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  • November 30, 1999
  • 12:00 AM
  • 2,023 views

Let’s Get Cellular: Meth Metabolism

by Dirk Hanson in Addiction Inbox

We know from the work of Nora Volkow and others that meth abusers have chronically low levels of dopamine D2 receptors in their brains. But what is going on in the rest of the body when methamphetamine addiction is running full force?... Read more »

Sun, L., Li, H., Seufferheld, M., Walters, K., Margam, V., Jannasch, A., Diaz, N., Riley, C., Sun, W., Li, Y.... (2011) Systems-Scale Analysis Reveals Pathways Involved in Cellular Response to Methamphetamine. PLoS ONE, 6(4). DOI: 10.1371/journal.pone.0018215  

  • November 30, 1999
  • 12:00 AM
  • 2,984 views

Friday Weird Science GUEST POST: The distance between your testicles and your anus, 'taint unimportant

by Allie Wilkinson in OH, FOR THE LOVE OF SCIENCE!

A Friday Weird Science guest post on Neurotic Physiology takes a humorous look at anogenital distance and its implication for fertility in adult males.... Read more »

  • November 30, 1999
  • 12:00 AM
  • 1,938 views

HIV vaccine research: Protein which train B cells for production of antibodies against HIV which successfully neutralize HIV

by B V Waghmare in HIV virus and antiretroviral drugs and antiAIDS vaccine research and developmets

HIV virus rapidly undergoes mutation, which is main hurdle in developing vaccine against HIV.There is a region on HIV virus which shows less variations, called as Cd4 binding site ,therefore a protein which stimulate antibody formation against this region can be developed and used as a vaccine.
Researchers at Vaccine Research Center (VRC) and the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health have studied genes which code for such proteins which can........ Read more »

B V Waghmare. (2011) HIV vaccine development : Proteins which trains B Cells for production of antibodies which successfully neutralize HIV by binding with it . http://bvwaghmare.blogspot.com. info:/(DOI/arXiv/etc.)

  • November 30, 1999
  • 12:00 AM
  • 2,559 views

Cannabis law has no effect on cannabis use

by Neurobonkers in Neurobonkers

European Monitoring Centre for Drugs and Drug Addiction confirms that prohibition does not appear to effect levels of cannabis use in any way... Read more »

The european monitoring centre for drugs and drug addiction. (2011) The state of the drugs problem in Europe . Annual Report. info:/

  • November 30, 1999
  • 12:00 AM
  • 1,907 views

Babies Are Healthier When There Is a Dog at Home: Research

by United Academics in United Academics

New research published in Pediatrics suggests that children living with a dog are significantly healthier than those living without it. The researchers followed up 397 Finnish children, asking their parents to fill in weekly questionnaires about their health until they were 1 year old. Scientists believe that this is so because dog contact helps the babies build up their immune system.... Read more »

Eija Bergroth, Sami Remes, Juha Pekkanen, Timo Kauppila, Gisela Büchele, & Leea Keski-Nisula. (2012) Respiratory Tract Illnesses During the First Year of Life: Effect of Dog and Cat Contacts. Pediatrics. info:/10.1542/peds.2011-2825

  • November 30, 1999
  • 12:00 AM
  • 2,021 views

Working Late in Pregnancy May Be as Bad for the Baby as Smoking: Research

by United Academics in United Academics

Researchers at the University of Essex, in the UK, have found that babies born to women who kept working during their eighth month of pregnancy tend to weight 230g less than those born to mothers who stopped working. The harm was bigger when the women had lower levels of education, while there was no harm at all when they were younger than 24.... Read more »

  • November 30, 1999
  • 12:00 AM
  • 1,511 views

Working Late in Pregnancy May Be as Bad for the Baby as Smoking: Research

by United Academics in United Academics

Researchers at the University of Essex, in the UK, have found that babies born to women who kept working during their eighth month of pregnancy tend to weight 230g less than those born to mothers who stopped working. The harm was bigger when the women had lower levels of education, while there was no harm at all when they were younger than 24.... Read more »

  • November 30, 1999
  • 12:00 AM
  • 1,930 views

3 surprising insights on how food cravings relate to other desires in everyday life

by Ellen van Kleef in Food Intake Control

What is harder to resist? Checking your Twitter or Facebook account at work or eating a delicious, but fattening snack when you try to watch your calories? Both are inner conflicts, best described as 'I really want to do this, but I should not'.

This blog post looks at the paper of Wilhelm Hofmann, Kathlees Vohs and Roy Baummeister who recently tried to answer these questions in their Everyday Temptation Study. ... Read more »

Hofmann W, Baumeister RF, Förster G, & Vohs KD. (2012) Everyday temptations: an experience sampling study of desire, conflict, and self-control. Journal of personality and social psychology, 102(6), 1318-35. PMID: 22149456  

  • November 30, 1999
  • 12:00 AM
  • 2,686 views

Impulsive snacking at the checkout counter: nudging consumers towards healthier 'grab-and-go'-snacks

by Ellen van Kleef in Food Intake Control

Tempting snacks placed right near the checkout counter can be hard to resist. Even though you know buying one is not in your best interest, they catch attention. These high-profit 'grap-and-go' snacks are particularly hard to ignore at the end of a shopping trip after making dozens of decisions. This blog post discusses a recent paper in which we studied whether assortment structure and accessibility of healthier snacks influences consumer choices. ... Read more »

  • November 30, 1999
  • 12:00 AM
  • 1,938 views

Drinking is Healthy

by Anton Power in BioMed Weekly

Response to absurd assertion that alcoholic beverages are simply vices.... Read more »

Frozza, R., Bernardi, A., Hoppe, J., Meneghetti, A., Matté, A., Battastini, A., Pohlmann, A., Guterres, S., & Salbego, C. (2013) Neuroprotective Effects of Resveratrol Against Aβ Administration in Rats are Improved by Lipid-Core Nanocapsules. Molecular Neurobiology. DOI: 10.1007/s12035-013-8401-2  

  • November 30, 1999
  • 12:00 AM
  • 1,767 views

Vaccines: Myths and Realities

by Anton Power in BioMed Weekly

Summary of common myths and why they are wrong.... Read more »

De Wals P, Deceuninck G, Toth E, Boulianne N, Brunet D, Boucher RM, Landry M, & De Serres G. (2012) Risk of Guillain-Barré syndrome following H1N1 influenza vaccination in Quebec. JAMA : the Journal of the American Medical Association, 308(2), 175-81. PMID: 22782419  

  • November 30, 1999
  • 12:00 AM
  • 2,310 views

Understanding PREDIMED and the Mediterranean diet: heart-healthy or hype?

by Kismet in Biogerontology and Health

I am going to discuss the failings of the PREDIMED study, real and imagined. I will do this in a Question & Answer style. Several questions are inspired by theheart.org and NEJM comments and even statements by the low fat "gurus", Essselstyn, Ornish, McDougall or Pritikin. It is no surprise they are up in arms after the study has been published. It threatens their livelihood.... Read more »

Estruch, R., Ros, E., Salas-Salvadó, J., Covas, M., Corella, D., Arós, F., Gómez-Gracia, E., Ruiz-Gutiérrez, V., Fiol, M., Lapetra, J.... (2013) Primary Prevention of Cardiovascular Disease with a Mediterranean Diet. New England Journal of Medicine, 368(14), 1279-1290. DOI: 10.1056/NEJMoa1200303  

  • November 30, 1999
  • 12:00 AM
  • 1,312 views

The Science of Sleep

by Amy Swanston in Antisense Science

Feeling tired? I know I am. But what is it that makes us feel like we need to sleep? And what keeps us awake?
Within our bodies, a lot of systems work antagonistically to maintain homeostasis - that is, one action opposes another, keeping balance. There are two important forces that we use to control sleep: our sleep drive and our alerting signal. As the day goes on, the drive to sleep becomes greater and greater, so our alerting signal has to increase at the same rate to keep us awake. S........ Read more »

  • November 30, 1999
  • 12:00 AM
  • 1,833 views

When chronic pain is there before surgery

by Bronwyn Thompson in Healthskills: Skills for Healthy Living

People with chronic pain present a special risk for surgeons, anaesthetists, nurses and the rehabilitation team working with them after surgery. Surgery is, after all, “planned trauma”, and a sensitive nervous system is going to be even more sensitive after a surgical insult – even when that surgery is intended to reduce pain.... Read more »

  • November 30, 1999
  • 12:00 AM
  • 1,484 views

How eating several smaller sized chocolates makes you look greedy and impulsive: the unit size effect of indulgent food

by Ellen van Kleef in Food Intake Control

Imagine you are offered a package full of delicious chocolates. Would the size of the pieces of chocolate influences how much you eat?

Yes, it does matter. This blog post is about the unit size effect of indulgent food and why consumers eat less with smaller unit sizes.
... Read more »

  • November 30, 1999
  • 12:00 AM
  • 1,540 views

Heroin’s Anthrax Problem

by Rebecca Kreston in BODY HORRORS

Anthrax is a deadly disease with high rates of morbidity and mortality. Because it is, thankfully, also quite rare, it is relatively easy to track its whereabouts and going-ons when an outbreak occurs. Typically, outbreaks of anthrax have been traced to groups of people involved in high-risk activities involving grazing animals and their byproducts: anthrax favors shepherds, butchers, wool-sorters, leather workers, and even the odd drum-playing hippies. In 2009, however, an outbreak upended this........ Read more »

  • November 30, 1999
  • 12:00 AM
  • 1,736 views

How sex-engineered prawns can be used to fight deadly parasite

by This Science is Crazy! in This Science Is Crazy!

Scientists float the idea of introducing male-only prawn stocks to Senegal river to control spread of snails which act as vector for blood flukes... Read more »

  • November 30, 1999
  • 12:00 AM
  • 1,192 views

Interlukin 32 biomarker which predict relapse of mycobacterium tuberculosis

by B V Waghmare in HIV virus and antiretroviral drugs and antiAIDS vaccine research and developmets

Interlukin 32 a protien which is found in people which do test positie for mycobacterium tuberculosis infection but do not develop pulmonary disease, it is found that interlukin is important in killing micobacterium, thereby protect them from TB disease, this interleukin 32 can be used therapeutically in patients suffering with TB along with chemotherapy, which will enhance efficacy of anti tuberculosis chemo therapy... Read more »

B V Waghmare. (2014) Interlukin 32 biomarker that will predict relapse of tuberculosis infection and will be used in treatment of TB. http://www.medicalwebsite.org/2014/09/protein-that-protect-from-tb-infection.html. info:/

  • November 30, 1999
  • 12:00 AM
  • 1,194 views

2014: The Year in Science

by Viputheshwar Sitaraman in Draw Science

The year in review: innovative discoveries and progress in all different fields of science. [Infographic]... Read more »

Qiu, X., Wong, G., Audet, J., Bello, A., Fernando, L., Alimonti, J., Fausther-Bovendo, H., Wei, H., Aviles, J., Hiatt, E.... (2014) Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp. Nature, 514(7520), 47-53. DOI: 10.1038/nature13777  

Obokata, H., Wakayama, T., Sasai, Y., Kojima, K., Vacanti, M., Niwa, H., Yamato, M., & Vacanti, C. (2014) Stimulus-triggered fate conversion of somatic cells into pluripotency. Nature, 505(7485), 641-647. DOI: 10.1038/nature12968  

Quintana, E., Barclay, T., Raymond, S., Rowe, J., Bolmont, E., Caldwell, D., Howell, S., Kane, S., Huber, D., Crepp, J.... (2014) An Earth-Sized Planet in the Habitable Zone of a Cool Star. Science, 344(6181), 277-280. DOI: 10.1126/science.1249403  

A.K. Geim, & K. S. Novoselov. (2010) The rise and rise of graphene. Nature Nanotechnology, 5(11), 755-755. DOI: 10.1038/nnano.2010.224  

  • November 30, 1999
  • 12:00 AM
  • 928 views

PD-L1 expression associates with non-inactivated VHL ccRCC

by Joana Guedes in BHD Research Blog

The loss of the of the tumor suppressor gene VHL and the subsequent deregulation of VHL/HIF/VEGF signalling are known to play a role in development of clear cell renal cell carcinoma (ccRCC). Renal tumours associated with BHD syndrome are histologically diverse and include a percentage of ccRCC (Pavlovich et al., 2002). Anti-angiogenic therapies targeting the VHL/HIF/VEGF pathway have emerged in past years (Rini et al., 2006) but the development of resistance to these therapeutic agents is leadi........ Read more »

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