by Nsikan Akpan in That's Basic Science
In blind individuals, neurons from the 'dormant' visual cortex are enslaved by the auditory cortex...... Read more »
Collignon O, Vandewalle G, Voss P, Albouy G, Charbonneau G, Lassonde M, & Lepore F. (2011) Functional specialization for auditory-spatial processing in the occipital cortex of congenitally blind humans. Proceedings of the National Academy of Sciences of the United States of America, 108(11), 4435-40. PMID: 21368198
Collignon, O., Vandewalle, G., Voss, P., Albouy, G., Charbonneau, G., Lassonde, M., & Lepore, F. (2011) Functional specialization for auditory-spatial processing in the occipital cortex of congenitally blind humans. Proceedings of the National Academy of Sciences, 108(11), 4435-4440. DOI: 10.1073/pnas.1013928108
Amedi A, Stern WM, Camprodon JA, Bermpohl F, Merabet L, Rotman S, Hemond C, Meijer P, & Pascual-Leone A. (2007) Shape conveyed by visual-to-auditory sensory substitution activates the lateral occipital complex. Nature neuroscience, 10(6), 687-9. PMID: 17515898
An important component of any rehabilitation regime, whether it be for speech pathology or another allied health profession, is the ability of an intervention to affect cerebral plasticity. Generally speaking, cerebral plasticity is the ability of the brain to be co-opted for new uses. In the case of brain damage, it could be that the damaged area regains some of its prior function, or an entirely different area of the brain changes to accomodate the lost funtion of the damaged area. Cerebral pl........ Read more »
Clark, H. (2003) Neuromuscular Treatments for Speech and Swallowing: A Tutorial. American Journal of Speech-Language Pathology, 12(4), 400-415. DOI: 10.1044/1058-0360(2003/086)
Fraser, C., Power, M., Hamdy, S., Rothwell, J., Hobday, D., Hollander, I., Tyrell, P., Hobson, A., Williams, S., & Thompson, D. (2002) Driving Plasticity in Human Adult Motor Cortex Is Associated with Improved Motor Function after Brain Injury. Neuron, 34(5), 831-840. DOI: 10.1016/S0896-6273(02)00705-5
Hamdy S, Rothwell JC, Aziz Q, Singh KD, & Thompson DG. (1998) Long-term reorganization of human motor cortex driven by short-term sensory stimulation. Nature neuroscience, 1(1), 64-8. PMID: 10195111
HAMDY, S., ROTHWELL, J., AZIZ, Q., & THOMPSON, D. (2000) Organization and reorganization of human swallowing motor cortex: implications for recovery after stroke*. Clinical Science, 99(2), 151. DOI: 10.1042/CS19990300
Power, M. (2003) Changes in pharyngeal corticobulbar excitability and swallowing behavior after oral stimulation. AJP: Gastrointestinal and Liver Physiology, 286(1), 45-50. DOI: 10.1152/ajpgi.00114.2003
Robbins J, Butler SG, Daniels SK, Diez Gross R, Langmore S, Lazarus CL, Martin-Harris B, McCabe D, Musson N, & Rosenbek J. (2008) Swallowing and dysphagia rehabilitation: translating principles of neural plasticity into clinically oriented evidence. Journal of speech, language, and hearing research : JSLHR, 51(1). PMID: 18230851
by William Yates, M.D. in Brain Posts
The presence of mild cognitive impairment (MCI) in elderly individuals is often a clinical challenge of uncertainly prognostic value. Defined as cognitive function below the normal range but insufficient for a diagnosis of dementia, MCI is receiving increased research attention. This week in the New England Journal of Medicine, Dr. Ronald Petersen, a neurologist from the Mayo Clinic in Rochester, Minnesota highlighted what is known about MCI. His review summarizes some of........ Read more »
Petersen, RC. (2011) Mild Cognitive Impairment. New Engl J Med, 2227-2234. info:/
by Bronwyn Thompson in Healthskills: Skills for Healthy Living
Cognitive behavioural approaches for pain management are not exactly the same as cognitive behavioural therapy for mental health problems. While there are some underlying concepts that are the same, cognitive behavioural approaches for pain management include a wider range of strategies, and are far less readily defined than the very structured approach used in mental … Read more... Read more »
Bailey, K. M., Carleton, R., Vlaeyen, J. W., & Asmundson, G. J. (2010) Treatments addressing pain-related fear and anxiety in patients with chronic musculoskeletal pain: A preliminary review. . Cognitive Behaviour Therapy, 39(1). DOI: 10.1080/16506070902980711
Swallowing is a complex maneuver designed to pass food and drink safely into the stomach without the bolus taking an abberrant path into the adjacent airway, lest you choke while eating pretzel while watching football. Fortunately for most of us, several safety mechanisms exist to prevent pretzels, and other detritus, from entering the airway, but given the open proximity of our airway to our food pathway, the risk of aspiration, albeit a subtle one, ........ Read more »
Wheeler Hegland K, Huber JE, Pitts T, Davenport PW, & Sapienza CM. (2011) Lung volume measured during sequential swallowing in healthy young adults. Journal of speech, language, and hearing research : JSLHR, 54(3), 777-86. PMID: 20966381
by William Yates, M.D. in Brain Posts
Smoking and nicotine dependence increase rates for heart disease in the general population. Among those with heart disease, continued smoking increases mortality rates. Targeting smoking cessation efforts at those with heart disease (secondary prevention)is an important clinical challenge. Most of the research data related to drugs for smoking cessation come from subjects recruited from the general population. Both bupropion (Zyban)and varenicline (Chantix)are FDA-approved drugs for smokin........ Read more »
Planer, D., Lev, I., Elitzur, Y., Sharon, N., Ouzan, E., Pugatsch, T., Chasid, M., Rom, M., & Lotan, C. (2011) Bupropion for Smoking Cessation in Patients With Acute Coronary Syndrome. Archives of Internal Medicine. DOI: 10.1001/archinternmed.2011.72
by Bronwyn Thompson in Healthskills: Skills for Healthy Living
I’m taking a tiny detour from the world of catastrophising - but only a tiny one because catastrophising is associated with greater levels of pain behaviour, and of course, discussion about pain behaviour is how I came to begin my exploration of catastrophising anyway! There have been several schools of thought, or models of treatment, … Read more... Read more »
Martel, M., Thibault, P., & Sullivan, M. (2010) The persistence of pain behaviors in patients with chronic back pain is independent of pain and psychological factors. Pain, 151(2), 330-336. DOI: 10.1016/j.pain.2010.07.004
by William Yates, M.D. in Brain Posts
Tinnitus is a common neurological condition affecting up to 10% or more of elderly individuals. Variable it severity, in it's most serious form it can be disabling and quite distressful. Due to the chronic nature of the disorder, many patients with tinnitus develop depression. Suicide rates have been estimated to be increased in those with tinnitus-related. Althought the exact cause is unknown for tinnitus, abnormalities in spontaneous neural activity in the auditory brai........ Read more »
Piccirillo JF, Garcia KS, Nicklaus J, Pierce K, Burton H, Vlassenko AG, Mintun M, Duddy D, Kallogjeri D, & Spitznagel EL Jr. (2011) Low-frequency repetitive transcranial magnetic stimulation to the temporoparietal junction for tinnitus. Archives of otolaryngology--head , 137(3), 221-8. PMID: 21422304
Parazzini M, Del Bo L, Jastreboff M, Tognola G, & Ravazzani P. (2011) Open ear hearing aids in tinnitus therapy: An efficacy comparison with sound generators. International journal of audiology. PMID: 21595527
by Nsikan Akpan in That's Basic Science
How a man survived for 90 minutes without a pulse.... Read more »
White RD, Goodman BW, & Svoboda MA. (2011) Neurologic Recovery Following Prolonged Out-of-Hospital Cardiac Arrest With Resuscitation Guided by Continuous Capnography. Mayo Clinic proceedings. Mayo Clinic. PMID: 21508320
Eisenberg MS. (2002) Leonard Cobb and Medic One. Resuscitation, 54(1), 5-9. PMID: 12104102
A look at an article exploring barriers to speech pathology and audiology services for the LGBT community, and how this article is used by another blogger to deride both the LGBT community and the professional organization of speech pathologists and audiologists. ... Read more »
Kelly, R., & Robinson, G. (2011) Disclosure of Membership in the Lesbian, Gay, Bisexual, and Transgender Community by Individuals With Communication Impairments: A Preliminary Web-Based Survey. American Journal of Speech-Language Pathology, 20(2), 86-94. DOI: 10.1044/1058-0360(2011/10-0060)
Kelly RJ, & Robinson GC. (2011) Disclosure of membership in the lesbian, gay, bisexual, and transgender community by individuals with communication impairments: a preliminary web-based survey. American journal of speech-language pathology / American Speech-Language-Hearing Association, 20(2), 86-94. PMID: 21393619
by Hayzell in Possibilism.org
Part of coping with pain or health difficulties includes having a self-care regimen that does your body and mind good. For me, I’ve always found that being out in nature has a way of making me feel restored. This is more than just a personal opinion: research shows that nature helps us feel better.... Read more »
Kjellgren, A., & Buhrkall, H. (2010) A comparison of the restorative effect of a natural environment with that of a simulated natural environment. Journal of Environmental Psychology, 30(4), 464-472. DOI: 10.1016/j.jenvp.2010.01.011
Mayer, F., Frantz, C., Bruehlman-Senecal, E., & Dolliver, K. (2009) Why Is Nature Beneficial?. Environment and Behavior, 41(5), 607-643. DOI: 10.1177/0013916508319745
Ryan, R., Weinstein, N., Bernstein, J., Brown, K., Mistretta, L., & Gagné, M. (2010) Vitalizing effects of being outdoors and in nature. Journal of Environmental Psychology, 159-168. DOI: 10.1016/j.jenvp.2009.10.009
van den Berg, A., Maas, J., Verheij, R., & Groenewegen, P. (2010) Green space as a buffer between stressful life events and health. Social Science , 70(8), 1203-1210. DOI: 10.1016/j.socscimed.2010.01.002
by Arya M. Sharma in Dr. Sharma's Obesity Notes
Osteoarthritis is one of the most disabling and painful conditions attributable (in part) to excess weight. Once established, osteoarthritis significantly reduces quality of life and mobility, often precipitating further weight gain and posing an important barrier to weight management.
A panel of experts (The Ottawa Panel) has now released a comprehensive set of evidence-based clinical practice [...]... Read more »
Brosseau L, Wells GA, Tugwell P, Egan M, Dubouloz CJ, Casimiro L, Bugnariu N, Welch VA, De Angelis G, Francoeur L.... (2011) Ottawa Panel Evidence-Based Clinical Practice Guidelines for the Management of Osteoarthritis in Adults Who Are Obese or Overweight. Physical therapy. PMID: 21493746
by Travis Saunders, MSc, CEP in Obesity Panacea
Image from Gamebike.com
Active gaming (aka exer-gaming) is the term used for video games that involve some level of physical activity. I’ve discussed active gaming on Obesity Panacea in the past, and while I don’t doubt that it can be an effective tool for promoting physical activity in certain specific situations (eg as a form of physiotherapy), I remain skeptical about it’s ability to increase physical activity levels for the vast majority of children.
Unfortunately for act........ Read more »
Adamo KB, Rutherford JA, & Goldfield GS. (2010) Effects of interactive video game cycling on overweight and obese adolescent health. Applied physiology, nutrition, and metabolism , 35(6), 805-15. PMID: 21164552
by Arya M. Sharma in Dr. Sharma's Obesity Notes
Readers may recall previous posts on the relationship between obesity and fibromyalgia, a chronic condition characterised by widespread pain, muscle tenderness, and decreased pain threshold to pressure and other stimuli.
Ursini and colleagues from Cantazaro, Italy, review the possible relationship between these two entities in a paper just published in Rheumatology International.
The authors review the epidemiological [...]... Read more »
Ursini F, Naty S, & Grembiale RD. (2011) Fibromyalgia and obesity: the hidden link. Rheumatology international. PMID: 21476098
by Hayzell in Possibilism.org
“Why don’t you just ask me to open it?” During the early days of my injury, this was something I hated to hear whenever I needed a bottle, jar, or even a heavy door opened. Asking for help felt like I’d be a bother and I was letting my pain win—as if I was [...]
... Read more »
Bohns, V., & Flynn, F. (2010) “Why didn’t you just ask?” Underestimating the discomfort of help-seeking. Journal of Experimental Social Psychology, 46(2), 402-409. DOI: 10.1016/j.jesp.2009.12.015
Caruso, E., Epley, N., & Bazerman, M. (2006) The costs and benefits of undoing egocentric responsibility assessments in groups. Journal of Personality and Social Psychology, 91(5), 857-871. DOI: 10.1037/0022-3514.91.5.857
Epley N, Keysar B, Van Boven L, & Gilovich T. (2004) Perspective taking as egocentric anchoring and adjustment. Journal of personality and social psychology, 87(3), 327-39. PMID: 15382983
Flynn FJ, & Lake VK. (2008) If you need help, just ask: underestimating compliance with direct requests for help. Journal of personality and social psychology, 95(1), 128-43. PMID: 18605856
Van Boven, L., Loewenstein, G., & Dunning, D. (2005) The illusion of courage in social predictions: Underestimating the impact of fear of embarrassment on other people. Organizational Behavior and Human Decision Processes, 96(2), 130-141. DOI: 10.1016/j.obhdp.2004.12.001
by Brian McMichael, M.D. in Pallimed: a Hospice & Palliative Medicine Blog
The lead research article in the current issue of the American Journal of Physical Medicine and Rehabilitation is Inpatient Rehabilitation Improved Functional Status in Asthenic Patients with Solid and Hematologic Malignancies. It was written by a team from the Department of Palliative Care and Rehabilitation Medicine and the Department of Biostatistics at the University of Texas, MD Anderson Cancer Center. This study sought to compare functional outcomes in asthenic patients with hematologic ........ Read more »
Guo, Y., Shin, K., Hainley, S., Bruera, E., & Palmer, J. (2011) Inpatient Rehabilitation Improved Functional Status in Asthenic Patients with Solid and Hematologic Malignancies. American Journal of Physical Medicine , 90(4), 265-271. DOI: 10.1097/PHM.0b013e3182063ba6
by Arya M. Sharma in Dr. Sharma's Obesity Notes
Seems like this is injury week on these pages.
After blogging about injury patterns in obese US high-school athletes on Monday, today’s article is some Canadian data just published by Warsh and colleagues from Queen’s University, Kingston, Ontario, in the International Journal of Injury Control and Safety Promotion, looking at whether overweight and obese kids take [...]... Read more »
Warsh J, Janssen I, & Pickett W. (2011) Do overweight and obese youth take longer to recover from injury?. International journal of injury control and safety promotion, 1-7. PMID: 21424972
by Pieter Droppert in Biotech Strategy Blog
Taxanes are a class of drug that are used in breast, lung and ovarian cancer chemotherapy to disrupt the function of microtubules that are essential to cell division. They include paclitaxel (Taxol®) and docetaxel (Taxotere®). Paclitaxel is also used to … Continue reading →... Read more »
Hellal, F., Hurtado, A., Ruschel, J., Flynn, K., Laskowski, C., Umlauf, M., Kapitein, L., Strikis, D., Lemmon, V., Bixby, J.... (2011) Microtubule Stabilization Reduces Scarring and Causes Axon Regeneration After Spinal Cord Injury. Science, 331(6019), 928-931. DOI: 10.1126/science.1201148
by Nsikan Akpan in That's Basic Science
The peculiar metabolic traits of bear hibernation... Read more »
Tøien Ø, Blake J, Edgar DM, Grahn DA, Heller HC, & Barnes BM. (2011) Hibernation in black bears: independence of metabolic suppression from body temperature. Science (New York, N.Y.), 331(6019), 906-9. PMID: 21330544
by perishedcore in Changing Heart and Mind
Huh. Definitely not from a person with osteoarthritis (OA): Perhaps the most important change in OA over the past 60 years has been in attitudes rather than knowledge. OA has changed from being a boring, degenerative form of joint pathology, for which nothing could be done, to an exciting clinical disorder of the joints that [...]... Read more »
Paul Dieppe. (2011) Developments in osteoarthritis. Rheumatology . , 50(2), 245-247. info:/doi: 10.1093/rheumatology/keq373
Brandt KD, Dieppe P, & Radin EL. (2008) Etiopathogenesis of osteoarthritis. Rheumatic diseases clinics of North America, 34(3), 531-59. PMID: 18687271
Roman-Blas, J., Castañeda, S., Largo, R., & Herrero-Beaumont, G. (2009) Osteoarthritis associated with estrogen deficiency. Arthritis Research , 11(5), 241. DOI: 10.1186/ar2791
Sutton S, Clutterbuck A, Harris P, Gent T, Freeman S, Foster N, Barrett-Jolley R, & Mobasheri A. (2009) The contribution of the synovium, synovial derived inflammatory cytokines and neuropeptides to the pathogenesis of osteoarthritis. Veterinary journal (London, England : 1997), 179(1), 10-24. PMID: 17911037
Darlington LG, & Stone TW. (2001) Antioxidants and fatty acids in the amelioration of rheumatoid arthritis and related disorders. The British journal of nutrition, 85(3), 251-69. PMID: 11299072
Do you write about peer-reviewed research in your blog? Use ResearchBlogging.org to make it easy for your readers — and others from around the world — to find your serious posts about academic research.
If you don't have a blog, you can still use our site to learn about fascinating developments in cutting-edge research from around the world.

Research Blogging is powered by SMG Technology.
To learn more, visit seedmediagroup.com.