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  • March 5, 2013
  • 11:47 PM
  • 840 views

Perfect match

by Jon Brock in Cracking the Enigma

I've got a new post over on the SFARI (Simons Foundation Autism Research Initiative) blog discussing the use of control groups in autism research.Control groups are an essential part of autism research, providing a benchmark against which to assess those with autism. Finding, for instance, that participants with autism score an average of 68 percent on a test is meaningless if you don’t know how people who don’t have autism do on the same test.  A control group can also b........ Read more »

Kover ST, & Atwoo AK. (2013) Establishing equivalence: methodological progress in group-matching design and analysis. American journal on intellectual and developmental disabilities, 118(1), 3-15. PMID: 23301899  

  • March 5, 2013
  • 06:27 AM
  • 1,019 views

Does watching the news make you feel more miserable than not watching it?

by Stuart Farrimond in Guru: Science Blog

That’s a really great question. Whether we watch, read, or listen to the news, I’m sure we have all had the feeling of being sick about it; be it the story itself or how it is presented. A huge proportion of our news seems to be negatively biased – but why? The answer has, in [...]... Read more »

  • March 3, 2013
  • 11:24 PM
  • 958 views

Is Living in an Urban City a Risk Factor for Bulimia Nervosa?

by Tetyana in Science of Eating Disorders

The link between urban living and mental disorders such as schizophrenia and depression has been known for quite some time (Sundquist et al., 2004). In one study, Sundquist et al found that individuals living in a densely populated area had a 68-77% higher risk of developing psychosis and 12-22% higher risk of developing depression.
The question then arises, do eating disorders follow a similar pattern? And if yes, what are some possible explanations? Certainly we know that both genetic and envi........ Read more »

VAN SON, G., VAN HOEKEN, D., BARTELDS, A., VAN FURTH, E., & HOEK, H. (2006) Urbanisation and the incidence of eating disorders. The British Journal of Psychiatry, 189(6), 562-563. DOI: 10.1192/bjp.bp.106.021378  

  • February 28, 2013
  • 04:26 PM
  • 830 views

Framing Eating Disorders As “Brain Diseases” Might Lead to More Stigma

by Tetyana in Science of Eating Disorders

Many-myself included-assume that emphasizing the biological basis of mental disorders will reduce mental health stigma. The idea is that it will place less blame and personal responsibility on the affected individual.
Still, when it comes to raising awareness and reducing stigma, we need to make sure that our assumptions hold up to the evidence, otherwise we run the risk of playing a game of broken telephone. Given that this is Eating Disorder Awareness Week in the United States, th........ Read more »

Angermeyer, M., Mnich, E., Daubmann, A., Herich, L., Wegscheider, K., Kofahl, C., & Knesebeck, O. (2013) Biogenetic explanations and public acceptance of people with eating disorders. Social Psychiatry and Psychiatric Epidemiology. DOI: 10.1007/s00127-012-0648-9  

  • February 25, 2013
  • 05:30 PM
  • 1,254 views

Rigid Food Rules in Eating Disorders: Is Perfectionism to Blame?

by Tetyana in Science of Eating Disorders

I remember cutting baby carrots into 6 pieces. Rushing home to eat because I wasn’t “allowed” to eat after 7 pm. Eating the exact portion size-no more, no less. (Oh the rules. I don’t miss them.) Rigid food rules are very common among eating disorder sufferers. These rules can be about anything: the foods you are allowed to eat, how you are allowed to eat them, the time you are allowed to eat them, and so on.
But where do they come from? Why do some indivi........ Read more »

Brown, A., Parman, K., Rudat, D., & Craighead, L. (2012) Disordered eating, perfectionism, and food rules. Eating Behaviors, 13(4), 347-353. DOI: 10.1016/j.eatbeh.2012.05.011  

  • February 22, 2013
  • 09:28 PM
  • 1,660 views

Chewing and Spitting: A Neglected Symptom in Eating Disorders?

by Shelly Fan in Science of Eating Disorders

Dear Science of Eating Disorders readers, please welcome Shelly, our newest contributor! Shelly is a PhD Candidate in Neuroscience at the University of British Columbia. You can find out more about Shelly on the ‘About Shelly‘ page. Check out her neuro(science) blog, Neurorexia and follow her on Twitter. Email shelly@scienceofeds.org to get in-touch. 
Just a note, do keep in mind that I (Tetyana) try to give as much freedom as possible to guest writers and contributors to ........ Read more »

Guarda, A., Coughlin, J., Cummings, M., Marinilli, A., Haug, N., Boucher, M., & Heinberg, L. (2004) Chewing and spitting in eating disorders and its relationship to binge eating. Eating Behaviors, 5(3), 231-239. DOI: 10.1016/j.eatbeh.2004.01.001  

  • February 20, 2013
  • 09:16 PM
  • 867 views

Lifetime Prevalence of Eating Disorders Among Eating Disorder Professionals

by Tetyana in Science of Eating Disorders

How many professionals that treat eating disorders have a personal history of struggling with an eating disorder? It is a crucial question to ask (and answer) because there are important implications for patient treatment and for the health of the afflicted professionals. It is true that many (or most?) individuals who go into mental health do so because of personal experiences-whether due to their own personal history or the experiences of a loved one-so it is useful to ask, just ho........ Read more »

BARBARICH, N. (2002) Lifetime Prevalence of Eating Disorders Among Professionals in the Field. Eating Disorders, 10(4), 305-312. DOI: 10.1080/10640260214505  

  • February 17, 2013
  • 11:45 PM
  • 750 views

Shared Genetics Between Disordered Eating and Periods (Menses)

by Tetyana in Science of Eating Disorders

Puberty at an early age increases the risk for disordered eating behaviours such as bingeing and purging (Jacobi et al., 2004; Kaltiala-Heino et al., 2001). What’s more, the hormone estradiol moderates the risk of disordered eating behaviours. More precisely, in a group of twins with low estradiol levels, differences in disordered eating are likely due to environmental factors (such as family, school, friends), but in a group of twins with high estradiol levels, the differences in dis........ Read more »

Baker JH, Thornton LM, Bulik CM, Kendler KS, & Lichtenstein P. (2012) Shared genetic effects between age at menarche and disordered eating. The Journal of Adolescent Health, 51(5), 491-6. PMID: 23084171  

  • February 14, 2013
  • 11:58 PM
  • 1,383 views

Personality Traits after Recovery from Eating Disorders: Do Anorexia and Bulimia Patients Differ?

by Tetyana in Science of Eating Disorders

When we think about eating disorders, we tend to think about eating disorder subtypes: anorexia nervosa (AN), bulimia nervosa (BN), and binge eating disorder. A lot of previous work has shown that individuals with AN and BN tend to be anxious, depressed, perfectionistic, and harm-avoidant. Patients with AN also tend to score low on novelty-seeking, impulsivity, and self-directedness, whereas patients with BN score high on novelty-seeking and impulsivity. More recently, however, some researchers ........ Read more »

Wagner, A., Barbarich-Marsteller, N., Frank, G., Bailer, U., Wonderlich, S., Crosby, R., Henry, S., Vogel, V., Plotnicov, K., McConaha, C.... (2006) Personality traits after recovery from eating disorders: Do subtypes differ?. International Journal of Eating Disorders, 39(4), 276-284. DOI: 10.1002/eat.20251  

  • February 12, 2013
  • 02:48 PM
  • 985 views

Depressed Patients Seek Primary Care Due to Pain

by Kim Kristiansen in Picture of Pain

More than half of patients with depression in primary care comes due to pain... Read more »

Kim Kristiansen, M.D. (2013) Depressed Patients Seek Primary Care Due to Pain. Picture of Pain Blog. info:/

  • February 10, 2013
  • 02:07 AM
  • 1,971 views

Bingeing and Purging Marathons: Repeated Binge/Purge Cycles in Bulimia Nervosa

by Tetyana in Science of Eating Disorders

I used to call them bingeing and purging marathons. If I binged and purged in the morning, chances were, I’d binge and purge throughout the day. The next time I’d eat, I was likely to end up–whether I wanted to or not–bingeing and purging. Not all individuals with bulimia nervosa binge and purge every day (or purge everything they eat, for that matter), but many do, and some binge and purge multiple times a day. In recovery, many people start by trying not to binge and purge before a c........ Read more »

Johnson, W., Jarrell, M., Chupurdia, K., & Williamson, D. (2010) Repeated binge/purge cycles in bulimia nervosa: Role of glucose and insulin. International Journal of Eating Disorders, 15(4), 331-341. DOI: 10.1002/eat.2260150404  

  • February 7, 2013
  • 11:59 PM
  • 2,054 views

Medical Complications of Purging in Bulimia Nervosa

by Tetyana in Science of Eating Disorders

Eating disorders are mental disorders with physical complications. Sometimes lots of them. I’ve blogged before about medical complications that are likely to come up in an emergency room setting, but that was a while ago. So I thought that today I’ll focus specifically on medical complications  that occur in bulimia nervosa as a result of purging (self-induced vomiting, laxative abuse, and diuretic abuse).
These complications are particularly important because (1) patients with ........ Read more »

Mehler, P. (2010) Medical complications of bulimia nervosa and their treatments. International Journal of Eating Disorders. DOI: 10.1002/eat.20825  

  • February 6, 2013
  • 11:49 AM
  • 1,050 views

Interferon-induced Depression: Genetics

by William Yates, M.D. in Brain Posts

Photo of a pair of green wing tealInterferon remains a key first line treatment for treatment of hepatitis C.  However, interferon has significant neuropsychiatric effects including risk for depression and even suicide in rare individuals.Some individuals with hepatitis C are unable to complete a course of interferon because of induced depression.  This makes understanding this phenomenon important to develop prevention and treatment strategies.Understanding how interferon induces depr........ Read more »

  • February 4, 2013
  • 11:56 PM
  • 1,441 views

Is Anorexia Nervosa An Anxiety Disorder?

by Tetyana in Science of Eating Disorders

Anxiety disorders (ADs) are common among patients with eating disorders. In one study of female inpatients, around 50-65% had a comorbid anxiety disorder (see my post here). Anxiety disorders in patients with anorexia nervosa (AN) typically begin before the eating disorder and often persist after weight restoration and recovery (Bulik et al., 1997; Casper, 1990). Moreover, previous twin studies have suggested that there’s a “correlation between eating disorders and certain anxiety an........ Read more »

Strober, M., Freeman, R., Lampert, C., & Diamond, J. (2007) The association of anxiety disorders and obsessive compulsive personality disorder with anorexia nervosa: Evidence from a family study with discussion of nosological and neurodevelopmental implications. International Journal of Eating Disorders, 40(S3). DOI: 10.1002/eat.20429  

  • February 4, 2013
  • 11:58 AM
  • 882 views

Oxytocin and Grandparent Attachment

by William Yates, M.D. in Brain Posts

I a previous post I summarized a review of the emerging research field of oxytocin and human attachment.This research supports a key role for oxytocin in reproduction and parental infant bonding.   The above mentioned review emphasized the important role of gender, genetic and early environment in the effect individual human variation in oxytocin response.One additionally related important research topic relates to the effect of ageing on oxytocin-related systems.  Huffmeijer and colle........ Read more »

  • February 2, 2013
  • 11:11 PM
  • 1,062 views

Over-Exercise is Associated With Suicidality in Individuals with Disordered Eating

by Tetyana in Science of Eating Disorders

Last week, I blogged about a study that examined personality traits and clinical variables associated with excessive exercise in eating disorder patients. In that study, 2 out of 5 participants engaged in excessive exercise Today, I’m going to discuss a study that suggests over-exercise in disordered eating patients is associated with suicide behaviour.
Suicide rates in eating disorder patients are high. One meta-analysis suggested that out of all eating disorder related deaths, 1 in ........ Read more »

Smith, A., Fink, E., Anestis, M., Ribeiro, J., Gordon, K., Davis, H., Keel, P., Bardone-Cone, A., Peterson, C., Klein, M.... (2012) Exercise caution: Over-exercise is associated with suicidality among individuals with disordered eating. Psychiatry Research. DOI: 10.1016/j.psychres.2012.11.004  

  • February 1, 2013
  • 11:44 AM
  • 1,093 views

Oxytocin and Human Attachment

by William Yates, M.D. in Brain Posts

In a previous post, I summarized a recent review on the neuroscience of human attachment. This review highlighted research related to the human bonding and social interactions.  Attachment ability shows significant variability in humans with insecure attachment styles contributing to risk for some mental disorders.     The neuroanatomical framework for social processing is being investigated with brain imaging techniques.Hormonal factors including the role of oxytoc........ Read more »

  • January 31, 2013
  • 12:47 PM
  • 841 views

Neuroscience of Human Attachment

by William Yates, M.D. in Brain Posts

Attachment is the ability to form human relationship bonds.  Individuals vary in their ability to develop social relationships.  The ability to form secure human relationships plays a key role in successful personal and occupational development.Attachment theory evolved over 50 years ago.  This theory proposes all humans have an innate biological mechanism that supports social engagement.  This engagement is necessary during infancy to encourage nurturance and provision of a ........ Read more »

  • January 30, 2013
  • 01:45 AM
  • 910 views

What Really Goes On Inside Pro-Ana Communities? (Maybe They Are Not So Bad After All)

by Tetyana in Science of Eating Disorders

Ambivalence is a great word to describe how many eating disorder patients feel about recovery. Many people that follow my Science of Eating Disorders tumblr run thinspo blogs. But, they follow me, and many probably follow fyoured, which offers pro-recovery advice. Many people might want to recover someday, but they feel they can’t let go of the behaviours now. They are not denying their illness, or that recovery will happen, or that it really IS a disorder, but, right now, recove........ Read more »

  • January 26, 2013
  • 11:35 PM
  • 1,010 views

Excessive Exercise in Eating Disorders

by Tetyana in Science of Eating Disorders

Excessive exercise (EE) is common among eating disorder patients. Indeed, in the study I’ll write about today, 39% of patients engaged in EE. Previous studies have tried to find psychopathological and personality correlates of EE but the results have been inconsistent. Some studies have suggested that impulsivity and addictiveness are highly correlated with EE whereas others found that anxious and depressive traits were more closely associated.
In this multi-site study, Shro........ Read more »

Shroff, H., Reba, L., Thornton, L., Tozzi, F., Klump, K., Berrettini, W., Brandt, H., Crawford, S., Crow, S., Fichter, M.... (2006) Features associated with excessive exercise in women with eating disorders. International Journal of Eating Disorders, 39(6), 454-461. DOI: 10.1002/eat.20247  

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