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  • August 1, 2016
  • 07:36 PM
  • 80 views

This Month in Blastocystis Research - Interactive Edition

by Christen Rune Stensvold in Blastocystis Parasite Blog

What are your thoughts on Blastocystis carriage and age? Please comment!... Read more »

  • July 14, 2016
  • 01:27 PM
  • 214 views

Weird stuff found in recreational drugs: Cocaine edition

by Rosin Cerate in Rosin Cerate

This is the fifth and final post in a series on strange substances accidentally or intentionally added to street drugs. When you're done here, check out the posts on alcohol, meth, opioids, and pot/LSD.If a drug is being sold illegally, chances are its sellers have added crap to it in order to make more money. Cocaine is no exception to this deception. Substances added to nose candy because they resemble the drug but otherwise don't mimic or influence its effects include talc powder, flour, corn........ Read more »

  • July 13, 2016
  • 10:57 AM
  • 177 views

The Genetic Architecture of Complex Disease

by Daniel Koboldt in Massgenomics

It’s no secret that while genome-wide association studies (GWAS) have implicated thousands of genetic loci in human phenotypes, the variants uncovered collectively explain only a fraction of the observed variance between individuals. The reasons for this “missing heritability” are a subject of vigorous debate in the scientific community. One possible explanation is that rare (low-frequency) variants […]... Read more »

Fuchsberger C, Flannick J, Teslovich TM, Mahajan A, Agarwala V, Gaulton KJ, Ma C, Fontanillas P, Moutsianas L, McCarthy DJ.... (2016) The genetic architecture of type 2 diabetes. Nature. PMID: 27398621  

  • June 23, 2016
  • 08:55 AM
  • 44 views

Weird stuff found in recreational drugs: Pot/LSD edition

by Rosin Cerate in Rosin Cerate

This is the fourth post in a series on strange substances accidentally or intentionally added to street drugs. When you're done here, check out the posts on alcohol, meth, opioids, and cocaine.In the autumn of 2007, hospitals near Leipzig, Germany admitted 29 people after they inadvertently smoked weed contaminated with lead. Yep, some dealer or grower decided it was a good idea to drop a bunch of small lead particles into the marijuana they were selling, presumably to increase its weight (lead ........ Read more »

Busse F, Omidi L, Timper K, Leichtle A, Windgassen M, Kluge E, & Stumvoll M. (2008) Lead poisoning due to adulterated marijuana. The New England Journal of Medicine, 358(15), 1641-1642. PMID: 18403778  

  • June 21, 2016
  • 08:17 AM
  • 163 views

Weird stuff found in recreational drugs: Opioid edition

by Rosin Cerate in Rosin Cerate

This is the third post in a series on strange substances accidentally or intentionally added to street drugs. When you're done here, check out the posts on alcohol and meth.Opioids are drugs that affect the human body by binding to a group of related proteins conveniently known as opioid receptors. By connecting to these receptors in a certain manner, they convince receptor-bearing cells in the brain, spinal cord, and intestine to do useful things like reduce the sensation of pain (while making ........ Read more »

Brett M, Hallas G, & Mpamugo O. (2004) Wound botulism in the UK and Ireland. . Journal of Medical Microbiology, 53(6), 555-561. DOI: 10.1099/jmm.0.05379-0  

  • June 15, 2016
  • 10:18 AM
  • 217 views

Weird stuff found in recreational drugs: Meth edition

by Rosin Cerate in Rosin Cerate

As Breaking Bad has taught us, the clandestine manufacture of methamphetamine is a very dangerous undertaking. It involves the use of many harmful substances, which depending on the synthesis method include highly corrosive acids and bases, cancer-causing benzene, brain-damaging mercury and lead, jaw-wrecking phosphorus, and blood-breaking sodium cyanide. Blending these various substances together can produce noxious fumes, making gas masks and chemical suits a necessity if you want to avoid get........ Read more »

Cole C, Jones L, McVeigh J, Kicman A, Syed Q, & Bellis M. (2011) Adulterants in illicit drugs: A review of empirical evidence. Drug Testing and Analysis, 3(2), 89-96. PMID: 21322119  

  • June 13, 2016
  • 08:30 PM
  • 218 views

This Month in Blastocystis Research (MAY 2016)

by Christen Rune Stensvold in Blastocystis Parasite Blog

The May entry of "This Month in Blastocystis Research" focusses especially on the increasing interest in Blastocystis in a gut microbiota context. ... Read more »

Andersen LO, Bonde I, Nielsen HB, & Stensvold CR. (2015) A retrospective metagenomics approach to studying Blastocystis. FEMS microbiology ecology, 91(7). PMID: 26130823  

Stensvold CR, & Clark CG. (2016) Current status of Blastocystis: A personal view. Parasitology international. PMID: 27247124  

O'Brien Andersen L, Karim AB, Roager HM, Vigsnæs LK, Krogfelt KA, Licht TR, & Stensvold CR. (2016) Associations between common intestinal parasites and bacteria in humans as revealed by qPCR. European journal of clinical microbiology . PMID: 27230509  

Ramírez JD, Sánchez A, Hernández C, Flórez C, Bernal MC, Giraldo JC, Reyes P, López MC, García L, Cooper PJ.... (2016) Geographic distribution of human Blastocystis subtypes in South America. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, 32-5. PMID: 27034056  

  • June 12, 2016
  • 10:35 PM
  • 264 views

Seeing Through the Skin

by Aurametrix team in Olfactics and Diagnostics

​Human skin emits light (albeit the glow is extremely weak) and a wide variety of small molecules that may be sometimes "sniffed" by dogs or even other humans. These chemicals tell a story about our health and wellness, things we eat and drink, touch and breathe. Mosquitoes use such emissions to assess our "attractiveness" from indicators such as Indoles (unpleasantly smelling but healthy "inner soil" biomarker) or carbon dioxide (amount of which correlates with the size of the person........ Read more »

Gao W, Emaminejad S, Nyein HY, Challa S, Chen K, Peck A, Fahad HM, Ota H, Shiraki H, Kiriya D.... (2016) Fully integrated wearable sensor arrays for multiplexed in situ perspiration analysis. Nature, 529(7587), 509-14. PMID: 26819044  

Yokota T, Zalar P, Kaltenbrunner M, Jinno H, Matsuhisa N, Kitanosako H, Tachibana Y, Yukita W, Koizumi M, & Someya T. (2016) Ultraflexible organic photonic skin. Science advances, 2(4). PMID: 27152354  

  • June 8, 2016
  • 07:22 AM
  • 245 views

Weird stuff found in recreational drugs: Alcohol edition

by Rosin Cerate in Rosin Cerate

Today's post is the first in a series I'm going to write about extra ingredients found in illicit recreational drugs. One of the major issues with street drugs is their manufacture and distribution is often poorly regulated. This means they can accidentally become contaminated with all sorts of toxic substances during production. Additionally, a wide range of chemical compounds, some of them harmful, may be intentionally added to dilute a drug (like a bar watering down their drinks to make more ........ Read more »

Holstege CP, Ferguson JD, Wolf CE, Baer AB, & Poklis A. (2004) Analysis of moonshine for contaminants. Journal of Toxicology. Clinical Toxicology, 42(5), 597-601. PMID: 15462151  

  • May 17, 2016
  • 02:35 PM
  • 224 views

Nurses Frequently Attending Church Live Longer

by William Yates, M.D. in Brain Posts

The Harvard-based Nurses' Health Study has been a remarkably productive longitudinal health study.My wife has been a subject in this study and frequently completes interval questionnaires regarding her health status.A recent publication looked at the relationship between religious service attendance and mortality in the Nurses's Health Study cohort.This manuscript tried to provide a more valid look at the relationship between religiosity/spirituality and health. Previous studies have found a lin........ Read more »

Li, S., Stampfer, M., Williams, D., & VanderWeele, T. (2016) Association of Religious Service Attendance With Mortality Among Women. JAMA Internal Medicine. DOI: 10.1001/jamainternmed.2016.1615  

  • May 16, 2016
  • 03:34 PM
  • 292 views

Novel Borrelia Species Causes Lyme Disease with High Spirochetemia

by Pranab Chatterjee in Zoonoticus

In a recent paper in the Lancet Infectious Diseases, Pritt et al have identified a new genospecies of Borrelia which is attributed to have caused several cases of Lyme disease, marked by a high degree of spirochetemia. In their research article abstract, they state: Methods At the Mayo clinic, from 2003 to 2014, we tested […]... Read more »

  • May 13, 2016
  • 02:25 AM
  • 244 views

Friday the 13th

by Aurametrix team in Environmental health

Our health depends on a multitude of environmental factors, day in and day out. And today is a special day - Friday the 13th. How should you feel on this day? Friday the 13th is one of the most feared dates, associated with bad luck in the West. And it is taken cautiously even in cultures that do not fear the 13th - for example, among Chinese mothers avoiding delivering their babies on the 13th. But science says that those born on the 13th and even those born on Friday the 13th are not in ........ Read more »

Fidrmuc, J., & Tena, J. (2015) Friday the 13th: The Empirics of Bad Luck. Kyklos, 68(3), 317-334. DOI: 10.1111/kykl.12085  

Lucey, B. (2002) Friday the 13th and the Philosophical Basis of Financial Economics. SSRN Electronic Journal. DOI: 10.2139/ssrn.962697  

Chung, R., Darrat, A., & Li, B. (2014) Superstitions and stock trading: some new evidence. Journal of the Asia Pacific Economy, 19(4), 527-538. DOI: 10.1080/13547860.2014.920589  

Stone, A., Schneider, S., & Harter, J. (2012) Day-of-week mood patterns in the United States: On the existence of ‘Blue Monday’, ‘Thank God it's Friday’ and weekend effects. The Journal of Positive Psychology, 7(4), 306-314. DOI: 10.1080/17439760.2012.691980  

Almond D, Chee CP, Sviatschi MM, & Zhong N. (2015) Auspicious birth dates among Chinese in California. Economics and human biology, 153-9. PMID: 26160600  

  • May 11, 2016
  • 01:00 PM
  • 134 views

How to Solve Homicide Crimes

by William Yates, M.D. in Brain Posts

Homicide rates in the U.S. represent a significant public health challenge. Homicide is a top ten leading cause of death in many groups in the U.S.One method to reduce homicide rates is to quickly identify and arrest individuals who have committed homicide. This is due to the fact that individuals committing homicide have a high rate of future homicide.A recent study from Michigan State University and Indiana University examined characteristics of U.S. police departments that have high rates of ........ Read more »

Carter, D., & Carter, J. (2015) Effective Police Homicide Investigations: Evidence From Seven Cities With High Clearance Rates. Homicide Studies, 20(2), 150-176. DOI: 10.1177/1088767915576996  

  • May 5, 2016
  • 10:23 AM
  • 80 views

Left Kidney Donation Preference

by Cristy at Living Donor 101 in Living Donors Are People Too

During living kidney donation, the left kidney is most often taken because the right kidney rests behind the liver. In simple terms, it’s easier to access the left kidney. But it also appears that the left kidney has a longer renal vessel than the right (an important consideration that is rarely, if ever, mentioned during …
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The post Left Kidney Donation Preference appeared first on Living Donors Are People Too.
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Özdemir-van Brunschot, D., van Laarhoven, C., van der Jagt, M., Hoitsma, A., & Warlé, M. (2015) Is the Reluctance for the Implantation of Right Donor Kidneys Justified?. World Journal of Surgery, 40(2), 471-478. DOI: 10.1007/s00268-015-3232-0  

  • May 3, 2016
  • 12:00 PM
  • 138 views

"The Biggest Loser": Long-term Effects

by William Yates, M.D. in Brain Posts

Yesterday I posted a link to a New York Times article that posted a summary outcome in fourteen participants in TV's "The Biggest Loser" show.The study found a trend towards post-show weight gain for 13/14 of the participants.Four participants actually gained so much weight that after six years they weighed more than before participating in the show.A key finding from the study was this weight gain could be explained by a metabolic response resulting in up to 800 calories less burned daily ........ Read more »

Fothergill, E., Guo, J., Howard, L., Kerns, J., Knuth, N., Brychta, R., Chen, K., Skarulis, M., Walter, M., Walter, P.... (2016) Persistent metabolic adaptation 6 years after “The Biggest Loser” competition. Obesity. DOI: 10.1002/oby.21538  

  • May 2, 2016
  • 01:10 PM
  • 70 views

Kidney Donors Suffer More Pain

by Cristy at Living Donor 101 in Living Donors Are People Too

The authors compared 30 living kidney donors with 30 other individuals who underwent a nephrectomy (kidney removal) because of a tumor. They found that living kidney donors experienced more pain than the comparison group, and they asked for (and were given) more pain medications. Wang, J., Fu, Y., Yuan, T., & Wang, N. (2015). Comparison …
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The post Kidney Donors Suffer More Pain appeared first on Living Donors Are People Too.
... Read more »

  • April 28, 2016
  • 11:19 AM
  • 69 views

Psychiatric Complications in Living Liver Donors

by Cristy at Living Donor 101 in Living Donors Are People Too

The authors studied 142 donors who underwent live-donor liver transplantation at Nagoya University Hospital between April 2004 and July 2014. None of the living donors had pre-existing psychological complaints prior to donation.   4.2% developed psychiatric complaints after donation, including major depressive disorder, panic disorder, conversion disorder, and substance use disorder. (my emphasis) “all donors received …
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The post Psychiatric Complication........ Read more »

Kimura, H., Onishi, Y., Sunada, S., Kishi, S., Suzuki, N., Tsuboi, C., Yamaguchi, N., Imai, H., Kamei, H., Fujisiro, H.... (2015) Postoperative Psychiatric Complications in Living Liver Donors. Transplantation Proceedings, 47(6), 1860-1865. DOI: 10.1016/j.transproceed.2015.06.021  

  • April 26, 2016
  • 07:02 AM
  • 296 views

Gently frying your eyeballs at work

by Rosin Cerate in Rosin Cerate

When I was a kid, I got thwacked in the face with a golf club. It was totally my fault. I was goofing around with my cousins (as one does) and failed to notice one of them winding up for a swing. Ended up with four stitches, the first one just half an inch from my left eye.... Read more »

  • April 25, 2016
  • 11:18 AM
  • 221 views

Liver Regeneration in Living Donors

by Cristy at Living Donor 101 in Living Donors Are People Too

The authors examined the liver function and liver volume of 91 right liver lobe donors. Within a year of donating, 96% had regained full liver function but only 85% had full pre-donation liver volume.   Unfortunately, these results say nothing about the long term risk of scarring (cirrhosis) or otherwise.   Duclos J, Bhangui P, …
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The post Liver Regeneration in Living Donors appeared first on Living Donors Are People Too.
... Read more »

Duclos J, Bhangui P, Salloum C, Andreani P, Saliba F, Ichai P, Elmaleh A, Castaing D, & Azoulay D. (2016) Ad Integrum Functional and Volumetric Recovery in Right Lobe Living Donors: Is It Really Complete 1 Year After Donor Hepatectomy?. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 16(1), 143-56. PMID: 26280997  

  • April 23, 2016
  • 12:41 PM
  • 180 views

Does E. ewingii Cause More Cases of Ehrlichiosis Than Previously Thought?

by Pranab Chatterjee in Zoonoticus

This figure shows the incidence of ehrlichicosis cases by state in 2010 per million persons. Ehrlichiosis was not notifiable in Alaska, Colorado, the District of Columbia, Hawaii, Idaho, Iowa, Nevada, New Mexico, North Dakota or Montana. The incidence rate was zero for Arizona, Connecticut, Indiana, Massachusetts, Oregon, South Dakota, Utah, Vermont, Washington, and Wyoming. Incidence […]... Read more »

Harris, R., Couturier, B., Sample, S., Coulter, K., Casey, K., & Schlaberg, R. (2016) Expanded Geographic Distribution and Clinical Characteristics of Infections, United States . Emerging Infectious Diseases, 22(5), 862-865. DOI: 10.3201/eid2205.152009  

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