Dr. Jekyll

910 posts · 581,087 views

I have big dreams [don't we all?], I want to change the world. That is why I started Lunatic Laboratories, a little project that I hope will one day be a household name. Who knows, maybe it will work out, but even if it doesn't, at least it will be fun to try.

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  • September 9, 2016
  • 02:16 PM
  • 399 views

Study could herald new treatment for muscular dystrophy

by Dr. Jekyll in Lunatic Laboratories

New research has shown that the corticosteroid deflazacort is a safe and effective treatment for Duchenne muscular dystrophy. The findings could pave the way for first U.S.-approved treatment for the disease.

... Read more »

Griggs, R., Miller, J., Greenberg, C., Fehlings, D., Pestronk, A., Mendell, J., Moxley, R., King, W., Kissel, J., Cwik, V.... (2016) Efficacy and safety of deflazacort vs prednisone and placebo for Duchenne muscular dystrophy. Neurology, 10. DOI: 10.1212/WNL.0000000000003217  

  • September 8, 2016
  • 04:28 PM
  • 423 views

How new experiences boost memory formation

by Dr. Jekyll in Lunatic Laboratories

Most people remember where they were when the twin towers collapsed in New York ... new research reveals why that may be the case. The study has shed new light on the biological mechanisms that drive the process, known as flashbulb memory.

... Read more »

Takeuchi, T., Duszkiewicz, A., Sonneborn, A., Spooner, P., Yamasaki, M., Watanabe, M., Smith, C., Fernández, G., Deisseroth, K., Greene, R.... (2016) Locus coeruleus and dopaminergic consolidation of everyday memory. Nature. DOI: 10.1038/nature19325  

  • September 7, 2016
  • 02:15 PM
  • 508 views

Antimicrobial chemicals found with antibiotic-resistance genes in indoor dust

by Dr. Jekyll in Lunatic Laboratories

Researchers have found links between the levels of antimicrobial chemicals and antibiotic-resistance genes in the dust of an aging building used for athletics and academics. One of the antimicrobials seen in the study is triclosan, a commonly used antibacterial ingredient in many personal care products.

... Read more »

Hartmann, E., Hickey, R., Hsu, T., Betancourt Román, C., Chen, J., Schwager, R., Kline, J., Brown, G., Halden, R., Huttenhower, C.... (2016) Antimicrobial Chemicals Are Associated with Elevated Antibiotic Resistance Genes in the Indoor Dust Microbiome. Environmental Science . DOI: 10.1021/acs.est.6b00262  

  • September 6, 2016
  • 01:26 PM
  • 545 views

Body heat as a power source

by Dr. Jekyll in Lunatic Laboratories

Electronics integrated into textiles are gaining in popularity: Systems like smartphone displays in a sleeve or sensors to detect physical performance in athletic wear have already been produced. The main problem with these systems tends to be the lack of a comfortable, equally wearable source of power. Chinese scientists are now aiming to obtain the necessary energy from body heat by introducing a flexible, wearable thermocell based on two different gel electrolytes.

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Yang, P., Liu, K., Chen, Q., Mo, X., Zhou, Y., Li, S., Feng, G., & Zhou, J. (2016) Wearable Thermocells Based on Gel Electrolytes for the Utilization of Body Heat. Angewandte Chemie International Edition. DOI: 10.1002/anie.201606314  

  • September 5, 2016
  • 02:34 PM
  • 525 views

Drugs in the water? Don't blame the students

by Dr. Jekyll in Lunatic Laboratories

With nearly sixty percent of American adults now taking prescription medications--from antidepressants to cholesterol treatments--there is growing concern about how many drugs are flowing through wastewater treatment facilities and into rivers and lakes. Research confirms that pharmaceutical pollution can cause damage to fish and other ecological problems--and may pose risks to human health too.

... Read more »

  • September 4, 2016
  • 03:25 PM
  • 453 views

Parents' math skills 'rub off' on their children

by Dr. Jekyll in Lunatic Laboratories

Parents who excel at math produce children who excel at math. This is according to a recently released study, which shows a distinct transfer of math skills from parent to child. The study specifically explored intergenerational transmission--the concept of parental influence on an offspring's behavior or psychology--in mathematical capabilities.

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Braham, E., & Libertus, M. (2016) Intergenerational associations in numerical approximation and mathematical abilities. Developmental Science. DOI: 10.1111/desc.12436  

  • September 3, 2016
  • 03:04 PM
  • 540 views

The Genesis Project: New life on exoplanets

by Dr. Jekyll in Lunatic Laboratories

Can life be brought to celestial bodies outside our solar system, which are not permanently inhabitable? A new essay that has been published is trying to deal with this question. Over the last several years, the search for exoplanets has shown that very different types exist leading to new questions and a variety of possible answers.

... Read more »

Claudius Gros. (2016) Developing Ecospheres on Transiently Habitable Planets: The Genesis Project. Astrophysics and Space Science. arXiv: 1608.06087v2

  • September 2, 2016
  • 02:21 PM
  • 476 views

Babies chew on subtle social, cultural cues at mealtime

by Dr. Jekyll in Lunatic Laboratories

At the dinner table, babies do a lot more than play with their sippy cups, new research suggests. Babies pay close attention to what food is being eaten around them - and especially who is eating it. The study adds evidence to a growing body of research suggesting even very young children think in sophisticated ways about subtle social cues.

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Liberman, Z., Woodward, A., Sullivan, K., & Kinzler, K. (2016) Early emerging system for reasoning about the social nature of food. Proceedings of the National Academy of Sciences, 113(34), 9480-9485. DOI: 10.1073/pnas.1605456113  

  • September 1, 2016
  • 01:36 PM
  • 422 views

Trauma's epigenetic fingerprint observed in children of Holocaust survivors

by Dr. Jekyll in Lunatic Laboratories

The children of traumatized people have long been known to be at increased risk for posttraumatic stress disorder (PTSD), and mood and anxiety disorders. However, there are very few opportunities to examine biologic alterations in the context of a watershed trauma in exposed people and their adult children born after the event.

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Yehuda, R., Daskalakis, N., Bierer, L., Bader, H., Klengel, T., Holsboer, F., & Binder, E. (2016) Holocaust Exposure Induced Intergenerational Effects on FKBP5 Methylation. Biological Psychiatry, 80(5), 372-380. DOI: 10.1016/j.biopsych.2015.08.005  

  • August 31, 2016
  • 02:55 PM
  • 445 views

Scientists show that a 'Superman' disguise could actually work

by Dr. Jekyll in Lunatic Laboratories

Ever think it's silly that people don't recognize Clark Kent is actually Superman? Well as it turns out, glasses are actually a fairly good way to disguise yourself. In fact, researchers have shown that small alterations to a person's appearance, such as wearing glasses, can significantly hinder positive facial identification.

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Kramer, R., & Ritchie, K. (2016) Disguising Superman: How Glasses Affect Unfamiliar Face Matching. Applied Cognitive Psychology. DOI: 10.1002/acp.3261  

  • August 30, 2016
  • 04:18 PM
  • 386 views

Caffeine reverts memory deficits by normalizing stress responses in the brain

by Dr. Jekyll in Lunatic Laboratories

A new study describes the mechanism by which caffeine counteracts age-related cognitive deficits in animals. The international teams showed that the abnormal expression of a particular receptor - the adenosine A2A, target for caffeine - in the brain of rats induces an aging-like profile namely memory impairments linked to the loss of stress controlling mechanisms.

... Read more »

  • August 29, 2016
  • 02:49 PM
  • 364 views

Use it or lose it: Stopping exercise decreases brain blood flow

by Dr. Jekyll in Lunatic Laboratories

We all know that we can quickly lose cardiovascular endurance if we stop exercising for a few weeks, but what impact does the cessation of exercise have on our brains? New research examined cerebral blood flow in healthy, physically fit older adults (ages 50-80 years) before and after a 10-day period during which they stopped all exercise.

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Alfini, A., Weiss, L., Leitner, B., Smith, T., Hagberg, J., & Smith, J. (2016) Hippocampal and Cerebral Blood Flow after Exercise Cessation in Master Athletes. Frontiers in Aging Neuroscience. DOI: 10.3389/fnagi.2016.00184  

  • August 28, 2016
  • 02:29 PM
  • 363 views

A visual nudge can disrupt recall of what things look like

by Dr. Jekyll in Lunatic Laboratories

Interfering with your vision makes it harder to describe what you know about the appearance of even common objects, according to researchers. This connection between visual knowledge and visual perception challenges widely held theories that visual information about the world -- that alligators are green and have long tails, for example -- is stored abstractly, as a list of facts, divorced from the visual experience of seeing an alligator.... Read more »

Edmiston, P., & Lupyan, G. (2015) Visual interference disrupts visual and only visual knowledge. Journal of Vision, 15(12), 10. DOI: 10.1167/15.12.10  

  • August 27, 2016
  • 01:27 PM
  • 383 views

Researchers report new Zika complication

by Dr. Jekyll in Lunatic Laboratories

If zika didn't seem scary enough in the media, there is new data showing that there could be a new neurological complication of infection with the Zika virus.

... Read more »

Medina, M., England, J., Lorenzana, I., Medina-Montoya, M., Alvarado, D., De Bastos, M., Fontiveros, S., Sierra, M., & Contreras, F. (2016) Zika virus associated with sensory polyneuropathy. Journal of the Neurological Sciences. DOI: 10.1016/j.jns.2016.08.044  

  • August 26, 2016
  • 02:20 PM
  • 372 views

Next steps in understanding brain function

by Dr. Jekyll in Lunatic Laboratories

The most complex piece of matter in the known universe is the brain. Neuroscientists have recently taken on the challenge to understand brain function from its intricate anatomy and structure. There is no sure way to go about it, and researchers in Madrid proposed a solution to the problem.

... Read more »

  • August 25, 2016
  • 02:50 PM
  • 460 views

The relationship between low physical activity and psychotic symptoms

by Dr. Jekyll in Lunatic Laboratories

Physical activity can help reduce cardiovascular disease and premature mortality in people with psychological problems. However, there is limited data on exercise in people with serious mental disorders, especially from low- and middle-income countries. This study explored whether complying with the World Health Organization recommendations of 150 minutes of moderate-vigorous exercise per week is related to psychotic symptoms or the diagnosis of a psychosis.

... Read more »

Brendon Stubbs, Ai Koyanagi, Felipe Schuch, Joseph Firth, Simon Rosenbaum, Fiona Gaughran, James Mugisha, & Davy Vancampfort. (2016) Physical Activity Levels and Psychosis: A Mediation Analysis of Factors Influencing Physical Activity Target Achievement Among 204 186 People Across 46 Low- and Middle-Income Countries. Schizophrenia bulletin . info:/10.1093/schbul/sbw111

  • August 24, 2016
  • 02:51 PM
  • 494 views

How long do you want to live? Your expectations for old age matter

by Dr. Jekyll in Lunatic Laboratories

Why do some people want to live a very long time, while others would prefer to die relatively young? In a latest study, a team of researchers investigated how long young and middle-aged adults in the United States say they want to live in relation to a number of personal characteristics. The results showed that more than one out of six people would prefer to die younger than age 80, before reaching average life expectancy.

... Read more »

  • August 23, 2016
  • 02:31 PM
  • 479 views

Too much activity in certain areas of the brain is bad for memory and attention

by Dr. Jekyll in Lunatic Laboratories

Neurons in the brain interact by sending each other chemical messages, so-called neurotransmitters. Gamma-aminobutyric acid (GABA) is the most common inhibitory neurotransmitter, which is important to restrain neural activity, preventing neurons from getting too trigger-happy and from firing too much or responding to irrelevant stimuli.

... Read more »

  • August 22, 2016
  • 03:00 PM
  • 406 views

Stroke-like brain damage is reduced in mice injected with omega-3s

by Dr. Jekyll in Lunatic Laboratories

A stroke can happen at any age, and as with anything that involves the brain, a few seconds can be life altering. Usually the rule is time lost is brain lost, but there might be some good news regarding that, researchers found that omega-3 fatty acids reduced brain damage in a neonatal mouse model of stroke.

... Read more »

  • August 21, 2016
  • 02:53 PM
  • 458 views

In cells, some oxidants are needed

by Dr. Jekyll in Lunatic Laboratories

Within our bodies, high levels of reactive forms of oxygen can damage proteins and contribute to diabetic complications and many other diseases. But some studies are showing that these reactive oxygen species (ROS) molecules sometimes can aid in maintaining health--findings now boosted by a surprising discovery by researchers.

... Read more »

Hourihan, J., Moronetti Mazzeo, L., Fernández-Cárdenas, L., & Blackwell, T. (2016) Cysteine Sulfenylation Directs IRE-1 to Activate the SKN-1/Nrf2 Antioxidant Response. Molecular Cell, 63(4), 553-566. DOI: 10.1016/j.molcel.2016.07.019  

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