Post List

Medicine posts

(Modify Search »)

  • November 30, 1999
  • 12:00 AM
  • 1,958 views

in indirect support of the hygiene hypothesis

by Ragamuffin in How We Are Hungry

A recent study out of the University of Michigan Medical School suggests that the stomach bacterium Helicobacter pylori protects against inflammation caused by Salmonella in a mouse model of Inflammatory Bowel Disease (IBD).... Read more »

  • November 30, 1999
  • 12:00 AM
  • 2,263 views

Mixture Models for Ordinal Data

by Christopher Winship in SMR Blog

Cumulative probability models are widely used for the analysis of ordinal data. In this article the authors propose cumulative probability mixture models that allow the assumptions of the cumulative probability model to hold within subsamples of the data. The subsamples are defined in terms of latent class membership. In the case of the ordered logit mixture model, on which the authors focus here, the assumption of a logistic distribution for an underlying latent dependent variable holds within ........ Read more »

Breen, R., & Luijkx, R. (2010) Mixture Models for Ordinal Data. Sociological Methods , 39(1), 3-24. DOI: 10.1177/0049124110366240  

  • November 30, 1999
  • 12:00 AM
  • 2,023 views

Let’s Get Cellular: Meth Metabolism

by Dirk Hanson in Addiction Inbox

We know from the work of Nora Volkow and others that meth abusers have chronically low levels of dopamine D2 receptors in their brains. But what is going on in the rest of the body when methamphetamine addiction is running full force?... Read more »

Sun, L., Li, H., Seufferheld, M., Walters, K., Margam, V., Jannasch, A., Diaz, N., Riley, C., Sun, W., Li, Y.... (2011) Systems-Scale Analysis Reveals Pathways Involved in Cellular Response to Methamphetamine. PLoS ONE, 6(4). DOI: 10.1371/journal.pone.0018215  

  • November 30, 1999
  • 12:00 AM
  • 2,207 views

Crystal structure solved by protein folding game players

by Olexandr Isayev in olexandrisayev.com

Following the failure of a wide range of attempts to solve the crystal structure of M-PMV retroviral protease by molecular replacement, authors challenged players of the protein folding game Foldit to produce accurate models of the protein. Remarkably, Foldit players were able to generate models of sufficient quality for successful molecular replacement and subsequent structure determination.... Read more »

Khatib, F., DiMaio, F., Cooper, S., Kazmierczyk, M., Gilski, M., Krzywda, S., Zabranska, H., Pichova, I., Thompson, J., Popović, Z.... (2011) Crystal structure of a monomeric retroviral protease solved by protein folding game players. Nature Structural . DOI: 10.1038/nsmb.2119  

  • November 30, 1999
  • 12:00 AM
  • 2,332 views

Comparing Apples with Oranges: B&W

by Peter Nollert in Protein Crystallization Blog

Identifying individual amino acid residues within a GPCR and comparing these across different receptors is a routine task that’s helped by a widely accepted nomenclature system: that of Ballesteros and Weinstein.... Read more »

  • November 30, 1999
  • 12:00 AM
  • 2,559 views

Cannabis law has no effect on cannabis use

by Neurobonkers in Neurobonkers

European Monitoring Centre for Drugs and Drug Addiction confirms that prohibition does not appear to effect levels of cannabis use in any way... Read more »

The european monitoring centre for drugs and drug addiction. (2011) The state of the drugs problem in Europe . Annual Report. info:/

  • November 30, 1999
  • 12:00 AM
  • 2,194 views

Synthesising Pseudoephedrine From N-Methylamphetamine

by Neurobonkers in Neurobonkers

The paper describes how “in the past most stores were able to sell pseudoephedrine”, the US’s most popular decongestant but new laws require pharmacies, often with restricted opening hours to sell the medicine only to those carrying government issued ID. The paper argues that “it would be of great interest to have a simple synthesis of pseudoephedrine from reagents which can be more readily procured”. The study is published in the splendidly titled Journal of Apocry........ Read more »

Hai, O. Hakkenshit, I.B. (2012) A Simple and Convenient Synthesis of Pseudoephedrine From N-Methylamphetamine. Journal of Apocryphal Chemistry, 213-21. info:/1F.1BC9/b00000F00A

  • November 30, 1999
  • 12:00 AM
  • 2,064 views

Brushing Your Teeth Keeps Your Heart Healthy

by United Academics in United Academics

Scientists at the Society for General Microbiology’s Spring Conference, which is taking place this week in Dublin, have explained how bacteria that linger in our mouth may cause endocarditis, an inflammation of the heart that can lead to dead.
... Read more »

  • November 30, 1999
  • 12:00 AM
  • 2,187 views

Blood Test to Predict Breast Cancer in Advance

by United Academics in United Academics

Five years from now it may be possible to prevent breast cancer by taking a simple blood test. New research shows that the chances of developing the disease are linked to a molecular modification of the gene ATM, present on white blood cells. In the future, doctors may identify women with this molecular modification to prevent breast cancer occurrence.... Read more »

Brennan, K., Garcia-Closas, M., Orr, N., Fletcher, O., Jones, M., Ashworth, A., Swerdlow, A., Thorne, H., , ., Riboli, E.... (2012) Intragenic ATM Methylation in Peripheral Blood DNA as a Biomarker of Breast Cancer Risk. Cancer Research, 72(9), 2304-2313. DOI: 10.1158/0008-5472.CAN-11-3157  

  • November 30, 1999
  • 12:00 AM
  • 1,802 views

“Beware of Exercise” is a Sexy Headline

by nooffensebut in The Unsilenced Science

A new study that raised concerns about exercise should instead raise concerns about obesity.... Read more »

Claude Bouchard, Steven Blair, Timothy Church, Conrad Earnest, James Hagberg, Keijo Häkkinen, Nathan Jenkins, Laura Karavirta, William Kraus, Arthur Leon.... (2012) Adverse Metabolic Response to Regular Exercise: Is It a Rare or Common Occurrence?. PLOS One, 7(5). info:/10.1371/journal.pone.0037887

  • November 30, 1999
  • 12:00 AM
  • 1,767 views

Vaccines: Myths and Realities

by Anton Power in BioMed Weekly

Summary of common myths and why they are wrong.... Read more »

De Wals P, Deceuninck G, Toth E, Boulianne N, Brunet D, Boucher RM, Landry M, & De Serres G. (2012) Risk of Guillain-Barré syndrome following H1N1 influenza vaccination in Quebec. JAMA : the Journal of the American Medical Association, 308(2), 175-81. PMID: 22782419  

  • November 30, 1999
  • 12:00 AM
  • 1,903 views

Fructose: friend or foe? Preliminary findings.

by Kismet in Biogerontology and Health

This discussion has been going on for quite some time and it is certainly not limited to the lay press and lay population. I have always been interested in double checking pop-sci claims, in this case the "evil fructose" meme.... Read more »

  • November 30, 1999
  • 12:00 AM
  • 1,796 views

Rats With (Not Quite) Telepathy

by Sedeer El-Showk in United Academics

Ten years ago, Professor Miguel Nicolelis and his team at Duke University made history. They implanted electrodes — sensors — into a monkey’s brain and trained her to control a robotic arm with her thoughts. That may sound like the stuff of science-fiction, but his latest work is even more incredible. In a paper recently published in Scientific Reports, Professor Nicolelis and his team used similar technology to enable a pair of rats to communicate — one brain to another ........ Read more »

  • November 30, 1999
  • 12:00 AM
  • 2,310 views

Understanding PREDIMED and the Mediterranean diet: heart-healthy or hype?

by Kismet in Biogerontology and Health

I am going to discuss the failings of the PREDIMED study, real and imagined. I will do this in a Question & Answer style. Several questions are inspired by theheart.org and NEJM comments and even statements by the low fat "gurus", Essselstyn, Ornish, McDougall or Pritikin. It is no surprise they are up in arms after the study has been published. It threatens their livelihood.... Read more »

Estruch, R., Ros, E., Salas-Salvadó, J., Covas, M., Corella, D., Arós, F., Gómez-Gracia, E., Ruiz-Gutiérrez, V., Fiol, M., Lapetra, J.... (2013) Primary Prevention of Cardiovascular Disease with a Mediterranean Diet. New England Journal of Medicine, 368(14), 1279-1290. DOI: 10.1056/NEJMoa1200303  

  • November 30, 1999
  • 12:00 AM
  • 1,717 views

Electron-spin clue to solving general anesthesia mystery

by This Science is Crazy! in This Science Is Crazy!

New study on fruit flies suggests general anesthetics can affect electron-spin properties... Read more »

Turin Luca, Skoulakis Efthimios, & Horsfield Andrew. (2014) Electron spin changes during general anesthesia in Drosophila. PNAS, Early edition(N/A). DOI: 10.1073/pnas.1404387111  

  • November 30, 1999
  • 12:00 AM
  • 1,540 views

Heroin’s Anthrax Problem

by Rebecca Kreston in BODY HORRORS

Anthrax is a deadly disease with high rates of morbidity and mortality. Because it is, thankfully, also quite rare, it is relatively easy to track its whereabouts and going-ons when an outbreak occurs. Typically, outbreaks of anthrax have been traced to groups of people involved in high-risk activities involving grazing animals and their byproducts: anthrax favors shepherds, butchers, wool-sorters, leather workers, and even the odd drum-playing hippies. In 2009, however, an outbreak upended this........ Read more »

  • November 30, 1999
  • 12:00 AM
  • 1,317 views

2014: The Year in Science

by Viputheshwar Sitaraman in Draw Science

The year in review: innovative discoveries and progress in all different fields of science. [Infographic]... Read more »

Qiu, X., Wong, G., Audet, J., Bello, A., Fernando, L., Alimonti, J., Fausther-Bovendo, H., Wei, H., Aviles, J., Hiatt, E.... (2014) Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp. Nature, 514(7520), 47-53. DOI: 10.1038/nature13777  

Obokata, H., Wakayama, T., Sasai, Y., Kojima, K., Vacanti, M., Niwa, H., Yamato, M., & Vacanti, C. (2014) Stimulus-triggered fate conversion of somatic cells into pluripotency. Nature, 505(7485), 641-647. DOI: 10.1038/nature12968  

Quintana, E., Barclay, T., Raymond, S., Rowe, J., Bolmont, E., Caldwell, D., Howell, S., Kane, S., Huber, D., Crepp, J.... (2014) An Earth-Sized Planet in the Habitable Zone of a Cool Star. Science, 344(6181), 277-280. DOI: 10.1126/science.1249403  

A.K. Geim, & K. S. Novoselov. (2010) The rise and rise of graphene. Nature Nanotechnology, 5(11), 755-755. DOI: 10.1038/nnano.2010.224  

  • November 30, 1999
  • 12:00 AM
  • 1,013 views

Recent reports on BHD and skin symptoms – misdiagnosis and new manifestations

by Joana Guedes in BHD Research Blog

Patients with Birt-Hogg-Dubé (BHD) syndrome usually develop benign hair follicle tumours (BHFTs) which appear as multiple whitish papules developing primarily on the face, neck and torso (Menko et al., 2009). BHFTs such as fibrofolliculomas and trichodiscomas (skin-coloured tumours occurring on the upper body) can be associated with various genetic conditions and their histology is often key to differential diagnosis. The morphology and histology of various BHFTs is discussed in a recent ........ Read more »

Del Rosso JQ, Silverberg N, & Zeichner JA. (2016) When Acne is Not Acne. Dermatologic clinics, 34(2), 225-8. PMID: 27015783  

  • November 30, 1999
  • 12:00 AM
  • 547 views

Highlights from the RLDC 2016 Cincinnati Conference

by Joana Guedes in BHD Research Blog

As mentioned in last week’s blog, the International Rare Lung Diseases Research Conference (RLDC) was held in Cincinnati, USA, 22nd-25th September. Clinicians, scientists, patient organizations, patients and families were brought together to discuss research and clinical trials in rare lung disease and to promote dialogue between the research community and patients.... Read more »

McCormack FX, Inoue Y, Moss J, Singer LG, Strange C, Nakata K, Barker AF, Chapman JT, Brantly ML, Stocks JM, Brown KK, Lynch JP 3rd, Goldberg HJ, Young LR, Kinder BW, Downey GP, Sullivan EJ, Colby TV, McKay RT, Cohen MM, Korbee L, Taveira-DaSilva AM, Lee . (2011) Efficacy and Safety of Sirolimus in Lymphangioleiomyomatosis. New England Journal of Medicine, 365(3), 271-272. DOI: 10.1056/NEJMc1106358  

  • November 30, 1999
  • 12:00 AM
  • 12 views

DHM attenuates obesity-induced slow-twitch-fiber decrease via FLCN/FNIP1/AMPK pathway

by Joana Guedes in BHD Research Blog

Obesity is often associated with decreases in the proportion of skeletal muscle slow-twitch fibers and insulin sensitivity. Slow-twitch fibers are rich in mitochondria and utilize fatty acid oxidative phosphorylation for energy production. In their new study, Zhou et al. (2017) explore the role of the FLCN/FNIP1/AMPK signalling pathway in obesity-induced reductions in slow-twitch fibers and insulin sensitivity in skeletal muscle using high-fat-diet-induced (HFD) obese mice, ob/ob mutant mice, an........ Read more »

join us!

Do you write about peer-reviewed research in your blog? Use ResearchBlogging.org to make it easy for your readers — and others from around the world — to find your serious posts about academic research.

If you don't have a blog, you can still use our site to learn about fascinating developments in cutting-edge research from around the world.

Register Now

Research Blogging is powered by SRI Technology.

To learn more, visit http://selfregulationinstitute.org/.