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  • May 24, 2013
  • 05:26 AM
  • 3 views

Specialized Bat Tongue Helps it Drink

by Andrew Porterfield in United Academics

Bats need to eat a lot to keep flying. So, the more efficiently they can take in food, the better. for the nectar-eating bat Glossophaga soricina, this has meant the evolution of a sophisticated tongue. ... Read more »

Harper CJ, Swartz SM, & Brainerd EL. (2013) Specialized bat tongue is a hemodynamic nectar mop. Proceedings of the National Academy of Sciences of the United States of America. PMID: 23650382  

  • May 24, 2013
  • 04:00 AM
  • 2 views

Video Interview: Professor Vera Krymskaya – University of Pennsylvania, USA

by Lizzie Perdeaux in BHD Research Blog

This week we would like to introduce you to the work of Professor Vera Krymskaya, Associate Professor of Medicine at the University of Pennsylvania Perelman School of Medicine. Professor Krymskaya’s primary research interest is how signalling pathways cause disease when … Continue reading →... Read more »

  • May 23, 2013
  • 07:15 PM
  • 12 views

Molecular visualization tools - Survey and practical tips

by Ragothamanyennamalli in Getting to know Structural Bioinformatics

What would be like to teach a class or describe someone about a protein, without visualizing its structure? Boring is one word that pops in my mind. I vividly remember the professor drawing two blobs touching each other, to describe protein-protein interaction, while explaining it either on the blackboard or on the transparencies of a over-head projector. Those were the days! Tracing back nearly 60 years back, when John Kendrew showed everyone a coiled mess, it has fueled every scientist's ........ Read more »

Craig, P., Michel, L., & Bateman, R. (2013) A survey of educational uses of molecular visualization freeware. Biochemistry and Molecular Biology Education, 41(3), 193-205. DOI: 10.1002/bmb.20693  

  • May 23, 2013
  • 04:24 PM
  • 18 views

All lobsters are mortal

by Zen Faulkes in NeuroDojo

This appeared earlier today on the Facebook feed I Fucking Love Science:




Argh!

I remember seeing a shark documentary as a kid, hosted by Burgess Meredith, if I remember correctly. It made the same basic claim about great white sharks: too big to have predators, nobody had ever seen them die except by accident or by human hands, blah blah blah, therefore “some have suggested” they are immortal.

That I can remember the end of the show all these years later shows you what a terrific close........ Read more »

Klapper Wolfram, Kühne Karen, Singh Kumud K, Heidorn Klaus, Parwaresch Reza, & Krupp Guido. (1998) Longevity of lobsters is linked to ubiquitous telomerase expression. FEBS Letters, 439(1-2), 143-146. DOI: 10.1016/S0014-5793(98)01357-X  

  • May 23, 2013
  • 03:37 PM
  • 14 views

Researchers Turn a Smartphone into a Biosensor

by Jason Carr in Wired Cosmos

University of Illinois at Urbana-Champaign researchers have developed a cradle and app for the iPhone that uses the phone’s built-in camera and processing power as a biosensor to detect toxins, proteins, bacteria, viruses and other molecules. Having such sensitive biosensing capabilities in the field could enable on-the-spot tracking of groundwater contamination, combine the phone’s GPS … Read More →... Read more »

Gallegos, D., Long, K., Yu, H., Clark, P., Lin, Y., George, S., Nath, P., & Cunningham, B. (2013) Label-free biodetection using a smartphone. Lab on a Chip, 13(11), 2124. DOI: 10.1039/C3LC40991K  

  • May 23, 2013
  • 01:00 PM
  • 8 views

Microbial Misadventures: Exploits in Botulism & Pruno In Our Prison Population

by Rebecca Kreston in BODY HORRORS

Drinking pruno is a risky endeavor, both in terms of its offense to culinary sensibilities and to one's health. However, turned stomachs are not the only hazard here; you may add a desire to avoid botulism to your list of reasons to shy away from you'r mates latest batch of prison hooch. The soil-dwelling bacterium Clostridium botulinum can contaminate fruits and veggies, and, in warm, oxygen-deprived conditions, produces the neuroparalytic toxin botulinum. Even more wholesome DIY ende........ Read more »

Centers for Disease Control and Prevention (CDC). (2013) Notes from the field: botulism from drinking prison-made illicit alcohol - Arizona, 2012. MMWR. Morbidity and mortality weekly report, 62(5), 88. PMID: 23388552  

  • May 23, 2013
  • 12:44 PM
  • 8 views

If you chew that mRNA, you must make a new one!

by Gal Haimovich in Green Fluorescent Blog

Gene expression is very complex.  My paper, which was published in Cell today, just shows that it is more complicated than previously realized. Traditionally, eukaryotic gene expression is divided into five steps: Transcription (mRNA synthesis): this step is subdivided into … Continue reading →... Read more »

Haimovich, G., Medina, D., Causse, S., Garber, M., Millán-Zambrano, G., Barkai, O., Chávez, S., Pérez-Ortín, J., Darzacq, X., & Choder, M. (2013) Gene Expression Is Circular: Factors for mRNA Degradation Also Foster mRNA Synthesis. Cell, 153(5), 1000-1011. DOI: 10.1016/j.cell.2013.05.012  

  • May 23, 2013
  • 09:21 AM
  • 17 views

Should you worry about vitamin D deficiency? Maybe. Or maybe not.

by EE Giorgi in CHIMERAS

Since my last blog post, where I shared my thoughts on BRCA1, BRCA2, and preventive mastectomies, I've been asked what else can a woman do to reduce her risk of breast cancer. I've heard a big deal about vitamin D, so I did a bit of research on the matter. As a disclaimer, I should tell you up front that, though many correlations between vitamin D deficiency and cancer risk have been found, just as many have been refuted or found inconclusive. You can read more about it on the wikipedia page.Wha........ Read more »

  • May 23, 2013
  • 08:28 AM
  • 11 views

It’s great to be a woman scientist; it’s challenging to be a woman scientist

by Stephanie Swift in mmmbitesizescience

I recently volunteered to help organise an event run by the Canadian Science Policy Centre that looked at the status of women in science and technology. To be frank, I was mightily fearful about participating in such an event. I … Continue reading →... Read more »

Wenneras C, & Wold A. (1997) Nepotism and sexism in peer-review. Nature, 387(6631), 341-3. PMID: 9163412  

  • May 23, 2013
  • 04:33 AM
  • 17 views

Big data for autism and the promise of newborn bloodspots

by Paul Whiteley in Questioning Answers

An episode of the BBC program Horizon on 'Big Data' recently caught my attention. The content was a fascinating insight into how we are living in a data-rich age and how trawling/mining/dredging such data has the ability to advance medicine, predict crime and even make someone a few quid/dollars/euros on the stock market.Gone (data) fishing @ Wikipedia  I'm a big believer in big data. In particular how, with the right sources, technology, techniques and people, big data might be able t........ Read more »

Mizejewski GJ, Lindau-Shepard B, & Pass KA. (2013) Newborn screening for autism: in search of candidate biomarkers. Biomarkers in medicine, 7(2), 247-60. PMID: 23547820  

  • May 22, 2013
  • 02:55 PM
  • 24 views

Offshore Drilling Helps Microbiologists Study Life on Earth and Beyond

by dailyfusion in The Daily Fusion

Offshore drilling is often discussed in terms of its positive effect on the economy and the potential risks it carries for the environment. There’s, however, another side to offshore drilling, one that is less often talked about.... Read more »

  • May 22, 2013
  • 02:01 PM
  • 54 views

Marijuana and Diabetes: Does Pot Make You Thin?

by Dirk Hanson in Addiction Inbox


Teasing out the insulin effect.



On the face of it, the study seems to come out of left field: A group of researchers claimed that marijuana smokers showed 16 per cent lower fasting insulin levels than non-smokers. The study, called “The Impact of Marijuana Use on Glucose, Insulin, and Insulin Resistance among US Adults,”  is in press for The American Journal of Medicine. The authors are a diverse group of medical researchers from Harvard, Beth Israel Deaconess Medical Center, and t........ Read more »

  • May 22, 2013
  • 11:58 AM
  • 21 views

RNA was able to do some complex tasks in the start of Life on Ancient Earth

by Usman Paracha in SayPeople

Main Point:

Scientists have found that the complex biochemical changes through RNA may have been occurred in the start of the life on early Earth.

Published in:

Nature Chemistry

Study Further:

RNA (full form: ribonucleic acid) is a nucleic acid that has the sugar ribose, is found in all living cells, and is essential for the manufacture of proteins according to the instructions carried by genes. RNA also acts instead of DNA as the genetic material in certain viruses.

RNA is tho........ Read more »

Hsiao, C., Chou, I., Okafor, C., Bowman, J., O'Neill, E., Athavale, S., Petrov, A., Hud, N., Wartell, R., Harvey, S.... (2013) RNA with iron(II) as a cofactor catalyses electron transfer. Nature Chemistry, 5(6), 525-528. DOI: 10.1038/nchem.1649  

  • May 22, 2013
  • 09:32 AM
  • 26 views

Video Tip of the Week: Canary Database for sentinels of human health

by Mary in OpenHelix

Recently we attended the Medical Library Association conference (#MLAnet13). Librarians are working so hard to wrangle information into usable forms, and to generate new connections among data types to reveal new information and leads for further studies. I ♥ librarians. In one of the sessions I attended on Medical Informatics, I heard several great talks. One [...]... Read more »

  • May 22, 2013
  • 08:15 AM
  • 24 views

I Know Why She Swallowed The Fly

by Mark Lasbury in As Many Exceptions As Rules

It’s no secret that carnivorous plants are just way cool. Yet despite all the attention, there is still a lot we don’t know about them. Recent studies have expanded the view we have of these plants so that we now recognize more and more of them – like tomatoes and potatoes. Yes, our vegetables are insectivores!

New research has show that pitcher plants possess anti-microbial peptides in their pitchers, that some sundews can catapult insects into their traps in just a few mil........ Read more »

Poppinga, S., Hartmeyer, S., Seidel, R., Masselter, T., Hartmeyer, I., & Speck, T. (2012) Catapulting Tentacles in a Sticky Carnivorous Plant. PLoS ONE, 7(9). DOI: 10.1371/journal.pone.0045735  

Buch, F., Rott, M., Rottloff, S., Paetz, C., Hilke, I., Raessler, M., & Mithofer, A. (2012) Secreted pitfall-trap fluid of carnivorous Nepenthes plants is unsuitable for microbial growth. Annals of Botany, 111(3), 375-383. DOI: 10.1093/aob/mcs287  

Schulze, W., Sanggaard, K., Kreuzer, I., Knudsen, A., Bemm, F., Thogersen, I., Brautigam, A., Thomsen, L., Schliesky, S., Dyrlund, T.... (2012) The Protein Composition of the Digestive Fluid from the Venus Flytrap Sheds Light on Prey Digestion Mechanisms. Molecular , 11(11), 1306-1319. DOI: 10.1074/mcp.M112.021006  

  • May 22, 2013
  • 08:00 AM
  • 27 views

Down in the underground, scuds lose eyes but keep genes

by Zen Faulkes in NeuroDojo

When animals live caves full time, their descendents often lose their eyes. It has happened over and over and over and over again, in all different kinds of animals. But how this happens is not obvious. Stephen Jay Gould wrote that some people would use cave fish as an argument that “Lamarck must have been on to something” with his idea that acquired characteristics can be inherited. Well, no, that’s not that case, but it is a good example of how tricky thinking about losses can be.

The l........ Read more »

  • May 22, 2013
  • 07:07 AM
  • 25 views

Study Finds Why Penguins Lost Their Ability to Fly

by Katja Keuchenius in United Academics

If you’ve seen March of the Penguins, you probably understand the question. Many penguins live a shitty life, walking miles and miles without any food and spending months apart from their families. This would be over with if they just flew from one place to the other. So why did they stop doing that?... Read more »

  • May 22, 2013
  • 06:28 AM
  • 21 views

Double vision

by Perikis Livas in Tracing Knowledge

Scientists must ensure that they take the lead in the ethical debate surrounding the therapeutic use of stem cells derived from human clones.... Read more »

Nature Editorial. (2013) Double vision. Nature, 497(7450), 409-409. DOI: 10.1038/497409a  

  • May 22, 2013
  • 04:43 AM
  • 24 views

Bacterium excluded from the Eukaryote Club

by Roli Roberts in PLOS Biologue

It’s something you learn in high school – there are two basic approaches to cellular life – prokaryotes (bacteria and archaea) and eukaryotes (the rest of us – aardvarks, amoebae, apricots, etc.). Prokaryotes have an open-plan office, with all biological …... Read more »

  • May 21, 2013
  • 09:53 PM
  • 17 views

May 21, 2013

by Erin Campbell in HighMag Blog

“LET THERE BE LIGHT!” said the microscopist.  Light plays a crucial role in microscopy and cell biology, and a recent paper describes the use of light to understand protein secretion.Light is used in microscopy in countless ways—to illuminate a sample, excite a fluorophore, and signal the localization or dynamics of a protein.  Light can also be used to manipulate cellular events through the use of “caged” compounds that become active after illumination by certain wavelengths........ Read more »

Chen, D., Gibson, E., & Kennedy, M. (2013) A light-triggered protein secretion system. originally published in the Journal of Cell Biology, 201(4), 631-640. DOI: 10.1083/jcb.201210119  

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