Christen Rune Stensvold

52 posts · 25,263 views

I hold a PhD in Health Sciences and have been working in the field of clinical microbiology for almost 10 years. My research deals with the diagnosis, epidemiology, clinical significance, genetic diversity, and taxonomy of common intestinal 'amoebae' with special emphasis on Blastocystis. Since 2006, I have published about 60 scientific, peer-reviewed papers, of which 25 or so are Blastocystis-specific papers. I'm based at the Department of Microbiology and Infection Control, Statens Serum Institut, Copenhagen, Denmark and did my post doc at London School of Hygiene & Tropical Medicine. F1000 Associate Faculty Member (since 09 December 2009). ORCID # 0000-0002-1417-7048 Facebook page: https://www.facebook.com/pages/Blastocystis-Parasite-Blog/161212370703270

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  • April 19, 2014
  • 07:34 AM
  • 4 views

Typing Method for Cryptosporidium Meleagridis

by Christen Rune Stensvold in Christen Rune Stensvold

You can read about the development and use of a highly applicable typing method for C. meleagridis isolates in a newly published paper in Journal of Clinical Microbiology.... Read more »

  • April 19, 2014
  • 07:34 AM
  • 3 views

Typing Method for Cryptosporidium Meleagridis

by Christen Rune Stensvold in Blastocystis Parasite Blog

You can read about the development and use of a highly applicable typing method for C. meleagridis isolates in a newly published paper in Journal of Clinical Microbiology.... Read more »

  • April 10, 2014
  • 01:16 AM
  • 59 views

Resources For Blastocystis Epidemiology Research

by Christen Rune Stensvold in Blastocystis Parasite Blog

An inventory of useful free online tools for studying the molecular epidemiology of Blastocystis.... Read more »

Alfellani MA, Taner-Mulla D, Jacob AS, Imeede CA, Yoshikawa H, Stensvold CR, & Clark CG. (2013) Genetic diversity of blastocystis in livestock and zoo animals. Protist, 164(4), 497-509. PMID: 23770574  

Alfellani MA, Stensvold CR, Vidal-Lapiedra A, Onuoha ES, Fagbenro-Beyioku AF, & Clark CG. (2013) Variable geographic distribution of Blastocystis subtypes and its potential implications. Acta tropica, 126(1), 11-8. PMID: 23290980  

Clark CG, van der Giezen M, Alfellani MA, & Stensvold CR. (2013) Recent developments in Blastocystis research. Advances in parasitology, 1-32. PMID: 23548084  

Stensvold CR, Suresh GK, Tan KS, Thompson RC, Traub RJ, Viscogliosi E, Yoshikawa H, & Clark CG. (2007) Terminology for Blastocystis subtypes--a consensus. Trends in parasitology, 23(3), 93-6. PMID: 17241816  

  • April 1, 2014
  • 09:05 PM
  • 69 views

This Month In Blastocystis Research (MAR 2014)

by Christen Rune Stensvold in Blastocystis Parasite Blog

Is Blastocystis a consistent finding in Senegalese children? Novel data seem to suggest so.... Read more »

  • March 16, 2014
  • 03:44 AM
  • 130 views

What's In A Name?

by Christen Rune Stensvold in Blastocystis Parasite Blog

Blastocystis is a parasite. But what makes a parasite, and are all parasites 'bad'?... Read more »

  • February 28, 2014
  • 02:39 PM
  • 284 views

This Month In Blastocystis Research (FEB 2014) - The Protease Edition

by Christen Rune Stensvold in Blastocystis Parasite Blog

The February issue of This Month In Blastocystis Research is mostly about Blastocystis proteases and their potential clinical significance. ... Read more »

Fayer R, Elsasser T, Gould R, Solano G, Urban J Jr, & Santin M. (2014) Blastocystis tropism in the pig intestine. Parasitology research. PMID: 24535732  

Denoeud F, Roussel M, Noel B, Wawrzyniak I, Da Silva C, Diogon M, Viscogliosi E, Brochier-Armanet C, Couloux A, Poulain J.... (2011) Genome sequence of the stramenopile Blastocystis, a human anaerobic parasite. Genome biology, 12(3). PMID: 21439036  

Olivo-Diaz A, Romero-Valdovinos M, Gudiño-Ramirez A, Reyes-Gordillo J, Jimenez-Gonzalez DE, Ramirez-Miranda ME, Martinez-Flores WA, Martinez-Hernandez F, Flisser A, & Maravilla P. (2012) Findings related to IL-8 and IL-10 gene polymorphisms in a Mexican patient population with irritable bowel syndrome infected with Blastocystis. Parasitology research, 111(1), 487-91. PMID: 22287022  

Puthia MK, Vaithilingam A, Lu J, & Tan KS. (2005) Degradation of human secretory immunoglobulin A by Blastocystis. Parasitology research, 97(5), 386-9. PMID: 16151742  

Wawrzyniak I, Texier C, Poirier P, Viscogliosi E, Tan KS, Delbac F, & El Alaoui H. (2012) Characterization of two cysteine proteases secreted by Blastocystis ST7, a human intestinal parasite. Parasitology international, 61(3), 437-42. PMID: 22402106  

Sio SW, Puthia MK, Lee AS, Lu J, & Tan KS. (2006) Protease activity of Blastocystis hominis. Parasitology research, 99(2), 126-30. PMID: 16518611  

  • February 3, 2014
  • 01:55 PM
  • 188 views

This Month In Blastocystis Research (JAN 2014)

by Christen Rune Stensvold in Blastocystis Parasite Blog

This Month In Blastocystis Research is introducing the possible benefits of polyparasitism (!) and pulls out an example of a potentially protecting effect of Blastocystis.... Read more »

Franke MF, Del Castillo H, Pereda Y, Lecca L, Fuertes J, Cárdenas L, Becerra MC, Bayona J, & Murray M. (2013) Parasite Infection and Tuberculosis Disease among Children: A Case-Control Study. The American journal of tropical medicine and hygiene. PMID: 24379242  

Archambaud C, Sismeiro O, Toedling J, Soubigou G, Bécavin C, Lechat P, Lebreton A, Ciaudo C, & Cossart P. (2013) The intestinal microbiota interferes with the microRNA response upon oral Listeria infection. mBio, 4(6). PMID: 24327339  

  • December 11, 2013
  • 02:11 AM
  • 276 views

Molecular Epidemiology: Developing a Language

by Christen Rune Stensvold in Blastocystis Parasite Blog

Standardised methods and broadly accepeted reference data are the bread and butter of molecular epidemiological studies of infectious organisms. This post highlights some of the issues related to molecular epidemiology terminology and draws parallels between research in Blastocystis and Cryptosporidium.... Read more »

Alfellani MA, Taner-Mulla D, Jacob AS, Imeede CA, Yoshikawa H, Stensvold CR, & Clark CG. (2013) Genetic diversity of blastocystis in livestock and zoo animals. Protist, 164(4), 497-509. PMID: 23770574  

Stensvold CR, Suresh GK, Tan KS, Thompson RC, Traub RJ, Viscogliosi E, Yoshikawa H, & Clark CG. (2007) Terminology for Blastocystis subtypes--a consensus. Trends in parasitology, 23(3), 93-6. PMID: 17241816  

Xiao L, Ryan UM, Fayer R, Bowman DD, & Zhang L. (2012) Cryptosporidium tyzzeri and Cryptosporidium pestis: which name is valid?. Experimental parasitology, 130(3), 308-9. PMID: 22230707  

  • December 4, 2013
  • 06:42 PM
  • 261 views

This Month in Blastocystis Research (NOV 2013)

by Christen Rune Stensvold in Blastocystis Parasite Blog

This Month in Blastocystis Research (NOV 2013)is mainly about new diagnostics and various treatment options.... Read more »

Roberts T, Ellis J, Harkness J, Marriott D, & Stark D. (2013) Treatment failure in patients with chronic Blastocystis infection. Journal of medical microbiology. PMID: 24243286  

  • November 22, 2013
  • 05:30 PM
  • 263 views

Do IBS Patients Lack Blastocystis and Dientamoeba??

by Christen Rune Stensvold in Blastocystis Parasite Blog

Healthy individuals appear to be more frequent carriers of the two parasites Blastocystis and Dientamoeba fragilis. We would like to know why and what the public health implications are of this.... Read more »

  • November 5, 2013
  • 10:56 AM
  • 248 views

A Shift of Paradigm in Blastocystis Research? Free paper in Trends in Parasitology!

by Christen Rune Stensvold in Blastocystis Parasite Blog

Opinion paper on Blastocystis in 'Trends in Parasitology' free for download all of November 2013.... Read more »

  • November 3, 2013
  • 04:13 AM
  • 284 views

This Month in Blastocystis Research (OCT 2013)

by Christen Rune Stensvold in Blastocystis Parasite Blog

A post about a selection of papers related to Blastocystis research emerging in October 2013.... Read more »

Maas L, Dorigo-Zetsma JW, de Groot CJ, Bouter S, Plötz FB, & van Ewijk BE. (2013) Detection of intestinal protozoa in paediatric patients with gastrointestinal symptoms by multiplex real-time PCR. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. PMID: 24131443  

  • October 16, 2013
  • 08:30 PM
  • 274 views

Dying to know about Dientamoeba?

by Christen Rune Stensvold in Blastocystis Parasite Blog

Similar to Blastocystis, Dientamoeba fragilis is a very common parasite in countries where other intestinal parasites are of low endemic occurrence. We are exploring the clinical significance of these parasites.... Read more »

Engsbro AL, Stensvold CR, Nielsen HV, & Bytzer P. (2012) Treatment of Dientamoeba fragilis in patients with irritable bowel syndrome. The American journal of tropical medicine and hygiene, 87(6), 1046-52. PMID: 23091195  

Ogren J, Dienus O, Löfgren S, Iveroth P, & Matussek A. (2013) Dientamoeba fragilis DNA detection in Enterobius vermicularis eggs. Pathogens and disease. PMID: 23893951  

Stark DJ, Beebe N, Marriott D, Ellis JT, & Harkness J. (2006) Dientamoebiasis: clinical importance and recent advances. Trends in parasitology, 22(2), 92-6. PMID: 16380293  

Stark D, Barratt J, Roberts T, Marriott D, Harkness J, & Ellis J. (2010) A review of the clinical presentation of dientamoebiasis. The American journal of tropical medicine and hygiene, 82(4), 614-9. PMID: 20348509  

Stensvold CR, Clark CG, & Röser D. (2013) Limited intra-genetic diversity in Dientamoeba fragilis housekeeping genes. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, 284-6. PMID: 23681023  

Stensvold CR, Lewis HC, Hammerum AM, Porsbo LJ, Nielsen SS, Olsen KE, Arendrup MC, Nielsen HV, & Mølbak K. (2009) Blastocystis: unravelling potential risk factors and clinical significance of a common but neglected parasite. Epidemiology and infection, 137(11), 1655-63. PMID: 19393117  

  • September 4, 2013
  • 05:01 PM
  • 290 views

Yes, we do take orders!

by Christen Rune Stensvold in Blastocystis Parasite Blog

The Laboratory of Parasitology, Statens Serum Institut, is now seeking to make diagnostic services available for customers outside Denmark. Doctors - and to some extent private persons - can order analyses directly, and it will also be possible for researchers to outsource diagnostic work to our laboratory.... Read more »

  • August 30, 2013
  • 10:27 PM
  • 358 views

This Month In Blastocystis Research (AUG)

by Christen Rune Stensvold in Blastocystis Parasite Blog

Quite a few papers relevant to Blastocystis research have made it to PubMed over the past month! Therefore, the August version of 'This Month in Blastocystis Research' is more like a list of papers short descriptions/comments, rather than one or two actual paper reviews.... Read more »

Li J, Deng T, Li X, Cao G, Li X, & Yan Y. (2013) A rat model to study Blastocytis subtype 1 infections. Parasitology research. PMID: 23892480  

Parija SC. (2013) Blastocystis: Status of its pathogenicity. Tropical parasitology, 3(1), 1. PMID: 23961433  

Sekar U, & Shanthi M. (2013) Blastocystis: Consensus of treatment and controversies. Tropical parasitology, 3(1), 35-9. PMID: 23961439  

Parija SC, & Jeremiah S. (2013) Blastocystis: Taxonomy, biology and virulence. Tropical parasitology, 3(1), 17-25. PMID: 23961437  

Ramírez JD, Sánchez LV, Bautista DC, Corredor AF, Flórez AC, & Stensvold CR. (2013) Blastocystis subtypes detected in humans and animals from Colombia. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases. PMID: 23886615  

Wang W, Cuttell L, Bielefeldt-Ohmann H, Inpankaew T, Owen H, & Traub RJ. (2013) Diversity of Blastocystis subtypes in dogs in different geographical settings. Parasites , 215. PMID: 23883734  

  • July 29, 2013
  • 02:58 PM
  • 399 views

Birds of America

by Christen Rune Stensvold in Blastocystis Parasite Blog

This blog post highlights Blastocystis subtypes identified in birds on a global scale, in particular in passerine birds of America.... Read more »

Ramírez JD, Sánchez LV, Bautista DC, Corredor AF, Flórez AC, & Stensvold CR. (2013) Blastocystis subtypes detected in humans and animals from Colombia. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases. PMID: 23886615  

Alfellani MA, Taner-Mulla D, Jacob AS, Imeede CA, Yoshikawa H, Stensvold CR, & Clark CG. (2013) Genetic diversity of blastocystis in livestock and zoo animals. Protist, 164(4), 497-509. PMID: 23770574  

Stensvold CR, Alfellani M, & Clark CG. (2012) Levels of genetic diversity vary dramatically between Blastocystis subtypes. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, 12(2), 263-73. PMID: 22116021  

Stensvold CR, Alfellani MA, Nørskov-Lauritsen S, Prip K, Victory EL, Maddox C, Nielsen HV, & Clark CG. (2009) Subtype distribution of Blastocystis isolates from synanthropic and zoo animals and identification of a new subtype. International journal for parasitology, 39(4), 473-9. PMID: 18755193  

  • July 22, 2013
  • 01:10 PM
  • 337 views

My 'Thoughts on Blastocystis' now as eBook in Amazon

by Christen Rune Stensvold in Blastocystis Parasite Blog

I started blogging about Blastocystis in March 2012, and I thought I’d publish some of the more elaborate posts in chronological order as a separate eBook with some minor re-editing, - sort of a ‘Blastocystis Research Diary’. The Blastocystis Parasite Blog has allowed me to vent new hypotheses and some alternative views on Blastocystis and its role in health and disease.... Read more »

Clark CG, van der Giezen M, Alfellani MA, & Stensvold CR. (2013) Recent developments in Blastocystis research. Advances in parasitology, 1-32. PMID: 23548084  

  • July 17, 2013
  • 06:30 PM
  • 400 views

ICOP XIV in Vancouver 28 July to 2 August 2013

by Christen Rune Stensvold in Blastocystis Parasite Blog

The 14th International Congress on Protistology takes place in Vancouver later this month. Here are some teasers, including some on Blastocystis.... Read more »

Denoeud F, Roussel M, Noel B, Wawrzyniak I, Da Silva C, Diogon M, Viscogliosi E, Brochier-Armanet C, Couloux A, Poulain J.... (2011) Genome sequence of the stramenopile Blastocystis, a human anaerobic parasite. Genome biology, 12(3). PMID: 21439036  

  • July 10, 2013
  • 08:30 PM
  • 407 views

This Month In Blastocystis Research (JUL)

by Christen Rune Stensvold in Blastocystis Parasite Blog

This Month In Blastocystis Research (JUL 2013) focuses on a symposium on Blastocystis that has been published in the open access journal Tropical Parasitology.... Read more »

  • June 21, 2013
  • 10:53 PM
  • 487 views

This Month In Blastocystis Research

by Christen Rune Stensvold in Blastocystis Parasite Blog

The universe of Blastocystis is continuously expanding. Here we report of three novel subtypes. We also suggest that livestock is not a major contributor to human Blastocystis infection.... Read more »

Alfellani MA, Taner-Mulla D, Jacob AS, Imeede CA, Yoshikawa H, Stensvold CR, & Clark CG. (2013) Genetic Diversity of Blastocystis in Livestock and Zoo Animals. Protist, 164(4), 497-509. PMID: 23770574  

Alfellani MA, Stensvold CR, Vidal-Lapiedra A, Onuoha ES, Fagbenro-Beyioku AF, & Clark CG. (2013) Variable geographic distribution of Blastocystis subtypes and its potential implications. Acta tropica, 126(1), 11-8. PMID: 23290980  

Alfellani MA, Jacob AS, Perea NO, Krecek RC, Taner-Mulla D, Verweij JJ, Levecke B, Tannich E, Clark CG, & Stensvold CR. (2013) Diversity and distribution of Blastocystis sp. subtypes in non-human primates. Parasitology, 140(8), 966-71. PMID: 23561720  

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