by Stephen Thomas in Sports Medicine Research (SMR): In the Lab & In the Field
The objective of this randomized clinical trial was to determine if immobilization following rotator cuff repair improves functional outcomes and tendon healing in humans compared to early passive motion.... Read more »
Kim YS, Chung SW, Kim JY, Ok JH, Park I, & Oh JH. (2012) Is Early Passive Motion Exercise Necessary After Arthroscopic Rotator Cuff Repair?. The American Journal of Sports Medicine. PMID: 22287641
by Joseph Zeni in Sports Medicine Research (SMR): In the Lab & In the Field
The authors in this paper evaluated the value of “prehabilitation” before knee replacement.... Read more »
Swank AM, Kachelman JB, Bibeau W, Quesada PM, Nyland J, Malkani A, & Topp RV. (2011) Prehabilitation before total knee arthroplasty increases strength and function in older adults with severe osteoarthritis. Journal of Strength and Conditioning Research, 25(2), 318-25. PMID: 21217530
by Kris Fayock in Sports Medicine Research (SMR): In the Lab & In the Field
Bronfort et al tested the effectiveness of spinal manipulation therapy (SMT), medication, and home exercise with advice (HEA) for acute and sub-acute neck pain.... Read more »
Bronfort G, Evans R, Anderson AV, Svendsen KH, Bracha Y, & Grimm RH. (2012) Spinal manipulation, medication, or home exercise with advice for acute and subacute neck pain: a randomized trial. Annals of Internal Medicine, 156(1 Pt 1), 1-10. PMID: 22213489
by William Yates, M.D. in Brain Posts
Three previous posts examined the clinical neuroscience disorder antisocial personality disorder (ASPD). This condition results in high societal costs for crime and incarceration for individuals with ASPD.ASPD appears to have significant genetic contributions and brain imaging studies show abnormal brain maturational patterns in the premotor cortex area as well as impaired processing of facial emotional expression.Antisocial personality is an early age of onset disorder with conduct disord........ Read more »
Drugli MB, Larsson B, Fossum S, & Mørch WT. (2010) Five- to six-year outcome and its prediction for children with ODD/CD treated with parent training. Journal of child psychology and psychiatry, and allied disciplines, 51(5), 559-66. PMID: 20015193
by William Yates, M.D. in Brain Posts
This is the second in a series of posts looking at recent imaging findings in antisocial personality. In the first post, I reviewed an fMRI study that found deficits in connectivity maturation involving the premotor cortex in a sample of incarcerated juveniles.In this post, I will review a study looking a emotional face processing. Accurately assessing the emotions of others and adjusting ones own behavior is a key component to social development and appropriate social behavior.Indiv........ Read more »
Passamonti L, Fairchild G, Goodyer IM, Hurford G, Hagan CC, Rowe JB, & Calder AJ. (2010) Neural abnormalities in early-onset and adolescence-onset conduct disorder. Archives of general psychiatry, 67(7), 729-38. PMID: 20603454
by William Yates, M.D. in Brain Posts
Antisocial personality disorder (ASPD) is linked to a variety of emotional and behavioral abnormalities with significant public health implications.Key components of antisocial personality disorder include irritability with anger dysregulation. Individuals with ASPD are quick tempered with anger outbursts commonly leading to physical or emotional aggressiveness towards others.The emotional and behavioral abnormalities in ASPD may provide a model for studying specific brain regions controll........ Read more »
Shannon BJ, Raichle ME, Snyder AZ, Fair DA, Mills KL, Zhang D, Bache K, Calhoun VD, Nigg JT, Nagel BJ.... (2011) Premotor functional connectivity predicts impulsivity in juvenile offenders. Proceedings of the National Academy of Sciences of the United States of America, 108(27), 11241-5. PMID: 21709236
by William Yates, M.D. in Brain Posts
Twin studies provide a valuable method to explore the genetic and environmental contributions to a variety of clinical neuroscience disorders.Twin studies use a method where identical twins (monozygotic) sharing 100% of their genes are compared to non-identical twins (dizygotic) who share 50% of their genes.Disorders that are entirely environmental would be found at the same rates in non-identical twins and indentical twins. Disorders with a strong genetic contribution would be more likely........ Read more »
Kendler KS, Aggen SH, & Patrick CJ. (2012) A Multivariate Twin Study of the DSM-IV Criteria for Antisocial Personality Disorder. Biological psychiatry, 71(3), 247-53. PMID: 21762879
by DJ Busby in Astronasty
This discovery, in a nutshell, can be found in the last sentence of the abstract:
"Opioids thus not only temporarily dampen pain but may also erase a spinal memory trace of pain."... Read more »
Drdla-Schutting, R., Benrath, J., Wunderbaldinger, G., & Sandkuhler, J. (2012) Erasure of a Spinal Memory Trace of Pain by a Brief, High-Dose Opioid Administration. Science, 335(6065), 235-238. DOI: 10.1126/science.1211726
by Mark Rice in Sports Medicine Research (SMR): In the Lab & In the Field
Swanik et al. investigated muscle coactivation levels and coactivation patterns of the subscapularis, infraspinatus, and teres minor throughout the range of motion (ROM) of 4 commonly utilized therapeutic exercises.... Read more »
Swanik KA, Huxel Bliven K, & Swanik CB. (2011) Rotator-cuff muscle-recruitment strategies during shoulder rehabilitation exercises. Journal of Sport Rehabilitation, 20(4), 471-86. PMID: 22012500
by Hallie Labrador in Sports Medicine Research (SMR): In the Lab & In the Field
The purpose of this follow-up trial was to revisit the original subjects of a randomized controlled trial studying the impact of a training program on adductor-related groin pain and test whether the effects were still statistically significant 8 to 12 years later.... Read more »
Hölmich P, Nyvold P, & Larsen K. (2011) Continued significant effect of physical training as treatment for overuse injury: 8- to 12-year outcome of a randomized clinical trial. The American Journal of Sports Medicine, 39(11), 2447-51. PMID: 21813441
by William Yates, M.D. in Brain Posts
Cognitive Behavior Therapy or (CBT) is a form of psychotherapy originally developed for the treatment of major depression. Modifications of CBT for a variety of other neuropsychiatric disorders quickly emerged and now the demand for CBT exceeds the supply of trained therapists. Efforts to extend the benefits seen with CBT now includes telephone and internet-based methods. CBT hold promise in management of pain from a variety of medical conditions. This promise requires the deve........ Read more »
McBeth, J., Prescott, G., Scotland, G., Lovell, K., Keeley, P., Hannaford, P., McNamee, P., Symmons, D., Woby, S., Gkazinou, C.... (2011) Cognitive Behavior Therapy, Exercise, or Both for Treating Chronic Widespread Pain. Archives of Internal Medicine. DOI: 10.1001/archinternmed.2011.555
by Jeffrey B. Driban in Sports Medicine Research (SMR): In the Lab & In the Field
While several articles have reported associations between hip strength/kinematics and knee pain, including studies that suggest hip strengthening may improve knee pain (see Related Posts below), few have been randomized controlled trials assessing the benefits of isolated hip strengthening on patellofemoral pain. Recently, two randomized controlled trials assessing hip strengthening among females with patellofemoral pain have been published in JOSPT. ... Read more »
Dolak KL, Silkman C, Medina McKeon J, Hosey RG, Lattermann C, & Uhl TL. (2011) Hip strengthening prior to functional exercises reduces pain sooner than quadriceps strengthening in females with patellofemoral pain syndrome: a randomized clinical trial. The Journal of Orthopaedic and Sports Physical Therapy, 41(8), 560-70. PMID: 21654093
by Stuart Farrimond in Dr Stu's Science Blog
As anyone who’s spent time in a hospital ward will know, dementia is a big problem. The elderly with memory problems occupy a disproportionate number of hospital beds. Often admitted for a simple illness, they represent a forgotten populace left in limbo. No longer able to fully care for themselves yet not needing full-time care; … Continue reading »... Read more »
Orpwood, R., Gibbs, C., Adlam, T., Faulkner, R., & Meegahawatte, D. (2005) The design of smart homes for people with dementia—user-interface aspects. Universal Access in the Information Society, 4(2), 156-164. DOI: 10.1007/s10209-005-0120-7
by Kris Fayock in Sports Medicine Research (SMR): In the Lab & In the Field
It is important for both athletes and non-athletes to have adequate range of motion (ROM) in their muscle-joint complexes. Long-standing beliefs of how static stretching and resistance training affect strength and flexibility are now being challenged by recent research. The purpose of this study was to determine how full-range resistance training affected flexibility and strength compared to static-stretching of the same muscle-joint complexes in untrained adults. ... Read more »
Morton SK, Whitehead JR, Brinkert RH, & Caine DJ. (2011) Resistance Training vs. Static Stretching: Effects on Flexibility and Strength. Journal of Strength and Conditioning Research. PMID: 21969080
by Pranab Chatterjee in Scepticemia
Happy Pumpkin Day folks, and to celebrate this day of weird encounters, I am going to reel off a list of the commonest peeves I have experienced in the past couple of years I have been doing Medicine. There are obvious gaps in the stories, and many are not even unique to me, but I [...]... Read more »
Moseley, J., O'Malley, K., Petersen, N., Menke, T., Brody, B., Kuykendall, D., Hollingsworth, J., Ashton, C., & Wray, N. (2002) A Controlled Trial of Arthroscopic Surgery for Osteoarthritis of the Knee. New England Journal of Medicine, 347(2), 81-88. DOI: 10.1056/NEJMoa013259
Well, well dysphagia. Its been a while since you and I have gotten together for a little research. Its about time too, since my last post on the topic was several months ago. Time to snap out of this little funk and get back to some good ole nerdy writing.
I came across a nice study by some folks out in Colorado looking at dysphagia risk factors for critically ill patients, and the link between dysphagia and outcomes following critical illness. We know there seems to be a link between intubat........ Read more »
Macht M, Wimbish T, Clark BJ, Benson AB, Burnham EL, Williams A, & Moss M. (2011) Post-extubation dysphagia is persistent and associated with poor outcomes in survivors of critical illness. Critical care (London, England), 15(5). PMID: 21958475
by Krystal D'Costa in Anthropology in Practice
Excerpts from the Personal Journal of Krystal D’Costa [i] Tuesday: I fell. Again. This time it was while getting out of the car. I’m not sure how I managed it. I got my foot caught on the door jamb and tumbled forward. I hit my shin—hard—against the door jamb and I think I tweaked my [...]
... Read more »
Brown JE,, Chatterjee N,, Younger J,, & Mackey S. (2011) Towards a physiology-based measure of pain: patterns of human brain activity distinguish painful from non-painful thermal stimulation. PLoS one, 6(9). PMID: 21931652
Pia Haudrup Christensen. (1999) "It Hurts": Children's Cultural Learning About Everyday Illness. Stichting Ethnofoor, 12(1), 39-52. info:/
by William Yates, M.D. in Brain Posts
Lithium carbonate serves as a primary treatment option in the treatment of mania and bipolar affective disorder. An elemental metal, lithium has atomic number 3 in the periodic table of elements.The mechanism of action for lithium carbonate in bipolar disorder is unclear. Some of the proposed mechanisms for lithium in the central nervous system include:alteration of the neurotransmitter glutamate (affected by other drugs linked to therapeutic effect in bipolar disorder, i.e. sodium v........ Read more »
Yu F, Wang Z, Tchantchou F, Chiu CT, Zhang Y, & Chuang DM. (2011) Lithium ameliorates neurodegeneration, suppresses neuroinflammation, and improves behavioral performance in a mouse model of traumatic brain injury. Journal of neurotrauma. PMID: 21895523
by William Yates, M.D. in Brain Posts
Tinnitus, or persistent ear ringing, has no definitive treatment. I had recently posted a summary of the status of this disorder based on a research review.Since that post, a small but important placebo-controlled clinical trial examined the effect of melatonin on a group of subjects with tinnitus.Here are the key elements of the study design from this clinical trial:Subjects: Chronic tinnitus of at least 6 months duration as primary complaint (subjects ranged in age from 34 to 86)Clinical........ Read more »
Hurtuk A, Dome C, Holloman CH, Wolfe K, Welling DB, Dodson EE, & Jacob A. (2011) Melatonin: can it stop the ringing?. The Annals of otology, rhinology, and laryngology, 120(7), 433-40. PMID: 21859051
by William Yates, M.D. in Brain Posts
Sunset in Santa Fe, New MexicoMajor depression appears linked to risk for coronary artery disease and an adverse outcome following myocardial infarction. The mechanism for this association is unclear.One proposed mechanism relates to systemic markers of inflammation. Elevated serum blood levels of inflammatory markers such as interleukin-6 and C-reactive protein are risk factors for heart disease. Some research point to higher inflammatory markers levels in samples of individua........ Read more »
Duivis, H., de Jonge, P., Penninx, B., Na, B., Cohen, B., & Whooley, M. (2011) Depressive Symptoms, Health Behaviors, and Subsequent Inflammation in Patients With Coronary Heart Disease: Prospective Findings From the Heart and Soul Study. American Journal of Psychiatry, 168(9), 913-920. DOI: 10.1176/appi.ajp.2011.10081163
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