November 8, 2016
02:57 AM
103 views

"A Putative Blood-Based Biomarker for Autism Spectrum Disorder-Associated Ileocolitis"

Contrary to Murphy's Law - 'never repeat a successful experiment' - replication or reproducibility is a cornerstone of good science. Today, I'm blogging about a piece of research that aimed to do just that as per the findings reported by Stephen Walker and colleagues [1] (open-access).The title of this post has been borrowed from the title of the Walker paper to illustrate how moving on from the quite widely known 'fact' that functional gastrointestinal (GI) symptoms are over-represented wh........ Read more »

Walker SJ, Beavers DP, Fortunato J, & Krigsman A. (2016) A Putative Blood-Based Biomarker for Autism Spectrum Disorder-Associated Ileocolitis. Scientific reports, 35820. PMID: 27767057

November 7, 2016
01:57 PM
111 views

Neuroteratogenic Viruses: ZIKV, the placenta and IUGR

by thelonevirologist in Virology Tidbits

In humans, the most common infectious neuroteratogenic agents are summarised by the mnemonic “TORCH(S)” (Toxoplasmosis, Others, Rubella, (Human) Cytomegalovirus, Herpes Simplex, Syphilis) with ZIKV either classified as “Others” or by expanding the mnemonic to TORCHSZ and indeed health authorities in affected countries regularly test cases of microcephaly suspected to be associated with neurological infections not only for ZIKV but also for the presence of TORCH(S). Microc........ Read more »

Yockey LJ, Varela L, Rakib T, Khoury-Hanold W, Fink SL, Stutz B, Szigeti-Buck K, Van den Pol A, Lindenbach BD, Horvath TL.... (2016) Vaginal Exposure to Zika Virus during Pregnancy Leads to Fetal Brain Infection. Cell, 166(5), 1247-12560000. PMID: 27565347

Bayless NL, Greenberg RS, Swigut T, Wysocka J, & Blish CA. (2016) Zika Virus Infection Induces Cranial Neural Crest Cells to Produce Cytokines at Levels Detrimental for Neurogenesis. Cell host , 20(4), 423-428. PMID: 27693308

El Costa H, Gouilly J, Mansuy JM, Chen Q, Levy C, Cartron G, Veas F, Al-Daccak R, Izopet J, & Jabrane-Ferrat N. (2016) ZIKA virus reveals broad tissue and cell tropism during the first trimester of pregnancy. Scientific reports, 35296. PMID: 27759009

Tabata T, Petitt M, Puerta-Guardo H, Michlmayr D, Wang C, Fang-Hoover J, Harris E, & Pereira L. (2016) Zika Virus Targets Different Primary Human Placental Cells, Suggesting Two Routes for Vertical Transmission. Cell host , 20(2), 155-66. PMID: 27443522

Quicke KM, Bowen JR, Johnson EL, McDonald CE, Ma H, O'Neal JT, Rajakumar A, Wrammert J, Rimawi BH, Pulendran B.... (2016) Zika Virus Infects Human Placental Macrophages. Cell host , 20(1), 83-90. PMID: 27247001

Bayer A, Lennemann NJ, Ouyang Y, Bramley JC, Morosky S, Marques ET Jr, Cherry S, Sadovsky Y, & Coyne CB. (2016) Type III Interferons Produced by Human Placental Trophoblasts Confer Protection against Zika Virus Infection. Cell host , 19(5), 705-12. PMID: 27066743

Ning F, Liu H, & Lash GE. (2016) The Role of Decidual Macrophages During Normal and Pathological Pregnancy. American journal of reproductive immunology (New York, N.Y. : 1989), 75(3), 298-309. PMID: 26750089

Lash GE, Pitman H, Morgan HL, Innes BA, Agwu CN, & Bulmer JN. (2016) Decidual macrophages: key regulators of vascular remodeling in human pregnancy. Journal of leukocyte biology, 100(2), 315-25. PMID: 26819320

Salamonsen LA, Hannan NJ, & Dimitriadis E. (2007) Cytokines and chemokines during human embryo implantation: roles in implantation and early placentation. Seminars in reproductive medicine, 25(6), 437-44. PMID: 17960528

Olagnier D, Amatore D, Castiello L, Ferrari M, Palermo E, Diamond MS, Palamara AT, & Hiscott J. (2016) Dengue Virus Immunopathogenesis: Lessons Applicable to the Emergence of Zika Virus. Journal of molecular biology, 428(17), 3429-48. PMID: 27130436

November 7, 2016
03:13 AM
109 views

8.6% of children with autism have epilepsy?

by Paul Whiteley in Questioning Answers

"Epilepsy was reported to co-occur in 8.6 % of ASD [autism spectrum disorder] cases."That was the headline conclusion reported by Shiny Thomas and colleagues [1] as they drew on data from "the most recent U.S. National Survey of Children's Health, 2011-2012" to add to the extensive literature looking at how common epilepsy is when it comes to autism.Including some 1600 children/young adults diagnosed with autism - equivalent to a prevalence of 1.8% of the entire 85,000-strong co........ Read more »

Thomas S, Hovinga ME, Rai D, & Lee BK. (2016) Brief Report: Prevalence of Co-occurring Epilepsy and Autism Spectrum Disorder: The U.S. National Survey of Children's Health 2011-2012. Journal of autism and developmental disorders. PMID: 27752862

November 7, 2016
12:30 AM
116 views

What The Future Will Hold

by Aurametrix team in Aurametrix Blog

Elections are bad for your health. More than half of Americans, independently of their party preference, are stressed about upcoming elections, especially the oldest and the youngest voters. Social media is one of the major factors making this stress even worse. ... Read more »

Stanton SJ, Beehner JC, Saini EK, Kuhn CM, & Labar KS. (2009) Dominance, politics, and physiology: voters' testosterone changes on the night of the 2008 United States presidential election. PloS one, 4(10). PMID: 19844583

Markey, P., & Markey, C. (2011) Pornography-seeking behaviors following midterm political elections in the United States: A replication of the challenge hypothesis. Computers in Human Behavior, 27(3), 1262-1264. DOI: 10.1016/j.chb.2011.01.007

Waismel-Manor I, Ifergane G, & Cohen H. (2011) When endocrinology and democracy collide: emotions, cortisol and voting at national elections. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 21(11), 789-95. PMID: 21482457

Blanton, H., Strauts, E., & Perez, M. (2012) Partisan Identification as a Predictor of Cortisol Response to Election News. Political Communication, 29(4), 447-460. DOI: 10.1080/10584609.2012.736239

Neiman J, Giuseffi K, Smith K, French J, Waismel-Manor I, & Hibbing J. (2015) Voting at Home Is Associated with Lower Cortisol than Voting at the Polls. PloS one, 10(9). PMID: 26335591

November 6, 2016
09:05 PM
98 views

Obama invades Europe: “Yes, we can!”

by Piter Boll in Earthling Nature

by Piter Kehoma Boll This information was known by me and some other people for quite a while, but only recently has caught attention of the general public. Obama is the newest threat in Europe. No, I’m not talking about the … Continue reading →... Read more »

Álvarez-Presas, M., Mateos, E., Tudó, À., Jones, H., & Riutort, M. (2014) Diversity of introduced terrestrial flatworms in the Iberian Peninsula: a cautionary tale. PeerJ. DOI: 10.7717/peerj.430

Boll, P., & Leal-Zanchet, A. (2016) Preference for different prey allows the coexistence of several land planarians in areas of the Atlantic Forest. Zoology, 119(3), 162-168. DOI: 10.1016/j.zool.2016.04.002

Carbayo, F., Álvarez-Presas, M., Jones, H., & Riutort, M. (2016) The true identity of Obama (Platyhelminthes: Geoplanidae) flatworm spreading across Europe. Zoological Journal of the Linnean Society, 177(1), 5-28. DOI: 10.1111/zoj.12358

November 5, 2016
04:20 AM
125 views

Sensory subtypes and anxiety and autism

by Paul Whiteley in Questioning Answers

"This is the first study to identify the existence of sensory subtypes among older children and adolescents with ASD [autism spectrum disorder] and explore their association with anxiety levels."Far be it from me to question the above quote provided in the paper by Mirko Uljarević and colleagues [1] but I'm inclined to suggest that there has already been some research published on the link between sensory issues and anxiety in the context of the autism spectrum before (see here and se........ Read more »

Uljarević M, Lane A, Kelly A, & Leekam S. (2016) Sensory subtypes and anxiety in older children and adolescents with autism spectrum disorder. Autism research : official journal of the International Society for Autism Research, 9(10), 1073-1078. PMID: 26765165

November 4, 2016
09:13 AM
128 views

Study shows that articles published in English attract more citations

by SciELO in SciELO in Perspective

Among the many factors that influence citation practice in scholarly communication, the language of publication plays a key role. A study by Argentine researchers showed that English articles receive more citations than those published in other languages. Despite being perceived by many as of lower quality and relevance, articles in Spanish from two Latin American journals were blind evaluated and were not, in fact, underqualified. … Read More →... Read more »

Di Bitetti, M., & Ferreras, J. (2016) Publish (in English) or perish: The effect on citation rate of using languages other than English in scientific publications. Ambio. DOI: 10.1007/s13280-016-0820-7

Meneghini, R., Packer, A., & Nassi-Calò, L. (2008) Articles by Latin American Authors in Prestigious Journals Have Fewer Citations. PLoS ONE, 3(11). DOI: 10.1371/journal.pone.0003804

Letchford, A., Moat, H., & Preis, T. (2015) The advantage of short paper titles. Royal Society Open Science, 2(8), 150266. DOI: 10.1098/rsos.150266

Meneghini, R., & Packer, A. (2007) Is there science beyond English? Initiatives to increase the quality and visibility of non-English publications might help to break down language barriers in scientific communication. EMBO reports, 8(2), 112-116. DOI: 10.1038/sj.embor.7400906

November 4, 2016
06:12 AM
105 views

Two recent case reports on BHD – Epidemiologic study of patients in Asia and new FLCN mutation

by Joana Guedes in BHD Research Blog

Furuya et al. (2016) present a new study describing genetic, epidemiologic and clinicopathologic features of 312 Asian individuals with BHD manifestations based on data from 120 probands from different families (119 Japanese and 1 Taiwanese), 36 siblingss with genetic testing and 156 siblings without genetic testing.... Read more »

Furuya M, Yao M, Tanaka R, Nagashima Y, Kuroda N, Hasumi H, Baba M, Matsushima J, Nomura F, & Nakatani Y. (2016) Genetic, epidemiologic and clinicopathologic studies of Japanese Asian patients with Birt-Hogg-Dubé syndrome. Clinical genetics, 90(5), 403-412. PMID: 27220747

November 4, 2016
05:00 AM
77 views

Friday Fellow: Silvergreen Moss

by Piter Boll in Earthling Nature

by Piter Kehoma Boll Found throughout most of the world, you probably have encountered this fellow many times in your life, but did not pay any attention. After all, it is just a moss! Scientifically known as Bryum argenteum and popularly … Continue reading →... Read more »

Sabovljevic, A., Sokovic, M., Sabovljevic, M., & Grubisic, D. (2006) Antimicrobial activity of Bryum argenteum. Fitoterapia, 77(2), 144-145. DOI: 10.1016/j.fitote.2005.11.002

Shaw, A., & Albright, D. (1990) Potential for the Evolution of Heavy Metal Tolerance in Bryum argenteum, a Moss. II. Generalized Tolerances among Diverse Populations. The Bryologist, 93(2), 187. DOI: 10.2307/3243622

November 4, 2016
04:03 AM
114 views

Hyperhomocysteinemia as a significant risk factor for autism?

by Paul Whiteley in Questioning Answers

The findings reported by Naushad Shaik Mohammad and colleagues [1] provide some blogging fodder today and the suggestion of a link between some of the genetics of the folate pathway and the finding of elevated levels of homocysteine with [some] autism in mind.OK, from the start, the genetics of folate metabolism mentioned in the context of autism typically means reference to the quite well replicated finding of issues with the gene methylenetetrahydrofolate reductase (MTHFR) (see ........ Read more »

Shaik Mohammad N, Sai Shruti P, Bharathi V, Krishna Prasad C, Hussain T, Alrokayan SA, Naik U, & Radha Rama Devi A. (2016) Clinical utility of folate pathway genetic polymorphisms in the diagnosis of autism spectrum disorders. Psychiatric genetics. PMID: 27755291

November 3, 2016
11:10 PM
129 views

Stereotyped ethnic names as a barrier to workplace entry

by Ingrid Piller in Language on the Move

Who of the three women in this image do you think German employers are most likely to consider as a...... Read more »

Arai, M., Bursell, M., & Nekby, L. (2016) The Reverse Gender Gap in Ethnic Discrimination: Employer Stereotypes of Men and Women with Arabic Names. International Migration Review, 50(2), 385-412. DOI: 10.1111/imre.12170

Piller, I. (2016) Language at work. Linguistic Diversity and Social Justice. DOI: 10.1093/acprof:oso/9780199937240.003.0004

November 3, 2016
01:49 PM
110 views

Does The Motor Cortex Inhibit Movement?

by Neuroskeptic in Neuroskeptic_Discover

A new paper could prompt a rethink of a basic tenet of neuroscience. It is widely believed that the motor cortex, a region of the cerebral cortex, is responsible for producing movements, by sending instructions to other brain regions and ultimately to the spinal cord. But according to neuroscientists Christian Laut Ebbesen and colleagues, the truth may be the opposite: the motor cortex may equally well suppress movements.

Ebbesen et al. studied the vibrissa motor cortex (VMC) of the rat, ... Read more »

Ebbesen CL, Doron G, Lenschow C, & Brecht M. (2016) Vibrissa motor cortex activity suppresses contralateral whisking behavior. Nature Neuroscience. PMID: 27798633

November 3, 2016
04:10 AM
136 views

Antibiotic brain part 3

by Paul Whiteley in Questioning Answers

"This study demonstrates an association between antibiotic use in the first year of life and subsequent neurocognitive outcomes in childhood."So said the findings reported by Slykerman and colleagues [1] who relied on data from the Auckland Birthweight Collaborative Study (an initiative set up to determine whether "internationally recognized risk factors for small-for-gestational-age (SGA) term babies were applicable in New Zealand") to examine the suggestion that early life antib........ Read more »

Slykerman RF, Thompson J, Waldie KE, Murphy R, Wall C, & Mitchell EA. (2016) Antibiotics in the first year of life and subsequent neurocognitive outcomes. Acta paediatrica (Oslo, Norway : 1992). PMID: 27701771

November 2, 2016
04:56 PM
110 views

When I read things like this...

by Craig Payne in Running Research Junkie

When I read things like this...... Read more »

Hollander K, Heidt C, van der Zwaard B, Braumann KM, & Zech A. (2016) Long-Term Effects of Habitual Barefoot Running and Walking: A Systematic Review. Medicine and science in sports and exercise. PMID: 27801744

Medicine

November 2, 2016
11:09 AM
120 views

Weight Training Boosts Brain Size and Performance

by William Yates, M.D. in Brain Posts

Aerobic exercise increases brain blood flow and has demonstrated beneficial effects on cognition.The effects of weight training exercise on the brain is less frequently studied. Hence, we know little about the effect and mechanism of weight training on brain function and performance.A recent study provides some needed insight on this topic.A study by C Suo and colleagues from Australia examined the effects of resistance training and cognitive skills training on brain structure and function.The k........ Read more »

Suo C, Singh MF, Gates N, Wen W, Sachdev P, Brodaty H, Saigal N, Wilson GC, Meiklejohn J, Singh N.... (2016) Therapeutically relevant structural and functional mechanisms triggered by physical and cognitive exercise. Molecular psychiatry, 21(11), 1645. PMID: 27090304

November 2, 2016
10:30 AM
113 views

Testing an Automated and Humane Way to Resolve Barking

by CAPB in Companion Animal Psychology Blog

Teaching a quiet behaviour using an automatic feeder is a promising solution to barking problems.Some dogs bark when their owner is out and they are left home alone. A recent study by Alexandra Protopopova (Texas Tech University) et al investigates the effectiveness of a humane, automated approach to solving barking problems.The research was conducted because some owners use citronella or shock collars to try and prevent their dogs from barking. While the devices may sometimes work, there ........ Read more »

Protopopova, A., Kisten, D., & Wynne, C. (2016) Evaluating a humane alternative to the bark collar: Automated differential reinforcement of not barking in a home-alone setting. Journal of Applied Behavior Analysis. DOI: 10.1002/jaba.334

November 2, 2016
04:30 AM
121 views

What Came First the Concussion Or the Lower Extremity Musculoskeletal Injury?

by Kyle Harris in Sports Medicine Research (SMR): In the Lab & In the Field

Athletes who reported sustaining a concussion were 1.6 to 2.9 times more likely to have also sustained a lower extremity musculoskeletal injury at the end of their intercollegiate athletic careers.... Read more »

Gilbert, F., Burdette, G., Joyner, A., Llewellyn, T., & Buckley, T. (2016) Association Between Concussion and Lower Extremity Injuries in Collegiate Athletes. Sports Health: A Multidisciplinary Approach, 8(6), 561-567. DOI: 10.1177/1941738116666509

November 2, 2016
03:55 AM
142 views

ADHD (symptoms) and pain

by Paul Whiteley in Questioning Answers

If a primary goal of medicine is to relieve pain and suffering then the paper by Andrew Stickley and colleagues [1] might provide an important insight into how medicine might be missing some important groups when it comes to the experience of pain "assessed by the degree to which it interfered with work activity in the previous month."Drawing on data from the English 2007 Adult Psychiatric Morbidity Survey (APMS) (a resource that has cropped up on this blog before), auth........ Read more »

Stickley A, Koyanagi A, Takahashi H, & Kamio Y. (2016) ADHD symptoms and pain among adults in England. Psychiatry research, 326-331. PMID: 27750114

November 1, 2016
09:01 AM
161 views

Multiwavelength study of 20 jets that emanate from the periphery of active regions by Sargam M. Mulay et al.*

by CESRA in Solar Radio Science

Solar jets are transient phenomena observed in the solar atmosphere. They appear as sharp-edged, impulsive, and collimated flows of plasma that move outwards with a bright spot at the footpoint, which forms an ‘inverted-Y’ topology of magnetic field lines. They are observed throughout the atmosphere i.e. in the photosphere (Hα, Ca II K [...]... Read more »

Mulay et al. (2006) Multiwavelength study of 20 jets that emanate from the periphery of active regions. Astronomy . info:/

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