D. in Brain Posts
Components of Brain Limbic SystemAdvances in the diagnosis and treatment of brain disorders like bipolar disorder, schizophrenia and autism are a public health priority.Dr. Thomas Insel, director at NIMH recently presented a TED talk that emphasized the need to rethink how we conceptualize and study these types of disorders. He argues for a need to redefine mental disorders as brain disorders. Advances in brain research tools are likely to provide improvements in early diagnosis and ........ Read more »
Collins, P., Insel, T., Chockalingam, A., Daar, A., & Maddox, Y. (2013) Grand Challenges in Global Mental Health: Integration in Research, Policy, and Practice. PLoS Medicine, 10(4). DOI: 10.1371/journal.pmed.1001434
Insel, T. (2011) A bridge to somewhere. Translational Psychiatry, 1(4). DOI: 10.1038/tp.2011.4
- May 2, 2013
- 07:51 AM
- 39 views
M'eye New Workout Reset: eye work as active recovery
by mc in begin to dig (b2d)
hypothesis: Use of recovery periods between weight sets can be used for vision work as form of active recovery to improve strength, vision and recovery technique. ... Read more »
Andersson H, Raastad T, Nilsson J, Paulsen G, Garthe I, & Kadi F. (2008) Neuromuscular fatigue and recovery in elite female soccer: effects of active recovery. Medicine and science in sports and exercise, 40(2), 372-80. PMID: 18202563
Davis WJ, Wood DT, Andrews RG, Elkind LM, & Davis WB. (2008) Elimination of delayed-onset muscle soreness by pre-resistance cardioacceleration before each set. Journal of strength and conditioning research / National Strength , 22(1), 212-25. PMID: 18296978
Micklewright, D., Beneke, R., Gladwell, V., & Sellens, M. (2003) BLOOD LACTATE REMOVAL USING COMBINED MASSAGE AND ACTIVE RECOVERY. Medicine , 35(Supplement 1). DOI: 10.1097/00005768-200305001-01755
Suzuki M, Umeda T, Nakaji S, Shimoyama T, Mashiko T, & Sugawara K. (2004) Effect of incorporating low intensity exercise into the recovery period after a rugby match. British journal of sports medicine, 38(4), 436-40. PMID: 15273179
- May 2, 2013
- 03:53 AM
- 59 views
Treatments Still Aren’t the Right Dose for Kids
by Andrew Porterfield in United Academics
It was an unprecedented move: U.S. Health and Human Services Secretary Kathleen Sibelius overruled the FDA when she announced that Teva Pharmaceutical’s Plan B One Step contraceptive pill would not be available to women under 17 years of age. ... Read more »
Funk RS, Brown JT, & Abdel-Rahman SM. (2012) Pediatric pharmacokinetics: human development and drug disposition. Pediatric clinics of North America, 59(5), 1001-16. PMID: 23036241
- May 1, 2013
- 12:29 PM
- 93 views
Pericytes can be used for muscle regeneration
by beredim in Stem Cells Freak
Researchers from the Wake Forest Baptist Medical Center (WFBMC) announced today that they may have unveiled some of the mechanisms involved in obesity, diabetes mellitus type 2, muscular dystrophy and other diseases associated with fat replacing muscle tissue, causing it to weaken and degenerate. Their findings have the potential to lead to new therapies for the aforementioned diseases, say the researchers.Read More... Read more »
Birbrair, A., Zhang, T., Wang, Z., Messi, M., Enikolopov, G., Mintz, A., & Delbono, O. (2013) Role of Pericytes in Skeletal Muscle Regeneration and Fat Accumulation. Stem Cells and Development, 2147483647. DOI: 10.1089/scd.2012.0647
- May 1, 2013
- 11:54 AM
- 90 views
Advances In Parkinson's Disease Treatment: Part II
by William Yates, M.D. in Brain Posts
Globus Pallidus Region of Brain Targeted in DBS in YellowIn a previous post, I summarized some of the highlights of a recent review of Parkinson's disease management by the German neurologists Pedrosa and Timmerman.The first post can be located here and was limited to the drug treatment of the motor symptoms of Parkinson's disease.In part II, I want to focus on deep brain stimulation and the treatment of non-motor symptoms.The authors of the review note the following key points regarding deep br........ Read more »
Pedrosa, D., & Timmermann, . (2013) Review: management of Parkinson's disease. Neuropsychiatric Disease and Treatment, 321. DOI: 10.2147/NDT.S32302
- May 1, 2013
- 09:17 AM
- 83 views
Video Tip of the Week: My Cancer Genome
There are a lot of cancer database resources out there. Most of the ones we’ve focused on have been the data repository types. TCGA, ICGC, CaBIG, COSMIC, Cancer Genome Workbench, UCSC Cancer Genomic Browser, and of course big repositories like GEO. Researchers will need these sources of data to locate key alterations in cancer cells [...]... Read more »
Swanton, C. (2012) My Cancer Genome: a unified genomics and clinical trial portal. The Lancet Oncology, 13(7), 668-669. DOI: 10.1016/S1470-2045(12)70312-1
Yeh, P., Chen, H., Andrews, J., Naser, R., Pao, W., & Horn, L. (2013) DNA-Mutation Inventory to Refine and Enhance Cancer Treatment (DIRECT): A Catalog of Clinically Relevant Cancer Mutations to Enable Genome-Directed Anticancer Therapy. Clinical Cancer Research, 19(7), 1894-1901. DOI: 10.1158/1078-0432.CCR-12-1894
- May 1, 2013
- 03:52 AM
- 83 views
Depression is not much common in U.S. as said
by Usman Paracha in SayPeople
Main point:
Researcher has found that over-diagnosis and over-treatment of depression is common in Americans.
Journal:
Psychotherapy and Psychosomatics
Study Further:
"Depression over-diagnosis and over-treatment is common in the U.S. and frankly the numbers are staggering," said Ramin J. Mojtabai, PhD, author of the study and an associate professor with the Bloomberg School's Department of Mental Health.
Researcher, in this study, worked on 5,639 participants wi........ Read more »
Mojtabai, R. (2013) Clinician-Identified Depression in Community Settings: Concordance with Structured-Interview Diagnoses. Psychotherapy and Psychosomatics, 82(3), 161-169. DOI: 10.1159/000345968
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