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  • November 14, 2011
  • 08:02 AM

How cancer-causing bacteria force your cells to die

by Lab Rat in Lab Rat Blog

The discovery that stomach ulcers are caused by bacteria is quite recent and was proved fairly conclusively in 1984 when the Australian scientist Barry Marshall drank a petri-dish full of the bacteria Helicobacter pylori and five days later developed serious gastritis, which cleared after antibiotic treatment. As stomach ulcers are quite common, and can be a major source of duodenal ulcers and stomach cancer, the discovery that they could be treated by a course of antibiotics was of major medic........ Read more »

  • November 14, 2011
  • 07:43 AM

The mChip can diagnose HIV in minutes - video

by United Academics in United Academics

A credit card-sized device called the mChip can diagnose HIV and syphilis in minutes in the remotest reaches of the developing world. The device was successfully field tested in Rwanda.... Read more »

Chin CD, Laksanasopin T, Cheung YK, Steinmiller D, Linder V, Parsa H, Wang J, Moore H, Rouse R, Umviligihozo G.... (2011) Microfluidics-based diagnostics of infectious diseases in the developing world. Nature medicine, 17(8), 1015-9. PMID: 21804541  

  • November 14, 2011
  • 07:02 AM

K2 Synthetic Marijuana: Heart Attacks, Suicides, and Surveillance

by David J Kroll in Terra Sigillata

Sixteen-year-old boys having heart attacks. Blog reports of deaths and suicides. And a little known chemistry and public health resource mobilized to identify “legal highs.” The chemical and biological phenomenon that is “synthetic marijuana” continued to develop over the last week as we learn more about these products from the medical and public health communities. [...]... Read more »

  • November 14, 2011
  • 05:20 AM

Can you spot the fake brain computer interface?

by Neurobonkers in Neurobonkers

A team of bogus developers are applying for crowd funding for a project that does not exist. Can you spot the flaws?... Read more »

Damian Cruse, Srivas Chennu, Camille Chatelle, Tristan A Bekinschtein, Davinia Fernández-Espejo, John D Pickard, Steven Laureys, Adrian M Owen. (2011) Bedside detection of awareness in the vegetative state: a cohort study. The Lancet. info:/10.1016/S0140-6736(11)61224-5

  • November 14, 2011
  • 12:01 AM

Diagnosis of Exercise-Induced Bronchoconstriction: Eucapnic Voluntary Hyperpnoea Challenges

by Hallie Labrador, Marc Harwood in Sports Medicine Research (SMR): In the Lab & In the Field

xercise-induced bronchospasm (EIB) is an obstruction of transient airflow that usually occurs 5-15 minutes after exercise. Although the previously reported incidence of EIB has been around 20%, the authors of this manuscript believe that (EIB) may be more prevalent than clinicians think and should be screened for. The purpose of this study was to use a eucapnic voluntary hyperventilation (EVH) challenge as a surrogate for exercise to screen elite British athletes for EIB.... Read more »

  • November 13, 2011
  • 10:00 AM

Does bestiality increase your risk of penile cancer?

by Tara Smith in Aetiology

Aah, the things one learns when awake at 3AM on a Saturday night. Via a few different Tweeps, I ran across this article from Men's Health magazine, titled "Urgent Warning: Sex with Animals Causes Cancer."

I probably should have just stopped there.

But no, I read the magazine article, which states:

Brazilian researchers polled nearly 500 men from a dozen cities, and found that--we're not joking around here--roughly 35 percent of the men had "made it" with an animal. That's a problem, because ........ Read more »

Zequi SD, Guimarães GC, da Fonseca FP, Ferreira U, de Matheus WE, Reis LO, Aita GA, Glina S, Fanni VS, Perez MD.... (2011) Sex with Animals (SWA): Behavioral Characteristics and Possible Association with Penile Cancer. A Multicenter Study. The journal of sexual medicine. PMID: 22023719  

  • November 13, 2011
  • 06:14 AM

Vitamins, genes and language

by Dorothy Bishop in bishopblog

An accidental omission led to thiamine deficiency in a formula-fed group of babies. A follow-up study has found that this group has specific language impairment at 5-7 years of age. ... Read more »

Villanueva P, Newbury DF, Jara L, De Barbieri Z, Mirza G, Palomino HM, Fernández MA, Cazier JB, Monaco AP, & Palomino H. (2011) Genome-wide analysis of genetic susceptibility to language impairment in an isolated Chilean population. European journal of human genetics : EJHG, 19(6), 687-95. PMID: 21248734  

  • November 12, 2011
  • 07:27 AM

Autism: What A Big Prefrontal Cortex You Have

by Neuroskeptic in Neuroskeptic

A new paper has caused a lot of excitement: it reports large increases in the number of neurons in children with autism. It comes to you from veteran autism researcher Eric Courchesne. Courchesne et al counted the number of cells in the prefrontal cortex of 7 boys with autism and 6 non-autistic control boys, aged 2-16 years old. The analysis was performed by a neuropathologist who was blind to the theory behind the study and to which brains were from which group. That's good.They found that the ........ Read more »

Courchesne E, Mouton PR, Calhoun ME, Semendeferi K, Ahrens-Barbeau C, Hallet MJ, Barnes CC, & Pierce K. (2011) Neuron number and size in prefrontal cortex of children with autism. JAMA : the journal of the American Medical Association, 306(18), 2001-10. PMID: 22068992  

  • November 11, 2011
  • 12:36 PM

Testosterone Boosts Sexual Function in Men on SSRIs

by William Yates, M.D. in Brain Posts

Selective serotonin reuptake inhibitor antidepressants (SSRIs) such as fluoxetine (Prozac) continue to be a common first-line treatment for major depression and a variety of anxiety disorders.  Although generally well tolerated, sexual side effects are common in both men and women taking SSRIs.There are a variety of options for managing sexual side effects.  These can include reducing the dose of the SSRI, switching (or augmenting) with antidepressants without sexual side effects or in........ Read more »

  • November 11, 2011
  • 11:59 AM

Epigenetics – an emerging new potential treatment for lung cancer?

by Sally Church in Pharma Strategy Blog

This study demonstrated that combined epigenetic therapy with low-dose azacitidine and entinostat resulted in objective, durable responses in patients with lung cancer and defined a blood-based biomarker that correlated with clinical benefit.... Read more »

Bird, A. (2007) Perceptions of epigenetics. Nature, 447(7143), 396-398. DOI: 10.1038/nature05913  

Brock, M., Hooker, C., Ota-Machida, E., Han, Y., Guo, M., Ames, S., Glöckner, S., Piantadosi, S., Gabrielson, E., Pridham, G.... (2008) DNA Methylation Markers and Early Recurrence in Stage I Lung Cancer. New England Journal of Medicine, 358(11), 1118-1128. DOI: 10.1056/NEJMoa0706550  

Juergens, R., Wrangle, J., Vendetti, F., Murphy, S., Zhao, M., Coleman, B., Sebree, R., Rodgers, K., Hooker, C., Franco, N.... (2011) Combination Epigenetic Therapy Has Efficacy in Patients with Refractory Advanced Non-Small Cell Lung Cancer. Cancer Discovery. DOI: 10.1158/2159-8290.CD-11-0214  

  • November 11, 2011
  • 10:00 AM

Blog Roundtable: Are there tips for fighting impostor syndrome?

by Mr Epidemiology in Mr Epidemiology

This blog roundtable is part of a series about graduate school – why do it, what is it like, and what to do afterwards. I encourage you to give your own opinions in the comments section, and if you disagree with a point made by the panel, voice your opinion! This is something a lot [...]... Read more »

  • November 11, 2011
  • 06:53 AM

Sex with animals causes penile cancer

by United Academics in United Academics

Although most countries already prohibit sex with animals, a new study finds yet another reason to avoid bestiality. This study, published in the Journal of Sexual Medicine, suggests there’s a link between bestiality and penile cancer.... Read more »

Zequi SD, Guimarães GC, da Fonseca FP, Ferreira U, de Matheus WE, Reis LO, Aita GA, Glina S, Fanni VS, Perez MD.... (2011) Sex with Animals (SWA): Behavioral Characteristics and Possible Association with Penile Cancer. A Multicenter Study. The journal of sexual medicine. PMID: 22023719  

  • November 11, 2011
  • 02:27 AM

Another Antidepressant Bites The Dust

by Neuroskeptic in Neuroskeptic

Yet another up-and-coming antidepressant has flopped.A paper just out reveals that the snappily-named GSK372475 doesn't work and has lots of side effects. It's a report of two clinicals trials in which Glaxo's contender was pitched against placebo and against older antidepressants in the treatment of depression.GSK372475 failed to improve depression any better than placebo, even though the trials were large (393 and 504 patients respectively) and twice as long as most antidepressant trials (10 w........ Read more »

  • November 11, 2011
  • 02:06 AM

Themes of medical education research

by Dr Shock in Dr Shock MD PhD

Buffer From a content analysis on 10.168 abstracts extracted from the six most influential journals in medical education published since 1988, 29 major themes were identified for research in this field. In short most of the themes were about the preparation of medical students for professional practice. From the analysis the following topics were the [...]

No related posts.... Read more »

  • November 11, 2011
  • 12:01 AM

Asymptomatic Achilles, Patellar, and Quadriceps Tendinopathy on Diagnostic Ultrasound

by Stephen Thomas in Sports Medicine Research (SMR): In the Lab & In the Field

Tendinopathy is common among athletes of all shapes and sizes. Chronically tendinopathy is much more common than acute tendinopathy and is typically caused by overuse stress which causes collagen degeneration. Elite fencers perform repetitive motions during competition and therefore are prone to overuse conditions in the tendons of the lower extremity. With the advances in medical technology ultrasound has drastically improved and become more common in the sports medicine setting for diagnosing ........ Read more »

  • November 10, 2011
  • 08:30 PM

Update on pancreatic neuroendocrine tumors (NET)

by Sally Church in Pharma Strategy Blog

The idea though, of an Awareness Day for a rare disease such as NET to improve both education and awareness seems an inherently good one to me, especially as there has been some progress clinically in 2011. According to Kulke et al., (2011) NET has an incidence of around 1 per 100,000 individuals. This excellent journal review covers the key essentials of both the disease and the treatments.... Read more »

  • November 10, 2011
  • 08:15 PM

Know your fat!

by NerdyOne in Try Nerdy

A lot of people might think that their fat is just sitting there, keeping them fat. And I’m not saying they’re wrong, but fat (also known as adipose tissue) is far from a one-trick pony. So with the barrage of products out there telling us to “burn,” “shrink,” and “eliminate” fat, isn’t is only fair that we take stock of what fat’s doing in our bodies in the first place?

You may not exactly like the things you learn about fat in toda........ Read more »

  • November 10, 2011
  • 02:36 PM

Let’s Learn From Ourselves How We Can Improve Pain Management

by Kim Kristiansen in Picture of Pain

Chronic pain is more frequent than diabetes, cancer and coronary heart disease combined [1]. American Pain Foundation has calculated this, I have calculated same proportion for Denmark, and I am sure similar proportions can be found for every country in the western world. It is of cause an eye opener for how we use our resources, priority, awareness and educational activities in health care, but it can actually also be used for something else and indeed important.... Read more »

Kim Kristiansen, M.D. (2011) Let’s Learn From Ourselves How We Can Improve Pain Management . Picture of Pain Blog. info:/’s-learn-from-ourselves-how-we-can-improve-pain-management/

  • November 10, 2011
  • 01:41 PM

Fantastic free new academic search tool for tracking down -ve findings

by Neurobonkers in Neurobonkers

Does what it says on the tin.... Read more »

  • November 10, 2011
  • 10:32 AM

Update on pancreatic Neuroendocrine Tumours (NET)

by Sally Church in Pharma Strategy Blog

Today on 10th November, it’s the Second Annual Worldwide NET (Neuroendocrine Tumor) Cancer Awareness Day. Granted that’s a bit of a mouthful, but it also seems poignant given so many of my news feeds this morning were still full of … Continue reading →
... Read more »

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