Artem Kaznatcheev

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  • March 31, 2015
  • 11:45 PM
  • 200 views

Operationalizing the local environment for replicator dynamics

by Artem Kaznatcheev in Evolutionary Games Group

Recently, Jake Taylor-King arrived in Tampa and last week we were brainstorming some projects to work on together. In the process, I dug up an old idea I’ve been playing with as my understanding of the Ohtsuki-Nowak transform matured. The basic goal is to work towards an operational account of spatial structure without having to […]... Read more »

Ohtsuki, H., & Nowak, M. (2006) The replicator equation on graphs. Journal of Theoretical Biology, 243(1), 86-97. DOI: 10.1016/j.jtbi.2006.06.004  

  • March 16, 2015
  • 11:45 PM
  • 261 views

Pairing tools and problems: a lesson from the methods of mathematics and the Entscheidungsproblem

by Artem Kaznatcheev in Evolutionary Games Group

Three weeks ago it was my lot to present at the weekly integrated mathematical oncology department meeting. Given the informal setting, I decided to grab one gimmick and run with it. I titled my talk: ‘2’. It was an overview of two recent projects that I’ve been working on: double public goods for acid mediated […]... Read more »

  • March 2, 2015
  • 11:55 PM
  • 255 views

Short history of iterated prisoner’s dilemma tournaments

by Artem Kaznatcheev in Evolutionary Games Group

Nineteen Eighty — if I had to pick the year that computational modeling invaded evolutionary game theory then that would be it. In March, 1980 — exactly thirty-five years ago — was when Robert Axelrod, a professor of political science at University of Michigan, published the results of his first tournament for iterated prisoner’s dilemma […]... Read more »

  • February 25, 2015
  • 11:45 PM
  • 274 views

Operationalizing replicator dynamics and partitioning fitness functions

by Artem Kaznatcheev in Evolutionary Games Group

As you know, dear regular reader, I have a rather uneasy relationship with reductionism, especially when doing mathematical modeling in biology. In mathematical oncology, for example, it seems that there is a hope that through our models we can bring a more rigorous mechanistic understanding of cancer, but at the same time there is the […]... Read more »

Archetti, M., Ferraro, D.A., & Christofori, G. (2015) Heterogeneity for IGF-II production maintained by public goods dynamics in neuroendocrine pancreatic cancer. Proceedings of the National Academy of Sciences of the United States of America, 112(6), 1833-8. PMID: 25624490  

  • February 21, 2015
  • 11:55 PM
  • 253 views

Pairwise games as a special case of public goods

by Artem Kaznatcheev in Evolutionary Games Group

Usually, when we are looking at public goods games, we consider an agent interacting with a group of n other agents. In our minds, we often imagine n to be large, or sometimes even take the limit as n goes to infinity. However, this isn’t the only limit that we should consider when we are […]... Read more »

  • February 13, 2015
  • 11:00 PM
  • 291 views

Evolutionrary game theory without interactions

by Artem Kaznatcheev in Evolutionary Games Group

When I am working on evolutionary game theory, I usually treat the models I build as heuristics to guide intuitions and push the imagination. But working on something as practical as cancer, and being in a department with many physics-trained colleagues puts pressure on me to think of moving more towards insilications or abductions. Now, […]... Read more »

  • February 10, 2015
  • 11:55 PM
  • 325 views

False memories and journalism

by Artem Kaznatcheev in Evolutionary Games Group

We like to think of ourselves as a collection of our memories, and of each memory as a snapshot of an event in our lives. Sure, we all know that our minds aren’t as sturdy as our computer’s hard-drive, so these snapshots decay over time, especially the boring ones — that’s why most of us […]... Read more »

Loftus, E.F. (2003) Make-believe memories. The American Psychologist, 58(11), 867-73. PMID: 14609374  

  • February 4, 2015
  • 11:55 PM
  • 235 views

Seeing edge effects in tumour histology

by Artem Kaznatcheev in Evolutionary Games Group

Some of the hardest parts of working towards the ideal of a theorist, at least for me, are: (1) making sure that I engage with problems that can be made interesting to the new domain I enter and not just me; (2) engaging with these problems in a way and using tools that can be […]... Read more »

Kaznatcheev, A., Scott, J.G., & Basanta, D. (2015) Edge effects in game theoretic dynamics of spatially structured tumours. arXiv. info:/

  • January 28, 2015
  • 11:55 PM
  • 290 views

Space and stochasticity in evolutionary games

by Artem Kaznatcheev in Evolutionary Games Group

Two of my goals for TheEGG this year are to expand the line up of contributors and to extend the blog into a publicly accessible venue for active debate about preliminary, in-progress, and published projects; a window into the everyday challenges and miracles of research. Toward the first goal, we have new contributions from Jill […]... Read more »

Durrett, R., & Levin, S. (1994) The Importance of Being Discrete (and Spatial). Theoretical Population Biology, 46(3), 363-394. DOI: 10.1006/tpbi.1994.1032  

  • January 22, 2015
  • 12:45 PM
  • 308 views

Double public goods games and acid-mediated tumor invasion

by Artem Kaznatcheev in Evolutionary Games Group

Although I’ve spent more time thinking about pairwise games, I’ve recently expanded my horizons to more serious considerations of public-goods games. They crop up frequently when we are modeling agents at the cellular level, since interacts are often indirect through production of some sort of common extra-cellular signal. Unlike the trivial to characterize two strategy […]... Read more »

  • January 20, 2015
  • 11:55 PM
  • 276 views

Truthiness of irrelevant detail in explanations from neuroscience to mathematical models

by Artem Kaznatcheev in Evolutionary Games Group

Truthiness is the truth that comes from the gut, not books. Truthiness is preferring propositions that one wishes to be true over those known to be true. Truthiness is a wonderful commentary on the state of politics and media by a fictional character determined to be the best at feeling the news at us. Truthiness […]... Read more »

Weisberg, D.S., Keil, F.C., Goodstein, J., Rawson, E., & Gray, J.R. (2008) The seductive allure of neuroscience explanations. Journal of Cognitive Neuroscience, 20(3), 470-7. PMID: 18004955  

  • January 19, 2015
  • 11:45 PM
  • 295 views

What makes a discipline ‘mathematical’?

by Artem Kaznatcheev in Evolutionary Games Group

While walking to work on Friday, I was catching up on one of my favorite podcasts: The History of Philosophy without any Gaps. To celebrate the podcast’s 200th episode, Peter Adamson was interviewing Jill Kraye and John Marenbon on medieval philosophy. The podcasts was largely concerned with where we should define the temporal boundaries of […]... Read more »

Sylla, Edith D. (2011) Oxford Calculators. Encyclopedia of Medieval Philosophy, 903-908. DOI: 10.1007/SpringerReference_187789  

  • January 12, 2015
  • 10:30 PM
  • 300 views

Cataloging a year of blogging: the philosophical turn

by Artem Kaznatcheev in Evolutionary Games Group

Passion and motivation are strange and confusing facets of being. Many things about them feel paradoxical. For example, I really enjoy writing, categorizing, and — obviously, if you’ve read many of the introductory paragraphs on TheEGG — blabbing on far too long about myself. So you’d expect that I would have been extremely motivated to […]... Read more »

Kaznatcheev, A., Montrey, M., & Shultz, T.R. (2014) Evolving useful delusions: Subjectively rational selfishness leads to objectively irrational cooperation. Proceedings of the 36th annual conference of the Cognitive Science Society. arXiv: 1405.0041v1

  • January 6, 2015
  • 11:45 PM
  • 323 views

Cataloging a year of blogging: cancer and biology

by Artem Kaznatcheev in Evolutionary Games Group

Welcome to 111101111. Another year has come to an end, and it is time to embrace tradition and reflect on the past twelve months. In fact, I will try to do one better and start a new tradition: cataloging a year of blogging. Last year, I split up the 83 content heavy posts of 2013 […]... Read more »

Kaznatcheev, A., Scott, J.G., & Basanta, D. (2014) Edge effects in game theoretic dynamics of spatially structured tumours. arXiv. arXiv: 1307.6914v2

  • December 3, 2014
  • 10:45 PM
  • 505 views

Memes, compound strategies, and factoring the replicator equation

by Artem Kaznatcheev in Evolutionary Games Group

When you work with evolutionary game theory for a while, you end up accumulating an arsenal of cute tools and tricks. A lot of them are obvious once you’ve seen them, but you usually wouldn’t bother looking for them if you hadn’t know they existed. In particular, you become very good friends with the replicator […]... Read more »

Börgers, T., & Sarin, R. (1997) Learning through reinforcement and replicator dynamics. Journal of Economic Theory, 77(1), 1-14. DOI: 10.1006/jeth.1997.2319  

  • November 24, 2014
  • 05:15 AM
  • 466 views

Helicobacter pylori and stem cells in the gastric crypt

by Artem Kaznatcheev in Evolutionary Games Group

Last Friday, the 4th Integrated Mathematical Oncology Workshop finished here at Moffitt. The event drew a variety of internal and external participants — you can see a blurry photo of many of them above — and was structured as a competition between four teams specializing in four different domains: Microbiome, Hepatitis C, Human papillomavirus, and […]... Read more »

Houghton, J., Stoicov, C., Nomura, S., Rogers, A.B., Carlson, J., Li, H., Cai, X., Fox, J.G., Goldenring, J.R., & Wang, T.C. (2004) Gastric cancer originating from bone marrow-derived cells. Science, 306(5701), 1568-71. PMID: 15567866  

  • November 18, 2014
  • 01:15 PM
  • 342 views

From H. pylori to Spanish colonialism: the scales of cancer.

by Artem Kaznatcheev in Evolutionary Games Group

Yesterday was the first day of the 4th Integrated Mathematical Oncology Workshop here at Moffitt. This year, it is run jointly with the Center for Infection Research in Cancer and is thus focused on the interaction of infection disease and cancer. This is a topic that I have not focused much attention on — except […]... Read more »

Kodaman, N., Pazos, A., Schneider, B.G., Piazuelo, M.B., Mera, R., Sobota, R.S., Sicinschi, L.A., Shaffer, C.L., Romero-Gallo, J., de Sablet, T.... (2014) Human and Helicobacter pylori coevolution shapes the risk of gastric disease. Proceedings of the National Academy of Sciences of the United States of America, 111(4), 1455-60. PMID: 24474772  

  • November 7, 2014
  • 11:45 PM
  • 381 views

Bernstein polynomials and non-linear public goods in tumours

by Artem Kaznatcheev in Evolutionary Games Group

By analogy, or maybe homage, to standard game theory, when we discuss the payoffs of an evolutionary game, we usually tell the story of two prototype agents representing their respective strategies meeting at random and interacting. For my stories of yarn, knitting needles, and clandestine meetings in the dark of night, I even give these […]... Read more »

  • November 1, 2014
  • 11:55 PM
  • 401 views

From realism to interfaces and rationality in evolutionary games

by Artem Kaznatcheev in Evolutionary Games Group

As I was preparing some reading assignments, I realized that I don’t have a single resource available that covers the main ideas of the interface theory of perception, objective versus subjective rationality, and their relationship to evolutionary game theory. I wanted to correct this oversight and use it as opportunity to comment on the philosophy […]... Read more »

Kaznatcheev, A., Montrey, M., & Shultz, T.R. (2014) Evolving useful delusions: Subjectively rational selfishness leads to objectively irrational cooperation. Proceedings of the 36th annual conference of the cognitive science societ. arXiv: 1405.0041v1

  • October 25, 2014
  • 11:30 PM
  • 401 views

Stem cells, branching processes and stochasticity in cancer

by Artem Kaznatcheev in Evolutionary Games Group

When you were born, you probably had 270 bones in your body. Unless you’ve experienced some very drastic traumas, and assuming that you are fully grown, then you probably have 206 bones now. Much like the number and types of internal organs, we can call this question of science solved. Unfortunately, it isn’t always helpful […]... Read more »

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