Post List

All posts; Tags Include "pharmaceutics"

(Modify Search »)

  • April 2, 2013
  • 12:28 PM
  • 1,081 views

Film preparations for oral drug delivery

by Maren Preis in Pharmaceutical Solid State Research Cluster (PSSRC)

Oral films have gained interest in the last couple of years. Films for oral application offer an interesting new approach for drug administration. Active pharmaceutical ingredients (API) can be implemented in thin-sheeted polymer film matrices. These dosage forms are intended to be placed in mouth to dissolve in the saliva without the need of additional liquid and without swallowing of a solid dosage form.... Read more »

Hoffmann EM, Breitenbach A, & Breitkreutz J. (2011) Advances in orodispersible films for drug delivery. Expert opinion on drug delivery, 8(3), 299-316. PMID: 21284577  

Janßen E.M., Schliephacke R,, Breitenbach A,, & Breitkreutz J. (2013) Drug-printing by flexographic printing technology—A new manufacturing process for orodispersible films. International Journal of Pharmaceutics, 441(1-2), 818-825. info:/10.1016/j.ijpharm.2012.12.023

Garsuch V, & Breitkreutz J. (2009) Novel analytical methods for the characterization of oral wafers. European Journal of Pharmaceutics and Biopharmaceutics, 73(1), 195-201. PMID: 19482082  

Woertz K, Tissen C, Kleinebudde P, & Breitkreutz J. (2011) Taste sensing systems (electronic tongues) for pharmaceutical applications. International journal of pharmaceutics, 417(1-2), 256-71. PMID: 21094230  

  • January 29, 2013
  • 08:31 PM
  • 610 views

Microstructure of Film Coated Tablets

by Axel Zeitler in Pharmaceutical Solid State Research Cluster (PSSRC)

Since 2007 when terahertz pulsed imaging (TPI) was first developed to non-destructively measure the coating thickness of pharmaceutical tablets there has been intense research in the PSSRC into how this technique can help improve the quality of pharmaceutical coatings and thus make controlled release technology based on coatings of single dosage forms attractive to industry.... Read more »

Brock, D., Zeitler, J., Funke, A., Knop, K., & Kleinebudde, P. (2012) A comparison of quality control methods for active coating processes. International Journal of Pharmaceutics, 439(1-2), 289-295. DOI: 10.1016/j.ijpharm.2012.09.021  

  • August 18, 2012
  • 09:19 AM
  • 1,895 views

To Treat or Not To Treat... But How?

by Christen Rune Stensvold in Blastocystis Parasite Blog

In the "To Treat of Not To Treat" series (please look up previous post here), we have come to the "...But How?" episode.

Blastocystis may be susceptible to a number of drugs - in vitro. In vitro is not the opposite of in vivo. In vitro just means that the test has been done on an organism that has been isolated from its usual habitat and tested e.g. in a flask, test tube, etc. In the lab, strains can be challenged and manipulated in multiple ways, but there is no guarante........ Read more »

Coyle CM, Varughese J, Weiss LM, & Tanowitz HB. (2012) Blastocystis: to treat or not to treat.. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 54(1), 105-10. PMID: 22075794  

Engsbro AL, & Stensvold CR. (2012) Blastocystis: To Treat Or Not To Treat..But How?. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. PMID: 22893582  

Stensvold CR, Smith HV, Nagel R, Olsen KE, & Traub RJ. (2010) Eradication of Blastocystis carriage with antimicrobials: reality or delusion?. Journal of clinical gastroenterology, 44(2), 85-90. PMID: 19834337  

  • March 3, 2011
  • 08:30 AM
  • 3,232 views

Topical NSAIDs

by Scott Gavura in Science-Based Medicine

I have a mental basket of drugs that I suspect may be placebos. In that basket were the topical versions of non-steroidal anti-inflammatory drugs (NSAIDs). When the first products were commercially marketed over a decade ago, I found the clinical evidence unconvincing, and I suspected that the modestly positive effects were probably due to simply [...]... Read more »

Massey T, Derry S, Moore RA, & McQuay HJ. (2010) Topical NSAIDs for acute pain in adults. Cochrane database of systematic reviews (Online). PMID: 20556778  

Trelle, S., Reichenbach, S., Wandel, S., Hildebrand, P., Tschannen, B., Villiger, P., Egger, M., & Juni, P. (2011) Cardiovascular safety of non-steroidal anti-inflammatory drugs: network meta-analysis. BMJ, 342(jan11 1). DOI: 10.1136/bmj.c7086  

Haroutiunian, S., Drennan, D., & Lipman, A. (2010) Topical NSAID Therapy for Musculoskeletal Pain. Pain Medicine, 11(4), 535-549. DOI: 10.1111/j.1526-4637.2010.00809.x  

  • December 9, 2010
  • 08:30 AM
  • 1,769 views

Good Idea, Bad Execution: Dosing Errors, A Preventable Harm

by Scott in Science-Based Pharmacy

Crossposted at Science-Based Medicine, today’s post expands on a prior SBP post. Our desire to practice in a science-based way can face many hurdles, and can even be thwarted at the last possible moment – in the form of dosing errors. The workup may have been comprehensive, the diagnosis could be correct, the most clinically [...]... Read more »

Yin HS, Mendelsohn AL, Wolf MS, Parker RM, Fierman A, van Schaick L, Bazan IS, Kline MD, & Dreyer BP. (2010) Parents' medication administration errors: role of dosing instruments and health literacy. Archives of pediatrics , 164(2), 181-6. PMID: 20124148  

  • December 9, 2010
  • 08:00 AM
  • 2,570 views

Good Idea, Bad Execution: Dosing Errors, A Preventable Harm

by Scott Gavura in Science-Based Medicine

We spend a lot time at SBM discussing different elements of the art and science of medicine, and how we believe that practice can be improve. Yet our science-based intentions can be thwarted at the last possible moment – in the form of dosing errors. The workup may have been comprehensive, the diagnosis could be [...]... Read more »

Yin HS, Mendelsohn AL, Wolf MS, Parker RM, Fierman A, van Schaick L, Bazan IS, Kline MD, & Dreyer BP. (2010) Parents' medication administration errors: role of dosing instruments and health literacy. Archives of pediatrics , 164(2), 181-6. PMID: 20124148  

join us!

Do you write about peer-reviewed research in your blog? Use ResearchBlogging.org to make it easy for your readers — and others from around the world — to find your serious posts about academic research.

If you don't have a blog, you can still use our site to learn about fascinating developments in cutting-edge research from around the world.

Register Now

Research Blogging is powered by SRI Technology.

To learn more, visit http://selfregulationinstitute.org/.