Post List

  • April 29, 2017
  • 05:18 AM
  • 31 views

When grandmothers smoked during pregnancy...

by Paul Whiteley in Questioning Answers

Please, do not smoke during pregnancyALSPAC - the Avon Longitudinal Study of Parents and Children - continues to give in research terms as today I want to mention the findings reported by Jean Golding and colleagues [1] (open-access) observing "an association between maternal grandmother smoking in pregnancy and grand daughters having adverse scores in Social Communication and Repetitive Behaviour measures that are independently predictive of diagnosed autism."The study results have garnere........ Read more »

Golding J, Ellis G, Gregory S, Birmingham K, Iles-Caven Y, Rai D, & Pembrey M. (2017) Grand-maternal smoking in pregnancy and grandchild's autistic traits and diagnosed autism. Scientific reports, 46179. PMID: 28448061  

  • April 28, 2017
  • 03:04 AM
  • 45 views

Autism, pregnancy maternal immune activation and vitamin D?

by Paul Whiteley in Questioning Answers

Today's post is a bit of a mash-up, drawing on two articles quite recently published in the peer-reviewed science domain.The first is by Stephanie Vuillermot and colleagues [1] (open-access) suggesting that "early dietary supplementation with vitamin D may open new avenues for a successful attenuation or even prevention of neurodevelopmental disorders following maternal inflammation during pregnancy." These findings have also received some media attention (see here for example) and continue........ Read more »

  • April 27, 2017
  • 08:49 AM
  • 57 views

Code Orange for the Bengal Tiger!

by Jente Ottenburghs in Evolutionary Stories

Genetic study highlights challenging conservation of the Bengal Tiger in India.... Read more »

  • April 27, 2017
  • 02:57 AM
  • 69 views

Is screen time a risk factor for ADHD?

by Paul Whiteley in Questioning Answers

The findings reported by Vivien Suchert and colleagues [1] observing that "screen time, but not other non-screen-based sedentary activities should be considered as being a risk factor for ADHD [attention-deficit hyperactivity disorder]" taps into long-running debates on whether our societal obsession with watching, clicking and swiping might not be 'a totally positive thing' when it comes to psychological development, health and wellbeing.Yes, I know this is a complicated area ful........ Read more »

  • April 26, 2017
  • 03:02 AM
  • 91 views

Hornig, Lipkin and chronic fatigue syndrome again

by Paul Whiteley in Questioning Answers

Drs Mady Hornig and Ian Lipkin once again provide some fodder for this blog, continuing one of their important research themes on how chronic fatigue syndrome (CFS) (sometimes also referred to as myalgic encephalomyelitis, ME) might show some important immune-related issues [1].This research tag-team and the teams of dedicated scientists who surround them are making some real progress with regards to the idea that ME/CFS is a physical condition (not psychosomatic and not 'biopsychosocial') ........ Read more »

  • April 25, 2017
  • 01:46 PM
  • 99 views

Editors of Brazilian journals – a hard life that is getting harder! [Originally published as the editorial in Anais da Academia Brasileira de Ciências vol. 89 no. 1]

by SciELO in SciELO in Perspective

The financing of journals of Brazil can be improved by extending the validity period of research grants, in order to allow publishers a better plan for articles publication. An editorial written by Alexander Kellner in the first issue of 2017 of Anais da Academia Brasileira de Ciências examines the challenge faced by editors of journals of Brazil and highlights their hard work in attracting relevant manuscripts, seeking to achieve ever greater levels of excellence and internationalization. R........ Read more »

CORDEIRO, Y., & SCHUCK, P. (2015) Hot Topics in Biomedical Sciences. Anais da Academia Brasileira de Ciências, 87(2), 1271-1272. DOI: 10.1590/0001-376520158722  

Vasconcelos, S., Sorenson, M., Watanabe, E., Foguel, D., & Palácios, M. (2015) Brazilian Science and Research Integrity: Where are We? What Next?. Anais da Academia Brasileira de Ciências, 87(2), 1259-1269. DOI: 10.1590/0001-3765201520150165  

  • April 25, 2017
  • 07:02 AM
  • 72 views

The Brightness Temperature of the Quiet Solar Chromosphere at 2.6 mm by Kazumasa Iwai et al

by CESRA in Solar Radio Science

The brightness temperature of the Sun constitutes a basic property of the solar atmosphere. The main emission mechanism of the Sun at millimeter and submillimeter wavelengths is thermal free–free emission from the chromosphere, which is an atmospheric layer with a temperature ranging between 6000 to 20,000 K. The opacity of thermal free–free emission depends on the temperature and density in the emission region. In addition, the Rayleigh– Jeans law is applicable [...]... Read more »

Iwai, K., Shimojo, M., Asayama, S., Minamidani, T., White, S., Bastian, T., & Saito, M. (2017) The Brightness Temperature of the Quiet Solar Chromosphere at 2.6 mm. Solar Physics, 292(1). DOI: 10.1007/s11207-016-1044-5  

  • April 25, 2017
  • 03:15 AM
  • 109 views

Who'd have thunk it: physical activity inversely associated with BMI and body fat percentage

by Paul Whiteley in Questioning Answers

"In this sample of middle-aged adults, drawn from the general population, physical activity was inversely associated with BMI [body mass index] and body fat percentage. For people with the same BMI, those who were more active had a lower body fat percentage."Those were the conclusions made by Kathryn Bradbury and colleagues [1] (open-access) drawing on data derived from "cross-sectional analysis of participants recruited into UK Biobank in 2006–2010." Said results continue a res........ Read more »

  • April 25, 2017
  • 02:16 AM
  • 108 views

Will technology make language rights obsolete?

by Dave Sayers in Language on the Move

Something has been nagging at me recently. I read a lot of tech news, and it seems automated translation is...... Read more »

  • April 24, 2017
  • 04:22 AM
  • 102 views

Promising mouse model for Ngly1 deficiency

by adam phillips in It Ain't Magic

A recent study of Ngly1 deficient mice used a secondary knockout to create double knockouts with symptoms similar to human NGLY1 deficiency.... Read more »

  • April 24, 2017
  • 03:05 AM
  • 108 views

Sensory issues in adult ADHD controlling for autistic symptoms...

by Paul Whiteley in Questioning Answers

I was intrigued to read the paper by Bijlenga and colleagues [1] reporting on "the prevalence of sensory hyper- and hyposensitivity among adults with ADHD [attention-deficit hyperactivity disorder], controlling for autistic symptoms."The authors concluded that among their cohort of over 100 adults diagnosed with ADHD, both sensory hyper- and hyposensitivity symptoms as described by response to the Adolescent/Adult Sensory Profile-NL (AASP-NL), were over-represented compared w........ Read more »

Bijlenga D, Tjon-Ka-Jie JY, Schuijers F, & Kooij JJ. (2017) Atypical sensory profiles as core features of adult ADHD, irrespective of autistic symptoms. European psychiatry : the journal of the Association of European Psychiatrists, 51-57. PMID: 28371743  

  • April 22, 2017
  • 11:30 PM
  • 160 views

Intrinsic Motivation Is Caused by Achievement

by Joshua Fisher in Text Savvy

Education interventions (specifically those dealing with mathematics education) designed to increase achievement may be better uses of time than those designed to increase intrinsic motivation.... Read more »

  • April 22, 2017
  • 06:14 AM
  • 134 views

Autistic adults as critical autism experts (with research caveats)

by Paul Whiteley in Questioning Answers

"Findings suggest that autistic adults should be considered autism experts and involved as partners in autism research."That was the conclusion reached in the paper by Kristen Gillespie-Lynch and colleagues [1] (open-access) reporting on the results of an online survey assessing "autism knowledge and stigma among 636 adults with varied relationships to autism, including autistic people and nuclear family members." Among the various groups of people who contributed to the survey, several vie........ Read more »

Gillespie-Lynch, K., Kapp, S., Brooks, P., Pickens, J., & Schwartzman, B. (2017) Whose Expertise Is It? Evidence for Autistic Adults as Critical Autism Experts. Frontiers in Psychology. DOI: 10.3389/fpsyg.2017.00438  

  • April 21, 2017
  • 06:26 AM
  • 133 views

History of neuroscience: John Hughlings Jackson

by neurosci in Neuroscientifically Challenged















In 1860, when John Hughlings Jackson was just beginning his career as a physician, neurology did not yet exist as a medical specialty. In fact, at that time there had been little attention paid to developing a standard approach to treating patients with neurological disease. Such an approach was one of Jackson's greatest contributions to neuroscience. He advocated for examining each patient individually in an attempt to iden........ Read more »

York GK, Steinberg DA. (2007) An Introduction to the Life and Work of John Hughlings Jackson. Med Hist Suppl., 3-34. info:/

  • April 21, 2017
  • 04:32 AM
  • 162 views

Parental exposures and risk of offspring autism: some curious details

by Paul Whiteley in Questioning Answers

"Overall, our results were consistent with no positive association between parental asthmagen exposure and ASD [autism spectrum disorder] in the children."So said the findings reported by Alison Singer and colleagues [1] (open-access) continuing a research theme from this group [2] looking at whether "parental workplace exposures to risk factors for asthma (“asthmagens”)" might have relevance to offspring risk for autism.Based on data derived from some of those oh-so-important Scan........ Read more »

  • April 20, 2017
  • 05:19 AM
  • 165 views

DHM attenuates obesity-induced slow-twitch-fiber decrease via FLCN/FNIP1/AMPK pathway

by Joana Guedes in BHD Research Blog

Obesity is often associated with decreases in the proportion of skeletal muscle slow-twitch fibers and insulin sensitivity. Slow-twitch fibers are rich in mitochondria and utilize fatty acid oxidative phosphorylation for energy production. In their new study, Zhou et al. (2017) explore the role of the FLCN/FNIP1/AMPK signalling pathway in obesity-induced reductions in slow-twitch fibers and insulin sensitivity in skeletal muscle using high-fat-diet-induced (HFD) obese mice, ob/ob mutant mice, an........ Read more »

  • April 20, 2017
  • 04:37 AM
  • 156 views

"a gradual decline in recorded diagnoses of CFS/ME since 2001"?

by Paul Whiteley in Questioning Answers

The quote forming the title of today's post comes from the paper by Simon Collin and colleagues [1] (open-access available here) who, based on analysis of the UK "Clinical Practice Research Datalink (CPRD), formerly known as the General Practice Research Database (GPRD)" set out to look at the "Incidence of CFS/ME [chronic fatigue syndrome/ myalgic encephalomyelitis], FM [fibromyalgia], post-viral fatigue syndrome (PVFS), and asthenia/debility." I say incidence but that last sentence s........ Read more »

  • April 19, 2017
  • 04:31 AM
  • 176 views

Allergy and ADHD meta-analysed and guess what...

by Paul Whiteley in Questioning Answers

"Reports of frequent manifestation of allergic diseases in children with attention deficit hyperactivity disorder (ADHD) have been the subject of mounting clinical interest."OK, go on."The objective of this study was to compile and assess available studies on the association between ADHD and allergic diseases in children."And your findings... "children with ADHD are more likely to have asthma, allergic rhinitis, atopic dermatitis, and allergic conjunctivitis than their counterparts. Intervention........ Read more »

  • April 18, 2017
  • 04:21 AM
  • 197 views

"Asthma was associated with increased risk for schizophrenia"

by Paul Whiteley in Questioning Answers

'Big data' Taiwan is once again the topic of a post on this blog as the results published by Wei-Chen Wang and colleagues [1] (open-access available here) receive an airing, specifically that: "Asthma was associated with increased risk for schizophrenia."There are some common themes attached to these findings. Taiwan is already a research-favourite place on this blog as a result of their use of the National Health Insurance Research Database (NHIRD) for various research purposes. I can't na........ Read more »

Wang WC, Lu ML, Chen VC, Ng MH, Huang KY, Hsieh MH, Hsieh MJ, McIntyre RS, Lee Y, & Lee CT. (2017) Asthma, corticosteroid use and schizophrenia: A nationwide population-based study in Taiwan. PloS one, 12(3). PMID: 28350822  

  • April 17, 2017
  • 03:00 PM
  • 210 views

The continuing trials and tribulations of PACE

by Paul Whiteley in Questioning Answers

I honestly hadn't intended talking about the PACE trial - "pacing, graded activity, and cognitive behaviour therapy: a randomised evaluation" in relation to chronic fatigue syndrome (CFS) - quite so much on this blog. Others have done it so much better than I ever could.My interest however keeps being piqued in relation to the results originally produced suggesting that: "CBT [cognitive behaviour therapy] and GET [graded exercise therapy] can safely be added to SMC to mo........ Read more »

White, P., Chalder, T., Sharpe, M., Angus, B., Baber, H., Bavinton, J., Burgess, M., Clark, L., Cox, D., DeCesare, J.... (2017) Response to the editorial by Dr Geraghty. Journal of Health Psychology, 2147483647. DOI: 10.1177/1359105316688953  

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