New research shows that infections can impair your cognitive ability measured on an IQ scale. The study is the largest of its kind to date, and it shows a clear correlation between infection levels and impaired cognition. Anyone can suffer from an infection, for example in their stomach, urinary tract or skin. However, a new Danish study shows that a patient’s distress does not necessarily end once the infection has been treated.... Read more »
Benros ME, Sørensen HJ, Nielsen PR, Nordentoft M, Mortensen PB, & Petersen L. (2015) The Association between Infections and General Cognitive Ability in Young Men - A Nationwide Study. PloS one, 10(5). PMID: 25970427
Spatial Ecosystem models can be useful but need to be validated with data. Our study validates for the first time the spatial version of the commonly used Ecopath with Ecosim ecosystem modelling suite. We find that spatial distribution of fish species is well predicted by the model, but fishing effort distribution is not.
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Romagnoni, G., Mackinson, S., Hong, J., & Eikeset, A. (2015) The Ecospace model applied to the North Sea: Evaluating spatial predictions with fish biomass and fishing effort data. Ecological Modelling, 50-60. DOI: 10.1016/j.ecolmodel.2014.12.016
International Clinical Trial day (May 20th) celebrates the medical advances as a result of clinical trials. Clinical trials are essential to ensure drug safety and efficacy, and the recent increase in the development of orphan drugs has led to an increase in rare disease clinical trials. The nature of rare diseases creates specific challenges for clinical trial design and patient recruitment.... Read more »
Bell SA, & Tudur Smith C. (2014) A comparison of interventional clinical trials in rare versus non-rare diseases: an analysis of ClinicalTrials.gov. Orphanet journal of rare diseases, 170. PMID: 25427578
Gagne JJ, Thompson L, O'Keefe K, & Kesselheim AS. (2014) Innovative research methods for studying treatments for rare diseases: methodological review. BMJ (Clinical research ed.). PMID: 25422272
"These results provide evidence that gains from early intensive intervention are maintained 2 years later. Notably, core autism symptoms improved in the ESDM [Early Start Denver Model] group over the follow-up period relative to the COM [community-intervention-as-usual] group."Those were some of the conclusions reported in amongst the potentially very important results from Annette Estes and colleagues  looking at "the sustained effects of early intervention" followin........ Read more »
Annette Estes, Jeffrey Munson, Sally J. Rogers, Jessica Greenson, Jamie Winter, & Geraldine Dawson. (2015) Long-Term Outcomes of Early Intervention in 6-Year-Old Children With Autism Spectrum Disorder. J Am Acad Child Adolesc Psychiatry. info:/10.1016/j.jaac.2015.04.005
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