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  • July 30, 2015
  • 04:10 PM
  • 4 views

Lax standards at PLOS One for peer review of CAM research papers?

by Kausik Datta in In Scientio Veritas

Serious question: has the peer review system at the PLOS journals been doing a less-than-stellar job when it comes to evaluating complementary and alternative medicine (CAM) research for publication? If the answer is 'yes', why? Or if 'no', how does a paper like this go through PLOS ONE without some serious revisions?... Read more »

  • July 30, 2015
  • 01:55 PM
  • 12 views

Paralyzed men move legs with new non-invasive spinal cord stimulation

by Dr. Jekyll in Lunatic Laboratories

Five men with complete motor paralysis were able to voluntarily generate step-like movements thanks to a new strategy that non-invasively delivers electrical stimulation to their spinal cords. The strategy, called transcutaneous stimulation, delivers electrical current to the spinal cord by way of electrodes strategically placed on the skin of the lower back.... Read more »

Gerasimenko, Y., Lu, D., Modaber, M., Zdunowski, S., Gad, P., Sayenko, D., Morikawa, E., Haakana, P., Ferguson, A., Roy, R.... (2015) Noninvasive Reactivation of Motor Descending Control after Paralysis. Journal of Neurotrauma, 2147483647. DOI: 10.1089/neu.2015.4008  

  • July 30, 2015
  • 01:10 PM
  • 14 views

A tough bacterium that lives in poisoned soils and pulls gold out of water

by Rosin Cerate in Rosin Cerate

Cupriavidus metallidurans (roughly translated: lover of copper, enduring metal) is a bacterium of the class Betaproteobacteria known for its ability to withstand high concentrations of numerous metals that would be toxic to most other living things. These metals, which include Ag, Au, Bi, Cd, Co, Cr, Cs, Cu, Hg, Ni, Pb, Sr, Tl, U, and Zn, tend to cause problems for bacterial cells by binding to DNA or proteins, which can disrupt important stuff like obtaining energy or reproducing.The bacterium ........ Read more »

  • July 30, 2015
  • 08:00 AM
  • 16 views

New Insights into Human De Novo Mutations

by Daniel Koboldt in Massgenomics

De novo mutations — sequence variants that are present in a child but absent from both parents — are an important source of human genetic variation. I think it’s reasonable to say that most of the 3-4¬†million variants in any individual’s genome arose, once upon a time, as de novo mutations in his or her¬†ancestors. […]... Read more »

Francioli LC, Polak PP, Koren A, Menelaou A, Chun S, Renkens I, Genome of the Netherlands Consortium, van Duijn CM, Swertz M, Wijmenga C.... (2015) Genome-wide patterns and properties of de novo mutations in humans. Nature genetics, 47(7), 822-6. PMID: 25985141  

  • July 30, 2015
  • 04:06 AM
  • 20 views

Inflammatory bowel disease and autism: increased prevalence

by Paul Whiteley in Questioning Answers

A quote to begin today's post:"Across each population with different kinds of ascertainment, there was a consistent and statistically significant increased prevalence of IBD [inflammatory bowel disease] in patients with ASD [autism spectrum disorder] than their respective controls and nationally reported rates for pediatric IBD."That was the conclusion reached in the paper published by Finale Doshi-Velez and colleagues [1] including one very notable name on the authorship list, Is........ Read more »

Doshi-Velez F, Avillach P, Palmer N, Bousvaros A, Ge Y, Fox K, Steinberg G, Spettell C, Juster I, & Kohane I. (2015) Prevalence of Inflammatory Bowel Disease Among Patients with Autism Spectrum Disorders. Inflammatory bowel diseases. PMID: 26218138  

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