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  • March 27, 2015
  • 06:02 AM
  • 6 views

Inflammation impairs social cognitive processing

by Paul Whiteley in Questioning Answers

A quote to begin: "acute inflammation can lead to decreases in the ability to accurately and reliably comprehend emotional information from others."It comes from the article published by Mona Moieni and colleagues [1] who examined a concept familiar to many people with a connection to autism either personally or professionally: Theory of Mind (ToM). Rather interestingly, Moieni et al "examined whether exposure to an experimental inflammatory challenge led to changes in ToM." Inflammato........ Read more »

  • March 27, 2015
  • 01:22 AM
  • 10 views

Is a trauma focus truly needed in PTSD treatment?

by Eva Alisic in Trauma Recovery

For treatment of Posttraumatic Stress Disorder to be effective, is it really necessary to focus on the trauma itself? ... Read more »

Barlow DH, Bullis JR, Comer JS, & Ametaj AA. (2013) Evidence-based psychological treatments: an update and a way forward. Annual review of clinical psychology, 1-27. PMID: 23245338  

Watts BV, Schnurr PP, Mayo L, Young-Xu Y, Weeks WB, & Friedman MJ. (2013) Meta-analysis of the efficacy of treatments for posttraumatic stress disorder. The Journal of clinical psychiatry. PMID: 23842024  

Wampold BE, Imel ZE, Laska KM, Benish S, Miller SD, Flückiger C, Del Re AC, Baardseth TP, & Budge S. (2010) Determining what works in the treatment of PTSD. Clinical psychology review, 923-33. PMID: 20638168  

  • March 26, 2015
  • 02:20 PM
  • 25 views

High-fat diet causes brain inflammation and alters behavior

by Dr. Jekyll in Lunatic Laboratories

We hear in the media all the time, obesity is effecting our health. In most cases when we talk obesity we are talking about heart disease, sedentary activity, or chronic overeating. But what if a high-fat diet — regardless of obesity — has more than just an affect on your waistline? What if the consumption of fatty foods can change your behavior and your brain?... Read more »

Bruce-Keller, A., Salbaum, J., Luo, M., Blanchard, E., Taylor, C., Welsh, D., & Berthoud, H. (2015) Obese-type Gut Microbiota Induce Neurobehavioral Changes in the Absence of Obesity. Biological Psychiatry, 77(7), 607-615. DOI: 10.1016/j.biopsych.2014.07.012  

  • March 26, 2015
  • 11:17 AM
  • 18 views

Parenting Moderates Childhood Brain Stress Response

by William Yates, M.D. in Brain Posts

Child brain development benefits from a positive parenting style and environment.The mechanism for this positive effect is unclear but moderation of the stress response in the growing child is an area of research interest.Haroon Sheikh and colleagues from the University of Ontario in Canada recently published results on a study of parenting and brain development in children.In their study, a cohort of 46 six year old girls underwent brain imaging using a technique known as diffusion tensor imagi........ Read more »

  • March 26, 2015
  • 08:54 AM
  • 23 views

Angelina Jolie’s Preemptive Strike Against Cancer

by Bill Sullivan in The 'Scope

Actress Angelina Jolie has parts of her body surgically removed in an effort to avoid cancer. Brave or crazy?
... Read more »

  • March 26, 2015
  • 07:39 AM
  • 26 views

Autism increases risk of nonaffective psychotic disorder and bipolar disorder

by Paul Whiteley in Questioning Answers

Published at the same time and in the same journal as the 'MoBa does bowel issues in autism' paper from Bresnahan and colleagues [1], the study results from Jean-Paul Selten et al [2] reporting that "A diagnosis of ASD [autism spectrum disorder] is associated with a substantially increased risk for NAPD [nonaffective psychotic disorder] and BD [bipolar disorder]" has, at the time of writing this post, received little or no press attention in comparison despite ........ Read more »

  • March 26, 2015
  • 07:00 AM
  • 27 views

http://www.united-academics.org/magazine/health-medicine/coffees-dirty-secret-like-carcinogens-with-that/

by Elisabeth Buhl Thubron in United Academics

Furans are coffee’s dirty little secret. Although we can thank them for the pleasant aroma and delicious flavour of freshly brewed coffee, furans have been labelled as a possible human carcinogen (cause of cancer) in disguise by food safety agencies. How many are in there
depends on how you like your cup of Joe.... Read more »

  • March 26, 2015
  • 12:38 AM
  • 43 views

The Smell of Stress and Fear

by Aurametrix team in Olfactics and Diagnostics

Can we recognize if people around us are stressed, anxious or fearful without observing their facial expressions, body language and actions or hearing their voice and messages? Can we understand if we are stressed ourselves without assessing our heart rate, blood pressure, noticing dry throat, sweating, drops or surges in energy? Yes, we can - by using our nose - as humans, too, recognize and transmit their emotions through chemical senses.When we are stressed or panic we become more sensit........ Read more »

Haegler, K., Zernecke, R., Kleemann, A., Albrecht, J., Pollatos, O., Brückmann, H., & Wiesmann, M. (2010) No fear no risk! Human risk behavior is affected by chemosensory anxiety signals. Neuropsychologia, 48(13), 3901-3908. DOI: 10.1016/j.neuropsychologia.2010.09.019  

Prehn-Kristensen A, Wiesner C, Bergmann TO, Wolff S, Jansen O, Mehdorn HM, Ferstl R, & Pause BM. (2009) Induction of empathy by the smell of anxiety. PloS one, 4(6). PMID: 19551135  

  • March 25, 2015
  • 05:59 PM
  • 36 views

Immunotherapy, a promising new treatment of Alzheimer’s disease

by Dr. Jekyll in Lunatic Laboratories

Alzheimer’s disease, it slowly takes things away from the person without giving anything back. Right now there is no cure and at best we can slow the progression in some cases. Time is always a factor and no two cases are the same. However, new treatments are in the works and a new study has revealed that a single dose of an immunotherapy reverses memory problems in an animal model of Alzheimer’s disease.... Read more »

  • March 25, 2015
  • 05:57 PM
  • 32 views

MoBa does bowel issues in autism

by Paul Whiteley in Questioning Answers

'MoBa' in the title of this post, refers to the Norwegian Mother and Child Cohort Study and a handy resource which has already impacted on autism research (see here for example).Now MoBa has turned its epidemiological clout to an issue which less and less is encountering scientific resistance: are gastrointestinal (GI) symptoms over-represented when it comes to a diagnosis of autism? Further, when do such bowel issues start to present?The answer, shown in the paper by Michaeline B........ Read more »

Bresnahan, M., Hornig, M., Schultz, A., Gunnes, N., Hirtz, D., Lie, K., Magnus, P., Reichborn-Kjennerud, T., Roth, C., Schjølberg, S.... (2015) Association of Maternal Report of Infant and Toddler Gastrointestinal Symptoms With Autism. JAMA Psychiatry. DOI: 10.1001/jamapsychiatry.2014.3034  

  • March 25, 2015
  • 01:03 PM
  • 36 views

Cracking the blood-brain barrier with magnetic nanoparticles

by Dr. Jekyll in Lunatic Laboratories

The blood-brain barrier, the thorn in the side of medicine. It makes using drugs directed for the brain ineffective at best and unusable at worst. This barrier runs inside almost all vessels in the brain and protects it from elements circulating in the blood that may be toxic to the brain. This barrier means that currently 98% of therapeutic molecules are also unable to cross to the brain. However, researchers now say magnetic nanoparticles can open the blood-brain barrier and deliver molecules ........ Read more »

  • March 25, 2015
  • 10:37 AM
  • 36 views

Parental Education As Risk Factor For Eating Disorders

by William Yates, M.D. in Brain Posts

Genetic and environmental risk factors contribute to the risk for anorexia nervosa and other eating disorders.Known risk factors for anorexia nervosa include female gender, young age, family member with anorexia nervosa, weight loss, and participation in weight sensitive sports or activities, i.e. gymnastics, dancing.There has also been evidence that anorexia nervosa is more common in higher socioeconomic classes. This finding has made it one of the few brain disorders more common with this cate........ Read more »

  • March 25, 2015
  • 05:33 AM
  • 40 views

Autism and depression: interlinked?

by Paul Whiteley in Questioning Answers

"A possible implication is that interventions aimed at either autism symptoms or symptoms of depression may improve the other."That was the intriguing statement made by Per Normann Andersen and colleagues [1] who "investigated the course of and association among changes in autism symptoms, depression symptoms and executive functions (EF) in children with high-functioning autism (HFA)." Aside from frowning a little at the mention of the concept of 'high-functioning' I assume to denote those ........ Read more »

  • March 24, 2015
  • 11:46 PM
  • 32 views

Electric Lights Disrupts Human Circadian Rhythm

by Marie Benz in MedicalResearch.com

MedicalResearch.com Medical Research Interviews and News
MedicalResearch.com Interview with: Richard G. Stevens, Ph.D., Professor, Cancer Epidemiologist UConn Health   Medical Research: What is the background for this study? What are the main findings? Dr. Stevens: Since first introducing the concept of a possible connection between exposure … Continue reading →
The post Electric Lights Disrupts Human Circadian Rhythm appeared first on MedicalResearch.com Medical Research Interviews........ Read more »

MedicalResearch.com Interview with:, & Richard G. Stevens, Ph.D. (2015) Electric Lights Disrupts Human Circadian Rhythm. MedicalResearch.com. info:/

  • March 24, 2015
  • 02:13 PM
  • 17 views

Women’s Sexual Desire May Be Sleep Dependent

by Marie Benz in MedicalResearch.com

MedicalResearch.com Medical Research Interviews and News
MedicalResearch.com Interview with: David A Kalmbach, PhD Sleep and Circadian Research Laboratory Department of Psychiatry University of Michigan Medical School Medical Research: What is the background for this study? What are the main findings? Dr. Kalmbach: As it happens, my … Continue reading →
The post Women’s Sexual Desire May Be Sleep Dependent appeared first on MedicalResearch.com Medical Research Interviews and Ne........ Read more »

MedicalResearch.com Interview with:, & David A Kalmbach, PhD. (2015) Women's Sexual Desire May Be Sleep Dependent. MedicalResearch.com. info:/

  • March 24, 2015
  • 01:44 PM
  • 39 views

Milk, not just for your bones, for your brain

by Dr. Jekyll in Lunatic Laboratories

Milk, depending on who you ask it’s either great or the devil. In the US drinking milk is common; not so much in other parts of the world. This has lead to questions about why we even drink milk and how real its reported health claims actually are. Well new research has found a correlation between milk consumption and the levels of a naturally-occurring antioxidant called glutathione in the brain in older, healthy adults.... Read more »

Choi, I., Lee, P., Denney, D., Spaeth, K., Nast, O., Ptomey, L., Roth, A., Lierman, J., & Sullivan, D. (2014) Dairy intake is associated with brain glutathione concentration in older adults. American Journal of Clinical Nutrition, 101(2), 287-293. DOI: 10.3945/ajcn.114.096701  

  • March 24, 2015
  • 07:54 AM
  • 36 views

Cardiovascular Changes Shown in Living Kidney Donors

by Cristy at Living Donor 101 in Living Donors Are People Too

It’s well established that a reduction in kidney function (GFR) significantly increases one’s risk of cardiovascular disease and death. It’s all known that folks in all stages of chronic kidney disease are at risk for heart troubles. Finally, a few researchers got together and decided to look at how living kidney donor’s hearts change post-nephrectomy. …
Continue reading »
The post Cardiovascular Changes Shown in Living Kidney Donors appeared first on Living D........ Read more »

Moody, W., Ferro, C., Edwards, N., Chue, C., Lin, E., Taylor, R., Cockwell, P., Steeds, R., & Townend, J. (2015) EFFECTS OF NEPHRECTOMY ON CARDIOVASCULAR STRUCTURE AND FUNCTION IN LIVING KIDNEY DONORS. Journal of the American College of Cardiology, 65(10). DOI: 10.1016/S0735-1097(15)62150-7  

  • March 24, 2015
  • 05:37 AM
  • 43 views

More extremes of a limiting diet and autism

by Paul Whiteley in Questioning Answers

In a previous post a while back, I discussed some examples in the peer-reviewed literature of where a self-limiting diet in the extreme can lead to with autism in mind. Today, I'm adding a further example of what food faddism might mean, to further forward the point that "a low threshold for vitamin level testing should be undertaken in autistic spectrum disorder cases, highlighting the importance of enquiring about dietary habits."That last quote comes from the paper in question by Emma Du........ Read more »

  • March 23, 2015
  • 03:02 PM
  • 47 views

The neurological basis for anorexia nervosa

by Dr. Jekyll in Lunatic Laboratories

Most of us know about dieting, and if not first hand, have seen in the news or from friends how hard sticking to a diet long-term can be. This is because adults (regardless of their weight_ resolve to lose weight. Yet, more often than not, that chocolate lava cake is too enticing and that resolve vanishes. This behavior is normal because hunger increases the intensity of food rewards. Yet, individuals with anorexia nervosa (AN), despite their state of starvation, are able to ignore such food-rel........ Read more »

Wierenga, C., Bischoff-Grethe, A., Melrose, A., Irvine, Z., Torres, L., Bailer, U., Simmons, A., Fudge, J., McClure, S., Ely, A.... (2015) Hunger Does Not Motivate Reward in Women Remitted from Anorexia Nervosa. Biological Psychiatry, 77(7), 642-652. DOI: 10.1016/j.biopsych.2014.09.024  

  • March 23, 2015
  • 11:01 AM
  • 52 views

Smoking in Pregnancy and Child Brain Development

by William Yates, M.D. in Brain Posts

Smoking during pregnancy produces significant and diverse effects on prenatal development.These adverse effects include dysfunction in prenatal and early childhood brain development.Hanan El Marroun and colleagues from the Netherlands recently published an important childhood brain imaging study of smoking during pregnancy.One hundred and thirteen children exposed to tobacco during pregnancy were compared to a control group of unexposed children.Both groups of children between 6 and 8 years of a........ Read more »

El Marroun H, Schmidt MN, Franken IH, Jaddoe VW, Hofman A, van der Lugt A, Verhulst FC, Tiemeier H, & White T. (2014) Prenatal tobacco exposure and brain morphology: a prospective study in young children. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 39(4), 792-800. PMID: 24096296  

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