by Andrea in Science of Eating Disorders
If you kick around the eating disorder recovery/treatment/research community for a while, you’re bound to come across someone calling their eating disorder “Ed.” In both the popular and scholarly literature around eating disorders, this externalizing and personifying approach has come to be quite popular. At face value, it makes sense to attribute blame for what can be an extremely difficult and painful experience to something other than oneself; it might be easier to “fight fo........ Read more »
Scott, N., Hanstock, T.L., & Patterson-Kane, L. (2013) Using narrative therapy to treat eating disorder not otherwise specified. Clinical Case Studies, 12(4), 307-321. info:/10.1177/1534650113486184
by Tetyana in Science of Eating Disorders
Few people would claim to like the sound of chewing, lip smacking, or pen clicking. But while disliking these noises is commonplace, experiencing anxiety, panic and/or rage in response to them-a condition called misophonia (hatred of sound)-is not.
Well, truth be told, we don’t actually know how common it is: Searching “misophonia” in PubMed returns just 14 results. Seven were published in 2013/2014, and only three were published prior to 2010. (Searching........ Read more »
Kluckow H, Telfer J, & Abraham S. (2014) Should we screen for misophonia in patients with eating disorders? A report of three cases. International Journal of Eating Disorders. PMID: 24431300
Schröder A, Vulink N, & Denys D. (2013) Misophonia: diagnostic criteria for a new psychiatric disorder. PloS one, 8(1). PMID: 23372758
Edelstein M, Brang D, Rouw R, & Ramachandran VS. (2013) Misophonia: physiological investigations and case descriptions. Frontiers in Human Neuroscience, 296. PMID: 23805089
by Andrea in Science of Eating Disorders
How did I ever find things to write about before social media? Recently, someone on Tumblr asked whether eating disorder prevention and awareness efforts do more harm than good. In other words, can attempting to prevent eating disorders actually contribute to their development? Good question, I thought. I’ve often wondered about this myself, especially in light of some emerging studies suggesting that “healthy eating” campaigns may actually contribute to unhealthy (restrictive) behav........ Read more »
Stice E, Shaw H, & Marti CN. (2007) A meta-analytic review of eating disorder prevention programs: encouraging findings. Annual review of clinical psychology, 207-231. PMID: 17716054
by Tetyana in Science of Eating Disorders
This is the last post in my mini-series on the Mandometer® Treatment. (Links to earlier posts here: Part I, Part II, and Part III). In this post I’m going to continue examining Bergh et al.’s reasons for why eating disorders are not mental disorders (#6-10). In my last post I omitted something important: I didn’t define mental disorders, but to avoid repeating myself, please see my comment on the topic here.
Bergh et al.’s reason #6 why EDs are not mental disorder........ Read more »
Bergh C, Callmar M, Danemar S, Hölcke M, Isberg S, Leon M, Lindgren J, Lundqvist A, Niinimaa M, Olofsson B.... (2013) Effective treatment of eating disorders: Results at multiple sites. Behavioral Neuroscience, 127(6), 878-89. PMID: 24341712
by Tetyana in Science of Eating Disorders
This is Part III of my mini-series on the Mandometer® treatment. In my first post, I wrote about the history and rationale of the Mandometer® treatment. In my second post, I evaluated a recent study published by the creators of Mandometer® (Bergh et al., 2013); I wanted to see whether their data supported their claims (spoiler alert: it didn’t). In this post, I’m going to focus on the first five of Bergh et al.’s ten reasons why eating disorders are not mental disorders........ Read more »
Bergh C, Callmar M, Danemar S, Hölcke M, Isberg S, Leon M, Lindgren J, Lundqvist A, Niinimaa M, Olofsson B.... (2013) Effective treatment of eating disorders: Results at multiple sites. Behavioral Neuroscience, 127(6), 878-89. PMID: 24341712
by The Neurocritic in The Neurocritic
** This post is meant to be read in tandem with its more complimentary cousin, Electroconvulsive Therapy Impairs Memory Reconsolidation, at The Neurocomplimenter. **spECTrum 5000Q® ECT device (MECTA)Bad memories haunt a significant number of people with serious mental illnesses, such as chronic major depression and post-traumatic stress disorder (PTSD). If it were possible to undergo an experimental procedure that selectively impairs your memory for an extremely unpleasant event, would you do i........ Read more »
Kroes MC, Tendolkar I, van Wingen GA, van Waarde JA, Strange BA, & Fernández G. (2013) An electroconvulsive therapy procedure impairs reconsolidation of episodic memories in humans. Nature neuroscience. PMID: 24362759
Squire LR, Slater PC, & Chace PM. (1976) Reactivation of recent or remote memory before electroconvulsive therapy does not produce retrograde amnesia. Behavioral biology, 18(3), 335-43. PMID: 1016174
by The Neurocritic in The Neurocritic
** This post is meant to be read in tandem with its more critical cousin, How Can We Forget? at The Neurocritic. **Thymatron® System IV (Somatics, LLC)“Memories are constantly changing, each time we recall them they're physically different.”- me, July 7, 2006The precision of memory over time is a quaint idea. A large body of research shows us that memories are not fixed entities (Alberini & Ledoux, 2013). Every time a specific memory “trace” is reactivated, it enters a transiently u........ Read more »
Kroes MC, Tendolkar I, van Wingen GA, van Waarde JA, Strange BA, & Fernández G. (2013) An electroconvulsive therapy procedure impairs reconsolidation of episodic memories in humans. Nature neuroscience. PMID: 24362759
Schiller D, Monfils MH, Raio CM, Johnson DC, Ledoux JE, & Phelps EA. (2010) Preventing the return of fear in humans using reconsolidation update mechanisms. Nature, 463(7277), 49-53. PMID: 20010606
by Tetyana in Science of Eating Disorders
This is Part II of my mini-series on the Mandometer(r) treatment for eating disorders (link to Part I). In Part I, I provided some background on the Mandometer(r) treatment; in this post, I want to take an in-depth look at the recent Mandometer treatment study. My main goal is to see whether their data live up to their claims. Warning: This post may contain high levels of snark.
Their main claims? This is from the abstract:
Sounds pretty good, right? (Note the use of the word “........ Read more »
Bergh C, Callmar M, Danemar S, Hölcke M, Isberg S, Leon M, Lindgren J, Lundqvist A, Niinimaa M, Olofsson B.... (2013) Effective treatment of eating disorders: Results at multiple sites. Behavioral neuroscience, 127(6), 878-89. PMID: 24341712
by Jon Brock in Cracking the Enigma
SourceFor a while now, the prevailing view has been that the brains of people with autism are "underconnected" and that this lack of communication between different parts of the brain causes at least some of the features of autism. It's an intuitively plausible idea but it was always likely to be an over-simplification.Recently, a number of studies have pointed to the exact opposite - an increase in connectivity in autism. The emerging story is that kids with autism have "hyper connected" b........ Read more »
García Domínguez L, Stieben J, Pérez Velázquez JL, & Shanker S. (2013) The imaginary part of coherency in autism: differences in cortical functional connectivity in preschool children. PloS one, 8(10). PMID: 24098409
Supekar K, Uddin LQ, Khouzam A, Phillips J, Gaillard WD, Kenworthy LE, Yerys BE, Vaidya CJ, & Menon V. (2013) Brain hyperconnectivity in children with autism and its links to social deficits. Cell reports, 5(3), 738-47. PMID: 24210821
by Tetyana in Science of Eating Disorders
PROTIP: When selling your snake oil treatment, try NOT to make wildly outrageous efficacy claims. But if you can’t resist that temptation, try to limit your hard-to-believe, eye-roll-inducing claims to your treatment — there’s no need to go further.
In this post, I’m going to give a brief history of the Mandometer® treatment and its apparent rationale. In the next one or two posts, I will do an analysis of the most recently study by the group that claims to show r........ Read more »
Bergh C, & Södersten P. (1996) Anorexia nervosa, self-starvation and the reward of stress. Nature medicine, 2(1), 21-2. PMID: 8564826
Bergh, C., Eklund, S., Eriksson, M., Lindberg, G., & Sodersten, P. (1996) A new treatment of anorexia nervosa. . The Lancet, 611-612. DOI: 10.1016/S0140-6736(05)64824-6
Bergh, C., Brodin, U., Linberg, G., & Sodersten, P. (2002) Randomized controlled trial of a treatment for anorexia and bulimia nervosa. PNAS, 99(14), 9486-9491. DOI: 10.1073/pnas.142284799
Bergh C, Callmar M, Danemar S, Hölcke M, Isberg S, Leon M, Lindgren J, Lundqvist A, Niinimaa M, Olofsson B.... (2013) Effective treatment of eating disorders: Results at multiple sites. Behavioral neuroscience, 127(6), 878-89. PMID: 24341712
by nooffensebut in The Unsilenced Science
Dr. Kevin Beaver followed my advice and was able to show that black men with MAOA-2R are especially likely to shoot or stab. Self-righteous critics sternly wag their fingers.... Read more »
Beaver KM, Barnes JC, & Boutwell BB. (2013) The 2-Repeat Allele of the MAOA Gene Confers an Increased Risk for Shooting and Stabbing Behaviors. The Psychiatric quarterly. PMID: 24326626
Piton A, Redin C, & Mandel JL. (2013) XLID-causing mutations and associated genes challenged in light of data from large-scale human exome sequencing. American journal of human genetics, 93(2), 368-83. PMID: 23871722
Tielbeek JJ, Medland SE, Benyamin B, Byrne EM, Heath AC, Madden PA, Martin NG, Wray NR, & Verweij KJ. (2012) Unraveling the genetic etiology of adult antisocial behavior: a genome-wide association study. PloS one, 7(10). PMID: 23077488
Vimaleswaran KS, Tachmazidou I, Zhao JH, Hirschhorn JN, Dudbridge F, & Loos RJ. (2012) Candidate genes for obesity-susceptibility show enriched association within a large genome-wide association study for BMI. Human molecular genetics, 21(20), 4537-42. PMID: 22791748
by William Yates, M.D. in Brain Posts
Progress in the early diagnosis of autism and autism spectrum disorders (ASD) is being made for young children.However, there has been less attention to the diagnosis of autism in adults.Many adults with autism and ASD passed through childhood before much was known about these disorders.This means many adults with ASD may still be not be diagnosed and are not being referred for potentially beneficial services.A recent study from the Karolinska Institute in Sweden supports the validity of a new s........ Read more »
Eriksson JM, Andersen LMJ, Bejerot S. (2013) RAADS-14 Screen: validity of a screening tool for autism spectrum disorder in an adult psychiatric population. Molecular Autism. DOI: 10.1186/2040-2392-4-49
by William Yates, M.D. in Brain Posts
The relationship between football-related head injury and brain disorders is an important research topic.Case reports of chronic traumatic encephalopathy (CTE) continue to emerge among retired NFL football players.In a previous post, I have summarized a Mayo Clinic study finding limited evidence for increased brain injury in a cohort of high school football players.In another related post, I summarized research demonstrating college football players with sport-related head trauma had evidence of........ Read more »
Hazrati LN, Tartaglia MC, Diamandis P, Davis KD, Green RE, Wennberg R, Wong JC, Ezerins L, & Tator CH. (2013) Absence of chronic traumatic encephalopathy in retired football players with multiple concussions and neurological symptomatology. Frontiers in human neuroscience, 222. PMID: 23745112
by nooffensebut in The Unsilenced Science
This is a thorough review of everything stupid ever said about the warrior gene, MAOA.... Read more »
Byrd AL, & Manuck SB. (2013) MAOA, Childhood Maltreatment, and Antisocial Behavior: Meta-analysis of a Gene-Environment Interaction. Biological psychiatry. PMID: 23786983
by Andrea in Science of Eating Disorders
Studying, as I do, in a department of family relations, I have become interested in family relationships and parenting. Accordingly, I have begun to take note of interesting studies that link family dynamics and parenting with eating disorders, including studies that look at the sibling relationship (as I wrote about here), family-based treatment, and motherhood/fatherhood in the context of eating disorders.
The literature appears to have shifted, lately, from a focus on “eating-disorder ........ Read more »
Tuval-Mashiach R, Ram A, Shapiro T, Shenhav S, & Gur E. (2013) Negotiating maternal identity: mothers with eating disorders discuss their coping. Eating Disorders, 21(1), 37-52. PMID: 23241089
by William Yates, M.D. in Brain Posts
Adoption research can provide a unique perspective for understanding genetic and environmental contributions to brain disorders.In the adoption process, biological (genetic) influences occur outside the biological environment.A variety of adoption studies show genetic influences for risk of childhood and adult brain and behavior disorders. Adoptees with a biological parent with alcohol or drug abuse have higher rates of substance disorders even when raised in adoptive family environments without........ Read more »
Yoon G, Westermeyer J, Warwick M, & Kuskowski MA. (2012) Substance use disorders and adoption: findings from a national sample. PloS one, 7(11). PMID: 23166740
by William Yates, M.D. in Brain Posts
Disability in learning mathematics is a common condition affecting about 5% of the population.I have previously posted a research review on the topic of developmental mathematics disorder, also known as dyscalculia here.A recent imaging study sheds some light on some of the brain correlates of developmental mathematics disorder.Cappelleti and Price from the University College of London studied a group of eleven individuals with developmental mathematics disorder.Subjects in the study were adults........ Read more »
Cappelletti M, & Price CJ. (2013) Residual number processing in dyscalculia. NeuroImage. Clinical, 18-28. PMID: 24266008
by William Yates, M.D. in Brain Posts
In the previous two posts, I reviewed recent studies of childhood outcome following preterm birth.These posts highlighted the increased risk for childhood anxiety, ADHD and autism as well as increased risk for learning disability and cerebral palsy.Preterm birth appears related to the risk for adult brain disorders including schizophrenia.A recent study from Sweden provides some additional insight into the common risk for preterm birth to influence rates for a variety of adult brain disorders.No........ Read more »
Nosarti C, Reichenberg A, Murray RM, Cnattingius S, Lambe MP, Yin L, MacCabe J, Rifkin L, & Hultman CM. (2012) Preterm birth and psychiatric disorders in young adult life. Archives of general psychiatry, 69(6). PMID: 22660967
by William Yates, M.D. in Brain Posts
This is the second in a series of three posts examining the role of preterm birth in later child and adult brain disorders.In a previous post, I reviewed a recent study showing evidence on increased risk for anxiety disorder, ADHD and autism in preterm birth children by age 7 years of age.In this post I want to review and comment on a large French study of outcome in a cohort of very preterm children.Marrett and colleagues summarized the key elements in the design of their research:Sample: All p........ Read more »
Marret S, Marchand-Martin L, Picaud JC, Hascoët JM, Arnaud C, Rozé JC, Truffert P, Larroque B, Kaminski M, Ancel PY.... (2013) Brain injury in very preterm children and neurosensory and cognitive disabilities during childhood: the EPIPAGE cohort study. PloS one, 8(5). PMID: 23658763
by William Yates, M.D. in Brain Posts
This will be the first in a series of posts on preterm birth. Preterm birth may not seem on the surface important in brain disorders.However, an increasing body of research is showing the importance of preterm birth in later development of childhood and adult brain disorders.An important contribution to this area of research is an Australian study using structured psychiatric assessment in a series of children at age seven who had been born prematurely.The key elements of this study design inclu........ Read more »
Treyvaud K, Ure A, Doyle LW, Lee KJ, Rogers CE, Kidokoro H, Inder TE, & Anderson PJ. (2013) Psychiatric outcomes at age seven for very preterm children: rates and predictors. Journal of child psychology and psychiatry, and allied disciplines, 54(7), 772-9. PMID: 23347471
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