Serious question: has the peer review system at the PLOS journals been doing a less-than-stellar job when it comes to evaluating complementary and alternative medicine (CAM) research for publication? If the answer is 'yes', why? Or if 'no', how does a paper like this go through PLOS ONE without some serious revisions?... Read more »
Zhao, X., Hu, H., Li, J., Shang, H., Zheng, H., Niu, J., Shi, X., & Wang, S. (2015) Is Acupuncture Effective for Hypertension? A Systematic Review and Meta-Analysis. PLOS ONE, 10(7). DOI: 10.1371/journal.pone.0127019
Five men with complete motor paralysis were able to voluntarily generate step-like movements thanks to a new strategy that non-invasively delivers electrical stimulation to their spinal cords. The strategy, called transcutaneous stimulation, delivers electrical current to the spinal cord by way of electrodes strategically placed on the skin of the lower back.... Read more »
Gerasimenko, Y., Lu, D., Modaber, M., Zdunowski, S., Gad, P., Sayenko, D., Morikawa, E., Haakana, P., Ferguson, A., Roy, R.... (2015) Noninvasive Reactivation of Motor Descending Control after Paralysis. Journal of Neurotrauma, 2147483647. DOI: 10.1089/neu.2015.4008
Cupriavidus metallidurans (roughly translated: lover of copper, enduring metal) is a bacterium of the class Betaproteobacteria known for its ability to withstand high concentrations of numerous metals that would be toxic to most other living things. These metals, which include Ag, Au, Bi, Cd, Co, Cr, Cs, Cu, Hg, Ni, Pb, Sr, Tl, U, and Zn, tend to cause problems for bacterial cells by binding to DNA or proteins, which can disrupt important stuff like obtaining energy or reproducing.The bacterium ........ Read more »
Phillips G, Reith F, Qualls C, Ali AM, Spilde M, & Appenzeller O. (2010) Bacterial deposition of gold on hair: Archeological, forensic and toxicological implications. PloS One, 5(2). PMID: 20174476
Wiesemann N, Mohr J, Grosse C, Herzberg M, Hause G, Reith F, & Nies DH. (2013) Influence of copper resistance determinants on gold transformation by Cupriavidus metallidurans strain CH34. Journal of Bacteriology, 195(10), 2298-308. PMID: 23475973
De novo mutations — sequence variants that are present in a child but absent from both parents — are an important source of human genetic variation. I think it’s reasonable to say that most of the 3-4 million variants in any individual’s genome arose, once upon a time, as de novo mutations in his or her ancestors. […]... Read more »
Francioli LC, Polak PP, Koren A, Menelaou A, Chun S, Renkens I, Genome of the Netherlands Consortium, van Duijn CM, Swertz M, Wijmenga C.... (2015) Genome-wide patterns and properties of de novo mutations in humans. Nature genetics, 47(7), 822-6. PMID: 25985141
A quote to begin today's post:"Across each population with different kinds of ascertainment, there was a consistent and statistically significant increased prevalence of IBD [inflammatory bowel disease] in patients with ASD [autism spectrum disorder] than their respective controls and nationally reported rates for pediatric IBD."That was the conclusion reached in the paper published by Finale Doshi-Velez and colleagues  including one very notable name on the authorship list, Is........ Read more »
Doshi-Velez F, Avillach P, Palmer N, Bousvaros A, Ge Y, Fox K, Steinberg G, Spettell C, Juster I, & Kohane I. (2015) Prevalence of Inflammatory Bowel Disease Among Patients with Autism Spectrum Disorders. Inflammatory bowel diseases. PMID: 26218138
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