A discussion of a peer reviewed publication in PLoS Medicine regarding the use of Prophylactic Adrenaline for prevention of Anti snake venom indiced anaphylaxis.... Read more »
de Silva, H., Pathmeswaran, A., Ranasinha, C., Jayamanne, S., Samarakoon, S., Hittharage, A., Kalupahana, R., Ratnatilaka, G., Uluwatthage, W., Aronson, J.... (2011) Low-Dose Adrenaline, Promethazine, and Hydrocortisone in the Prevention of Acute Adverse Reactions to Antivenom following Snakebite: A Randomised, Double-Blind, Placebo-Controlled Trial. PLoS Medicine, 8(5). DOI: 10.1371/journal.pmed.1000435
It seems that cat-like reflexes pay off for solar cell technology... Nanowhiskers deposited on traditional silicon solar cells help in the harvesting of bountiful deep-red solar rays. Researchers are steadily making progress towards improved solar cell technologies, like Combine harvesters barreling down a field of tall golden crop. The benefits are huge; the problem is getting there without spending a fortune. A major limitation in the harvesting of solar energy is a common problem in almost ev........ Read more »
Chang CH, Yu P, Hsu MH, Tseng PC, Chang WL, Sun WC, Hsu WC, Hsu SH, & Chang YC. (2011) Combined micro- and nano-scale surface textures for enhanced near-infrared light harvesting in silicon photovoltaics. Nanotechnology, 22(9), 95201. PMID: 21258142
Yesterday I happened to see a tweet from the Ohio State University Medical Center's twitter account that linked to a press release discussing a new plasminogen activator that is currently undergoing clinical trials. The drug, desmoteplase, is modeled after a protein found in vampire bat saliva that prevents clots and platelet aggregation, which keeps the blood flowing while the bat is feeding. Plasminogen activators like desmoteplase are used to break down blood clots that are blocking bloo........ Read more »
HAWKEY, C. (1966) Plasminogen Activator in Saliva of the Vampire Bat Desmodus rotundus. Nature, 211(5047), 434-435. DOI: 10.1038/211434c0
Hawkey, C. (1967) Inhibitor of Platelet Aggregation Present in Saliva of the Vampire Bat Desmodus rotundus. British Journal of Haematology, 13(6), 1014-1020. DOI: 10.1111/j.1365-2141.1967.tb08870.x
Schleuning, W. (2001) Vampire Bat Plasminogen Activator DSPA-Alpha-1 (Desmoteplase): A Thrombolytic Drug Optimized by Natural Selection. Pathophysiology of Haemostasis and Thrombosis, 31(3-6), 118-122. DOI: 10.1159/000048054
A report published last week by the Danish company KMD contains a survey among 1100 Danish patients with chronic diseases It seems that we can provide better care for lower costs using telemedicine. www.dolotest.com... Read more »
Kim Kristiansen, M.D. (2011) Patients with Chronic Conditions Want Telemedicine Study Shows. Picture of Pain Blog. info:/hhttp://blog.dolotest.com/?p
How a man survived for 90 minutes without a pulse.... Read more »
White RD, Goodman BW, & Svoboda MA. (2011) Neurologic Recovery Following Prolonged Out-of-Hospital Cardiac Arrest With Resuscitation Guided by Continuous Capnography. Mayo Clinic proceedings. Mayo Clinic. PMID: 21508320
Today is the Mental Health Blog Party sponsored by the American Psychological Association as part of Mental Health Month. A widely neglected part of mental health treatment is encouraging and maintaining good physical health. This is extremely difficult when some of the major drugs prescribed for serious mental illnesses (such as schizophrenia and bipolar disorder) produce substantial weight gain. The "second generation" or atypical antipsychotics can cause obesity and hence diabetes, hypertensi........ Read more »
Chang, C., Hayes, R., Perera, G., Broadbent, M., Fernandes, A., Lee, W., Hotopf, M., & Stewart, R. (2011) Life Expectancy at Birth for People with Serious Mental Illness and Other Major Disorders from a Secondary Mental Health Care Case Register in London. PLoS ONE, 6(5). DOI: 10.1371/journal.pone.0019590
Daumit, G., Dalcin, A., Jerome, G., Young, D., Charleston, J., Crum, R., Anthony, C., Hayes, J., McCarron, P., Khaykin, E.... (2010) A behavioral weight-loss intervention for persons with serious mental illness in psychiatric rehabilitation centers. International Journal of Obesity. DOI: 10.1038/ijo.2010.224
May is "Mental Health Month" and today is "Mental Health Month Blog Party," an initiative of the American Psychological Association's Public Education Campaign. Today, bloggers who write about mental health issues will be linked to on APA's public information web site:http://www.yourmindyourbody.org/So, since every bariatric surgery patient is indoctrinated with the message, "Bariatric surgery is a tool, not a panacea, and I know I have to make lifestyle changes to maintain my weight loss," I th........ Read more »
Eisenberg, D., Duffy, A., & Bell, R. (2010) Does Preoperative Weight Change Predict Postoperative Weight Loss after Laparoscopic Roux-en-Y Gastric Bypass in the Short Term?. Journal of Obesity, 1-4. DOI: 10.1155/2010/907097
Ebola has long been associated with wildlife. From the early days, bats were viewed as a potential reservoir (though it wasn't confirmed that they actually harbored the virus until 2005). Contact with wild animals--particularly primates which were butchered for food--was also long thought to be a risk factor, and now we know that primates can become ill with Ebola and pass the virus to humans.
What hadn't been examined until 2008 were pigs. I mean, it's not exactly the animal you associate wit........ Read more »
Kobinger GP, Leung A, Neufeld J, Richardson JS, Falzarano D, Smith G, Tierney K, Patel A, & Weingartl HM. (2011) Replication, Pathogenicity, Shedding, and Transmission of Zaire ebolavirus in Pigs. The Journal of infectious diseases. PMID: 21571728
Not that long ago Mary posted on updates that occurred recently at the Allen Institute for Brain Science & hinted that there might be a tip coming about their cool 3D Brain Explorer tool – well, today’s the day! As Mary mentions in her post, the Allen Institute has created some phenomenal tools and detailed datasets for brain
From the Brain Explorer documentation, the Explorer allows users to:
# View a fully interactive version of the Allen Human Brain Atlas in 3D for two donors.
........ Read more »
Lau, C., Ng, L., Thompson, C., Pathak, S., Kuan, L., Jones, A., & Hawrylycz, M. (2008) Exploration and visualization of gene expression with neuroanatomy in the adult mouse brain. BMC Bioinformatics, 9(1), 153. DOI: 10.1186/1471-2105-9-153
The good news is that a tendency to binge on diet-destroyers is likely to be a matter of genes. The bad news is that our brain, body and external environment can fire up this tendency making some of us more likely to binge eat than others. Dietary restraint or just plain dieting involves a conscious [...]... Read more »
Racine SE, Burt SA, Iacono WG, McGue M, & Klump KL. (2011) Dietary restraint moderates genetic risk for binge eating. Journal of abnormal psychology, 120(1), 119-28. PMID: 21171725
One of the stranger Internet-based quackery phenomenons of the last decade is Morgellon's disease. This is a topic I haven't visited that much on this blog, its having last come up in a big way a little more than a year ago, when I discussed it in the context of Dr. Rolando Arafiles and the other quackery he was promoting. This led to extreme unhappiness on the part of self-proclaimed Morgellons disease "expert" Marc Neumann, who later bombarded me with threatening e-mail rants. In any case, wha........ Read more »
Hylwa, S., Bury, J., Davis, M., Pittelkow, M., & Bostwick, J. (2011) Delusional Infestation, Including Delusions of Parasitosis: Results of Histologic Examination of Skin Biopsy and Patient-Provided Skin Specimens. Archives of Dermatology. DOI: 10.1001/archdermatol.2011.114
An examination of a recent paper on maternal breast size after pregnancy, and the Trivers-Willard hypothesis.... Read more »
Dimitrakakis C, Jones RA, Liu A, & Bondy CA. (2004) Breast cancer incidence in postmenopausal women using testosterone in addition to usual hormone therapy. Menopause (New York, N.Y.), 11(5), 531-5. PMID: 15356405
Galbarczyk A. (2011) Unexpected changes in maternal breast size during pregnancy in relation to infant sex: An evolutionary interpretation. American journal of human biology : the official journal of the Human Biology Council. PMID: 21544894
Helle, S. (2002) Sons Reduced Maternal Longevity in Preindustrial Humans. Science, 296(5570), 1085-1085. DOI: 10.1126/science.1070106
Hinde K. (2009) Richer milk for sons but more milk for daughters: Sex-biased investment during lactation varies with maternal life history in rhesus macaques. American journal of human biology : the official journal of the Human Biology Council, 21(4), 512-9. PMID: 19384860
Hrdy, S. (1990) Sex bias in nature and in history: A late 1980s reexamination of the “biological origins” argument. American Journal of Physical Anthropology, 33(S11), 25-37. DOI: 10.1002/ajpa.1330330504
Jasienska G, Nenko I, & Jasienski M. (2006) Daughters increase longevity of fathers, but daughters and sons equally reduce longevity of mothers. American journal of human biology : the official journal of the Human Biology Council, 18(3), 422-5. PMID: 16634019
Poretsky L, Seto-Young D, Shrestha A, Dhillon S, Mirjany M, Liu HC, Yih MC, & Rosenwaks Z. (2001) Phosphatidyl-inositol-3 kinase-independent insulin action pathway(s) in the human ovary. The Journal of clinical endocrinology and metabolism, 86(7), 3115-9. PMID: 11443175
A case report from India describes a man who became suicidally depressed while being given drugs to treat a viral infection:A 43-year-old man diagnosed with chronic hepatitis C viral infection ... was started on therapy with interferon -α-2a and ribavirin ... Screening tests for hepatitis B virus, hepatitis A virus, and HIV were negative.In initial 3 months of start of therapy with IFN-α-2a and ribavirin, the patient experienced adverse effects in the form of high-grade fever, malaise, mya........ Read more »
Inder D, Rehan HS, Yadav M, Manak S, & Kumar P. (2011) IFN-α-2a (Interferon) and ribavirin induced suicidal attempt in a patient of chronic HCV: A rare case report. Indian journal of pharmacology, 43(2), 210-1. PMID: 21572662
A little over ten years ago, I lost my Father to metastatic prostate cancer, a brave fight that lasted only a few years since he was diagnosed with stage IV disease. In many ways though, it was a bittersweet … Continue reading →
... Read more »
Sartor, O. (2011) Denosumab in bone-metastatic prostate cancer: known effects on skeletal-related events but unknown effects on quality of life. Asian Journal of Andrology. DOI: 10.1038/aja.2011.33
Scientists have tested the old Danish myth that it is possible to get drunk by submerging your feet in alcohol. Their results, indicate that unfortunately a Fosters footbath is unlikely to become the new way to consume your drinks. The selfless scientists from the Department of Cardiology at Hillerød Hospital became the test subjects (Figure 1), declaring … Read more... Read more »
Hansen CS, Faerch LH, & Kristensen PL. (2010) Testing the validity of the Danish urban myth that alcohol can be absorbed through feet: open labelled self experimental study. BMJ (Clinical research ed.). PMID: 21156749
We have discussed the term empathy several times.
The most clarifying definition of empathy is based on viewing it as a process. This process of empathy consists of the following stages.
The patient expresses feelings by way of verbal and non-verbal communication. Patients are not always aware of these expressions.
The doctor also notices these emotions in himself [...]
No related posts.... Read more »
Smajdor, A., Stockl, A., & Salter, C. (2011) The limits of empathy: problems in medical education and practice. Journal of Medical Ethics. DOI: 10.1136/jme.2010.039628
News that gay men get more cancer than straight men (Boehmer et al. 2011) is not new, even when not taking into consideration the insidious impact of HIV. Why, as in this study, gay men are twice as likely as straight men to get cancer is not successfully resolved, other than to stress the critical role played by anal sex and I would add, HPV. ... Read more »
The anti-vaccine movement is a frequent topic on this blog, sometimes to the point where it seems to take over the blog for days (or even weeks) at a time and I cry for respite. There are a number of reasons for this, not the least of which being that the anti-vaccine movement is one of the most dangerous forms of pseudoscience, a form of quackery that, unlike most forms of quackery, endangers those who do not partake of it by breaking down herd immunity and paving the way for the resurgence of ........ Read more »
Miller, N., & Goldman, G. (2011) Infant mortality rates regressed against number of vaccine doses routinely given: Is there a biochemical or synergistic toxicity?. Human . DOI: 10.1177/0960327111407644
A review of Isabel’s World by Roy Richard Grinker
Author is parent of child with autism and also cultural anthropologist. Looks at reasons for 'autism epidemic' and contrasts autism diagnosis in different countries... Read more »
Bishop, D., Whitehouse, A., Watt, H., & Line, E. (2008) Autism and diagnostic substitution: evidence from a study of adults with a history of developmental language disorder. Developmental Medicine , 50(5), 341-345. DOI: 10.1111/j.1469-8749.2008.02057.x
by David Gorski in Science-Based Medicine
Dr. Andrew Weil is a rock star in the “complementary and alternative medicine” (CAM) and “integrative medicine” (IM) movement. Indeed, it can be persuasively argued that he is one of its founders, at least a founder of the its most modern iteration, and I am hard-pressed to think of anyone who did more in the [...]... Read more »
Shannon, S., Weil, A., & Kaplan, B. (2011) Medical Decision Making in Integrative Medicine: Safety, Efficacy, and Patient Preference. Alternative and Complementary Therapies, 17(2), 84-91. DOI: 10.1089/act.2011.17210
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