Post List

Health posts

(Modify Search »)

  • January 25, 2017
  • 02:56 AM
  • 388 views

Autism and visual impairment reviewed

by Paul Whiteley in Questioning Answers

Of the various autism science journals out there in peer-reviewed (La-La!) land, one journal in particular is really starting to grow on me: [The] Review Journal of Autism and Developmental Disorders.I like this journal because it is basically systematic review and meta-analysis heaven when it comes to the quite voluminous autism research literature and seems to publish some real gems (see here for example).Another paper from this journal caught my eye recently by Maggie Butchart and colleagues ........ Read more »

Butchart, M., Long, J., Brown, M., McMillan, A., Bain, J., & Karatzias, T. (2017) Autism and Visual Impairment: a Review of the Literature. Review Journal of Autism and Developmental Disorders. DOI: 10.1007/s40489-016-0101-1  

  • January 24, 2017
  • 04:49 AM
  • 364 views

Fatty acids 'for autism'? Meta-analysis says probably not but...

by Paul Whiteley in Questioning Answers

"Because of the limited number of included studies and small sample sizes, no firm conclusions can be drawn. However, the limited data currently available suggest that ω-3 FA [fatty acid] supplementation does not enhance the performance of children with ASD [autism spectrum disorder]."Those were the conclusions reached in the systematic review and meta-analysis paper published by Andrea Horvath and colleagues [1] looking at the collected peer-reviewed literature on the topic up t........ Read more »

  • January 23, 2017
  • 10:59 AM
  • 399 views

Processing Speed Cognition in Elderly: Clinical Trial

by William Yates, M.D. in Brain Posts

Processing speed declines significantly with age and contributes to impairment and disability in old age.There is little known about whether age-related processing speed decline can be slowed with interventionA recent clinical trial by a Japanese group targeted processing speed training in a group of 72 elderly.This study found significant effects for a daily 15 minute processing speed training game over 4 weeks.In contrast to a control group, the intervention group found specific improvement in........ Read more »

  • January 23, 2017
  • 02:45 AM
  • 384 views

Autism diagnoses (and diagnostic stability) in Germany

by Paul Whiteley in Questioning Answers

"From 2006 to 2012, the prevalence of autism spectrum disorder diagnoses in 0- to 24-year-olds increased from 0.22% to 0.38%."That was one of the details included in the rather interesting paper by Christian Bachmann and colleagues [1] who provided some introductory information on the the trends in autism diagnoses in Germany. I say 'introductory information' because it appears that autism or autism spectrum disorder (ASD) has not exactly received the research attention in Germany that it p........ Read more »

Christian J Bachmann, Bettina Gerste, & Falk Hoffmann. (2016) Diagnoses of autism spectrum disorders in Germany: Time trends in administrative prevalence and diagnostic stability. Autism: International Journal of Research . info:/10.1177/1362361316673977

  • January 21, 2017
  • 03:25 AM
  • 417 views

"no evidence that the probiotic formulation is effective in treating low mood"

by Paul Whiteley in Questioning Answers

I'm a great believer in balance when it comes to this blog and its content. As enthusiastic as I might be about a particular topic or topics, I don't want to lose sight of the fact that peer-reviewed science is a messy business and often filled with contrary findings.With 'contrary' in mind, I want to talk today about a paper by Amy Romijn and colleagues [1] detailing the results of a double-blind, randomised, placebo-controlled trial of a probiotic mix which contained "freeze-dried L. helv........ Read more »

  • January 20, 2017
  • 03:10 AM
  • 384 views

Diagnosing ME/CFS the machine learning way?

by Paul Whiteley in Questioning Answers

In today's post I want to draw your attention to the findings reported by Diana Ohanian and colleagues [1] (open-access available here) talking about "the use of machine learning to further explore the unique nature"of various conditions/labels including those typically headed under the label of chronic fatigue syndrome / myalgic encephalomyelitis (CFS/ME).Including one 'Jason LA' on the authorship list, researchers set about looking at "what key symptoms differentiate Myalgic Encephalomyelitis ........ Read more »

  • January 19, 2017
  • 03:04 AM
  • 404 views

The correlates of regressive autism

by Paul Whiteley in Questioning Answers

"A more homogeneous subgroup with regression between 18 and 36 months (n = 48) had higher rates of intellectual disability, epilepsy, and special education, more socially restrictive educational settings, and more severe ASD [autism spectrum disorder] communication deficits and schizophrenia spectrum symptoms than non-regressed youth (n = 136)."So said the findings reported by Kenneth Gadow and colleagues [1] taking on one of the more important issues in relation to autism: dev........ Read more »

  • January 18, 2017
  • 03:13 AM
  • 415 views

Physical activity levels and autism (again)

by Paul Whiteley in Questioning Answers

"Adolescents with ASD [autism spectrum disorder] spent less time in MVPA [moderate and vigorous physical activity] compared to TD [typically developing] adolescents (29 min/day vs. 50 min/day, p < 0.001) and fewer met the Physical Activity Guidelines for Americans (14 vs. 29%, p > 0.05)."So said the study results published by Heidi Stanish and colleagues [1] adding yet more to another growth autism research area - physical activity and exercise - ........ Read more »

  • January 17, 2017
  • 04:28 AM
  • 414 views

Vitamin D supplementation and self-perceived fatigue

by Paul Whiteley in Questioning Answers

"Vitamin D treatment significantly improved fatigue in otherwise healthy persons with vitamin D deficiency."Supplementation details, described in the paper by Albina Nowak and colleagues [1] (open-access available here), were a single dose of 100,000 IU [international units] of vitamin D or a placebo (mannitol) administered to 120 adult participants who presented with "fatigue and vitamin D deficiency (serum 25(OH)D < 20 μg/L)." This was a double-blind trial and self-perceived fatigue ........ Read more »

Nowak A, Boesch L, Andres E, Battegay E, Hornemann T, Schmid C, Bischoff-Ferrari HA, Suter PM, & Krayenbuehl PA. (2016) Effect of vitamin D3 on self-perceived fatigue: A double-blind randomized placebo-controlled trial. Medicine, 95(52). PMID: 28033244  

  • January 16, 2017
  • 03:11 AM
  • 433 views

Autism-like traits and/or autism elevated in psychosis

by Paul Whiteley in Questioning Answers

"Rates of ASD [autism spectrum disorder] and ASD traits are elevated in a psychosis population."The paper by Debbie Kincaid and colleagues [1] provides yet more [short] blogging material pertinent to the increasing interest in how psychosis may be yet another comorbidity over-represented when it comes to autism (see here) and vice-versa. I know this is another topic that has to be treated with some caution in terms of concepts like stigma but more discussions - science discussions........ Read more »

  • January 14, 2017
  • 04:35 AM
  • 478 views

No significant difference in circulating cytokines in autism vs controls?

by Paul Whiteley in Questioning Answers

"As compared with 54 typically developing controls, we found no evidence of differences in the blood profile of immune mediators supportive of active systemic inflammation mechanisms in participants with autism."That was the unexpected research bottom-line published by Carlos Pardo and colleagues [1] (open-access) examining whether various immune-related chemicals - "cytokines, chemokines, or growth factors in serum and cerebrospinal fluid" - might be linked to autism following longitudinal........ Read more »

  • January 13, 2017
  • 03:13 AM
  • 417 views

Exercise as an intervention for anxiety?

by Paul Whiteley in Questioning Answers

"Our data suggest that exercise is more effective than control at reducing anxiety symptoms."So said the meta-analysis published by Brendan Stubbs and colleagues [1] who surveyed the peer-reviewed literature "investigating the benefits of exercise compared to usual treatment or control conditions in people with an anxiety and/or stress-related disorders." From the 6 randomised, controlled trials found "from inception until December 2015" exercise (various types of exercise regime) did seem to ha........ Read more »

  • January 13, 2017
  • 02:40 AM
  • 375 views

Acute coronary syndrome on Friday the 13th: a case for re-organising services?

by Rogue Medic in Rogue Medic

"However, patients admitted on five day/number combinations were 20-30% more likely to survive at 13 years. These findings could be explained by subgroup analysis inflation of the type I error, although supernatural causes merit further investigation.[1]"

No. Supernatural causes do not merit further investigation, at least, not based on anything in this paper.

The authors used Friday the 13th as their "normal" date for comparison with every other date, but the outcomes ........ Read more »

Protty, M., Jaafar, M., Hannoodee, S., & Freeman, P. (2016) Acute coronary syndrome on Friday the 13th: a case for re-organising services?. The Medical Journal of Australia, 205(11), 523-525. DOI: 10.5694/mja16.00870  

  • January 12, 2017
  • 04:28 AM
  • 374 views

On autism risk and immigrant status

by Paul Whiteley in Questioning Answers

"Fifteen studies suggest a higher prevalence rate of ASDs [autism spectrum disorder] among children of immigrants in comparison to native children."Those fifteen studies formed a large part of the seventeen studies included in the review by Rafal Kawa and colleagues [1] who set out to look at the collected peer-reviewed literature on the topic of the "prevalence and risk for ASD in Europe among immigrants and ethnic minorities." Carried out as part of a European Union (EU) initiative t........ Read more »

Kawa R, Saemundsen E, Lóa Jónsdóttir S, Hellendoorn A, Lemcke S, Canal-Bedia R, García-Primo P, & Moilanen I. (2016) European studies on prevalence and risk of autism spectrum disorders according to immigrant status-a review. European journal of public health. PMID: 28013245  

  • January 11, 2017
  • 03:24 AM
  • 401 views

"the patient improved significantly when a gluten-free diet was started"

by Paul Whiteley in Questioning Answers

The quote making up the title of this post comes from the case report described by Albino J Oliveira-Maia and colleagues [1] talking yet again about how coeliac disease - the archetypal autoimmune condition where dietary gluten is the baddie - may have effects well beyond just the physical.Describing the experiences of a woman who was admitted to a psychiatry inpatient unit on the basis of "suicidal behaviours" who also "developed an agitated catatonic state", a mix of "antidepressants, anx........ Read more »

Oliveira-Maia AJ, Andrade I, & Barahona-Corrêa JB. (2016) Case of coeliac disease presenting in the psychiatry ward. BMJ case reports. PMID: 28003229  

  • January 10, 2017
  • 09:00 AM
  • 383 views

The Rise Of Superbugs: How Bacteria Defeat Antibiotics

by Bill Sullivan in The 'Scope

Mechanisms of antibiotic resistance... Read more »

Blair, J., Webber, M., Baylay, A., Ogbolu, D., & Piddock, L. (2014) Molecular mechanisms of antibiotic resistance. Nature Reviews Microbiology, 13(1), 42-51. DOI: 10.1038/nrmicro3380  

  • January 10, 2017
  • 03:19 AM
  • 358 views

PACE trial recovery data and chronic fatigue syndrome

by Paul Whiteley in Questioning Answers

PACE mentioned in the title of this post refers to the PACE trial [1] which concluded that: "CBT [cognitive behaviour therapy] and GET [graded exercise therapy] can safely be added to SMC [specialist medical care] to moderately improve outcomes for chronic fatigue syndrome, but APT [adaptive pacing therapy] is not an effective addition."The recent paper by Carolyn Wilshire and colleagues [2] who drew on "relevant normative data and other research" continue........ Read more »

  • January 9, 2017
  • 04:26 AM
  • 439 views

T. gondii and OCD?

by Paul Whiteley in Questioning Answers

It's been a while since I've talked about Toxoplasma gondii on this blog; the parasite that more than most, has been linked with all-manner of different psychiatric labels (see here for example). Although still the topic of some discussion, I'm swayed towards the possibility that there may be some important *associations* to be seen when it comes to this survivor and human behaviour(s) outside of just making rats attracted to cat urine (see here) to improve reproduction chances.Indeed, in t........ Read more »

  • January 7, 2017
  • 04:15 AM
  • 400 views

ADHD and vitamin levels

by Paul Whiteley in Questioning Answers

"ADHD [attention-deficit hyperactivity disorder] patients were overrepresented in the group with low levels of some vitamins, possibly indicative of inadequate dietary intake of these micronutrients in a subgroup of patients. It is important to identify these patients in dietary intervention trials of ADHD."So said the study findings reported by Elisabeth Toverud Landaas and colleagues [1] (open-access) providing some potentially important data on how nutritional factors might int........ Read more »

Landaas ET, Aarsland TI, Ulvik A, Halmøy A, Ueland PM, & Haavik J. (2016) Vitamin levels in adults with ADHD. BJPsych open, 2(6), 377-384. PMID: 27990293  

  • January 6, 2017
  • 06:09 AM
  • 456 views

Particulate matter exposure and autism risk systematically reviewed?

by Paul Whiteley in Questioning Answers

"To conclude, the evidence from the studies allows us to conclude that there is an association between PM [particulate matter] exposure and ASD [autism spectrum disorder] whose strength varies according to the particle size studied with the association with PM2.5 and diesel PM being stronger."Although probably not great sentence structure to begin a post with a conclusion, the 'bottom line' reported by María Morales-Suárez-Varela and colleagues [1] summarises the curre........ Read more »

join us!

Do you write about peer-reviewed research in your blog? Use ResearchBlogging.org to make it easy for your readers — and others from around the world — to find your serious posts about academic research.

If you don't have a blog, you can still use our site to learn about fascinating developments in cutting-edge research from around the world.

Register Now

Research Blogging is powered by SRI Technology.

To learn more, visit http://selfregulationinstitute.org/.