by Shawn Radcliffe in Branáin
If you are dealing with excessive daytime sleepiness, gain an extra boost of alertness with tips from these recent research studies.... Read more »
Reid, K., Baron, K., Lu, B., Naylor, E., Wolfe, L., & Zee, P. (2010) Aerobic exercise improves self-reported sleep and quality of life in older adults with insomnia. Sleep Medicine, 11(9), 934-940. DOI: 10.1016/j.sleep.2010.04.014
by Alvin Lin in United Academics
Snap! Ouch! That’s from my head doing a double take. All these years, I thought the calcium vs heart disease thing was a conspiracy arranged by one researcher and publication. However, 3 months ago, I stumbled upon some corroborating studies by other researchers in other journals. Even the US Preventive Services Task Force recently came out against low dose calcium (less than 1,000mg/d) in post-menopausal women because they could not find conclusive evidence of benefit in the face of a ........ Read more »
Bolland, M., Grey, A., Avenell, A., Gamble, G., & Reid, I. (2011) Calcium supplements with or without vitamin D and risk of cardiovascular events: reanalysis of the Women's Health Initiative limited access dataset and meta-analysis. BMJ, 342(apr19 1). DOI: 10.1136/bmj.d2040
Langsetmo, L., Berger, C., Kreiger, N., Kovacs, C., Hanley, D., Jamal, S., Whiting, S., Genest, J., Morin, S., Hodsman, A.... (2013) Calcium and Vitamin D Intake and Mortality: Results from the Canadian Multicentre Osteoporosis Study (CaMos). Journal of Clinical Endocrinology . DOI: 10.1210/jc.2013-1516
by Andrew Porterfield in United Academics
The Irish Famine (or “Great Potato Famine” if you live outside the Emerald Isle) killed one million people and forced another million to leave the country between 1845 and 1852. It was caused by a blight on the country’s main food stock—the Irish “Lumper” potato. Now, researchers have identified the genome of the blight behind the famine.... Read more »
Kentaro Yoshida, Verena J. Schuenemann, Liliana M. Cano, Marina Pais, Bagdevi Mishra, Rahul Sharma, Christa Lanz, Frank N. Martin, Sophien Kamoun, Johannes Krause.... (2013) The rise and fall of the Phytophthora infestans lineage that triggered the Irish potato famine. eLife. arXiv: 1305.4206v1
by Fungi in Bath Fungal Research
--> The mycobiome is starting to get a little traction!When will we know the weight of the fungi on and in our bodies? The human microbiota has been recognized as hugely important in the last few years, but that has almost entirely focused on bacteria. I’ve been interested in the mycobiome of the human built environment for a while, and I certainly haven’t been alone. People tend to think of fungi as a problem in buildings, on or in plants, and in the outside air. However, there is ........ Read more »
Iliev, I., Funari, V., Taylor, K., Nguyen, Q., Reyes, C., Strom, S., Brown, J., Becker, C., Fleshner, P., Dubinsky, M.... (2012) Interactions Between Commensal Fungi and the C-Type Lectin Receptor Dectin-1 Influence Colitis. Science, 336(6086), 1314-1317. DOI: 10.1126/science.1221789
Findley, K., Oh, J., Yang, J., Conlan, S., Deming, C., Meyer, J., Schoenfeld, D., Nomicos, E., Park, M., Becker, J.... (2013) Topographic diversity of fungal and bacterial communities in human skin. Nature. DOI: 10.1038/nature12171
Huffnagle, G., & Noverr, M. (2013) The emerging world of the fungal microbiome. Trends in Microbiology. DOI: 10.1016/j.tim.2013.04.002
by Fungi in Bath Fungal Research
Picking up on my infatuation with all things Hsp, today more on the effects of two of the large Hsps on Candida albicans biofilm formation and virulence in mice and worms.Ssa1, a member of the Hsp70 family, is traditionally implicated in protein folding and entwining. Following heat shock, Ssa1 expression increases, which is a hallmark of heat shock proteins. Recently, Ssa1’s role in Candida albicans’ virulence has been extensively characterized. A series of experiments involving C. al........ Read more »
Fiori, A., Kucharikova, S., Govaert, G., Cammue, B., Thevissen, K., & Van Dijck, P. (2012) The Heat-Induced Molecular Disaggregase Hsp104 of Candida albicans Plays a Role in Biofilm Formation and Pathogenicity in a Worm Infection Model. Eukaryotic Cell, 11(8), 1012-1020. DOI: 10.1128/EC.00147-12
Sun JN, Solis NV, Phan QT, Bajwa JS, Kashleva H, Thompson A, Liu Y, Dongari-Bagtzoglou A, Edgerton M, & Filler SG. (2010) Host cell invasion and virulence mediated by Candida albicans Ssa1. PLoS pathogens, 6(11). PMID: 21085601
by Rebecca Kreston in BODY HORRORS
Drinking pruno is a risky endeavor, both in terms of its offense to culinary sensibilities and to one's health. However, turned stomachs are not the only hazard here; you may add a desire to avoid botulism to your list of reasons to shy away from you'r mates latest batch of prison hooch. The soil-dwelling bacterium Clostridium botulinum can contaminate fruits and veggies, and, in warm, oxygen-deprived conditions, produces the neuroparalytic toxin botulinum. Even more wholesome DIY ende........ Read more »
Centers for Disease Control and Prevention (CDC). (2013) Notes from the field: botulism from drinking prison-made illicit alcohol - Arizona, 2012. MMWR. Morbidity and mortality weekly report, 62(5), 88. PMID: 23388552
by Pieter Carriere in United Academics
Depression or Major Depressive Disorder (MDD) has multiple genetic and environmental causes. Genetic factors are hard to find and the discovered factors usually are also associated with other mood disorders. Furthermore, twin studies reveal that genetics can predict 37% of the depressions, which is a much lower heritability than in bipolar disorder, a comparable mood disorder (reviewed in Belmaker et al., 2008). ... Read more »
Papakostas, G., Shelton, R., Kinrys, G., Henry, M., Bakow, B., Lipkin, S., Pi, B., Thurmond, L., & Bilello, J. (2011) Assessment of a multi-assay, serum-based biological diagnostic test for major depressive disorder: a Pilot and Replication Study. Molecular Psychiatry, 18(3), 332-339. DOI: 10.1038/mp.2011.166
Pariante, C., & Lightman, S. (2008) The HPA axis in major depression: classical theories and new developments. Trends in Neurosciences, 31(9), 464-468. DOI: 10.1016/j.tins.2008.06.006
Raison, C. (2012) A Randomized Controlled Trial of the Tumor Necrosis Factor Antagonist Infliximab for Treatment-Resistant DepressionThe Role of Baseline Inflammatory BiomarkersInfliximab for Treatment-Resistant Depression. Archives of General Psychiatry, 1. DOI: 10.1001/2013.jamapsychiatry.4
Nibuya M, Morinobu S, & Duman RS. (1995) Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments. The Journal of neuroscience : the official journal of the Society for Neuroscience, 15(11), 7539-47. PMID: 7472505
by Andrew Porterfield in United Academics
classical music and intense sensory exercises produced improvements in autism symptoms in children after just six months, scientists have found.... Read more »
Woo, C., & Leon, M. (2013) Environmental Enrichment as an Effective Treatment for Autism: A Randomized Controlled Trial. Behavioral Neuroscience. DOI: 10.1037/a0033010
by Paul Whiteley in Questioning Answers
An episode of the BBC program Horizon on 'Big Data' recently caught my attention. The content was a fascinating insight into how we are living in a data-rich age and how trawling/mining/dredging such data has the ability to advance medicine, predict crime and even make someone a few quid/dollars/euros on the stock market.Gone (data) fishing @ Wikipedia I'm a big believer in big data. In particular how, with the right sources, technology, techniques and people, big data might be able t........ Read more »
Mizejewski GJ, Lindau-Shepard B, & Pass KA. (2013) Newborn screening for autism: in search of candidate biomarkers. Biomarkers in medicine, 7(2), 247-60. PMID: 23547820
by Dirk Hanson in Addiction Inbox
Teasing out the insulin effect.
On the face of it, the study seems to come out of left field: A group of researchers claimed that marijuana smokers showed 16 per cent lower fasting insulin levels than non-smokers. The study, called “The Impact of Marijuana Use on Glucose, Insulin, and Insulin Resistance among US Adults,” is in press for The American Journal of Medicine. The authors are a diverse group of medical researchers from Harvard, Beth Israel Deaconess Medical Center, and t........ Read more »
Penner Elizabeth A., Buettner Hannah, & Mittleman Murray A. (2013) The Impact of Marijuana Use on Glucose, Insulin, and Insulin Resistance among US Adults. The American Journal of Medicine. DOI: 10.1016/j.amjmed.2013.03.002
Recently we attended the Medical Library Association conference (#MLAnet13). Librarians are working so hard to wrangle information into usable forms, and to generate new connections among data types to reveal new information and leads for further studies. I ♥ librarians. In one of the sessions I attended on Medical Informatics, I heard several great talks. One [...]... Read more »
Rabinowitz, P., Scotch, M., & Conti, L. (2010) Animals as Sentinels: Using Comparative Medicine To Move Beyond the Laboratory. ILAR Journal, 51(3), 262-267. DOI: 10.1093/ilar.51.3.262
Rabinowitz, P., Gordon, Z., Holmes, R., Taylor, B., Wilcox, M., Chudnov, D., Nadkarni, P., & Dein, F. (2005) Animals as Sentinels of Human Environmental Health Hazards: An Evidence-Based Analysis. EcoHealth, 2(1), 26-37. DOI: 10.1007/s10393-004-0151-1
Rabinowitz, P., Cullen, M., & Lake, H. (1999) Wildlife as sentinels for human health hazards: a review of study designs. Journal of Environmental Medicine, 1(4), 217-223. DOI: 10.1002/jem.33
by AB Kirk in Stff Competition
CrossFit Regionals Competitions s are almost here. Athletes should arrive well rested and hopefully injury free. CrossFit Regionals competitions are very intense. Athletes will have to complete several WODs aThe post CrossFit Regionals Competitions: Ice Baths and Deep Massage. Do they help? appeared first on WODMasters Stiff Competition.... Read more »
Delextrat A, Calleja-González J, Hippocrate A, & Clarke ND. (2013) Effects of sports massage and intermittent cold-water immersion on recovery from matches by basketball players. Journal of sports sciences, 31(1), 11-9. PMID: 22935028
by Tony Ingram in BBoy Science
There is actually no such thing as a "pain sensor" or "pain fiber" - but there is the fascinating system of nociception! An important concept in understanding pain.... Read more »
Basbaum AI, Bautista DM, Scherrer G, & Julius D. (2009) Cellular and molecular mechanisms of pain. Cell, 139(2), 267-84. PMID: 19837031
by AB Kirk in Stff Competition
CrossFit Woman, Depression, Female Hormones and Anti-Depressants A CrossFit woman usually take good care of herself. We do CrossFit. We lift weights. Eat well. Get lots of exercise. All theseThe post CrossFit Woman: How Hormone Replacement Therapy May Protect You From Depression. appeared first on WODMasters Stiff Competition.... Read more »
Michopoulos V, Berga SL, & Wilson ME. (2011) Estradiol and progesterone modify the effects of the serotonin reuptake transporter polymorphism on serotonergic responsivity to citalopram. Experimental and clinical psychopharmacology, 19(6), 401-8. PMID: 21843009
by Anouk Vleugels in United Academics
Last February, Dr. Sam Parnia, an intensive care physician who has been researching near-death experiences for the past 15 years, published his new book ‘Erasing death: The Science That is Rewriting the Boundaries Between Life and Death’. Following the release of that book, Dr. Parnia was interviewed on National Public Radio in the US. It wasn’t so much this interview that sparked my interest, as much as the comments that followed. “It’s hard to believe that this gu........ Read more »
van Lommel P, van Wees R, Meyers V, & Elfferich I. (2001) Near-death experience in survivors of cardiac arrest: a prospective study in the Netherlands. Lancet, 358(9298), 2039-45. PMID: 11755611
by Vivek Misra in Beautiful Mind
tumblr: bellapaige88On average, 9.5/1000 population has epilepsy in Low and Middle Income Countries (LAMIC). A research which has resulted in the global campaign against epilepsy has shown, the gap between treatment need and the treatment provision worldwide is approximately 70% [1]. This large ‘treatment gap’, i.e., lack of appropriate treatment for a large number of patients with epilepsy, due to a number of causes including inability to identify cases, inability to deliver adequate treatm........ Read more »
Mbuba CK, Ngugi AK, Newton CR, & Carter JA. (2008) The epilepsy treatment gap in developing countries: a systematic review of the magnitude, causes, and intervention strategies. Epilepsia, 49(9), 1491-503. PMID: 18557778
Pal, D., Das, T., & Sengupta, S. (2000) Case-control and qualitative study of attrition in a community epilepsy programme in rural India. Seizure, 9(2), 119-123. DOI: 10.1053/seiz.1999.0357
Mani KS, Rangan G, Srinivas HV, Srindharan VS, & Subbakrishna DK. (2001) Epilepsy control with phenobarbital or phenytoin in rural south India: the Yelandur study. Lancet, 357(9265), 1316-20. PMID: 11343735
Wang WZ, Wu JZ, Wang DS, Dai XY, Yang B, Wang TP, Yuan CL, Scott RA, Prilipko LL, de Boer HM.... (2003) The prevalence and treatment gap in epilepsy in China: an ILAE/IBE/WHO study. Neurology, 60(9), 1544-5. PMID: 12743252
by Shawn Radcliffe in Branáin
Staying hydrated is good advice for men who’ve had kidney stones before, but sugar-sweetened sodas and fruit punch may not be the best choice of fluids.... Read more »
Ferraro, P., Taylor, E., Gambaro, G., & Curhan, G. (2013) Soda and Other Beverages and the Risk of Kidney Stones. Clinical Journal of the American Society of Nephrology. DOI: 10.2215/CJN.11661112
by Usman Paracha in SayPeople
Main Points:
Researchers have found that the cancer patients in America are more than two times more likely to go bankrupt than the healthy people. I think this is the case not only in America but everywhere in the world.
Published in:
Health Affairs
Study Further:
Researchers collected data in Washington State from about 400,000 adults and found that the patients of cancer have more chances of bankruptcy, i.e. 2.65 times more chances, even if they have the health insurance as the........ Read more »
Ramsey, S., Blough, D., Kirchhoff, A., Kreizenbeck, K., Fedorenko, C., Snell, K., Newcomb, P., Hollingworth, W., & Overstreet, K. (2013) Washington State Cancer Patients Found To Be At Greater Risk For Bankruptcy Than People Without A Cancer Diagnosis. Health Affairs. DOI: 10.1377/hlthaff.2012.1263
by William Yates, M.D. in Brain Posts
The U.S. Centers for Disease Control has published a comprehensive summary of the epidemiology of childhood brain disorders in the most recent Morbidity and Mortality Weekly Report.This report produced some sensationalized headlines that up to 20% of children suffer from a mental disorder. However, I was more interested in looking at the prevalence estimates for some of the individual disorders from the report.The report collates data collected from a variety of surveys and data sets inclu........ Read more »
Perou R, Bitsko RH, Blumberg SJ, Pastor P, Ghandour RM, Gfroerer JC, Hedden SL, Crosby AE, Visser SN, Schieve LA.... (2013) Mental health surveillance among children - United States, 2005-2011. Morbidity and mortality weekly report. Surveillance summaries (Washington, D.C. : 2002), 62(2), 1-35. PMID: 23677130
by AB Kirk in Stff Competition
CrossFit Nutrition: Cell Health and Telomeres. CrossFit Nutrition: you can only be as healthy as your cells. One marker of cell health is telomere length. Telomeres cap the ends ofThe post CrossFit Nutrition: Saturated Fat and Cell Health appeared first on WODMasters Stiff Competition.... Read more »
Song Y, You NC, Song Y, Kang MK, Hou L, Wallace R, Eaton CB, Tinker LF, & Liu S. (2013) Intake of Small-to-Medium-Chain Saturated Fatty Acids Is Associated with Peripheral Leukocyte Telomere Length in Postmenopausal Women. The Journal of nutrition. PMID: 23616516
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