All posts; Tags Include "Health Policy"
- September 8, 2016
- 09:16 AM
- 292 views
CRISPR on my plate, and some GMO’s on the side
by gdw in FictionalFieldwork
A CRISPR recipe Less than a month ago, the world’s first official CRISPR/Cas9 meal was served. CRISPR/Cas9 is a fairly new technology to edit genomes, and cut and paste genes at will. Well, it’s not exactly that new. It’s actually been around for a long time. CRISPR, or *humhum* Clustered regularly interspaced short palindromic repeats […]... Read more »
Snell C, Bernheim A, Bergé JB, Kuntz M, Pascal G, Paris A, & Ricroch AE. (2012) Assessment of the health impact of GM plant diets in long-term and multigenerational animal feeding trials: a literature review. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(3-4), 1134-48. PMID: 22155268
Panchin AY, & Tuzhikov AI. (2016) Published GMO studies find no evidence of harm when corrected for multiple comparisons. Critical reviews in biotechnology, 1-5. PMID: 26767435
- August 25, 2016
- 09:40 AM
- 351 views
How to rebuild a brain
by gdw in FictionalFieldwork
After the stroke The human brain is complicated. Very complicated. And like any piece of complex machinery that relies on the smooth functioning of many components, it’s not immune to malfunction. When a part of the brain doesn’t get proper nutrition through a nice and smooth blood flow, things go awry and a stroke occurs. […]... Read more »
Chowdhury R, Stevens S, Gorman D, Pan A, Warnakula S, Chowdhury S, Ward H, Johnson L, Crowe F, Hu FB.... (2012) Association between fish consumption, long chain omega 3 fatty acids, and risk of cerebrovascular disease: systematic review and meta-analysis. BMJ (Clinical research ed.). PMID: 23112118
Hurst K, Lee R, Sideso E, Giles M, & Handa A. (2016) Delays in the presentation to stroke services of patients with transient ischaemic attack and minor stroke. The British journal of surgery. PMID: 27529453
Mayurasakorn K, Niatsetskaya ZV, Sosunov SA, Williams JJ, Zirpoli H, Vlasakov I, Deckelbaum RJ, & Ten VS. (2016) DHA but Not EPA Emulsions Preserve Neurological and Mitochondrial Function after Brain Hypoxia-Ischemia in Neonatal Mice. PloS one, 11(8). PMID: 27513579
Wang Y, Zhao Z, Rege SV, Wang M, Si G, Zhou Y, Wang S, Griffin JH, Goldman SA, & Zlokovic BV. (2016) 3K3A-activated protein C stimulates postischemic neuronal repair by human neural stem cells in mice. Nature medicine. PMID: 27548576
- August 3, 2016
- 09:13 AM
- 406 views
Do we need a doping Olympics? The ethics of doping in sports
by gdw in FictionalFieldwork
There is only her and the track. The people standing on her left and right do not matter now. She has only one adversary: time. In her head she plays how the future might…will unfold. Forty seven strides. That’s all she needs. All things on the periphery disappear. Her world, her universe becomes a single […]... Read more »
Savulescu J, Foddy B, & Clayton M. (2004) Why we should allow performance enhancing drugs in sport. British journal of sports medicine, 38(6), 666-70. PMID: 15562155
Gaviglio CM, Osborne M, Kelly VG, Kilduff LP, & Cook CJ. (2015) Salivary testosterone and cortisol responses to four different rugby training exercise protocols. European journal of sport science, 15(6), 497-504. PMID: 25743223
Smith AC, & Stewart B. (2015) Why the war on drugs in sport will never be won. Harm reduction journal, 53. PMID: 26556215
Park HY, Hwang H, Park J, Lee S, & Lim K. (2016) The effects of altitude/hypoxic training on oxygen delivery capacity of the blood and aerobic exercise capacity in elite athletes - a meta-analysis. Journal of exercise nutrition , 20(1), 15-22. PMID: 27298808
- May 16, 2016
- 03:34 PM
- 531 views
Novel Borrelia Species Causes Lyme Disease with High Spirochetemia
by Pranab Chatterjee in Zoonoticus
In a recent paper in the Lancet Infectious Diseases, Pritt et al have identified a new genospecies of Borrelia which is attributed to have caused several cases of Lyme disease, marked by a high degree of spirochetemia. In their research article abstract, they state: Methods At the Mayo clinic, from 2003 to 2014, we tested […]... Read more »
Pritt BS, Mead PS, Johnson DK, Neitzel DF, Respicio-Kingry LB, Davis JP, Schiffman E, Sloan LM, Schriefer ME, Replogle AJ.... (2016) Identification of a novel pathogenic Borrelia species causing Lyme borreliosis with unusually high spirochaetaemia: a descriptive study. The Lancet. Infectious diseases. PMID: 26856777
- April 23, 2016
- 12:41 PM
- 340 views
Does E. ewingii Cause More Cases of Ehrlichiosis Than Previously Thought?
by Pranab Chatterjee in Zoonoticus
This figure shows the incidence of ehrlichicosis cases by state in 2010 per million persons. Ehrlichiosis was not notifiable in Alaska, Colorado, the District of Columbia, Hawaii, Idaho, Iowa, Nevada, New Mexico, North Dakota or Montana. The incidence rate was zero for Arizona, Connecticut, Indiana, Massachusetts, Oregon, South Dakota, Utah, Vermont, Washington, and Wyoming. Incidence […]... Read more »
Harris, R., Couturier, B., Sample, S., Coulter, K., Casey, K., & Schlaberg, R. (2016) Expanded Geographic Distribution and Clinical Characteristics of Infections, United States . Emerging Infectious Diseases, 22(5), 862-865. DOI: 10.3201/eid2205.152009
- April 6, 2016
- 12:02 PM
- 406 views
World Serology Bank: Key to a Better Understanding of Infectious Disease Dynamics?
by Pranab Chatterjee in Zoonoticus
An article published in The Lancet today has highlighted the possibility of establishing a World Serology Bank to better understand the dynamics of infectious disease dynamics, especially in an era where vaccinations against infectious diseases is becoming more and more prevalent. With rapid advance in diagnostic technologies, there has been impressive progress in what used […]... Read more »
Metcalf, C., Farrar, J., Cutts, F., Basta, N., Graham, A., Lessler, J., Ferguson, N., Burke, D., & Grenfell, B. (2016) Use of serological surveys to generate key insights into the changing global landscape of infectious disease. The Lancet. DOI: 10.1016/S0140-6736(16)30164-7
- February 28, 2016
- 08:35 AM
- 834 views
Week 8 In Review: Open-Access Science | 22 to 28 Feb
by TakFurTheKaffe in Tak Fur The Kaffe
Sea level rose faster in the 20th century than in any other century of the last 3,000 years, new methods for estimating future sea level rise and heat waves, consumers to blame for their carbon footprint, and new virtual forests predict future impacts of climate change. Here are five of the latest scientific studies published open-access this week.... Read more »
Kopp, R., Kemp, A., Bittermann, K., Horton, B., Donnelly, J., Gehrels, W., Hay, C., Mitrovica, J., Morrow, E., & Rahmstorf, S. (2016) Temperature-driven global sea-level variability in the Common Era. Proceedings of the National Academy of Sciences, 201517056. DOI: 10.1073/pnas.1517056113
Mengel, M., Levermann, A., Frieler, K., Robinson, A., Marzeion, B., & Winkelmann, R. (2016) Future sea level rise constrained by observations and long-term commitment. Proceedings of the National Academy of Sciences, 201500515. DOI: 10.1073/pnas.1500515113
Leary, E., Young, L., DuClos, C., & Jordan, M. (2015) Identifying Heat Waves in Florida: Considerations of Missing Weather Data. PLOS ONE, 10(11). DOI: 10.1371/journal.pone.0143471
Ivanova, D., Stadler, K., Steen-Olsen, K., Wood, R., Vita, G., Tukker, A., & Hertwich, E. (2015) Environmental Impact Assessment of Household Consumption. Journal of Industrial Ecology. DOI: 10.1111/jiec.12371
Liénard, J., & Strigul, N. (2016) An individual-based forest model links canopy dynamics and shade tolerances along a soil moisture gradient. Royal Society Open Science, 3(2), 150589. DOI: 10.1098/rsos.150589
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- February 9, 2016
- 08:28 AM
- 447 views
Bring Me Sunshine...
by AG McCluskey in Zongo's Cancer Diaries
The latest Public Health statement is about the dangers of suntanning. But what IS a suntan? And how could it lead to cancer...?... Read more »
NICE. (2016) Sunlight exposure: risks and benefits. National Institute for Health . info:/
Newton-Bishop, J., Chang, Y., Elliott, F., Chan, M., Leake, S., Karpavicius, B., Haynes, S., Fitzgibbon, E., Kukalizch, K., Randerson-Moor, J.... (2011) Relationship between sun exposure and melanoma risk for tumours in different body sites in a large case-control study in a temperate climate. European Journal of Cancer, 47(5), 732-741. DOI: 10.1016/j.ejca.2010.10.008
- January 9, 2016
- 03:36 PM
- 660 views
Turning to the “Infected Jelly” to Treat Ebola
by Pranab Chatterjee in Scepticemia
The NEJM has come out with a very interesting paper: Evaluation of Convalescent Plasma for Ebola Virus Disease in Guinea. The explosive outbreak of Ebola Virus Disease in West Africa last year had hijacked the headlines and media space in a big way. Multiple solutions were touted, including the vaccine trial STRIVE. Few articles, however, looked…... Read more »
van Griensven J, Edwards T, de Lamballerie X, Semple MG, Gallian P, Baize S, Horby PW, Raoul H, Magassouba N, Antierens A.... (2016) Evaluation of Convalescent Plasma for Ebola Virus Disease in Guinea. The New England journal of medicine, 374(1), 33-42. PMID: 26735992
- January 9, 2016
- 01:28 PM
- 964 views
If Colistin Goes, Can Carbapenems be Far Behind?
by Pranab Chatterjee in Scepticemia
I wrote about the disaster-in-the-making discovery of transmissible resistance to colistin, a last resort antibiotic, when the Lancet Infectious Diseases published a paper based on data coming out from surveillance in China. At that point of time, the isolation of the transmissible gene providing resistance (mcr1 gene) gained a lot of attention. Maryn McKenna’s blog post went…... Read more »
Poirel, L., Kieffer, N., Liassine, N., Thanh, D., & Nordmann, P. (2016) Plasmid-mediated carbapenem and colistin resistance in a clinical isolate of Escherichia coli. The Lancet Infectious Diseases. DOI: 10.1016/S1473-3099(16)00006-2
- January 8, 2016
- 11:01 AM
- 602 views
Devil in a bottle?
by AG McCluskey in Zongo's Cancer Diaries
The media are on the warpath again! This time, it's alcohol. But is this new?... Read more »
Department of Health. (2016) Alcohol Guidelines Review – Report from the Guidelines development group to the UK Chief Medical Officers. www.gov.uk. info:/
Bagnardi, V., Rota, M., Botteri, E., Tramacere, I., Islami, F., Fedirko, V., Scotti, L., Jenab, M., Turati, F., Pasquali, E.... (2012) Light alcohol drinking and cancer: a meta-analysis. Annals of Oncology, 24(2), 301-308. DOI: 10.1093/annonc/mds337
- October 7, 2015
- 11:30 PM
- 692 views
Social Class Differences in Mental Health: Do Parenting Style and Friendship Play a Role?
by Mark Rubin in Mark Rubin's Social Psychology Research Blog
It is now well-established that social class is positively related to mental health. However, researchers remain unclear about the specific processes that underlie the relation between social class and depression. In some recent research, we investigated the potential roles of parenting style and friendship in explaining the relationship between social class and mental health.... Read more »
Rubin, M., & Kelly, B. (2015) A cross-sectional investigation of parenting style and friendship as mediators of the relation between social class and mental health in a university community. International Journal for Equity in Health, 14(1), 1-11. DOI: 10.1186/s12939-015-0227-2
- August 23, 2015
- 08:00 PM
- 540 views
Courting Disaster
by Angela Reisetter in Steeped in Science
A response to the measles death in the U.S. in July 2015, in defense of vaccination.... Read more »
Mina MJ, Metcalf CJ, de Swart RL, Osterhaus AD, & Grenfell BT. (2015) Long-term measles-induced immunomodulation increases overall childhood infectious disease mortality. Science (New York, N.Y.), 348(6235), 694-9. PMID: 25954009
- July 29, 2015
- 02:09 PM
- 1,194 views
The “Invisible Web” Undermines Health Information Privacy
by Jalees Rehman in The Next Regeneration
What do the third parties do with your data? We do not really know because the laws and regulations are rather fuzzy here. We do know that Google, Facebook and Twitter primarily make money by advertising so they could potentially use your info and customize the ads you see. Just because you visited a page on breast cancer does not mean that the "Invisible Web" knows your name and address but they do know that you have some interest in breast cancer. It would make financial sense to sen........ Read more »
Libert, T. (2015) Privacy implications of health information seeking on the web. Communications of the ACM, 58(3), 68-77. DOI: 10.1145/2658983
- June 19, 2015
- 12:23 PM
- 500 views
6 Realities of Genomic Research
by Daniel Koboldt in Massgenomics
The rise of next-generation sequencing has worked wonders for the field of genetics and genomics. It’s also generated a considerable amount of hype about the power of genome sequencing, particularly the possibility of individualized medicine based on genetic information. The rapid advances in technology — most recently, the Illumina X Ten system — have made […]... Read more »
Rehm HL, Berg JS, Brooks LD, Bustamante CD, Evans JP, Landrum MJ, Ledbetter DH, Maglott DR, Martin CL, Nussbaum RL.... (2015) ClinGen--the Clinical Genome Resource. The New England journal of medicine, 372(23), 2235-42. PMID: 26014595
- March 31, 2015
- 05:45 AM
- 1,322 views
African-Americans Receive Heart Transplants at Hospitals With Poor Performance Track Records
by Jalees Rehman in The Next Regeneration
About five million people in the US suffer from heart failure, and approximately half of them die within five years of being diagnosed. Only about 2,500 hundred people a year receive a heart transplant – the treatment of last resort. A new heart can be life-saving, but it is also life-changing. Even under the best conditions, the surgery is complex, and recovery carries a heavy physical and emotional burden.
... Read more »
Kilic, A., Higgins, R., Whitson, B., & Kilic, A. (2015) Racial Disparities in Outcomes of Adult Heart Transplantation. Circulation, 131(10), 882-889. DOI: 10.1161/CIRCULATIONAHA.114.011676
- March 30, 2015
- 11:25 AM
- 684 views
One Parent,Two Parents and Child Well-Being
by William Yates, M.D. in Brain Posts
The structure of the family in the United States and other countries is changing. This change has occurred over a relatively brief period of time. Data noted in the study I am reviewing today shows that between 1970 and 2013 in the U.S.:Percentage of children living with two parents dropped 24%Percentage of children living with a single mother increased to 23.7%Percentage of children living with a single father quadrupled to 4.1%Percentage of children living with a grandparent doubled to 6......... Read more »
Krueger PM, Jutte DP, Franzini L, Elo I, & Hayward MD. (2015) Family structure and multiple domains of child well-being in the United States: a cross-sectional study. Population health metrics, 6. PMID: 25729332
- February 23, 2015
- 09:20 PM
- 1,045 views
Exercise Medicine is Ancient History
by Rodney Steadman in Gravity's Pull
Exercise was used as medicine at least 2600 years ago.... Read more »
Tipton, C. (2014) The history of "Exercise Is Medicine" in ancient civilizations. AJP: Advances in Physiology Education, 38(2), 109-117. DOI: 10.1152/advan.00136.2013
- February 2, 2015
- 08:00 AM
- 1,028 views
Integrating self-collecting HPV DNA testing with community health worker programs increases cervical screening coverage
by Betty Zou in Eat, Read, Science
In the study published in Lancet Global Health, researchers found that when community health workers offered self-collecting HPV tests to women, participation rates increased four-fold. Human papillomavirus, or HPV, DNA testing is emerging as a viable alternative to Pap smears in low-resource settings. Earlier studies have shown that HPV DNA testing is as sensitive as conventional Pap smears in detecting cervical disease. An additional benefit of HPV DNA testing is the potential for self-samplin........ Read more »
Arrossi S, Thouyaret L, Herrero R, Campanera A, Magdaleno A, Cuberli M, Barletta P, Laudi R, Orellana L, & EMA Study team. (2015) Effect of self-collection of HPV DNA offered by community health workers at home visits on uptake of screening for cervical cancer (the EMA study): a population-based cluster-randomised trial. The Lancet. Global health, 3(2). PMID: 25617202
Ginsburg, O. (2013) Breast and cervical cancer control in low and middle-income countries: Human rights meet sound health policy. Journal of Cancer Policy, 1(3-4). DOI: 10.1016/j.jcpo.2013.07.002
- January 22, 2015
- 02:06 PM
- 1,947 views
Black Tar Heroin: Lower HIV Transmission vs Higher Bacterial Infections?
by Pranab Chatterjee in Scepticemia
The rise of street-cut, unsanitary preparations of Black Tar Heroin has allegedly reduced HIV transmission but at the cost of higher numbers of fatal, bacterial infections, notably botulism, clusters of which have been regularly identified in California.... Read more »
Ciccarone, D., & Bourgois, P. (2003) Explaining the Geographical Variation of HIV Among Injection Drug Users in the United States. Substance Use , 38(14), 2049-2063. DOI: 10.1081/JA-120025125
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