Post List

Medicine posts

(Modify Search »)

  • September 15, 2014
  • 04:47 AM
  • 514 views

Zinc and copper and autism

by Paul Whiteley in Questioning Answers

The paper by Li and colleagues [1] looking at serum copper (Cu) and zinc (Zn) levels in a group of participants diagnosed with an autism spectrum disorder (ASD) is the source material for today's post. Highlighting how "mean serum Zn levels and Zn/Cu ratio were significantly lower in children with ASD compared with normal cases... whereas serum Cu levels were significantly higher" the continued focus on the metallome in autism carries on at a pace. I should at this point out that I'm not in........ Read more »

  • September 15, 2014
  • 12:05 AM
  • 664 views

Acute Gains in Motion After Single Bout of Stretching Predicts Short-Term Gains

by Jane McDevitt in Sports Medicine Research (SMR): In the Lab & In the Field

Acute changes in flexibility after either static or PNF stretching predict the gains in flexibility after a 7-day stretching program.... Read more »

  • September 14, 2014
  • 02:24 PM
  • 634 views

Biospleen Helps Clean Blood to Prevent Sepsis

by Dr. Jekyll in Lunatic Laboratories

When a patient has sepsis Things can go downhill fast. A life-threatening condition in which bacteria or fungi multiply in a patient's blood -- sepsis is often too fast for antibiotics to help. But that's all about to change with the introduction of a new device -- inspired by the human spleen -- that may radically transform the way doctors treat sepsis.... Read more »

Kang JH, Super M, Yung CW, Cooper RM, Domansky K, Graveline AR, Mammoto T, Berthet JB, Tobin H, Cartwright MJ.... (2014) An extracorporeal blood-cleansing device for sepsis therapy. Nature medicine. PMID: 25216635  

  • September 14, 2014
  • 01:00 AM
  • 1,130 views

Telepathy is Almost Here

by Viputheshwar Sitaraman in Draw Science

Telepathy is under works; it's just super clunky right now. Non-invasive technology enables brain-to-brain communication by converting words into binary and from binary into pulses of light and back. [Infographic]... Read more »

Grau C, Ginhoux R, Riera A, Nguyen TL, Chauvat H, Berg M, Amengual JL, Pascual-Leone A, & Ruffini G. (2014) Conscious Brain-to-Brain Communication in Humans Using Non-Invasive Technologies. PloS one, 9(8). PMID: 25137064  

  • September 13, 2014
  • 01:13 PM
  • 762 views

Need a Kidney? Lab Grown Kidneys Coming Soon!

by Dr. Jekyll in Lunatic Laboratories

Stem cells offered the promise of having a patents own organ grown to replace a failing or damaged one. Unfortunately the road to that future has been paved with seemingly insurmountable challenges. Thankfully now we are one step closer, researchers have addressed a major challenge in the quest to build replacement kidneys in the lab. Working with human-sized pig kidneys, the scientists developed the most successful method to date to keep blood vessels in the new organs open and flowing with blo........ Read more »

In Kap Ko,, Mehran Abolbashari,, Jennifer Huling,, Cheil Kim,, Sayed-Hadi Mirmalek-Sani,, Mahmoudreza Moradi,, Giuseppe Orlando,, John D. Jackson,, Tamer Aboushwareb,, Shay Soker,.... (2014) Enhanced re-endothelialization of acellular kidney scaffolds for whole organ engineering via antibody conjugation of vasculatures. Technology . info:/10.1142/S2339547814500228

  • September 12, 2014
  • 09:52 PM
  • 865 views

The Re-emergence of the Minimal Running Shoe

by Craig Payne in Running Research Junkie

The Re-emergence of the Minimal Running Shoe ... Read more »

Davis IS. (2014) The Re-emergence of the Minimal Running Shoe. The Journal of orthopaedic and sports physical therapy, 1-19. PMID: 25211531  

  • September 12, 2014
  • 03:44 PM
  • 500 views

Inflammation of the Brain and Memory Problems

by Dr. Jekyll in Lunatic Laboratories

Neurological disorders typically involve memory issues. Most of the problems are attributed to plaques that build up in the brain (which are typically prions), yet some causes are unknown. New research however sheds some light on at least one cause of memory problems. As it turns out brain inflammation can rapidly disrupt our ability to retrieve complex memories of similar but distinct experiences.... Read more »

  • September 12, 2014
  • 11:47 AM
  • 492 views

Insulin, growth hormone and risk of schizophrenia?

by Paul Whiteley in Questioning Answers

"Overall, the present findings suggest that metabolic and hormonal disturbances such as effects on insulin and growth hormone may represent a vulnerability factor to develop mental disorders". That was the conclusion reported by van Beveren and colleagues [1] (open-access) looking at "disruption of insulin and growth factor signaling pathways as an increased risk factor for schizophrenia"."Years ago you served my father in the Clone Wars"Drawing on data derived from participants taking part in&n........ Read more »

  • September 12, 2014
  • 09:15 AM
  • 559 views

The Friday Five for 09/12/2014

by Bill Sullivan in The 'Scope

Get caught up quick on the hottest science news from this week!... Read more »

Denoeud, F., Carretero-Paulet, L., Dereeper, A., Droc, G., Guyot, R., Pietrella, M., Zheng, C., Alberti, A., Anthony, F., Aprea, G.... (2014) The coffee genome provides insight into the convergent evolution of caffeine biosynthesis. Science, 345(6201), 1181-1184. DOI: 10.1126/science.1255274  

  • September 11, 2014
  • 08:21 PM
  • 647 views

"Barefoot Running and Hip Kinematics: Good News for the Knee?"; what about "Bad News for the Ankle"?

by Craig Payne in Running Research Junkie

"Barefoot Running and Hip Kinematics: Good News for the Knee?"; what about "Bad News for the Ankle"?... Read more »

McCarthy C, Fleming N, Donne B, & Blanksby B. (2014) Barefoot Running and Hip Kinematics: Good News for the Knee?. Medicine and science in sports and exercise. PMID: 25207927  

  • September 11, 2014
  • 12:45 PM
  • 567 views

The Origami Brain and a new marker for Schizophrenia

by Dr. Jekyll in Lunatic Laboratories

Anyone who has seen pictures or models of the human brain (like the one above) is aware that the outside layer, or cortex, of the brain is folded in an intricate pattern of “hills”, called gyri, and “valleys”, called sulci which give the brain it’s distinctive look. It turns out that the patterns of cortical folding are largely consistent across healthy humans, broadly speaking. However, disturbances in cortical folding patterns suggest deeper disturbances in brain structure and functi........ Read more »

Nanda P, Tandon N, Mathew IT, Giakoumatos CI, Abhishekh HA, Clementz BA, Pearlson GD, Sweeney J, Tamminga CA, & Keshavan MS. (2014) Local gyrification index in probands with psychotic disorders and their first-degree relatives. Biological psychiatry, 76(6), 447-55. PMID: 24369266  

  • September 11, 2014
  • 09:55 AM
  • 552 views

Treating autism in the first year of life

by Paul Whiteley in Questioning Answers

I had been waiting y'know. Waiting a while for the paper by Sally Rogers and colleagues [1] to finally appear quite a few days after the media headlines about 'reducing', 'reversing' and even 'eliminating' the signs and symptoms of autism in early infancy had appeared. Personally, I prefer the New Scientist headline: 'Early autism intervention speeds infant development' given the text of the paper. I should perhaps also add the words 'for some' to that sentence as you will hopefully see...I........ Read more »

S. J. Rogers, L. Vismara, A. L. Wagner, C. McCormick, G. Young, & S. Ozonoff. (2014) Autism Treatment in the First Year of Life: A Pilot Study of Infant Start, a Parent-Implemented Intervention for Symptomatic Infants. Journal of Autism and Developmental Disorders. info:/10.1007/s10803-014-2202-y

  • September 11, 2014
  • 04:42 AM
  • 495 views

Omega-3 fatty acids rescues Fragile X phenotypes in Fmr1-Ko mice

by Paul Whiteley in Questioning Answers

"These results demonstrate that n-3 PUFAs dietary supplementation, although not a panacea, has a considerable therapeutic value for FXS [Fragile X syndrome] and potentially for ASD [autism spectrum disorder], suggesting a major mediating role of neuroinflammatory mechanisms".A view @ Wikipedia That was the conclusion reached by Susanna Pietropaolo and colleagues [1] who "evaluated the impact of n-3 PUFA dietary supplementation in a mouse model of fragile X syndrome ........ Read more »

Pietropaolo S, Goubran MG, Joffre C, Aubert A, Lemaire-Mayo V, Crusio WE, & Layé S. (2014) Dietary supplementation of omega-3 fatty acids rescues fragile X phenotypes in Fmr1-Ko mice. Psychoneuroendocrinology, 119-129. PMID: 25080404  

  • September 10, 2014
  • 08:26 PM
  • 669 views

Patellofemoral Joint Stress during Running with Alterations in Foot Strike Pattern

by Craig Payne in Running Research Junkie

Patellofemoral Joint Stress during Running with Alterations in Foot Strike Pattern... Read more »

  • September 10, 2014
  • 06:00 PM
  • 110,630 views

Anecdotes and the Appearance of Improvement

by Rogue Medic in Rogue Medic

We like to give treatments that produce results that we can see and logically attribute to the treatments we gave.

We like to give IV (IntaVenous) furosemide (Lasix – frusemide in Commonwealth countries) for CHF (Congestive Heart Failure).

1. The patient had CHF.
2. I gave IV furosemide.
3. The patient produced urine.... Read more »

  • September 10, 2014
  • 02:26 PM
  • 680 views

Multiple Sclerosis and Myelin loss

by Dr. Jekyll in Lunatic Laboratories

Multiple sclerosis (MS) is an unpredictable, often disabling disease of the central nervous system that disrupts the flow of information within the brain, and between the brain and body. The exact cause is unknown, however people with multiple sclerosis lose myelin in the gray matter of their brains and the loss is closely correlated with the severity of the disease, according to a new magnetic resonance imaging (MRI) study.... Read more »

Vasily L. Yarnykh, James D. Bowen, Alexey Samsonov, Pavle Repovic, Angeli Mayadev, Peiqing Qian, Beena Gangadharan, Bart P. Keogh, Kenneth R. Maravilla, & Lily K. Jung Henson. (2014) Fast Whole-Brain Three-dimensional Macromolecular Proton Fraction Mapping in Multiple Sclerosis. Radiological Society of North America . info:/10.1148/radiol.14140528

  • September 10, 2014
  • 09:36 AM
  • 538 views

Video Tip of the Week: #Docker, shipping containers for software and data

by Mary in OpenHelix

Breaking into the zeitgeist recently, Docker popped into my sphere from several disparate sources. Seems to me that this is a potential problem-solver for some of the reproducibility and sharing dramas that we have been wrestling with in genomics. Sharing of data sets and versions of analysis software is being tackled in a number of […]... Read more »

  • September 10, 2014
  • 08:00 AM
  • 959 views

Return of Results from Next-gen Sequencing

by Daniel Koboldt in Massgenomics

The rapid adoption of next-gen exome and genome sequencing for clinical use (i.e. with patient DNA) raises some difficult questions about the return of results to patients and their families. In contrast to traditional genetic testing, which usually checks for variants in specific genes, high-throughput sequencing has the potential to reveal a number of secondary […]... Read more »

  • September 10, 2014
  • 05:01 AM
  • 482 views

Donepezil and D-cycloserine rescue behaviours in VPA exposed animals

by Paul Whiteley in Questioning Answers

In a post not-so-long-ago I talked about an interesting piece of research by Ahn and colleagues [1] suggesting that a ketogenic diet might yet hold some promise to "modify complex social behaviors and mitochondrial respiration" affected in the "prenatal valproic acid (VPA) rodent model of ASD [autism spectrum disorder]". The idea being that exposure to valproic acid (valproate) during the nine months that made us might carry some heightened risk for adverse effects on offspring development (see ........ Read more »

  • September 9, 2014
  • 05:10 PM
  • 575 views

Genetics and Running Economy

by Craig Payne in Running Research Junkie

Genetics and Running Economy... Read more »

Bertuzzi R, Pasqua LA, Bueno S, Lima-Silva AE, Matsuda M, Marquezini M, & Saldiva PH. (2014) Is the COL5A1 rs12722 Gene Polymorphism Associated with Running Economy?. PloS one, 9(9). PMID: 25188268  

join us!

Do you write about peer-reviewed research in your blog? Use ResearchBlogging.org to make it easy for your readers — and others from around the world — to find your serious posts about academic research.

If you don't have a blog, you can still use our site to learn about fascinating developments in cutting-edge research from around the world.

Register Now

Research Blogging is powered by SMG Technology.

To learn more, visit seedmediagroup.com.